Pregnancy and HBOC ~ Management
~ Genetics of Breast & Ovarian Cancer

List was last updated on Apr 20, 2021 @ 12:48 am.


    • Controversies in Hereditary Cancer Management.
    • AlHilli MM, Pederson HJ.
    • Obstet Gynecol. 2021 Apr 8. doi: 10.1097/AOG.0000000000004364. Epub ahead of print.
    • Fertility treatments and breast cancer risk in Jewish Israeli BRCA mutation carriers.
    • Perri T, Naor-Revel S, Eliassi-Revivo P, Lifshitz D, Friedman E, Korach J.
    • Fertil Steril. 2021 Apr 3:S0015-0282(21)00148-5. doi: 10.1016/j.fertnstert.2021.02.030. Epub ahead of print.
    • Fertility preservation in patients with BRCA mutations or Lynch syndrome.
    • Corrado G, Marchetti C, Trozzi R, Scambia G, Fagotti A.
    • Int J Gynecol Cancer. 2021 Mar;31(3):332-338. doi: 10.1136/ijgc-2020-002071.
    • Study: Breastfeeding may lower risk of ovarian cancer in women with BRCA mutations.
    • [No author given]
    • FORCE. XRAY. 2021 Jan 28.

    Related:

    Original research:

    Hereditary Ovarian Cancer Clinical Study Group. Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation.

    • Sichere Schwangerschaft nach Brustkrebstherapie von BRCA-Mutations-Trägerinnen? [Safe pregnancy after breast cancer treatment in patients carrying BRCA mutations?].
    • Souchon R.
    • Strahlenther Onkol. 2020 Dec 11. German. doi: 10.1007/s00066-020-01726-5. Epub ahead of print.
    • Commentary, [Article in German]
    • Impact of ARTs on oncological outcomes in young breast cancer survivors.
    • Condorelli M, De Vos M, Lie Fong S, Autin C, Delvigne A, Vanden Meerschaut F, Wyns C, Imbert R, Cheruy C, Bouziotis J, de Azambuja E, Delbaere A, Lambertini M, Demeestere I.
    • Hum Reprod. 2020 Dec 8:deaa319. doi: 10.1093/humrep/deaa319. Epub ahead of print.
    • Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines†.
    • Lambertini M, Peccatori FA, Demeestere I, Amant F, Wyns C, Stukenborg JB, Paluch-Shimon S, Halaska MJ, Uzan C, Meissner J, von Wolff M, Anderson RA, Jordan K; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org.
    • Ann Oncol. 2020 Dec;31(12):1664-1678. doi: 10.1016/j.annonc.2020.09.006. Epub 2020 Sep 22.
    • Fertility in BRCA mutation carriers: counseling BRCA-mutated patients on reproductive issues.
    • Knabben L, Siegenthaler F, Imboden S, Mueller MD.
    • Horm Mol Biol Clin Investig. 2020 Oct 6. doi: 10.1515/hmbci-2020-0005. Epub ahead of print.
    • Review
    • Young women's decision-making and experience of using tamoxifen to reduce BRCA1/2 breast cancer risk: a qualitative study.
    • Forrest LE, Shepherd RF, Young MA, Keogh LA, James PA.
    • Psychooncology. 2020 Oct 1. doi: 10.1002/pon.5556. Epub ahead of print.
    • Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation.
    • Kotsopoulos J, Gronwald J, McCuaig JM, Karlan BY, Eisen A, Tung N, Bordeleau L, Senter L, Eng C, Couch F, Fruscio R, Weitzel JN, Olopade O, Singer CF, Pal T, Foulkes WD, Neuhausen SL, Sun P, Lubinski J, Narod SA, the Hereditary Ovarian Cancer Clinical Study Group.
    • Gynecol Oncol. 2020 Sep 30:S0090-8258(20)33947-0. doi: 10.1016/j.ygyno.2020.09.037. Epub ahead of print.
    • Integrative Review of Reproductive Decision Making of Women Who Are BRCA Positive.
    • Skrovanek E, Dunbar-Jacob J, Dunwoody C, Wesmiller S.
    • J Obstet Gynecol Neonatal Nurs. 2020 Sep 11:S0884-2175(20)30117-9. doi: 10.1016/j.jogn.2020.07.006. Epub ahead of print.
    • Review
    • Burning Questions in the Oncofertility Counseling of Young Breast Cancer Patients.
    • Arecco L, Perachino M, Damassi A, Latocca MM, Soldato D, Vallome G, Parisi F, Razeti MG, Solinas C, Tagliamento M, Spinaci S, Massarotti C, Lambertini M.
    • Breast Cancer (Auckl). 2020 Sep 4;14:1178223420954179. doi: 10.1177/1178223420954179.
    • Reproductive decision-making in the context of hereditary cancer: the effects of an online decision aid on informed decision-making.
    • Reumkens K, Tummers MHE, Severijns Y, Gietel-Habets JJG, van Kuijk SMJ, Aalfs CM, van Asperen CJ, Ausems MGEM, Collée M, Dommering CJ, Kets M, van der Kolk LE, Oosterwijk JC, Tjan-Heijnen VCG, van der Weijden T, de Die-Smulders CEM, van Osch LADM.
    • J Community Genet. 2020 Sep 2. doi: 10.1007/s12687-020-00484-2. Epub ahead of print.
    • BRCA1/2 genes mutations, ovarian reserve and female reproductive outcomes: a systematic literature review.
    • Merlino L, Chiné A, Galli C, Piccioni MG.
    • Minerva Ginecol. 2020 Aug 3. doi: 10.23736/S0026-4784.20.04624-9. Epub ahead of print.
    • Review
    • Use of fertility treatments in BRCA1/2 mutation carriers and risk for ovarian and breast cancer: a systematic review.
    • Huber D, Seitz S, Kast K, Emons G, Ortmann O.
    • Arch Gynecol Obstet. 2020 Jul 27. doi: 10.1007/s00404-020-05690-4. Epub ahead of print.
    • Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations.
    • Lambertini M, Ameye L, Hamy AS, Zingarello A, Poorvu PD, Carrasco E, Grinshpun A, Han S, Rousset-Jablonski C, Ferrari A, Paluch-Shimon S, Cortesi L, Senechal C, Miolo G, Pogoda K, Pérez-Fidalgo JA, De Marchis L, Ponzone R, Livraghi L, Estevez-Diz MDP, Villarreal-Garza C, Dieci MV, Clatot F, Berlière M, Graffeo R, Teixeira L, Córdoba O, Sonnenblick A, Luna Pais H, Ignatiadis M, Paesmans M, Partridge AH, Caron O, Saule C, Del Mastro L, Peccatori FA, Azim HA Jr.
    • J Clin Oncol. 2020 Jul 16:JCO1902399. doi: 10.1200/JCO.19.02399. Epub ahead of print.
    • Management of breast cancer risk in BRCA1/2 mutation carriers who are unaffected with cancer.
    • Collins JM, Isaacs C.
    • Breast J. 2020 Jul 11. doi: 10.1111/tbj.13970. Epub ahead of print.
    • Review
    • Effects of BRCA gene mutation on female reproductive potential: A systematic review.
    • Hu KL, Wang S, Ye X, Zhang D.
    • Maturitas. 2020 Jul;137:11-17. doi: 10.1016/j.maturitas.2020.04.011. Epub 2020 Apr 23.
    • Review
    • Executive Summary of the Early-Onset Breast Cancer Evidence Review Conference.
    • Chelmow D, Pearlman MD, Young A, Bozzuto L, Dayaratna S, Jeudy M, Kremer ME, Scott DM, O'Hara JS.
    • Obstet Gynecol. 2020 Jun;135(6):1457-1478. doi: 10.1097/AOG.0000000000003889.
    • BRCA and Motherhood: A Matter of Time and Timing.
    • Possick C, Kestler-Peleg M.
    • Qual Health Res. 2019 Dec 7:1049732319885113. doi: 10.1177/1049732319885113. [Epub ahead of print]
    • The contribution of breastfeeding to the prevention of breast cancer.
    • Dimou S, Mamakou A, Konstantaki E, Spanou M.
    • Eur J Midwifery. 2019 Nov 29;3:21. doi: 10.18332/ejm/114885.
    • Contraception options for patients with known hereditary risk for ovarian cancer.
    • Joy KM.
    • JAAPA. 2019 Nov;32(11):37-41. doi: 10.1097/01.JAA.0000586384.47435.31.
    • Review
    • Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review.
    • Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T.
    • Fertil Steril. 2019 Oct 3. pii: S0015-0282(19)31982-X. doi: 10.1016/j.fertnstert.2019.07.1349. [Epub ahead of print]
    • Review
    • Is it safe for BRCA mutation carriers to become pregnant following breast cancer?
    • [No author given]
    • FORCE. XRAYS. 2019 Sep 4.
    • Pregnancy-associated breast cancer in a contemporary cohort of newly diagnosed women.
    • Gooch JC, Chun J, Kaplowitz E, Guth A, Axelrod D, Shapiro R, Roses D, Schnabel F.
    • Breast J. 2019 Aug 25. doi: 10.1111/tbj.13510. [Epub ahead of print]
    • Reproductive and Hormonal Considerations in Women at Increased Risk for Hereditary Gynecologic Cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review.
    • Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T.
    • Gynecol Oncol. 2019 Aug 22. pii: S0090-8258(19)31333-2. doi: 10.1016/j.ygyno.2019.06.017. [Epub ahead of print]
    • Review
    • The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With BRCA1 or BRCA2 Mutations.
    • Terry MB, Liao Y, Kast K, Antoniou AC, McDonald JA, Mooij TM Engel C, Nogues C Buecher B, Mari V, Moretta-Serra J, Gladieff L, Luporsi E, Barrowdale D, Frost D, Henderson A, Brewer C, Evans DG, Eccles D, Cook J, Ong K, Izatt L, Ahmed M, Morrison PJ, Dommering CJ, Oosterwijk JC, Ausems MGEM, Kriege M, Buys SS, Andrulis IL, John EM, Daly M, Friedlander M, McLachlan SA, Osorio A, Caldes T, Jakubowska A, Simard J, Singer CF, Tan Y, Olah E, Navratilova M, Foretova L, Gerdes AM, Roos-Blom MJ, Arver B, Olsson H, Schmutzler RK, Hopper JL, van Leeuwen FE, Goldgar D, Milne RL, Easton DF, Rookus MA, Andrieu N.
    • JNCI Cancer Spectrum. 2018 Nov 1 [Published 2019 Mar 8];2(4):pky078. doi: 10.1093/jncics/pky078.
    • Improving outcomes for young women with breast cancer: fertility and childbearing issues.
    • [No author given]
    • FORCE. XRAYS. 2019 Jan 7.

    Related:

    ClinicalTrials.gov: Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer (POSITIVE) (NIH. ClinicalTrials.gov.)

    • Pregnancy and Ovarian Stimulation in the Patients with Breast Cancer.
    • Lukáš D, David P, Jaromír M.
    • Klin Onkol. 2018 Fall;31(5):325-329. doi: 10.14735/amko2018325.
    • Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    • Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2018 Sep;171(2):421-426. doi: 10.1007/s10549-018-4822-y. Epub 2018 May 17.
    • Ovarian stimulation for IVF and risk of primary breast cancer in BRCA1/2 mutation carriers.
    • Derks-Smeets IAP, Schrijver LH, de Die-Smulders CEM, Tjan-Heijnen VCG, van Golde RJT, Smits LJ, Caanen B, van Asperen CJ, Ausems M, Collée M, van Engelen K, Kets CM, van der Kolk L, Oosterwijk JC, van Os TAM; HEBON, Rookus MA, van Leeuwen FE, Gómez García EB.
    • Br J Cancer. 2018 May 1 [2018 Aug];119(3):357-363. doi: 10.1038/s41416-018-0139-1.
    • Support needs of couples with hereditary breast and ovarian cancer during reproductive decision-making.
    • Gietel-Habets JJG, de Die-Smulders CEM, Derks-Smeets IAP, Tibben A, Tjan-Heijnen VCG, van Golde R, Gomez-Garcia E, van Osch LADM.
    • Psychooncology. 2018 Jul;27(7):1795-1801. doi: 10.1002/pon.4729. Epub 2018 May 4.
    • Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    • Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2018 May 17. doi: 10.1007/s10549-018-4822-y. [Epub ahead of print]
    • Childbearing after breast cancer among young survivors.
    • [No author given]
    • FORCE. XRAYS. 2018 May 10.

    Related:

    Live birth outcomes after adolescent and young adult breast cancer.

    • Knowledge, attitudes and practice of physicians towards fertility and pregnancy-related issues in youngBRCA-mutated breast cancer patients.
    • Lambertini M, Di Maio M, Poggio F, Pagani O, Curigliano G, Mastro LD, Paluch-Shimon S, Loibl S, Partridge AH, Azim HA Jr, Peccatori FA, Demeestere I.
    • Reprod Biomed Online. 2019 Jan 10. pii: S1472-6483(19)30011-2. doi: 10.1016/j.rbmo.2018.11.031. [Epub ahead of print]
    • BRCA mutations and reproduction.
    • Daum H, Peretz T, Laufer N.
    • Fertil Steril. 2018 Jan;109(1):33-38. doi: 10.1016/j.fertnstert.2017.12.004.
    • Review
    • Fertility and pregnancy issues in BRCA-mutated breast cancer patients.
    • Lambertini M, Goldrat O, Toss A, Azim HA Jr, Peccatori FA, Ignatiadis M, Del Mastro L, Demeestere I.
    • Cancer Treat Rev. 2017 Sep;59:61-70. doi: 10.1016/j.ctrv.2017.07.001. Epub 2017 Jul 14.
    • Review
    • Breast cancer screening of pregnant and breastfeeding women with BRCA mutations.
    • Carmichael H, Matsen C, Freer P, Kohlmann W, Stein M, Buys SS, Colonna S.
    • Breast Cancer Res Treat. 2017 Apr;162(2):225-230. doi: 10.1007/s10549-017-4122-y. Epub 2017 Jan 30.
    • Review

    Related:

    Comments from NSGC Discussion Forum Cancer SIG

    Subject: Article request

    • Breast cancer in pregnancy: an institutional experience.
    • Blanquisett AH, Vicent CH, Gregori JG, Zotano ÁG, Porta VG, Simón AR.
    • Ecancermedicalscience. 2015 Jul 8;9:551. doi: 10.3332/ecancer.2015.551. eCollection 2015.
    • A Rare Case of BRCA2-Associated Breast Cancer in Pregnancy.
    • Leidhin CN, Heeney A, Connolly C, Swan N, Foster A, Geraghty J.
    • Ir Med J. 2015 Jul-Aug;108(7):217-8.
    • The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation.
    • Valentini A, Lubinski J, Byrski T, Ghadirian P, Moller P, Lynch HT, Ainsworth P, Neuhausen SL, Weitzel J, Singer CF, Olopade OI, Saal H, Lyonnet DS, Foulkes WD, Kim-Sing C, Manoukian S, Zakalik D, Armel S, Senter L, Eng C, Grunfeld E, Chiarelli AM, Poll A, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2013 Nov;142(1):177-85. doi: 10.1007/s10549-013-2729-1. Epub 2013 Oct 18.
    • Risk factors for pregnancy-associated breast cancer: a report from the Nigerian Breast Cancer Study.
    • Hou N, Ogundiran T, Ojengbede O, Morhason-Bello I, Zheng Y, Fackenthal J, Adebamowo C, Anetor I, Akinleye S, Olopade OI, Huo D.
    • Ann Epidemiol. 2013 Sep;23(9):551-7. doi: 10.1016/j.annepidem.2013.06.008. Epub 2013 Jul 20.
    • Fertility Preservation and Pregnancy in Women With and Without BRCA Mutation-Positive Breast Cancer.
    • Rodriguez-Wallberg KA, Oktay K.
    • Oncologist. [2012 Nov;]17(11):1409-17. doi: 10.1634/theoncologist.2012-0236. Epub 2012 Sep 24.
    • Treatment of breast cancer during pregnancy: an observational study.
    • Loibl S, Han SN, von Minckwitz G, Bontenbal M, Ring A, Giermek J, Fehm T, Van Calsteren K, Linn SC, Schlehe B, Gziri MM, Westenend PJ, Müller V, Heyns L, Rack B, Van Calster B, Harbeck N, Lenhard M, Halaska MJ, Kaufmann M, Nekljudova V, Amant F.
    • Lancet Oncol. 2012 Sep;13(9):887-96. doi: 10.1016/S1470-2045(12)70261-9. Epub 2012 Aug 16.

    Related:

    Comment:

    Increased evidence for use of chemotherapy in pregnancy.

    Comment:

    Breast cancer: Cancer in pregnancy, to treat or not to treat?

    News:

    Study finds that chemotherapy during pregnancy appears to be safe for babies.

    Press: Cancer Treatment During Pregnancy Feasible. (Medscape)

    • Pregnancy and Fertility for Previvors and Survivors.
    • Jennifer Litton.
    • FORCE. Be Empowered Webinars. 2012 Jun 19.
    • BRCA1/2 carriers: their childbearing plans and theoretical intentions about having preimplantation genetic diagnosis and prenatal diagnosis.
    • Julian-Reynier C, Fabre R, Coupier I, Stoppa-Lyonnet D, Lasset C, Caron O, Mouret-Fourme E, Berthet P, Faivre L, Frenay M, Gesta P, Gladieff L, Bouhnik AD, Protière C, Noguès C.
    • Genet Med. 2012 May;14(5):527-34. doi: 10.1038/gim.2011.27. Epub 2012 Jan 12.