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- Prophylactic Radical Fimbriectomy with Delayed Oophorectomy in Women with a High Risk of Developing an Ovarian Carcinoma: Results of a Prospective National Pilot Study.
- Leblanc E, Narducci F, Ferron G, Mailliez A, Charvolin JY, El Hajj H, Guyon F, Fourchotte V, Lambaudie E, Crouzet A, Fouche Y, Gouy S, Collinet P, Caquant F, Pomel C, Golfier F, Vaini-Cowen V, Fournier I, Salzet M, Tresch E, Probst A, Lemaire AS, Le Deley MC, Hudry D.
- Cancers (Basel). 2023 Feb 10;15(4):1141. doi: 10.3390/cancers15041141.
•• Identifier: NCT01608074: Radical Fimbriectomy for Young BRCA Mutation Carriers (Fimbriectomy). (ClinicalTrials.gov . Accessed 2023 Feb 12.)
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- Uptake and Effectiveness of Risk-Reducing Surgeries in Unaffected Female BRCA1 and BRCA2 Carriers: A Single Institution Experience in the Czech Republic.
- Zimovjanova M, Bielcikova Z, Miskovicova M, Vocka M, Zimovjanova A, Marian Rybar M, Novotny J, Petruzelka L.
- Cancers (Basel). 2023 Feb 8;15(4):1072. doi: 10.3390/cancers15041072.
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- Long-Term Non-Cancer Risks in People with BRCA Mutations following Risk-Reducing Bilateral Salpingo-Oophorectomy and the Role of Hormone Replacement Therapy: A Review.
- Nitschke AS, Abreu do Valle H, Dawson L, Kwon JS, Hanley GE.
- Cancers (Basel). 2023 Jan 24;15(3):711. doi: 10.3390/cancers15030711.
- Review
- Free Full Text
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- The Role of Hormonal Replacement Therapy in BRCA Mutated Patients: Lights and Shadows.
- Loizzi V, Dellino M, Cerbone M, Arezzo F, Cazzato G, Damiani GR, Pinto V, Silvestris E, Kardhashi A, Cicinelli E, Cascardi E, Cormio G.
- Int J Mol Sci. 2023 Jan 1;24(1):764. doi: 10.3390/ijms24010764.
- Review
- Free Full Text
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- The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
- Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA.
- Cancer. 2022 Dec 26. doi: 10.1002/cncr.34615. Epub ahead of print.
- PMID: 36571512
- PubMed abstract
- Source abstract
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- Pathologic Findings at Risk Reducing Surgery in BRCA and Non-BRCA Mutation Carriers: A Single-Center Experience.
- Cassani C, Rossi C, Camnasio CA, Urtis M, Fiandrino G, Grasso M, Zanellini F, Lucioni M, D’Ambrosio G, Di Toro A, Rossi M, Roccio M, Ferrari A, Secondino S, Nappi RE, Arbustini E, Paulli M, Spinillo A, Cesari S.
- Diagnostics (Basel). 2022 Dec 6;12(12):3054. doi: 10.3390/diagnostics12123054.
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- Considerations for the Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy.
- Zhang J, Liu M.
- J Clin Oncol. 2022 Nov 10;40(32):3783. doi: 10.1200/JCO.22.00726. Epub 2022 Jul 12.
- PMID: 35820079
- PubMed abstract
- Letter, Commentary
- Free Full Text
•• Original research:
Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review and Individual Patient Data Meta-Analysis.
- PMID: 35302882
- PubMed abstract
- Source abstract
•• Reply, Letter:
Reply to J. Zhang et al.
- PMID: 35820084
- PubMed abstract
- Free Full Text
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- The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1 and BRCA2.
- Philpott S, Raikou M, Manchanda R, Lockley M, Singh N, Scott M, Evans DG, Adlard J, Ahmed M, Edmondson R, Woodward ER, Lamnisos A, Balega J, Brady AF, Sharma A, Izatt L, Kulkarni A, Tripathi V, Solomons JS, Hayes K, Hanson H, Snape K, Side L, Skates S, McGuire A, Rosenthal AN.
- J Med Genet. 2022 Nov 1:jmedgenet-2022-108741. doi: 10.1136/jmg-2022-108741. Epub ahead of print.
- PMID: 36319079
- PubMed abstract
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- Outcome and management of STIC following opportunistic salpingectomy: systematic review and meta-analysis.
- Ruel-Laliberté J, Kasasni SM, Oprea D, Viau M.
- J Obstet Gynaecol Can. 2022 Sep 10:S1701-2163(22)00612-0. doi: 10.1016/j.jogc.2022.08.018. Epub ahead of print.
- PMID: 36099965
- PubMed abstract
- Source abstract
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- Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics.
- Konishi I, Abiko K, Hayashi T, Yamanoi K, Murakami R, Yamaguchi K, Hamanishi J, Baba T, Matsumura N, Mandai M; Kyoto Study Group for Ovarian Cancer Research.
- J Gynecol Oncol. 2022 Sep;33(5):e83. doi: 10.3802/jgo.2022.33.e83.
- PMID: 36032027
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- A prospective multicentric study of risk-reducing salpingo-oophorectomy in BRCA mutation patients.
- Loizzi V, Cicinelli E, Del Vecchio V, Arezzo F, Deromemaj X, Kardhashi A, Paradiso A, Legge F, Natalicchio MI, Resta L, Resta N, Loconte DC, Cormio G.
- Acta Biomed. 2022 Aug 31;93(4):e2022051. doi: 10.23750/abm.v93i4.11695.
- PMID: 36043985
- PubMed abstract
- Source abstract
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- Incidence of pelvic high-grade serous carcinoma after isolated STIC diagnosis: A systematic review of the literature.
- Linz VC, Löwe A, van der Ven J, Hasenburg A, Battista MJ.
- Front Oncol. 2022 Aug 31;12:951292. doi: 10.3389/fonc.2022.951292.
- PMID: 36119503
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
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- Surgical management of BRCA-mutation carriers: A single institution experience.
- Gentile D, Losurdo A, Sagona A, Zuradelli M, Gatzemeier W, Barbieri E, Testori A, Errico V, Bianchi P, Biondi E, Torrisi R, Santoro A, Tinterri C.
- Eur J Surg Oncol. 2022 Aug;48(8):1706-1712. doi: 10.1016/j.ejso.2022.04.024. Epub 2022 Apr 30.
- PMID: 35534308
- PubMed abstract
- Source abstract
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- Study: Risk-reducing ovarian cancer surgery and quality of life.
- [No author given]
- FORCE. XRAY. 2022 Jul 26.
- Research news
- Free Full Text
Original research:
Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in BRCA1/2 Pathogenic Variant Carriers: A Nonrandomized Controlled Trial.
- PMID: 34081085
- PubMed abstract
- Free Full Text
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- Risk reducing surgery with peritoneal staging in BRCA1-2 mutation carriers. A prospective study.
- Marchetti C, Arcieri M, Vertechy L, Ergasti R, Russo G, Zannoni GF, Minucci A, Ercoli A, Scambia G, Fagotti A.
- Eur J Surg Oncol. 2022 Jul 19:S0748-7983(22)00549-2. doi: 10.1016/j.ejso.2022.07.007. Epub ahead of print.
- PMID: 35871032
- PubMed abstract
- Source abstract
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- Differences in age at diagnosis of ovarian cancer for each BRCA mutation type in Japan: optimal timing to carry out risk-reducing salpingo-oophorectomy.
- Sekine M, Enomoto T, Arai M, Den H, Nomura H, Ikeuchi T, Nakamura S; Registration Committee of the Japanese Organization of Hereditary Breast and Ovarian Cancer.
- J Gynecol Oncol. 2022 Jul;33(4):e46. doi: 10.3802/jgo.2022.33.e46. Epub 2022 Mar 31.
- PMID: 35557031
- PubMed abstract
- Source abstract
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- TP53 variants in p53 signatures and the clonality of STICs in RRSO samples.
- Akahane T, Masuda K, Hirasawa A, Kobayashi Y, Ueki A, Kawaida M, Misu K, Nakamura K, Nagai S, Chiyoda T, Yamagami W, Hayashi S, Kataoka F, Banno K, Sugano K, Okita H, Kosaki K, Nishihara H, Aoki D.
- J Gynecol Oncol. 2022 Jul;33(4):e50. doi: 10.3802/jgo.2022.33.e50. Epub 2022 Mar 21.
- PMID: 35557033
- PubMed abstract
- Source abstract
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- Genomic catastrophe, the peritoneal cavity and ovarian cancer prevention.
- Yoon JY, Chapel DB, Goebel E, Qian X, Mito JK, Horowitz NS, Miron A, Soong TR, Xian W, Crum CP.
- J Pathol. 2022 Jul;257(3):255-261. doi: 10.1002/path.5891. Epub 2022 Apr 18.
- PMID: 35238033
- PubMed abstract
- Source abstract
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- Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review and Individual Patient Data Meta-Analysis.
- Steenbeek MP, van Bommel MHD, Bulten J, Hulsmann JA, Bogaerts J, Garcia C, Cun HT, Lu KH, van Beekhuizen HJ, Minig L, Gaarenstroom KN, Nobbenhuis M, Krajc M, Rudaitis V, Norquist BM, Swisher EM, Mourits MJE, Massuger LFAG, Hoogerbrugge N, Hermens RPMG, IntHout J, de Hullu JA.
- J Clin Oncol. 2022 Jun 10;40(17):1879-1891. doi: 10.1200/JCO.21.02016. Epub 2022 Mar 18.
- PMID: 35302882
- PubMed abstract
- Source abstract
•• Commentary:
Risk of Peritoneal Cancer After Risk-Reducing Bilateral Salpingo-Oophorectomy for Women With Germline BRCA Pathogenic Variants: A Cause for Concern or Potentially Avoidable?
- PMID: 35333598
- PubMed abstract
- Free Full Text
•• Letter, Commentary:
Considerations for the Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy.
- PMID: 35820079
- PubMed abstract
- Free Full Text
•• Reply, Letter:
Reply to J. Zhang et al.
- PMID: 35820084
- PubMed abstract
- Free Full Text
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- Prophylactic Salpingo-Opphorectomy in Patients With Hereditary Predisposition Genes for Ovarian Cancer.
- Garrett AA, Mahdi H.
- JCO Oncol Pract. 2022 Jun;18(6):e846-e848. doi: 10.1200/OP.22.00069. Epub 2022 Mar 8.
- PMID: 35258991
- PubMed abstract
- Source abstract
- Commentary
- Free Full Text
Original research:
Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes.
- PMID: 34582274
- PubMed abstract
- Free Full Text
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- Familial risk of epithelial ovarian cancer after accounting for gynaecological surgery: a population-based study.
- Barnard ME, Meeks H, Jarboe EA, Albro J, Camp NJ, Doherty JA.
- J Med Genet. 2022 May 9:jmedgenet-2021-108402. doi: 10.1136/jmedgenet-2021-108402. Epub ahead of print.
- PMID: 35534206
- PubMed abstract
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- Oral Contraceptive Use in BRCA1 and BRCA2 Mutation Carriers: Absolute Cancer Risks and Benefits.
- Schrijver LH, Mooij TM, Pijpe A, Sonke GS, Mourits MJE, Andrieu N, Antoniou AC, Easton DF, Engel C, Goldgar D, John EM, Kast K, Milne RL, Olsson H, Phillips KA, Terry MB, Hopper JL, van Leeuwen FE, Rookus MA.
- J Natl Cancer Inst. 2022 Apr 11;114(4):540-552. doi: 10.1093/jnci/djac004.
- PMID: 35048954
- PubMed abstract
Commentary:
Oral Contraceptives and BRCA Cancer: A Balancing Act.
- PMID: 35048983
- PubMed abstract
- Free Full Text
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- Fallopian Tube Originating Ovarian Cancer in a 53-Year-Old Postmenopausal Female With Hereditary Breast Cancer (BRCA) Genes: A Case Study.
- Garrick I, Ahasan H, Jiang M, Musheyev Y, Ftiha F, Levada M.
- Cureus. 2022 Apr 7;14(4):e23929. doi: 10.7759/cureus.23929.
- PMID: 35535289
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
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- Consensus Recommendations of the German Consortium for Hereditary Breast and Ovarian Cancer.
- Rhiem K, Auber B, Briest S, Dikow N, Ditsch N, Dragicevic N, Grill S, Hahnen E, Horvath J, Jaeger B, Kast K, Kiechle M, Leinert E, Morlot S, Püsken M, Schäfer D, Schott S, Schroeder C, Siebers-Renelt U, Solbach C, Weber-Lassalle N, Witzel I, Zeder-Göß C, Schmutzler RK.
- Breast Care (Basel). 2022 Apr;17(2):199-207. doi: 10.1159/000516376. Epub 2021 Jul 19.
- PMID: 35702495
- PubMed abstract
- Source abstract
- Guideline, Review
- Free PMC article
- Free Full Text
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- Recommendations for diagnosing STIC: a systematic review and meta-analysis.
- Bogaerts JMA, Steenbeek MP, van Bommel MHD, Bulten J, van der Laak JAWM, de Hullu JA, Simons M.
- Virchows Arch. 2022 Apr;480(4):725-737. doi: 10.1007/s00428-021-03244-w. Epub 2021 Dec 1.
- PMID: 34850262
- PubMed abstract
- Review
- Free Full Text
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- Risk-Reducing Options for High-Grade Serous Gynecologic Malignancy in BRCA1/2.
- Clarfield L, Diamond L, Jacobson M.
- Curr Oncol. 2022 Mar 21;29(3):2132-2140. doi: 10.3390/curroncol29030172.
- PMID: 35323372
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes.
- Liu YL, Breen K, Catchings A, Ranganathan M, Latham A, Goldfrank DJ, Grisham RN, Long Roche K, Frey MK, Chi DS, Abu-Rustum N, Aghajanian C, Offit K, Stadler ZK.
- JCO Oncol Pract. 2022 Mar;18(3):201-209. doi: 10.1200/OP.21.00382. Epub 2021 Sep 28.
- PMID: 34582274
- PubMed abstract
- Source abstract
- Review, Guideline
- Free Full Text
Commentary:
Prophylactic Salpingo-Opphorectomy in Patients With Hereditary Predisposition Genes for Ovarian Cancer.
- PMID: 35258991
- PubMed abstract
- Free Full Text
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- Earlier decisions on breast and ovarian surgery reduce cancer in women at high risk.
- Saul H, Gursul D, Cassidy S, Evans G.
- BMJ. 2022 Feb 15;376:o258. doi: 10.1136/bmj.o258.
- PMID: 35168943
- PubMed abstract
- Source abstract
Original research:
Uptake and efficacy of bilateral risk reducing surgery in unaffected female BRCA1 and BRCA2 carriers.
- PMID: 33568438
- PubMed abstract
- Source abstract
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- Serous Tubal Intraepithelial Carcinoma in a Risk-reducing Salpingo-oophorectomy Specimen From a RAD51D Mutation Carrier: A Case Report.
- Gregory-Davis KJ, Walker A, Colello LS, McKinnon W, Everett E, Chang MC.
- Int J Gynecol Pathol. 2022 Feb 11. doi: 10.1097/PGP.0000000000000857. Epub ahead of print.
- PMID: 35149617
- PubMed abstract
- Source abstract
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- Chris Evert's ovarian cancer diagnosis highlights the importance of genetic counseling and testing.
- [No author given]
- FORCE. XRAY. 2022 Feb 8.
- News
- Free Full Text
Press: Chris Evert opens up about her stage 1C ovarian cancer diagnosis. (ESPN)
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- Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2.
- Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S.
- Cells. 2022 Feb 4;11(3):539. doi: 10.3390/cells11030539.
- PMID: 35159349
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- Uptake and efficacy of bilateral risk reducing surgery in unaffected female BRCA1 and BRCA2 carriers.
- Marcinkute R, Woodward ER, Gandhi A, Howell S, Crosbie EJ, Wissely J, Harvey J, Highton L, Murphy J, Holland C, Edmondson R, Clayton R, Barr L, Harkness EF, Howell A, Lalloo F, Evans DG.
- J Med Genet. 2022 Feb;59(2):133-140. doi: 10.1136/jmedgenet-2020-107356. Epub 2021 Feb 10.
- PMID: 33568438
- PubMed abstract
- Source abstract
Research news:
Earlier decisions on breast and ovarian surgery reduce cancer in women at high risk.
- PMID: 35168943
- PubMed abstract
- Source abstract
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- Long-term tumour dormancy in a BRCA1 heterozygote.
- Amuzu S, Fu L, Demko N, Rivera B, Domecq C, de Kock L, Hamel N, Gilbert L, Polak P, Ragoussis J, Foulkes WD.
- J Med Genet. 2022 Jan 17:jmedgenet-2021-108269. doi: 10.1136/jmedgenet-2021-108269. Epub ahead of print.
- PMID: 35039446
- PubMed abstract
- Source abstract
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- Tubal histopathological abnormalities in BRCA1/2 mutation carriers undergoing prophylactic salpingo-oophorectomy: a case-control study.
- Sina F, Cassani C, Comerio C, De Ponti E, Zanellini F, Delle Marchette M, Roversi G, Jaconi M, Arbustini E, Urtis M, Dell'Oro C, Zambetti B, Paniga C, Acampora E, Negri S, Lazzarin S, Cesari S, Spinillo A, Kotsopoulos J, Fruscio R.
- Int J Gynecol Cancer. 2022 Jan;32(1):41-47. doi: 10.1136/ijgc-2021-003153. Epub 2021 Nov 29.
- PMID: 34845040
- PubMed abstract
- Source abstract
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- Evidence for Diverse Prognosis in High-Grade Serous Ovarian Carcinoma: Solid, Pseudoendometrioid, and Transitional-Like; So-Called "SET Morphology" and Progesterone Receptor Status.
- Uner H, Demir M, Goksuluk D, Kars A, Uner M, Usubutun A.
- Turk Patoloji Derg. 2022;38(3):240-250. English. doi: 10.5146/tjpath.2022.01571.
- PMID: 35147976
- PubMed abstract
- Source abstract
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- Metastatic ovarian carcinoma in breast cancer patients during risk-reducing salpingo-oophorectomy: Report of two cases.
- Shakya P, Bajracharya A, Shrestha S, Kharel S, Maharjan R, Shrestha AK.
- Ann Med Surg (Lond). 2021 Dec 6;73:103158. doi: 10.1016/j.amsu.2021.103158. eCollection 2022 Jan.
- PMID: 34976386
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
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- Uptake Rate of Risk-Reducing Salpingo-Oophorectomy and Surgical Outcomes of Female Germline BRCA1/2 Mutation Carriers: A Retrospective Cohort Study.
- Lim H, Kim SI, Hyun S, Lee GB, Seol A, Lee M.
- Yonsei Med J. 2021 Dec;62(12):1090-1097. doi: 10.3349/ymj.2021.62.12.1090.
- PMID: 34816639
- PubMed abstract
- Source abstract
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- Association of Premenopausal Bilateral Oophorectomy With Cognitive Performance and Risk of Mild Cognitive Impairment.
- Rocca WA, Lohse CM, Smith CY, Fields JA, Machulda MM, Mielke MM.
- JAMA Netw Open. 2021 Nov 1;4(11):e2131448. doi: 10.1001/jamanetworkopen.2021.31448.
- PMID: 34762113
- PubMed abstract
Commentary:
Long-term Risk of Cognitive Impairment and Dementia Following Bilateral Oophorectomy in Premenopausal Women-Time to Rethink Policies?
- PMID: 34762116
- PubMed abstract
- Free Full Text
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- Efficacy of risk-reducing salpingo-oophorectomy in BRCA1-2 variants and clinical outcomes of follow-up in patients with isolated serous tubal intraepithelial carcinoma (STIC).
- Saccardi C, Zovato S, Spagnol G, Bonaldo G, Marchetti M, Alessandrini L, Tognazzo S, Guerriero A, Vitagliano A, Laganà AS, Noventa M.
- Gynecol Oncol. 2021 Nov;163(2):364-370. doi: 10.1016/j.ygyno.2021.08.021. Epub 2021 Aug 28.
- PMID: 34465478
- PubMed abstract
- Source abstract
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- What happens after menopause? (WHAM): A prospective controlled study of vasomotor symptoms and menopause-related quality of life 12 months after premenopausal risk-reducing salpingo-oophorectomy.
- Hickey M, Moss KM, Krejany EO, Wrede CD, Brand A, Kirk J, Symecko HL, Domchek SM, Tejada-Berges T, Trainer A, Mishra GD.
- Gynecol Oncol. 2021 Oct;163(1):148-154. doi: 10.1016/j.ygyno.2021.07.029. Epub 2021 Jul 24.
- PMID: 34312002
- PubMed abstract
- Source abstract
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- Role of Routine Peritoneal Biopsies During Risk Reducing Salpingo-Oophorectomy (RRSO).
- Pross T, Karsten MM, Blohmer JU, Speiser D.
- Geburtshilfe Frauenheilkd. 2021 Sep;81(9):1031-1038. doi: 10.1055/a-1395-7715. Epub 2021 Sep 13.
- PMID: 34531609
- PubMed abstract
- Source abstract
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- Risk of cardiovascular disease among women carrying BRCA mutations after risk-reducing bilateral salpingo-oophorectomy: A population-based study.
- do Valle HA, Kaur P, Kwon JS, Cheifetz R, Dawson L, Hanley GE.
- Gynecol Oncol. 2021 Sep;162(3):707-714. doi: 10.1016/j.ygyno.2021.06.022. Epub 2021 Jul 1.
- PMID: 34217543
- PubMed abstract
- Source abstract
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- Surgical Management of Hereditary Breast Cancer.
- Berger ER, Golshan M.
- Genes (Basel). 2021 Aug 31;12(9):1371. doi: 10.3390/genes12091371.
- PMID: 34573353
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
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- Clinical and pathological outcomes of risk-reducing salpingo-oophorectomy for Japanese women with hereditary breast and ovarian cancer.
- Nomura H, Ikki A, Fusegi A, Omi M, Aoki Y, Netsu S, Tanigawa T, Matoda M, Okamoto S, Omatsu K, Nakajima T, Ueki A, Tonooka A, Kanao H.
- Int J Clin Oncol. 2021 Aug 28. doi: 10.1007/s10147-021-02020-9. Epub ahead of print.
- PMID: 34453642
- PubMed abstract
- Source abstract
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- The impact of risk reducing bilateral salpingo-oophorectomy on sexual function in BRCA1/2 mutation carriers and women with Lynch syndrome: A systematic review and meta-analysis.
- Kershaw V, Hickey I, Wyld L, Jha S.
- Eur J Obstet Gynecol Reprod Biol. 2021 Aug 8;265:7-17. doi: 10.1016/j.ejogrb.2021.08.001. Epub ahead of print.
- PMID: 34416580
- PubMed abstract
- Source abstract
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- Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in BRCA1/2 Pathogenic Variant Carriers: A Nonrandomized Controlled Trial.
- Steenbeek MP, Harmsen MG, Hoogerbrugge N, de Jong MA, Maas AHEM, Prins JB, Bulten J, Teerenstra S, van Bommel MHD, van Doorn HC, Mourits MJE, van Beurden M, Zweemer RP, Gaarenstroom KN, Slangen BFM, Brood-van Zanten MMA, Vos MC, Piek JMJ, van Lonkhuijzen LRCW, Apperloo MJA, Coppus SFPJ, Massuger LFAG, IntHout J, Hermens RPMG, de Hullu JA.
- JAMA Oncol. 2021 Aug 1;7(8):1203-1212. doi: 10.1001/jamaoncol.2021.1590.
- PMID: 34081085
- PubMed abstract
Identifier: NCT02321228: Early Salpingectomy (Tubectomy) With Delayed Oophorectomy in BRCA1/2 Gene Mutation Carriers (TUBA). (ClinicalTrials.gov)
Research news: Study: Risk-reducing ovarian cancer surgery and quality of life. (FORCE. XRAY.)
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- What happens after menopause? (WHAM): A prospective controlled study of sleep quality up to 12 months after premenopausal risk-reducing salpingo-oophorectomy.
- Hickey M, Moss KM, Krejany EO, Wrede CD, Domchek SM, Kirk J, Brand A, Trainer A, Mishra GD, Baker FC.
- Gynecol Oncol. 2021 Aug;162(2):447-453. doi: 10.1016/j.ygyno.2021.05.036. Epub 2021 Jun 8.
- PMID: 34116835
- PubMed abstract
- Source abstract
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- Follow-up of tissue genomics in BRCA1/2 carriers who underwent prophylactic surgeries.
- Kotoula V, Papadopoulou K, Tikas I, Fostira F, Vrettou E, Chrisafi S, Fountzilas E, Koliou GA, Apostolou P, Papazisis K, Zaramboukas T, Asimaki-Vlachopoulou A, Miliaras S, Ananiadis A, Poulios C, Natsiopoulos I, Tsiftsoglou A, Demiri E, Fountzilas G.
- Breast Cancer. 2021 Jul 24. doi: 10.1007/s12282-021-01276-3. Epub ahead of print.
- PMID: 34304347
- PubMed abstract
- Source abstract
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- Risk of epithelial ovarian cancer Type I and II after hysterectomy, salpingectomy and tubal ligation - A nationwide case control study.
- Darelius A, Kristjansdottir B, Dahm-Kähler P, Strandell A.
- Int J Cancer. 2021 Jun 21. doi: 10.1002/ijc.33714. Epub ahead of print.
- PMID: 34152012
- PubMed abstract
- Source abstract
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- An evaluation of memory and attention in BRCA mutation carriers using an online cognitive assessment tool.
- Kotsopoulos J, Kim SJ, Armel S, Bordeleau L, Foulkes WD, McKinnon W, Panchal S, Cohen SA, Sun S, Sun P, McKetton L, Troyer AK, Narod SA.
- Cancer. 2021 Jun 2. doi: 10.1002/cncr.33654. Epub ahead of print.
- PMID: 34077552
- PubMed abstract
- Source abstract
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- Gynecological lesions in hereditary cancer predisposition syndromes.
- Dundr P, Cibula D, Foretová L, Macek M Jr, Kopecková K, Petruželka L, Nemejcová K, Bártu M, Hojný J, Hájková N, Jakša R, Janega P, Stružinská I.
- Cesk Patol. 2021 Summer;57(2):96-104. English.
- PMID: 34275319
- PubMed abstract
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- Review
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- Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low levels.
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- Assessing Effectiveness of Colonic and Gynecological Risk Reducing Surgery in Lynch Syndrome Individuals.
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- Radiologic-Histopathologic Correlation of Transvaginal US and Risk-reducing Salpingo-oophorectomy for Women at High Risk for Tubo-ovarian Carcinoma.
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- Penetrance of Breast and Ovarian Cancer in Women Who Carry a BRCA1/2 Mutation and Do Not Use Risk-Reducing Salpingo-Oophorectomy: An Updated Meta-Analysis.
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- Ovarian Cancer After Prophylactic Salpingectomy in a Patient With Germline BRCA1 Mutation.
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- The prevalence of occult ovarian cancer in the series of 155 consequently operated high risk asymptomatic patients - Slovenian population based study.
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Comments on NSGC Discussion Forum Cancer SIG:
Subject: BRCA1 loss of expression in Uetrine Serous carcinoma
Subject: Register for August webinar, July webinar slides and recording posted
Webinar: Cancer SIG Aug Journal Club: Uterine Cancer After RRSO w/o Hysterectomy in Women with BRCA mutations. (NSGC. Cancer SIG Journal Club.)
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Letter, Comment:
Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions--letter.
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Letter, Reply:
Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions--response.
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- Long term follow up of BRCA1 and BRCA2 mutation carriers with unsuspected neoplasia identified at risk reducing salpingo-oophorectomy.
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- Salpingectomy: Can removing the fallopian tubes lower ovarian cancer risk?
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- FORCE. Be Empowered Webinars. 2013 Apr 11.
- Webinar
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- Endometrium is not the primary site of origin of pelvic high-grade serous carcinoma in BRCA1 or BRCA2 mutation carriers.
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- Pre-diagnosis oophorectomy, estrogen therapy and mortality in a cohort of women diagnosed with breast cancer.
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- Tubal epithelial lesions in salpingo-oophorectomy specimens of BRCA-mutation carriers and controls.
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- Peritoneal cytology in risk-reducing salpingo-oophorectomy: Implications for cancer outcomes.
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- A simulation model to predict the impact of prophylactic surgery and screening on the life expectancy of BRCA1 and BRCA2 mutation carriers.
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- Effectiveness of risk-reducing salpingo-oophorectomy in preventing ovarian cancer in a high-risk French Canadian population.
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- Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers.
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- Online tool to guide decisions for BRCA1/2 mutation carriers.
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Comments from NSGC Discussion Forum Cancer SIG
Subject: An Online BRCA Positive Decision Guidance Tool.
Comment:
Are we ready for online tools in decision making for BRCA1/2 mutation carriers?
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Press: Are We Ready for Online Tools in Decision Making for BRCA1/2 Mutation Carriers? (Journal of Clinical Oncology)
Press: Online tool helps those with BRCA mutations understand options. (Medical Xpress)
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- Physician data query (PDQ®) update.
- [No authors listed]
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