Category: Sequencing Technology

• Development and Clinical Applications of an Enclosed Automated Targeted NGS Library Preparation System.
• Shi C, Feng Y, Sun R, Chen J, Zhao Y, Wang Z, Xie S, Zhou J, Yang L, Cao X, Feng J, Zhang C, Wei B, Wang X, Chang Y, Zhao J, Wang Z, Zheng J, Liu J, Chantratita W, Xiong L, Zhang D, Chen C, Ma J.
• Clin Chim Acta. 2023 Jan 7:117224. doi: 10.1016/j.cca.2023.117224. Epub ahead of print.

• PMID: 36627008
• PubMed abstract
• Source abstract

• DNA Repair Deficiency as Circulating Biomarker in Prostate Cancer.
• Roviello G, Generali D, Gatti M, Riboli B, Paganini L, Nesi G, Catalano M.
• Front Oncol. 2023 Jan 12;12:1115241. doi: 10.3389/fonc.2023.1115241.

• Review
• Free Full Text

• DNA Repair Deficiency as Circulating Biomarker in Prostate Cancer.
• Roviello G, Generali D, Gatti M, Riboli B, Paganini L, Nesi G, Catalano M.
• Front Oncol. 2023 Jan 12;12:1115241. doi: 10.3389/fonc.2023.1115241.

• Review
• Free Full Text

• Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq.
• Akbari V, Hanlon VCT, O’Neill K, Lefebvre L, Schrader KA, Lansdorp PM, Jones SJM.
• Cell Genom. 2021 Dec 21. doi: 10.1016/j.xgen.2022.100233. Epub ahead of print.

• Free Full Text

Related:

•• Research news: Genetic Test Identifies Parental Source of Cancer Variant. (Medscape Oncology)

• Cytopathological assessment is an accurate method for identifying immunophenotypic features and BRCA1/2 mutations of high-grade serous carcinoma from ascites.
• Miceska S, Škof E, Novakovic S, Stegel V, Jericevic A, Grcar Kuzmanov B, Smrkolj Š, Cvjeticanin B, Bebar S, Globocnik Kukovica M, Kloboves-Prevodnik V.
• Cancer Cytopathol. 2022 Nov 18. doi: 10.1002/cncy.22664. Epub ahead of print.

• PMID: 36399410
• PubMed abstract

• Free Full Text

• Noninvasive Pregestational Genetic Testing of Embryos Using Smart Sensors Array.
• Abu Raya YS, Srebnik N, Rubinstein E, Schonberger O, Broza YY, Suschinel R, Haick H, Ionescu R.
• ACS Sens. 2022 Nov 14. doi: 10.1021/acssensors.2c01492. Epub ahead of print.

• PMID: 36374562
• PubMed abstract
• Source abstract

• Signal "on-off-off" strategy for improving the sensitivity of BRCA1 electrochemical detection by combining gold substrate amplification, DNA conformational transformation and DSN enzymatic hydrolysis dual reduction.
• Li Z, Chen J, Zhang L, Liu Y, Jia Y, Zhou G, Luo L.
• Anal Chim Acta. 2022 Dec 1;1235:340461. doi: 10.1016/j.aca.2022.340461. Epub 2022 Oct 1.

• PMID: 36368816
• PubMed abstract
• Source abstract

• Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing.
• Gunter HM, Youlten SE, Madala BS, Reis ALM, Stevanovski I, Wong T, Kummerfield SK, Deveson IW, Santini NS, Marcellin E, Mercer TR.
• Nat Commun. 2022 Oct 28;13(1):6437. doi: 10.1038/s41467-022-34028-8.

• PMID: 36307482
• PubMed abstract

• Free Full Text

• Electrochemical biosensors for analysis of DNA point mutations in cancer research.
• Ondraskova K, Sebuyoya R, Moranova L, Holcakova J, Vonka P, Hrstka R, Bartosik M.
• Anal Bioanal Chem. 2022 Oct 27. doi: 10.1007/s00216-022-04388-7. Epub ahead of print.

• PMID: 36289102
• PubMed abstract
• Source abstract

• Review

• Laboratory Cross-Comparison and Ring Test Trial for Tumor BRCA Testing in a Multicenter Epithelial Ovarian Cancer Series: The BORNEO GEICO 60-0 Study.
• Garcia-Casado Z, Oaknin A, Mendiola M, Alkorta-Aranburu G, Antunez-Lopez JR, Moreno-Bueno G, Palacios J, Yubero A, Marquez R, Gallego A, Sanchez-Heras AB, Lopez-Guerrero JA, Perez-Segura C, Barretina-Ginesta P, Alarcon J, Gaba L, Marquez A, Matito J, Cueva J, Palacio I, Iglesias M, Arcusa A, Sanchez-Lorenzo L, Guerra-Alia E, Romero I, Vivancos A.
• J Pers Med. 2022 Nov 4;12(11):1842. doi: 10.3390/jpm12111842.

• Source abstract

• Free Full Text

• Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2 or ATM Alterations Identified by Testing Circulating Tumor DNA.
• Matsubara N, de Bono J, Olmos D, Procopio G, Kawakami S, Ürün Y, van Alphen R, Flechon A, Carducci MA, Choi YD, Hotte SJ, Korbenfeld E, Kramer G, Agarwal N, Chi KN, Dearden S, Gresty C, Kang J, Poehlein C, Harrington EA, Hussain M.
• Clin Cancer Res. 2022 Nov 1:CCR-21-3577. doi: 10.1158/1078-0432.CCR-21-3577. Epub ahead of print.

• PMID: 36318705
• PubMed abstract
• Source abstract

• Free Full Text (PDF)

• Exquisitely Platinum-Sensitive Triple-Negative Breast Cancer, Time for BRCA Methylation Testing?
• Tan TJ, Fink JL, Tay TK, Jaradi B, Stone N, Waring P, Koo KM, Tan PH, Tan DS, Dent RA.
• JCO Precis Oncol. 2022 Nov;6:e2200309. doi: 10.1200/PO.22.00309.

• PMID: 36331241
• PubMed abstract
• Source abstract

• Case report