Angelina Jolie Effect on Uptake
~ Genetics of Breast & Ovarian Cancer

Any aspect of the "Angelina Jolie Effect", particularly on increased uptake of various genetic services related to breast/ovarian cancer risk; includes responses of genetics professionals and other health care providers

List was last updated on Apr 21, 2021 @ 12:24 am.


    • Trends and timing of risk-reducing mastectomy uptake in unaffected BRCA1 and BRCA2 carriers in Slovenia.
    • Ložar T, Žgajnar J, Perhavec A, Blatnik A, Novakovic S, Krajc M.
    • Eur J Surg Oncol. 2021 Mar 26:S0748-7983(21)00393-0. doi: 10.1016/j.ejso.2021.03.248. Epub ahead of print.
    • The Angelina Jolie effect: Contralateral risk-reducing mastectomy trends in patients at increased risk of breast cancer.
    • Basu NN, Hodson J, Chatterjee S, Gandhi A, Wisely J, Harvey J, Highton L, Murphy J, Barnes N, Johnson R, Barr L, Kirwan CC, Howell S, Baildam AD, Howell A, Evans DG.
    • Sci Rep. 2021 Feb 2;11(1):2847. doi: 10.1038/s41598-021-82654-x.
    • Celebrities Share Their Breast Cancer Stories.
    • [No author given]
    • My Gene Counsel. Genetic Journal. 2020 Oct 7.
    • Implications of celebrity endorsement of prostate cancer awareness in a tertiary referral unit- The "Fry-Turnbull" Effect.
    • Lovegrove CE, Musbahi O, Ranasinha N, Omer A, Lopez F, Campbell A, Bryant RJ, Leslie T, Bell R, Brewster S, Hamdy FC, Wright B, Lamb AD.
    • BJU Int. 2020 Jan 7. doi: 10.1111/bju.14992. [Epub ahead of print]
    • Commentary
    • Trends in BRCA testing and socioeconomic deprivation.
    • Martin AP, Pedra G, Downing J, Collins B, Godman B, Alfirevic A, Pirmohamed M, Lynn Greenhalgh K.
    • Eur J Hum Genet. 2019 May 3. doi: 10.1038/s41431-019-0424-3. [Epub ahead of print]
    • Current knowledge of risk reducing mastectomy: Indications, techniques, results, benefits, harms.
    • Baildam AD.
    • Breast. 2019 Mar 29;46:48-51. doi: 10.1016/j.breast.2019.03.011. [Epub ahead of print]
    • Review
    • College Women's Responses to a Celebrity Health Disclosure.
    • Drizin JH, Malcarne VL, Schiaffino MK, Wells KJ.
    • Health Commun. 2018 Oct;33(10):1302-1307. doi: 10.1080/10410236.2017.1351276. Epub 2017 Aug 18.
    • Risk-reducing mastectomy rates in the US: a closer examination of the Angelina Jolie effect.
    • Liede A, Cai M, Crouter TF, Niepel D, Callaghan F, Evans DG.
    • Breast Cancer Res Treat. 2018 Sep;171(2):435-442. doi: 10.1007/s10549-018-4824-9. Epub 2018 May 28.
    • Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population.
    • Manchanda R, Blyuss O, Gaba F, Gordeev VS, Jacobs C, Burnell M, Gan C, Taylor R, Turnbull C, Legood R, Zaikin A, Antoniou AC, Menon U, Jacobs I.
    • J Med Genet. 2018 Aug;55(8):538-545. doi: 10.1136/jmedgenet-2017-105195. Epub 2018 Apr 5.
    • Direct-to-Consumer Genetic Testing: The Implications of the US FDA's First Marketing Authorization for BRCA Mutation Testing.
    • Gill J, Obley AJ, Prasad V.
    • JAMA. 2018 Jun 19;319(23):2377-2378. doi: 10.1001/jama.2018.5330.
    • Commentary
    • Angelina's Impact: Advocates Share.
    • [No author given]
    • My Gene Counsel. 2018 May 14.
    • Angelina's Impact: Genetic Counselors Share.
    • [No author given]
    • My Gene Counsel. 2018 May 14.
    • Trends in utilization and costs of BRCA testing among women aged 18-64 years in the United States, 2003-2014.
    • Chen Z, Kolor K, Grosse SD, Rodriguez JL, Lynch JA, Green RF, Dotson WD, Bowen MS, Khoury MJ.
    • Genet Med. 2018 Apr;20(4):428-434. doi: 10.1038/gim.2017.118. Epub 2017 Sep 21.
    • The risk of unjustified BRCA testing after the "Angelina Jolie effect": how can we save (laboratory) medicine from the Internet?
    • Lippi G.
    • Clin Chem Lab Med. 2018 Jan 26;56(2):e33-e35. doi: 10.1515/cclm-2017-0551.
    • Letter
    • Use of BRCA Mutation Test in the U.S., 2004-2014.
    • Guo F, Hirth JM, Lin YL, Richardson G, Levine L, Berenson AB, Kuo YF.
    • Am J Prev Med. 2017 Jun;52(6):702-709. doi: 10.1016/j.amepre.2017.01.027. Epub 2017 Mar 22.

    Press: BRCA Testing Has Skyrocketed, but Misses High-Risk Women. (Medscape)

    Letter, Comment:

    Increased Use of BRCA Mutation Test in Unaffected Women Over the Period 2004-2014 in the U.S.: Further Evidence of the "Angelina Jolie Effect"?

    Letter, Reply:

    Authors' Response: "Angelina Jolie Effect" on the Shifting Role of BRCA Testing in the U.S.

    • Familial breast cancer: Genetic counseling over time, including patients´ expectations and initiators considering the Angelina Jolie effect.
    • Evers C, Fischer C, Dikow N, Schott S.
    • PLoS One. 2017 May 25;12(5):e0177893. doi: 10.1371/journal.pone.0177893. eCollection 2017.
    • The effect of a celebrity health disclosure on demand for health care: trends in BRCA testing and subsequent health services use.
    • Roberts MC, Dusetzina SB.
    • J Community Genet. 2017 Apr;8(2):141-146. doi: 10.1007/s12687-017-0295-7. Epub 2017 Mar 15.
    • A Retrospective Exploration of the Impact of the 'Angelina Jolie Effect' on the Single State-Wide Familial Cancer Program in Perth, Western Australia.
    • Freedman R, Mountain H, Karina D, Schofield L.
    • J Genet Couns. 2017 Feb;26(1):52-62. doi: 10.1007/s10897-016-9982-5. Epub 2016 Jun 6.
    • "Angelina Jolie Effect”: What Should I Know About Hereditary Cancer and Testing?
    • Erica Ramos.
    • NSGC Blog. 2017 Jan 18.
    • Blog post
    • Do celebrity endorsements matter? Observational study of BRCA gene testing and mastectomy rates after Angelina Jolie's New York Times editorial.
    • Desai S, Jena AB.
    • BMJ. 2016 Dec 14;355:i6357. doi: 10.1136/bmj.i6357.

    Research News:

    Angelina Jolie's mastectomy triggered sharp rise in gene testing.

    Research News: Angelina Jolie spoke out on BRCA testing: Did genetic testing increase? (FORCE)

    Blog post: "Angelina Jolie Effect”: What Should I Know About Hereditary Cancer and Testing? (NSGC Blog)

    Research News: Were women foolish to follow Angelina Jolie into BRCA cancer gene testing? (STAT)

    Research News: Jolie Effect: BRCA Tests Up but No Change in Mastectomy. (Medscape)

    • Angelina and Brad effect.
    • Eisinger F.
    • Fam Cancer. 2016 Oct;15(4):541-2. doi: 10.1007/s10689-016-9908-2.
    • Letter
    • Celebrity Health Announcements and Online Health Information Seeking: An Analysis of Angelina Jolie's Preventative Health Decision.
    • Dean M.
    • Health Commun. 2016 Jun;31(6):752-61. doi: 10.1080/10410236.2014.995866. Epub 2015 Nov 17.
    • Angelina's Impact: Genetic Counselors Share.
    • [No author given]
    • My Gene Counsel. 2016 May 14.
    • Angelina's Impact: Advocates Share.
    • [No author given]
    • My Gene Counsel. 2016 May 14.
    • Celebrity Influence and Identification: A Test of the Angelina Effect.
    • Kosenko KA, Binder AR, Hurley R.
    • J Health Commun. 2016 Mar;21(3):318-26. doi: 10.1080/10810730.2015.1064498. Epub 2016 Jan 15.
    • Has the Angelina Jolie effect led to an increase in risk reducing mastectomy and breast reconstruction in Wales: A retrospective, single centre cohort study.
    • Malcolm CM, Javed MU, Nguyen D.
    • J Plast Reconstr Aesthet Surg. 2016 Feb;69(2):288-9. doi: 10.1016/j.bjps.2015.10.018. Epub 2015 Oct 26.
    • Letter
    • Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women.
    • Evans DG, Wisely J, Clancy T, Lalloo F, Wilson M, Johnson R, Duncan J, Barr L, Gandhi A, Howell A.
    • Breast Cancer Res. 2015 Nov 25;17:143. doi: 10.1186/s13058-015-0650-8.

    The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.

    Blog post: The Angelina Jolie effect (BioMed Central)

    • The Angelina effect revisited: Exploring a media-related impact on public awareness.
    • Lebo PB, Quehenberger F, Kamolz LP, Lumenta DB.
    • Cancer. 2015 Nov 15;121(22):3959-3964. doi: 10.1002/cncr.29461. Epub 2015 Sep 28.
    • Education Program to Increase Awareness of Genetic Testing Launched.
    • [No author given]
    • Clinical OMICs. 2015 Sep 21.
    • The Angelina Effect and the Mixed Blessing of Celebrities and Risk Awareness.
    • Hilda Bastian.
    • Absolutely Maybe. PLoS Blogs. 2015 Aug 9.
    • Celebrity disclosures and information seeking: the case of Angelina Jolie.
    • Juthe RH, Zaharchuk A, Wang C.
    • Genet Med. 2015 Jul 2;17(7):545-553. doi: 10.1038/gim.2014.141. Epub 2014 Oct 23.
    • Risk assessment: Physicians discuss motivations for rising rates of prophylactic mastectomies.
    • Printz C.
    • Cancer. 2015 Jun 1;121(11):1721-2. doi: 10.1002/cncr.28996.
    • Discussion: Sex After Oophorectomy, Hysterectomy.
    • Mel Majoros, Ellen T. Matloff, Amy Byer Shainman, Georgia Hurst.
    • My Gene Counsel / The Cancer Warrior. 2015 May 5.
    • 20 Years Since BRCA2: Where Are We Now in Cancer Screening?
    • Eric J. Topol, Nazneen Rahman.
    • Medscape, Eric Topol on Medscape, Medscape One-on-One. 2015 Apr 13.
    • Discussion: Sex After Oophorectomy, Hysterectomy.
    • [No author given]
    • My Gene Counsel. 2015 Apr 7.
    • Experts Support Jolie's Prophylactic Surgery Decision
    • Zosia Chustecka
    • Medscape Medical News, Medscape Oncology, 2015 Mar 27.
    • Angelina Jolie Pitt's Op-ed This Week Sparks Wider Discussion on Hereditary Cancer.
    • [No author given]
    • My Gene Counsel. 2015 Mar 26.
    • Gene counsellors expect resurgence of 'Jolie effect'
    • Erika Check Hayden
    • Nature, News. 2015 Mar 26. doi: 10.1038/nature.2015.17184.
    • Doctors: Angelina Jolie did the right thing
    • Elizabeth Cohen.
    • CNN, 2015 Mar 25.
    • Learning from Angelina Jolie's genetic testing for our own health.
    • Elizabeth Cohen
    • CNN, 2015 Mar 25.
    • Angelina Jolie's message was 'choose what's right for you,' and experts agree.
    • Christine Mai-Duc
    • LA Times, 2015 Mar 24.
    • Angelina Jolie Pitt: Diary of a Surgery.
    • Angelina Jolie Pitt
    • NY Times, 2015 Mar 24.
    • Lizzie Stark's ‘Real Steps to Survival’
    • Seth Berkman
    • The Sisterhood, 2015 Jan 6
    • Angelina Jolie and medical decision science.
    • Bhatti J, Redelmeier DA.
    • Med Decis Making. 2015 Jan;35(1):4-5. doi: 10.1177/0272989X14558882. Epub 2014 Nov 5.
    • Cancer information seeking in the digital age: effects of Angelina Jolie's prophylactic mastectomy announcement.
    • Noar SM, Althouse BM, Ayers JW, Francis DB, Ribisl KM.
    • Med Decis Making. 2015 Jan;35(1):16-21. doi: 10.1177/0272989X14556130. Epub 2014 Oct 27.
    • Universal BRCA Testing 'Would Break the Bank'.
    • Roxanne Nelson.
    • Medscape Oncology, 2014 Dec 15.
    • [Breast cancer: prophylactic mastectomy and the "Angelina Jolie" effect].
    • Nau JY.
    • Rev Med Suisse. 2014 Oct 1;10(444):1844-5.
    • The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.
    • Evans DG, Barwell J, Eccles DM, Collins A, Izatt L, Jacobs C, Donaldson A, Brady AF, Cuthbert A, Harrison R, Thomas S, Howell A; The FH02 Study Group; RGC teams, Miedzybrodzka Z, Murray A; The FH02 Study Group; RGC Teams.
    • Breast Cancer Res. 2014 Sep 19;16(5):442. doi: 10.1186/s13058-014-0442-6.

    Comment, Letter:

    Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women.

    • 'Angelina Jolie Effect': BRCA Testing Doubles.
    • Zosia Chustecka.
    • Medscape Medical News. Conference News. from the 2014 Breast Cancer Symposium. 2014 Sep 3.

    Conference abstract: The impact of Angelina Jolie's (AJ) story on genetic referral and testing at an academic cancer centre. (ASCO University. Meeting Library.)

    • Angelina Jolie’s Surgery May Have Doubled Genetic Testing Rates at One Clinic.
    • Alexandra Sifferlin.
    • Time. 2014 Sep 2.

    Conference abstract: The impact of Angelina Jolie's (AJ) story on genetic referral and testing at an academic cancer centre. (ASCO University. Meeting Library.)

    Press article:

    The Angelina effect.

    • The Role of Testing for BRCA1 and BRCA2 Mutations in Cancer Prevention.
    • McCarthy AM, Armstrong K.
    • JAMA Intern Med. 2014 Jul 1;174(7):1023-4. doi: 10.1001/jamainternmed.2014.1322.
    • The Angelina effect: immediate reach, grasp, and impact of going public.
    • Borzekowski DL, Guan Y, Smith KC, Erby LH, Roter DL.
    • Genet Med. 2014 Jul;16(7):516-21. doi: 10.1038/gim.2013.181. Epub 2013 Dec 19.

    Introductory article:

    In this Issue.

    Podcast: Genetics in Medicine, Celebrities, Genetics and Tough Decisions: the Angelina Effect. (Genetics in Medicine GenePod)

    Archive

    Press: Angelina Didn't Help Educate People About Breast Cancer Risk. (NPR. Your Health. Shots.)

    • Angelina Jolie's faulty gene: newspaper coverage of a celebrity's preventive bilateral mastectomy in Canada, the United States, and the United Kingdom.
    • Kamenova K, Reshef A, Caulfield T.
    • Genet Med. 2014 Jul;16(7):522-8. doi: 10.1038/gim.2013.199. Epub 2013 Dec 19.

    Introductory article:

    In this Issue.

    Podcast: Genetics in Medicine, Celebrities, Genetics and Tough Decisions: the Angelina Effect. (Genetics in Medicine GenePod)

    Archive

    Press: Angelina Didn't Help Educate People About Breast Cancer Risk. (NPR. Your Health. Shots.)

    • Survey Finds More Inquiries to Genetic Counselors, Including From the “Worried-Well”.
    • Christina Izzo.
    • Oncology Nursing News. 2014 Jun 9.
    • Angelina Jolie Effect: One Year Later.
    • Joy Larsen Haidle.
    • NSGC Blog. 2014 May 14.
    • [Angelina Jolie Pitt, saint and modern martyr].
    • Nau JY.
    • Rev Med Suisse. 2015 Apr 1;11(468):794-5.
    • [Article in French]
    • After Angelina and the Supreme Court Decision, where do we go from here? BRCA gene testing in Rhode Island's Portuguese population.
    • Benson C, Stobie L, Shur N, Yuan Z, Teixeira MR, Chung M.
    • Am J Med Genet A. 2014 Feb;164(2):557-8. doi: 10.1002/ajmg.a.36254. Epub 2013 Dec 5.
    • Did we need a new Angelina Jolie to discuss about prophylactic surgery for colon cancer because of Mister Lynch's silence?
    • Pocard M.
    • J Visc Surg. 2014 Feb;151(1):1-2. doi: 10.1016/j.jviscsurg.2013.11.001. Epub 2013 Dec 25.
    • Biography, Editorial
    • Angelina's choice: private decision, public impact.
    • Sirohi B, Sinha N, Goel NS, Badwe RA.
    • Indian J Med Ethics. 2014 Jan-Mar;11(1):34-5.
    • In the wake of Angelina - managing a family history of breast cancer.
    • Dunlop K, Kirk J, Tucker K.
    • Aust Fam Physician. 2014 Jan-Feb;43(1):76-8.
    • The importance of understanding the psychological meaning of Angelina Jolie's surgery.
    • Goin MK.
    • J Psychiatr Pract. 2014 Jan;20(1):61-2. doi: 10.1097/01.pra.0000442939.69198.0c.
    • Honing the Health Message on BRCA Mutations.
    • Schmidt C.
    • J Natl Cancer Inst. 2013 Dec 18;105(24):1843-4. doi: 10.1093/jnci/djt364. Epub 2013 Dec 6.
    • Increase in breast cancer gene screening: the Angelina Jolie effect.
    • Deborah Kotz.
    • Boston Globe. 2013 Dec 3.
    • The Angelina Jolie effect.
    • James PA, Mitchell G, Bogwitz M, Lindeman GJ.
    • Med J Aust. 2013 Nov 18;199(10):646.
    • Biography, Historical Article
    • Angelina's choice.
    • Goel NS.
    • South Asian J Cancer. 2013 Oct;2(4):285-7. doi: 10.4103/2278-330X.119903.
    • 'The Angelina Jolie Effect' symposium offers inspiration, information.
    • [No author given]
    • Yale Cancer Genetic Counseling. 2013 Sep 26.
    • Risk management: Jolie's decision sparks debate, need for more education.
    • Trossman S.
    • Am Nurse. 2013 Jul-Aug;45(4):1, 6.
    • Lou Gehrig, Angelina Jolie, and cancer genetics.
    • Burstein HJ.
    • J Natl Compr Canc Netw. 2013 Jun 1;11(6):631-2.
    • Editorial
    • The Angelina effect.
    • Kluger J, Park A.
    • Time. 2013 May 27;181(20):28-33.
    • Press article
    • Angelina Jolie's double mastectomy and the question of who owns our genes.
    • Hurley R.
    • BMJ. 2013 May 22;346:f3340. doi: 10.1136/bmj.f3340.
    • Editorial / Commentary
    • Celebrity impact. Benefits, risks seen in hype over Jolie's disclosure.
    • Lee J.
    • Mod Healthc. 2013 May 20;43(20):10-1.
    • Angelina Jolie's Mastectomy: BRCA Testing in the Spotlight.
    • Kate Johnson.
    • Medscape Medical News. Oncology. 2013 May 16.
    • My Medical Choice.
    • Angelina Jolie.
    • NY Times. The Opinion Pages. 2013 May 14.