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Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51.
Heijink AM, Stok C, Porubsky D, Manolika EM, de Kanter JK, Kok YP, Everts M, de Boer HR, Audrey A, Bakker FJ, Wierenga E, Tijsterman M, Guryev V, Spierings DCJ, Knipscheer P, van Boxtel R, Ray Chaudhuri A, Lansdorp PM, van Vugt MATM.
Nat Commun. 2022 Nov 7;13(1):6722. doi: 10.1038/s41467-022-34519-8.
Synthesis and in vitro biological evaluation of 3-ethyl-1,5-naphthyridin-2(1H)-one derivatives as potent PARP-1 selective inhibitors and PARP-1 DNA trappers.
Ren J, Quan X, Liu Y, Li J, Zhang X, Li Z, Zhang X.
Bioorg Med Chem Lett. 2022 Nov 4:129046. doi: 10.1016/j.bmcl.2022.129046. Epub ahead of print.