Author: Steve Kopczak

• Abiraterone/Olaparib Benefit Is Sustained in Final OS Analysis for mCRPC.
• Clarke NW, Lovely B.
• OncLive. 2023 Feb 16.

• Conference report
• Free Full Text

Related:

•• Identifier: NCT03732820: Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer. (ClinicalTrials.gov . Accessed 2023 Feb 16.)

• Analysis of BRCA1 and BRCA2 alternative splicing in predisposition to ovarian cancer.
• Jasiak A, Koczkowska M, Stukan M, Wydra D, Biernat W, Izycka-Swieszewska E, Buczkowski K, Eccles MR, Walker L, Wasag B, Ratajska M.
• Exp Mol Pathol. 2023 Feb 13:104856. doi: 10.1016/j.yexmp.2023.104856. Epub ahead of print.

• PMID: 36791903
• PubMed abstract

• Prostate cancer and novel pharmacological treatment options - what's new for 2022?
• Marchetti A, Tassinari E, Rosellini M, Rizzo A, Massari F, Mollica V.
• Expert Rev Clin Pharmacol. 2023 Feb 15. doi: 10.1080/17512433.2023.2181783. Epub ahead of print.

• PMID: 36794353
• PubMed abstract
• Source abstract

• Review

• Uptake and Effectiveness of Risk-Reducing Surgeries in Unaffected Female BRCA1 and BRCA2 Carriers: A Single Institution Experience in the Czech Republic.
• Zimovjanova M, Bielcikova Z, Miskovicova M, Vocka M, Zimovjanova A, Marian Rybar M, Novotny J, Petruzelka L.
• Cancers (Basel). 2023 Feb 8;15(4):1072. doi: 10.3390/cancers15041072.

• Free Full Text

• Hereditary Cancer Syndrome in a Family with Double Mutation in BRIP1 and MUTYH Genes.
• D’Elia G, Caliendo G, Passariello L, Albanese L, Makker J, Molinari AM, Vietri MT.
• Genes (Basel). 2023 Feb 8;14(2):428. doi: 10.3390/genes14020428.

• Case report
• Free Full Text

• Multiple synchronous malignancies in an infant with concomitant homozygous BRCA2 and PMS2 mutations with Fanconi anemia phenotype.
• Alghanim HM, Eltawel M, Alhaidari AI, Alobaid MM, Moghairi AM, Sufiani F, Ahmad N.
• Pediatr Hematol Oncol. 2023 Feb 2:1-8. doi: 10.1080/08880018.2022.2154417. Epub ahead of print.

• PMID: 36731423
• PubMed abstract
• Source abstract

• Case report

• BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
• Wu B, Qi L, Chiang HC, Pan H, Zhang X, Greenbaum A, Stark E, Wang LJ, Chen Y, Haddad BR, Clagett D, Isaacs C, Elledge R, Horvath A, Hu Y, Li R.
• J Immunother Cancer. 2023 Feb;11(2):e005852. doi: 10.1136/jitc-2022-005852.

• PMID: 36731891
• PubMed abstract

• Free PMC article
• Free Full Text

• Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA.
• Yoon JK, Ahn J, Kim S, Kim HP, Kang JK, Bang D, Lim Y, Kim TY.
• Cancer Res Treat. 2023 Jan 31. doi: 10.4143/crt.2022.1529. Epub ahead of print.

• PMID: 36731462
• PubMed abstract
• Source abstract

• Case report
• Free Full Text (PDF)

• Systemic Therapies for Metastatic Castration-Resistant Prostate Cancer: An Updated Review.
• Hatano K, Nonomura N.
• World J Mens Health. 2023 Jan 27. doi: 10.5534/wjmh.220200. Epub ahead of print.

• PMID: 36792090
• PubMed abstract
• Source abstract

• Review
• Free Full Text

• Association of Reported Candidate Monogenic Genes With Lung Cancer Risk.
• Rifkin AS, Less EM, Wei J, Shi Z, Zheng SL, Helfand BT, Hulick PJ, Krantz SB, Xu J.
• Clin Lung Cancer. 2023 Jan 26:S1525-7304(23)00009-8. doi: 10.1016/j.cllc.2023.01.005. Epub ahead of print.

• PMID: 36767056
• PubMed abstract

• Free Full Text