- Clinical Application of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Prostate Cancer.
- Inderjeeth AJ, Topp M, Sanij E, Castro E, Sandhu S.
- Cancers (Basel). 2022 Nov 30;14(23):5922. doi: 10.3390/cancers14235922.
- Review
- Free Full Text
- Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer.
- Trendowski MR, Sample C, Baird T, Sadeghpour A, Moon D, Ruterbusch JJ, Beebe-Dimmer JL, Cooney KA.
- JCO Precis Oncol. 2022 Nov [2022 Nov 29];6:e2200460. doi: 10.1200/PO.22.00460.
- PMID: 36446039
- PubMed abstract
- Source abstract
•• Research news: Genetic Variants Linked to Prostate Cancer in Black Men Identified. (Inside Precision Medicine)
- Analyzing the effects of BRCA1/2 variants on mRNA splicing by minigene assay.
- Dong Z, Wang Y, Zhang J, Zhu F, Liu Z, Kang Y, Lin M, Shi H.
- J Hum Genet. 2022 Nov 29. doi: 10.1038/s10038-022-01077-2. Epub ahead of print.
- PMID: 36446827
- PubMed abstract
- Clinical and psychological implications of secondary and incidental findings in cancer susceptibility genes after exome sequencing in patients with rare disorders.
- Carrasco E, López-Fernández A, Codina-Sola M, Valenzuela I, Cueto-González AM, Villacampa G, Navarro V, Torres-Esquius S, Palau D, Cruellas M, Torres M, Perez-Dueñas B, Abulí A, Diez O, Sábado-Álvarez C, García-Arumí E, Tizzano EF, Moreno L, Balmaña J.
- J Med Genet. 2022 Nov 29:jmg-2022-108929. doi: 10.1136/jmg-2022-108929. Epub ahead of print.
- PMID: 36446584
- PubMed abstract
- Source abstract
- Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases.
- Duchnowska R, Supernat AM, Pęksa R, Łukasiewicz M, Stokowy T, Ronen R, Dutkowski J, Umińska M, Iżycka-Świeszewska E, Kowalczyk A, Och W, Rucińska M, Olszewski WP, Mandat T, Jarosz B, Bieńkowski M, Biernat W, Jassem J.
- Sci Rep. 2022 Nov 29;12(1):20537. doi: 10.1038/s41598-022-23788-4.
- PMID: 36446793
- PubMed abstract
- [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a pilot study.
- Pantel AR, Gitto SB, Makvandi M, Kim H, Medvedv S, Weeks JK, Torigian DA, Hsieh CJ, Ferman B, Latif NA, Tanyi JL, Martin LP, Lanzo SM, Liu F, Cao Q, Mills GB, Doot RK, Mankoff DA, Mach RH, Lin LL, Simpkins F.
- Clin Cancer Res. 2022 Nov 28:CCR-22-1602. doi: 10.1158/1078-0432.CCR-22-1602. Epub ahead of print.
- PMID: 36441795
- PubMed abstract
- Source abstract
- Adolescent triple-negative breast cancer with germline pathogenic variants in both BRCA1 and TP53 genes: A case report.
- Chen D, Zhang C, Yuan M, Zhang Y, Liu Q, Wan D.
- Front Oncol. 2022 Nov 28;12:970641. doi: 10.3389/fonc.2022.970641.
- Case report
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- Halo Diagnostics, Ikonopedia Partner to Provide Genetic Testing for Breast Cancer.
- [No author given]
- Precision Oncology News. 2022 Nov 28.
- News
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- Long-term response to olaparib in a patient with metastatic pancreatic cancer associated with hereditary breast and ovarian cancer syndrome.
- Tsuneizumi M, Terada S, Usui T, Yamaguchi K, Hayami R, Matsunuma R.
- Oxf Med Case Reports. 2022 Nov 24;2022(11):omac124. doi: 10.1093/omcr/omac124.
- PMID: 36447463
- PubMed abstract
- Case report
- Free PMC article
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