Quality of Life ~ Risk-Reducing Salpingo-Oophorectomy
~ Genetics of Breast & Ovarian Cancer

List was last updated on Oct 10, 2019 @ 2:29 pm.


    • Interventions to improve psychosocial well-being in female BRCA-mutation carriers following risk-reducing surgery.
    • Jeffers L, Reid J, Fitzsimons D, Morrison PJ, Dempster M.
    • Cochrane Database Syst Rev. 2019 Oct 9;10:CD012894. doi: 10.1002/14651858.CD012894.pub2. [Epub ahead of print]
    • Review

    Original research:

    Mindfulness-based stress reduction for menopausal symptoms after risk-reducing salpingo-oophorectomy (PURSUE study): a randomised controlled trial.

    Original research:

    Addressing sexual dysfunction after risk-reducing salpingo-oophorectomy: effects of a brief, psychosexual intervention.

    • How Safe Is Hormone Replacement Therapy After Risk-Reducing Salpingo-oophorectomy in Women With BRCA Mutations?
    • Markman M.
    • Medscape Oncology. 2019 Jun 14.

    Original research:

    Hormone replacement therapy after risk reducing salpingo-oophorectomy in patients with BRCA1 or BRCA2 mutations; a systematic review of risks and benefits.

    • Long-term morbidity and health after early menopause due to oophorectomy in women at increased risk of ovarian cancer: rationale and design of the harmony study.
    • Terra L, Hooning MJ, Heemskerk-Gerritsen BAM, Maas AHEM, van Leeuwen FE, HARMOny investigators.
    • Maturitas. 2019 Jun;124:159-160. doi: 10.1016/j.maturitas.2019.04.136.
    • Conference abstract, Review
    • Hormone replacement therapy after risk reducing salpingo-oophorectomy in patients with BRCA1 or BRCA2 mutations; a systematic review of risks and benefits.
    • Gordhandas S, Norquist BM, Pennington KP, Yung RL, Laya MB, Swisher EM.
    • Gynecol Oncol. 2019 Apr;153(1):192-200. doi: 10.1016/j.ygyno.2018.12.014. Epub 2019 Jan 17.
    • Review

    Commentary: How Safe Is Hormone Replacement Therapy After Risk-Reducing Salpingo-oophorectomy in Women With BRCA Mutations? (Medscape Oncology)

    • Surgery to Reduce Ovarian Cancer Risk — One Step or Two?
    • Harrison P
    • Medscape. Medscape Oncology. 2019 Mar 25.
    • Concerns and Expectations of Risk-Reducing Surgery in Women with Hereditary Breast and Ovarian Cancer Syndrome.
    • Modaffari P, Ponzone R, Ferrari A, Cipullo I, Liberale V, D'Alonzo M, Maggiorotto F, Biglia N.
    • J Clin Med. 2019 Mar 5;8(3). pii: E313. doi: 10.3390/jcm8030313.
    • Mindfulness-based stress reduction for menopausal symptoms after risk-reducing salpingo-oophorectomy (PURSUE study): a randomised controlled trial.
    • van Driel C, de Bock GH, Schroevers MJ, Mourits MJ.
    • BJOG. 2019 Feb;126(3):402-411. doi: 10.1111/1471-0528.15471. Epub 2018 Oct 23.

    Review:

    Interventions to improve psychosocial well-being in female BRCA-mutation carriers following risk-reducing surgery.

    • Risk factors for sexual dysfunction in BRCA mutation carriers after risk-reducing salpingo-oophorectomy.
    • Chan JL, Senapati S, Johnson LNC, DiGiovanni L, Voong C, Butts SF, Domchek SM.
    • Menopause. 2019 Feb;26(2):132-139. doi: 10.1097/GME.0000000000001176.
    • Effects of bilateral salpingo-oophorectomy on menopausal symptoms and sexual functioning among women with a BRCA1 or BRCA2 mutation.
    • Hall E, Finch A, Jacobson M, Rosen B, Metcalfe K, Sun P, Narod SA, Kotsopoulos J.
    • Gynecol Oncol. 2019 Jan;152(1):145-150. doi: 10.1016/j.ygyno.2018.10.040. Epub 2018 Nov 7.
    • Does anti-Müllerian hormone predict change in menopausal symptoms following risk-reducing salpingo-oophorectomy? A prospective observational study.
    • Vermeulen RFM, van Beurden M, Gaarenstroom KN, Teunis T, Kieffer JM, Aaronson NK, Kenter GG, Korse CM.
    • Climacteric. 2018 Dec;21(6):574-580. doi: 10.1080/13697137.2018.1512965. Epub 2018 Oct 8.
    • Satisfaction and Impact on Quality of Life of Clinical and Instrumental Surveillance and Prophylactic Surgery in BRCA-mutation Carriers.
    • D'Alonzo M, Piva E, Pecchio S, Liberale V, Modaffari P, Ponzone R, Biglia N.
    • Clin Breast Cancer. 2018 Dec;18(6):e1361-e1366. doi: 10.1016/j.clbc.2018.07.015. Epub 2018 Jul 26.
    • Adaptation of couples living with a high risk of breast/ovarian cancer and the association with risk-reducing surgery.
    • Shapira R, Turbitt E, Erby LH, Biesecker BB, Klein WMP3, Hooker GW.
    • Fam Cancer. 2018 Oct;17(4):485-493. doi: 10.1007/s10689-017-0065-z.
    • Surgical prevention strategies in ovarian cancer.
    • Mallen A, Soong TR, Townsend MK, Wenham RM, Crum CP, Tworoger SS.
    • Gynecol Oncol. 2018 Oct;151(1):166-175. doi: 10.1016/j.ygyno.2018.08.005. Epub 2018 Aug 4.
    • Review
    • Surgery for BRCA, TP53 and PALB2: a literature review.
    • Song CV, Teo SH, Taib NA, Yip CH.
    • Ecancermedicalscience. 2018 Aug 29;12:863. doi: 10.3332/ecancer.2018.863. eCollection 2018.
    • Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations.
    • Eleje GU, Eke AC, Ezebialu IU, Ikechebelu JI, Ugwu EO, Okonkwo OO.
    • Cochrane Database Syst Rev. 2018 Aug 24;8:CD012464. doi: 10.1002/14651858.CD012464.pub2.
    • Meta-Analysis, Review
    • Bilateral salpingectomy with delayed oophorectomy for ovarian cancer risk reduction: A pilot study in women with BRCA1/2 mutations.
    • Nebgen DR, Hurteau J, Holman LL, Bradford A, Munsell MF, Soletsky BR, Sun CC, Chisholm GB, Lu KH.
    • Gynecol Oncol. 2018 Jul;150(1):79-84. doi: 10.1016/j.ygyno.2018.04.564. Epub 2018 May 4.
    • Hormone Levels and Sexual Functioning After Risk-Reducing Salpingo-Oophorectomy.
    • Johansen N, Liavaag AH, Mørkrid L, Michelsen TM.
    • Sex Med. 2018 Jun;6(2):143-153. doi: 10.1016/j.esxm.2018.02.002. Epub 2018 Apr 7.
    • Severity and duration of menopausal symptoms after risk-reducing salpingo-oophorectomy.
    • Stuursma A, van Driel CMG, Wessels NJ, de Bock GH, Mourits MJE.
    • Maturitas. 2018 May;111:69-76. doi: 10.1016/j.maturitas.2018.01.012. Epub 2018 Jan 13.
    • A12 Quality of life of BRCA1 carriers after preventive adnexectomy.
    • Sawicka J, Jasiewicz A, Gronwald J.
    • Hered Cancer Clin Pract. 2018 Feb 28;16(Suppl 1):A12. Meeting abstracts from Clinical Genetics of Cancer 2017; Szczecin, Poland. 21-22 September 2017. doi: 10.1186/s13053-018-0087-z.
    • Conference abstract
    • Self-compassion, physical fitness and climacteric symptoms in oophorectomized BRCA1/2 mutation carriers.
    • Arts-de Jong M, van Westerop LL, Hoogerbrugge N, Massuger LF, Maas AH, van Beek MH, de Hullu JA.
    • Maturitas. 2018 Feb;108:13-17. doi: 10.1016/j.maturitas.2017.11.002. Epub 2017 Nov 3.
    • Severity and duration of menopausal symptoms after risk-reducing salpingo-oophorectomy.
    • Stuursma A, van Driel CMG, Wessels NJ, de Bock GH, Mourits MJE.
    • Maturitas. 2018 Jan 12. pii: S0378-5122(17)30950-7. doi: 10.1016/j.maturitas.2018.01.012. [Epub ahead of print]

    Press: Menopausal Symptoms May Last Over 10 Years After Risk-reducing Ovarian Surgery. (Medscape/Reuters)

    • Quality-of-life implications of risk-reducing cancer surgery.
    • Altman AM, Hui JYC, Tuttle TM.
    • Br J Surg. 2018 Jan;105(2):e121-e130. doi: 10.1002/bjs.10725.
    • Genetics of Breast and Gynecologic Cancers (PDQ®): Health Professional Version. Psychosocial Issues in Inherited Breast and Ovarian Cancer Syndromes. Psychosocial Outcome Studies.
    • PDQ Cancer Genetics Editorial Board.
    • PDQ Cancer Information Summaries [Internet]. Bethesda, MD: National Cancer Institute. Updated 2017 Nov 30. Accessed 2017 Dec 8.
    • What Happens After Menopause? (WHAM): protocol for a prospective, multicentre, age-matched cohort trial of risk-reducing bilateral salpingo-oophorectomy in high-risk premenopausal women.
    • Hickey M, Trainer A, Braat S, Davey MA, Krejany E, Wark J.
    • BMJ Open. 2017 Nov 14;7(11):e018758. doi: 10.1136/bmjopen-2017-018758.
    • Sexual Health Is Paramount in the Counseling of Women at Risk for Breast or Ovarian Cancer Undergoing Risk-Reducing Surgery.
    • Rullo JE, Pruthi S.
    • J Natl Compr Canc Netw. 2017 Nov 1;15(11):1297. doi: 10.6004/jnccn.2017.7016.
    • Commentary
    • [Satisfaction and overall quality of life in BRCA positive women after prophylactic surgeries].
    • Šašková P, Pavlišta D, Dostálek L.
    • Rozhl Chir. 2017 Fall;96(8):328-333.
    • Review, [Article in Czech]
    • Impact of risk-reducing salpingo-oophorectomy in premenopausal women.
    • Vermeulen RFM, Beurden MV, Korse CM, Kenter GG.
    • Climacteric. 2017 Jun;20(3):212-221. doi: 10.1080/13697137.2017.1285879. Epub 2017 Mar 2.
    • Use of hormone replacement therapy after risk-reducing salpingo-oophorectomy.
    • Johansen N, Liavaag AH, Iversen OE, Dørum A, Braaten T, Michelsen TM.
    • Acta Obstet Gynecol Scand. 2017 May;96(5):547-555. doi: 10.1111/aogs.13120. Epub 2017 Mar 27.
    • Review Article: Sexuality and Risk-Reducing Salpingo-oophorectomy.
    • Tucker PE, Cohen PA.
    • Int J Gynecol Cancer. 2017 May;27(4):847-852. doi: 10.1097/IGC.0000000000000943.
    • Review
    • Risk-Reducing Strategies for Ovarian Cancer in BRCA Mutation Carriers: A Balancing Act.
    • Tschernichovsky R, Goodman A.
    • Oncologist. 2017 Apr;22(4):450-459. doi: 10.1634/theoncologist.2016-0444. Epub 2017 Mar 17.
    • The effect of hormone therapy on quality of life and breast cancer risk after risk-reducing salpingo-oophorectomy: a systematic review.
    • Siyam T, Ross S, Campbell S, Eurich DT, Yuksel N.
    • BMC Womens Health. 2017 Mar 21;17(1):22. doi: 10.1186/s12905-017-0370-6.
    • High demoralization in a minority of oophorectomized BRCA1/2 mutation carriers influences quality of life.
    • Arts-de Jong M, DeJong CA, Hermens RP, Kissane DW, Massuger LM, Hoogerbrugge N, Prins JB, deHullu JA.
    • J Psychosom Obstet Gynaecol. 2017 Mar 10:1-9. doi: 10.1080/0167482X.2017.1296429. [Epub ahead of print]
    • Sexuality and quality of life in women with a prior diagnosis of breast cancer after risk-reducing salpingo-oophorectomy.
    • Tucker PE, Saunders C, Bulsara MK, Tan JJ, Salfinger SG, Green H, Cohen PA.
    • Breast. 2016 Dec;30:26-31. doi: 10.1016/j.breast.2016.08.005. Epub 2016 Sep 2.
    • Study on the psychosocial aspects of risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 mutation carriers in Japan: a preliminary report.
    • Shigehiro M, Kita M, Takeuchi S, Ashihara Y, Arai M, Okamura H.
    • Jpn J Clin Oncol. 2016 Mar;46(3):254-9. doi: 10.1093/jjco/hyv190. Epub 2015 Dec 18.
    • The effects of pre-operative menopausal status and hormone replacement therapy (HRT) on sexuality and quality of life after risk-reducing salpingo-oophorectomy.
    • Tucker PE, Bulsara MK, Salfinger SG, Tan JJ, Green H, Cohen PA.
    • Maturitas. 2016 Mar;85:42-8. doi: 10.1016/j.maturitas.2015.12.004. Epub 2015 Dec 12.
    • Prevalence of sexual dysfunction after risk-reducing salpingo-oophorectomy.
    • Tucker PE, Bulsara MK, Salfinger SG, Tan JJ, Green H, Cohen PA.
    • Gynecol Oncol. 2016 Jan;140(1):95-100. doi: 10.1016/j.ygyno.2015.11.002. Epub 2015 Nov 3.
    • Sexual activity and functioning after risk-reducing salpingo-oophorectomy: Impact of hormone replacement therapy.
    • Johansen N, Liavaag AH, Tanbo TG, Dahl AA, Pripp AH, Michelsen TM.
    • Gynecol Oncol. 2016 Jan;140(1):101-106. doi: 10.1016/j.ygyno.2015.11.016. Epub 2015 Nov 18.
    • Laparoendoscopic Single-site Surgery (LESS) for Prophylactic Salpingo-oophorectomy Improves Cosmetic Satisfaction Compared to Standard Laparoscopy.
    • Miailhe G, Dauchy S, Bentivegna E, Gouy S, Charles C, Delaloge S, Morice P, Uzan C.
    • Anticancer Res. 2015 Nov;35(11):6105-10.
    • Early salpingectomy (TUbectomy) with delayed oophorectomy to improve quality of life as alternative for risk-reducing salpingo-oophorectomy in BRCA1/2 mutation carriers (TUBA study): a prospective non-randomised multicentre study.
    • Harmsen MG, Arts-de Jong M, Hoogerbrugge N, Maas AH, Prins JB, Bulten J, Teerenstra S, Adang EM, Piek JM, van Doorn HC, van Beurden M, Mourits MJ, Zweemer RP, Gaarenstroom KN, Slangen BF, Vos MC, van Lonkhuijzen LR, Massuger LF, Hermens RP, de Hullu JA.
    • BMC Cancer. 2015 Aug 19;15(1):593. doi: 10.1186/s12885-015-1597-y.
    • Weight gain after oophorectomy among women with a BRCA1 or BRCA2 mutation.
    • Kotsopoulos J, Lubinski J, Neuhausen SL, Gronwald J, Lynch HT, Huzarski T, Demsky R, Foulkes WD, Senter L, Friedman S, Ainsworth P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Womens Health (Lond Engl). 2015 Jul;11(4):453-9. doi: 10.2217/WHE.15.4. Epub 2015 Aug 10.
    • Long-term outcomes of risk-reducing surgery in unaffected women at increased familial risk of breast and/or ovarian cancer.
    • Heiniger L, Butow PN, Coll J, Bullen T, Wilson J, Baylock B, Meiser B, Price MA.
    • Fam Cancer. 2015 Mar;14(1):105-15. doi: 10.1007/s10689-014-9759-7.
    • Addressing sexual dysfunction after risk-reducing salpingo-oophorectomy: effects of a brief, psychosexual intervention.
    • Bober SL, Recklitis CJ, Bakan J, Garber JE, Patenaude AF.
    • J Sex Med. 2015 Jan;12(1):189-97. doi: 10.1111/jsm.12713. Epub 2014 Oct 14.

    Review:

    Interventions to improve psychosocial well-being in female BRCA-mutation carriers following risk-reducing surgery.

    • Relationship satisfaction predicts sexual activity following risk-reducing salpingo-oophorectomy.
    • Lorenz T, McGregor B, Swisher E.
    • J Psychosom Obstet Gynaecol. 2014 Jun;35(2):62-8. doi: 10.3109/0167482X.2014.899577. Epub 2014 Apr 3.
    • Long-term satisfaction and quality of life following risk reducing surgery in BRCA1/2 mutation carriers.
    • Hooker GW, King L, Vanhusen L, Graves K, Peshkin BN, Isaacs C, Taylor KL, Poggi E, Schwartz MD.
    • Hered Cancer Clin Pract. 2014 Apr 2;12(1):9. doi: 10.1186/1897-4287-12-9.
    • Oophorectomy can reduce ovarian cancer risk in women with BRCA mutations: Patients benefit from counseling, support.
    • Printz C.
    • Cancer. 2013 Nov 15;119(22):3897-8. doi: 10.1002/cncr.28455.
    • Body Image and Sexuality After Surgery, Cancer and/or Treatment, for Survivors and Previvors.
    • Sharon Bober
    • FORCE. Be Empowered Webinars. 2013 Aug 28.
    • Association of bilateral oophorectomy and body fatness in a representative sample of US women.
    • McCarthy AM, Menke A, Visvanathan K.
    • Gynecol Oncol. 2013 Jun;129(3):559-64. doi: 10.1016/j.ygyno.2013.02.016. Epub 2013 Feb 18.
    • Prophylactic Salpingectomy and Delayed Oophorectomy as an Alternative for BRCA Mutation Carriers.
    • Kwon JS, Tinker A, Pansegrau G, McAlpine J, Housty M, McCullum M, Gilks CB.
    • Obstet Gynecol. 2013 Jan;121(1):14-24. doi: http://10.1097/AOG.0b013e3182783c2f.

    Editorial/Comment:

    Ideal Risk Reduction Management for Women With BRCA Gene Mutations: Still Not There Yet.

    • The impact of prophylactic salpingo-oophorectomy on quality of life and psychological distress in women with a BRCA mutation.
    • Finch A, Metcalfe KA, Chiang J, Elit L, McLaughlin J, Springate C, Esplen MJ, Demsky R, Murphy J, Rosen B, Narod SA.
    • Psychooncology. 2013 Jan;22(1):212-9. doi: 10.1002/pon.2041. Epub 2011 Sep 13.
    • BRCA carriers, prophylactic salpingo-oophorectomy and menopause: clinical management considerations and recommendations.
    • Finch A, Evans G, Narod SA.
    • Womens Health (Lond Engl). 2012 Sep;8(5):543-55. doi: 10.2217/whe.12.41.

    Free text: BRCA Carriers, Prophylactic Salpingo-Oophorectomy and Menopause: Clinical Management Considerations and Recommendations (Medscape)

    • New findings presented on metastatic breast cancer and bilateral oophorectomy.
    • Printz C.
    • Cancer. 2012 Jun 1;118(11):2778. doi: 10.1002/cncr.27643.
    • Looking different, feeling different: women's reactions to risk-reducing breast and ovarian surgery.
    • Hallowell N, Baylock B, Heiniger L, Butow PN, Patel D, Meiser B, Saunders C; kConFab Psychosocial Group on behalf of the kConFab Investigators, Price MA.
    • Fam Cancer. 2012 Jun;11(2):215-24. doi: 10.1007/s10689-011-9504-4.
    • Non-cancer endpoints in BRCA1/2 carriers after risk-reducing salpingo-oophorectomy.
    • Cohen JV, Chiel L, Boghossian L, Jones M, Stopfer JE, Powers J, Rebbeck TR, Nathanson KL, Domchek SM.
    • Fam Cancer. 2012 Mar;11(1):69-75. doi: 10.1007/s10689-011-9480-8.
    • Risk-reducing bilateral salpingo-oophorectomy and sexual health: a qualitative study.
    • Brotto LA, Branco N, Dunkley C, McCullum M, McAlpine JN.
    • J Obstet Gynaecol Can. 2012 Feb;34(2):172-8.