Angelina Jolie Effect on Uptake
~ Genetics of Breast & Ovarian Cancer

Any aspect of the "Angelina Jolie Effect", particularly on increased uptake of various genetic services related to breast/ovarian cancer risk; includes responses of genetics professionals and other health care providers

List was last updated on May 15, 2019 @ 3:45 am.


    • Trends in BRCA testing and socioeconomic deprivation.
    • Martin AP, Pedra G, Downing J, Collins B, Godman B, Alfirevic A, Pirmohamed M, Lynn Greenhalgh K.
    • Eur J Hum Genet. 2019 May 3. doi: 10.1038/s41431-019-0424-3. [Epub ahead of print]
    • Current knowledge of risk reducing mastectomy: Indications, techniques, results, benefits, harms.
    • Baildam AD.
    • Breast. 2019 Mar 29;46:48-51. doi: 10.1016/j.breast.2019.03.011. [Epub ahead of print]
    • Review
    • College Women's Responses to a Celebrity Health Disclosure.
    • Drizin JH, Malcarne VL, Schiaffino MK, Wells KJ.
    • Health Commun. 2018 Oct;33(10):1302-1307. doi: 10.1080/10410236.2017.1351276. Epub 2017 Aug 18.
    • Risk-reducing mastectomy rates in the US: a closer examination of the Angelina Jolie effect.
    • Liede A, Cai M, Crouter TF, Niepel D, Callaghan F, Evans DG.
    • Breast Cancer Res Treat. 2018 Sep;171(2):435-442. doi: 10.1007/s10549-018-4824-9. Epub 2018 May 28.
    • Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population.
    • Manchanda R, Blyuss O, Gaba F, Gordeev VS, Jacobs C, Burnell M, Gan C, Taylor R, Turnbull C, Legood R, Zaikin A, Antoniou AC, Menon U, Jacobs I.
    • J Med Genet. 2018 Aug;55(8):538-545. doi: 10.1136/jmedgenet-2017-105195. Epub 2018 Apr 5.
    • Direct-to-Consumer Genetic Testing: The Implications of the US FDA's First Marketing Authorization for BRCA Mutation Testing.
    • Gill J, Obley AJ, Prasad V.
    • JAMA. 2018 Jun 19;319(23):2377-2378. doi: 10.1001/jama.2018.5330.
    • Commentary
    • Angelina's Impact: Advocates Share.
    • [No author given]
    • My Gene Counsel. 2018 May 14.
    • Angelina's Impact: Genetic Counselors Share.
    • [No author given]
    • My Gene Counsel. 2018 May 14.
    • Trends in utilization and costs of BRCA testing among women aged 18-64 years in the United States, 2003-2014.
    • Chen Z, Kolor K, Grosse SD, Rodriguez JL, Lynch JA, Green RF, Dotson WD, Bowen MS, Khoury MJ.
    • Genet Med. 2018 Apr;20(4):428-434. doi: 10.1038/gim.2017.118. Epub 2017 Sep 21.
    • The risk of unjustified BRCA testing after the "Angelina Jolie effect": how can we save (laboratory) medicine from the Internet?
    • Lippi G.
    • Clin Chem Lab Med. 2018 Jan 26;56(2):e33-e35. doi: 10.1515/cclm-2017-0551.
    • Letter
    • Use of BRCA Mutation Test in the U.S., 2004-2014.
    • Guo F, Hirth JM, Lin YL, Richardson G, Levine L, Berenson AB, Kuo YF.
    • Am J Prev Med. 2017 Jun;52(6):702-709. doi: 10.1016/j.amepre.2017.01.027. Epub 2017 Mar 22.

    Press: BRCA Testing Has Skyrocketed, but Misses High-Risk Women. (Medscape)

    Letter, Comment:

    Increased Use of BRCA Mutation Test in Unaffected Women Over the Period 2004-2014 in the U.S.: Further Evidence of the "Angelina Jolie Effect"?

    Letter, Reply:

    Authors' Response: "Angelina Jolie Effect" on the Shifting Role of BRCA Testing in the U.S.

    • Familial breast cancer: Genetic counseling over time, including patients´ expectations and initiators considering the Angelina Jolie effect.
    • Evers C, Fischer C, Dikow N, Schott S.
    • PLoS One. 2017 May 25;12(5):e0177893. doi: 10.1371/journal.pone.0177893. eCollection 2017.
    • The effect of a celebrity health disclosure on demand for health care: trends in BRCA testing and subsequent health services use.
    • Roberts MC, Dusetzina SB.
    • J Community Genet. 2017 Apr;8(2):141-146. doi: 10.1007/s12687-017-0295-7. Epub 2017 Mar 15.
    • A Retrospective Exploration of the Impact of the 'Angelina Jolie Effect' on the Single State-Wide Familial Cancer Program in Perth, Western Australia.
    • Freedman R, Mountain H, Karina D, Schofield L.
    • J Genet Couns. 2017 Feb;26(1):52-62. doi: 10.1007/s10897-016-9982-5. Epub 2016 Jun 6.
    • "Angelina Jolie Effect”: What Should I Know About Hereditary Cancer and Testing?
    • Erica Ramos.
    • NSGC Blog. 2017 Jan 18.
    • Blog post
    • Do celebrity endorsements matter? Observational study of BRCA gene testing and mastectomy rates after Angelina Jolie's New York Times editorial.
    • Desai S, Jena AB.
    • BMJ. 2016 Dec 14;355:i6357. doi: 10.1136/bmj.i6357.

    Research News:

    Angelina Jolie's mastectomy triggered sharp rise in gene testing.

    Research News: Angelina Jolie spoke out on BRCA testing: Did genetic testing increase? (FORCE)

    Blog post: "Angelina Jolie Effect”: What Should I Know About Hereditary Cancer and Testing? (NSGC Blog)

    Research News: Were women foolish to follow Angelina Jolie into BRCA cancer gene testing? (STAT)

    Research News: Jolie Effect: BRCA Tests Up but No Change in Mastectomy. (Medscape)

    • Angelina and Brad effect.
    • Eisinger F.
    • Fam Cancer. 2016 Oct;15(4):541-2. doi: 10.1007/s10689-016-9908-2.
    • Letter
    • Celebrity Health Announcements and Online Health Information Seeking: An Analysis of Angelina Jolie's Preventative Health Decision.
    • Dean M.
    • Health Commun. 2016 Jun;31(6):752-61. doi: 10.1080/10410236.2014.995866. Epub 2015 Nov 17.
    • Angelina's Impact: Genetic Counselors Share.
    • [No author given]
    • My Gene Counsel. 2016 May 14.
    • Angelina's Impact: Advocates Share.
    • [No author given]
    • My Gene Counsel. 2016 May 14.
    • Celebrity Influence and Identification: A Test of the Angelina Effect.
    • Kosenko KA, Binder AR, Hurley R.
    • J Health Commun. 2016 Mar;21(3):318-26. doi: 10.1080/10810730.2015.1064498. Epub 2016 Jan 15.
    • Has the Angelina Jolie effect led to an increase in risk reducing mastectomy and breast reconstruction in Wales: A retrospective, single centre cohort study.
    • Malcolm CM, Javed MU, Nguyen D.
    • J Plast Reconstr Aesthet Surg. 2016 Feb;69(2):288-9. doi: 10.1016/j.bjps.2015.10.018. Epub 2015 Oct 26.
    • Letter
    • Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women.
    • Evans DG, Wisely J, Clancy T, Lalloo F, Wilson M, Johnson R, Duncan J, Barr L, Gandhi A, Howell A.
    • Breast Cancer Res. 2015 Nov 25;17:143. doi: 10.1186/s13058-015-0650-8.

    The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.

    Blog post: The Angelina Jolie effect (BioMed Central)

    • The Angelina effect revisited: Exploring a media-related impact on public awareness.
    • Lebo PB, Quehenberger F, Kamolz LP, Lumenta DB.
    • Cancer. 2015 Nov 15;121(22):3959-3964. doi: 10.1002/cncr.29461. Epub 2015 Sep 28.
    • Education Program to Increase Awareness of Genetic Testing Launched.
    • [No author given]
    • Clinical OMICs. 2015 Sep 21.
    • The Angelina Effect and the Mixed Blessing of Celebrities and Risk Awareness.
    • Hilda Bastian.
    • Absolutely Maybe. PLoS Blogs. 2015 Aug 9.
    • Celebrity disclosures and information seeking: the case of Angelina Jolie.
    • Juthe RH, Zaharchuk A, Wang C.
    • Genet Med. 2015 Jul 2;17(7):545-553. doi: 10.1038/gim.2014.141. Epub 2014 Oct 23.
    • Risk assessment: Physicians discuss motivations for rising rates of prophylactic mastectomies.
    • Printz C.
    • Cancer. 2015 Jun 1;121(11):1721-2. doi: 10.1002/cncr.28996.
    • Discussion: Sex After Oophorectomy, Hysterectomy.
    • Mel Majoros, Ellen T. Matloff, Amy Byer Shainman, Georgia Hurst.
    • My Gene Counsel / The Cancer Warrior. 2015 May 5.
    • 20 Years Since BRCA2: Where Are We Now in Cancer Screening?
    • Eric J. Topol, Nazneen Rahman.
    • Medscape, Eric Topol on Medscape, Medscape One-on-One. 2015 Apr 13.
    • Discussion: Sex After Oophorectomy, Hysterectomy.
    • [No author given]
    • My Gene Counsel. 2015 Apr 7.
    • Experts Support Jolie's Prophylactic Surgery Decision
    • Zosia Chustecka
    • Medscape Medical News, Medscape Oncology, 2015 Mar 27.
    • Angelina Jolie Pitt's Op-ed This Week Sparks Wider Discussion on Hereditary Cancer.
    • [No author given]
    • My Gene Counsel. 2015 Mar 26.
    • Gene counsellors expect resurgence of 'Jolie effect'
    • Erika Check Hayden
    • Nature, News. 2015 Mar 26. doi: 10.1038/nature.2015.17184.
    • Doctors: Angelina Jolie did the right thing
    • Elizabeth Cohen.
    • CNN, 2015 Mar 25.
    • Learning from Angelina Jolie's genetic testing for our own health.
    • Elizabeth Cohen
    • CNN, 2015 Mar 25.
    • Angelina Jolie's message was 'choose what's right for you,' and experts agree.
    • Christine Mai-Duc
    • LA Times, 2015 Mar 24.
    • Angelina Jolie Pitt: Diary of a Surgery.
    • Angelina Jolie Pitt
    • NY Times, 2015 Mar 24.
    • Lizzie Stark's ‘Real Steps to Survival’
    • Seth Berkman
    • The Sisterhood, 2015 Jan 6
    • Angelina Jolie and medical decision science.
    • Bhatti J, Redelmeier DA.
    • Med Decis Making. 2015 Jan;35(1):4-5. doi: 10.1177/0272989X14558882. Epub 2014 Nov 5.
    • Cancer information seeking in the digital age: effects of Angelina Jolie's prophylactic mastectomy announcement.
    • Noar SM, Althouse BM, Ayers JW, Francis DB, Ribisl KM.
    • Med Decis Making. 2015 Jan;35(1):16-21. doi: 10.1177/0272989X14556130. Epub 2014 Oct 27.
    • Universal BRCA Testing 'Would Break the Bank'.
    • Roxanne Nelson.
    • Medscape Oncology, 2014 Dec 15.
    • [Breast cancer: prophylactic mastectomy and the "Angelina Jolie" effect].
    • Nau JY.
    • Rev Med Suisse. 2014 Oct 1;10(444):1844-5.
    • The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services.
    • Evans DG, Barwell J, Eccles DM, Collins A, Izatt L, Jacobs C, Donaldson A, Brady AF, Cuthbert A, Harrison R, Thomas S, Howell A; The FH02 Study Group; RGC teams, Miedzybrodzka Z, Murray A; The FH02 Study Group; RGC Teams.
    • Breast Cancer Res. 2014 Sep 19;16(5):442. doi: 10.1186/s13058-014-0442-6.

    Comment, Letter:

    Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women.

    • 'Angelina Jolie Effect': BRCA Testing Doubles.
    • Zosia Chustecka.
    • Medscape Medical News. Conference News. from the 2014 Breast Cancer Symposium. 2014 Sep 3.

    Conference abstract: The impact of Angelina Jolie's (AJ) story on genetic referral and testing at an academic cancer centre. (ASCO University. Meeting Library.)

    • Angelina Jolie’s Surgery May Have Doubled Genetic Testing Rates at One Clinic.
    • Alexandra Sifferlin.
    • Time. 2014 Sep 2.

    Conference abstract: The impact of Angelina Jolie's (AJ) story on genetic referral and testing at an academic cancer centre. (ASCO University. Meeting Library.)

    Press article:

    The Angelina effect.

    • The Role of Testing for BRCA1 and BRCA2 Mutations in Cancer Prevention.
    • McCarthy AM, Armstrong K.
    • JAMA Intern Med. 2014 Jul 1;174(7):1023-4. doi: 10.1001/jamainternmed.2014.1322.
    • The Angelina effect: immediate reach, grasp, and impact of going public.
    • Borzekowski DL, Guan Y, Smith KC, Erby LH, Roter DL.
    • Genet Med. 2014 Jul;16(7):516-21. doi: 10.1038/gim.2013.181. Epub 2013 Dec 19.

    Introductory article:

    In this Issue.

    Podcast: Genetics in Medicine, Celebrities, Genetics and Tough Decisions: the Angelina Effect. (Genetics in Medicine GenePod)

    Archive

    Press: Angelina Didn't Help Educate People About Breast Cancer Risk. (NPR. Your Health. Shots.)

    • Angelina Jolie's faulty gene: newspaper coverage of a celebrity's preventive bilateral mastectomy in Canada, the United States, and the United Kingdom.
    • Kamenova K, Reshef A, Caulfield T.
    • Genet Med. 2014 Jul;16(7):522-8. doi: 10.1038/gim.2013.199. Epub 2013 Dec 19.

    Introductory article:

    In this Issue.

    Podcast: Genetics in Medicine, Celebrities, Genetics and Tough Decisions: the Angelina Effect. (Genetics in Medicine GenePod)

    Archive

    Press: Angelina Didn't Help Educate People About Breast Cancer Risk. (NPR. Your Health. Shots.)

    • Survey Finds More Inquiries to Genetic Counselors, Including From the “Worried-Well”.
    • Christina Izzo.
    • Oncology Nursing News. 2014 Jun 9.
    • Angelina Jolie Effect: One Year Later.
    • Joy Larsen Haidle.
    • NSGC Blog. 2014 May 14.
    • [Angelina Jolie Pitt, saint and modern martyr].
    • Nau JY.
    • Rev Med Suisse. 2015 Apr 1;11(468):794-5.
    • [Article in French]
    • After Angelina and the Supreme Court Decision, where do we go from here? BRCA gene testing in Rhode Island's Portuguese population.
    • Benson C, Stobie L, Shur N, Yuan Z, Teixeira MR, Chung M.
    • Am J Med Genet A. 2014 Feb;164(2):557-8. doi: 10.1002/ajmg.a.36254. Epub 2013 Dec 5.
    • Did we need a new Angelina Jolie to discuss about prophylactic surgery for colon cancer because of Mister Lynch's silence?
    • Pocard M.
    • J Visc Surg. 2014 Feb;151(1):1-2. doi: 10.1016/j.jviscsurg.2013.11.001. Epub 2013 Dec 25.
    • Biography, Editorial
    • Angelina's choice: private decision, public impact.
    • Sirohi B, Sinha N, Goel NS, Badwe RA.
    • Indian J Med Ethics. 2014 Jan-Mar;11(1):34-5.
    • In the wake of Angelina - managing a family history of breast cancer.
    • Dunlop K, Kirk J, Tucker K.
    • Aust Fam Physician. 2014 Jan-Feb;43(1):76-8.
    • The importance of understanding the psychological meaning of Angelina Jolie's surgery.
    • Goin MK.
    • J Psychiatr Pract. 2014 Jan;20(1):61-2. doi: 10.1097/01.pra.0000442939.69198.0c.
    • Honing the Health Message on BRCA Mutations.
    • Schmidt C.
    • J Natl Cancer Inst. 2013 Dec 18;105(24):1843-4. doi: 10.1093/jnci/djt364. Epub 2013 Dec 6.
    • Increase in breast cancer gene screening: the Angelina Jolie effect.
    • Deborah Kotz.
    • Boston Globe. 2013 Dec 3.
    • The Angelina Jolie effect.
    • James PA, Mitchell G, Bogwitz M, Lindeman GJ.
    • Med J Aust. 2013 Nov 18;199(10):646.
    • Biography, Historical Article
    • Angelina's choice.
    • Goel NS.
    • South Asian J Cancer. 2013 Oct;2(4):285-7. doi: 10.4103/2278-330X.119903.
    • 'The Angelina Jolie Effect' symposium offers inspiration, information.
    • [No author given]
    • Yale Cancer Genetic Counseling. 2013 Sep 26.
    • Risk management: Jolie's decision sparks debate, need for more education.
    • Trossman S.
    • Am Nurse. 2013 Jul-Aug;45(4):1, 6.
    • Lou Gehrig, Angelina Jolie, and cancer genetics.
    • Burstein HJ.
    • J Natl Compr Canc Netw. 2013 Jun 1;11(6):631-2.
    • Editorial
    • The Angelina effect.
    • Kluger J, Park A.
    • Time. 2013 May 27;181(20):28-33.
    • Press article
    • Angelina Jolie's double mastectomy and the question of who owns our genes.
    • Hurley R.
    • BMJ. 2013 May 22;346:f3340. doi: 10.1136/bmj.f3340.
    • Editorial / Commentary
    • Celebrity impact. Benefits, risks seen in hype over Jolie's disclosure.
    • Lee J.
    • Mod Healthc. 2013 May 20;43(20):10-1.
    • Angelina Jolie's Mastectomy: BRCA Testing in the Spotlight.
    • Kate Johnson.
    • Medscape Medical News. Oncology. 2013 May 16.
    • My Medical Choice.
    • Angelina Jolie.
    • NY Times. The Opinion Pages. 2013 May 14.