Category: Genetic Counseling

• Relatives from Hereditary Breast and Ovarian Cancer and Lynch Syndrome Families Forgoing Genetic Testing: Findings from the Swiss CASCADE Cohort.
• Sarki M, Ming C, Aceti M, Fink G, Aissaoui S, Bürki N, Graffeo R, Heinimann K, Zufferey MC, Monnerat C, Rabaglio M, Zürrer-Härdi U, Chappuis PO, Katapodi MC.
• J Pers Med. 2022 Oct 19;12(10):1740. doi: 10.3390/jpm12101740.

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• How should we address the inevitable harms from non-negligent variant reclassification in predictive genetic testing?
• Rashkin M, Kingham K, Lara-Otero , Mckenna M, Villiers J, Worthington MM, Prince A.
• J Genet Couns. 2022 Oct 19. doi: 10.1002/jgc4.1638. Epub ahead of print.

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• Germline Genetic Testing in Breast Cancer: Systemic Therapy Implications.
• Bhardwaj PV, Abdou YG.
• Curr Oncol Rep. 2022 Oct 18. doi: 10.1007/s11912-022-01340-x. Epub ahead of print.

• PMID: 36255604
• PubMed abstract
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• Review

• Clinical decisions by the molecular tumor board on comprehensive genomic profiling tests in Japan: A retrospective observational study.
• Shirota H, Komine K, Takahashi M, Takahashi S, Miyauchi E, Niizuma H, Tada H, Shimada M, Niihori T, Aoki Y, Sugiyama I, Kawamura M, Yasuda J, Suzuki S, Iwaya T, Saito M, Saito T, Shibata H, Furukawa T, Ishioka C.
• Cancer Med. 2022 Oct 17. doi: 10.1002/cam4.5349. Epub ahead of print.

• PMID: 36251535
• PubMed abstract
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• Proband-mediated interventions to increase disclosure of genetic risk in families with a BRCA or Lynch syndrome condition: a systematic review.
• Young AL, Imran A, Spoelma MJ, Williams R, Tucker KM, Halliday J, Forrest LE, Wakefield CE, Butow PN.
• Eur J Hum Genet. 2022 Oct 17. doi: 10.1038/s41431-022-01200-z. Epub ahead of print.

• PMID: 36253533
• PubMed abstract

• Review
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• An Accessible Communication System for Population-Based Genetic Testing: Development and Usability Study.
• Coffin T, Bowen D, Swisher E, Lu K, Rayes N, Norquist B, Blank S, Levine D, Bakkum-Gamez J, Fleming G, Olopade O, D'Andrea A, Nebgen D, Peterson C, Munsell M, Gavin K, Lechner R, Crase J, Polinsky D, Romero I.
• JMIR Form Res. 2022 Oct 17;6(10):e34055. doi: 10.2196/34055.

• PMID: 36251350
• PubMed abstract

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• Genetic Testing Challenges in Oncology: Missed Variant Update Delays Li-Fraumeni Diagnosis.
• Ray T.
• Precision Oncology News. 2022 Oct 12.

• Case report
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Related:

Special article:

Is there a duty to reinterpret genetic data? The ethical dimensions.

• PMID: 31616070
• PubMed abstract
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• Study: Teens and young adults respond well to learning about familial cancer risk
• [No author given]
• FORCE. XRAY. 2022 Oct 11.

• Research news
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Related:

Original research:

Long-Term Adaptation Among Adolescent and Young Adult Children to Familial Cancer Risk.

• PMID: 35859209
• PubMed abstract
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Commentary:

Breaking Down the Barriers of Hereditary Cancer Risk Disclosure in AYA.

• PMID: 35859132
• PubMed abstract
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• Validation of the modified Chinese Information and Support Needs Questionnaire (ISNQ-C) for daughters of mothers with breast cancer.
• Fang SY, Chen TC.
• Palliat Support Care. 2022 Oct 11:1-9. doi: 10.1017/S1478951522001407. Epub ahead of print.

• PMID: 36217687
• PubMed abstract
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• Barriers to completion of cascade genetic testing: how can we improve the uptake of testing for hereditary breast and ovarian cancer syndrome?
• Kahn RM, Ahsan MD, Chapman-Davis E, Holcomb K, Nitecki R, Rauh-Hain JA, Fowlkes RK, Tubito F, Pires M, Christos PJ, Tkachuk K, Krinsky H, Sharaf RN, Offit K, Lipkin S, Frey MK.
• Fam Cancer. 2022 Oct 8. doi: 10.1007/s10689-022-00316-x. Epub ahead of print.

• PMID: 36207653
• PubMed abstract
• Source abstract