Primarily chemotherapy, but includes all treatment modalities except surgery and radiation.
List was last updated on
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- Durvalumab compared to maintenance chemotherapy in metastatic breast cancer: the randomized phase II SAFIR02-BREAST IMMUNO trial.
- Bachelot T, Filleron T, Bieche I, Arnedos M, Campone M, Dalenc F, Coussy F, Sablin MP, Debled M, Lefeuvre-Plesse C, Goncalves A, Reynier MM, Jacot W, You B, Barthelemy P, Verret B, Isambert N, Tchiknavorian X, Levy C, Thery JC, L'Haridon T, Ferrero JM, Mege A, Del Piano F, Rouleau E, Tran-Dien A, Adam J, Lusque A, Jimenez M, Jacquet A, Garberis I, Andre F.
- Nat Med. 2021 Jan 18. doi: 10.1038/s41591-020-01189-2. Epub ahead of print.
- PMID: 33462450
- PubMed abstract
- Source abstract
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- Triple-Negative Breast Cancer and the COVID-19 Pandemic: Clinical Management Perspectives and Potential Consequences of Infection.
- Brown JM, Wasson MCD, Marcato P.
- Cancers (Basel). 2021 Jan 15;13(2):E296. doi: 10.3390/cancers13020296.
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- Estimation of healthcare-related charges in women with BRCA mutations and breast cancer.
- Biskupiak J, Unni S, Telford C, Yoo M, Ye X, Deka R, Brixner D, Stenehjem D.
- BMC Health Serv Res. 2021 Jan 13;21(1):58. doi: 10.1186/s12913-020-06038-z.
- PMID: 33435985
- PubMed abstract
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- American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Guideline for Management of Hereditary Breast Cancer.
- Yip CH, Newman LA.
- JAMA Surg. 2021 Jan 13. doi: 10.1001/jamasurg.2020.6254. Epub ahead of print.
- PMID: 33439213
- PubMed abstract
- Source abstract
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- Insights Into the Impacts of BRCA Mutations on Clinicopathology and Management of Early-Onset Triple-Negative Breast Cancer.
- Ye F, He M, Huang L, Lang G, Hu X, Shao Z, Di G, Cao A.
- Front Oncol. 2021 Jan 11;10:574813. doi: 10.3389/fonc.2020.574813.
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- Targeting mTOR and DNA repair pathways in residual triple negative breast cancer post neoadjuvant chemotherapy.
- Anand K, Patel T, Niravath P, Rodriguez A, Darcourt J, Belcheva A, Boone T, Ensor J, Chang J.
- Sci Rep. 2021 Jan 8;11(1):82. doi: 10.1038/s41598-020-80081-y.
- PMID: 33420229
- PubMed abstract
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- Germline BRCA1/2 mutations and severe haematological toxicities in patients with breast cancer treated with neoadjuvant chemotherapy.
- Furlanetto J, Möbus V, Schneeweiss A, Rhiem K, Tesch H, Blohmer JU, Lübbe K, Untch M, Salat C, Huober J, Klare P, Schmutzler R, Couch FJ, Lederer B, Gerber B, Zahm DM, Bauerfeind I, Nekljudova V, Hanusch C, Jackisch C, Link T, Hahnen E, Loibl S, Fasching PA.
- Eur J Cancer. 2021 Jan 7;145:44-52. doi: 10.1016/j.ejca.2020.12.007. Epub ahead of print.
- PMID: 33423006
- PubMed abstract
- Source abstract
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- Modulation of Early Mitotic Inhibitor 1 (EMI1) depletion on the sensitivity of PARP inhibitors in BRCA1 mutated triple-negative breast cancer cells.
- Moustafa D, Elwahed MRA, Elsaid HH, Parvin JD.
- PLoS One. 2021 Jan 7;16(1):e0235025. doi: 10.1371/journal.pone.0235025.
- PMID: 33412559
- PubMed abstract
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- Generating real-world evidence from unstructured clinical notes to examine clinical utility of genetic tests: use case in BRCAness.
- Zhao Y, Weroha SJ, Goode EL, Liu H, Wang C.
- BMC Med Inform Decis Mak. 2021 Jan 6;21(1):3. doi: 10.1186/s12911-020-01364-y.
- PMID: 33407429
- PubMed abstract
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- PARPi, immunothérapies et anticorps monoclonaux conjugués dans les cancers du sein triple-négatifs [Recent therapeutic trends in triple-negative metastatic breast cancers: PARP inhibitors, immunotherapies and antibody-drug conjugates].
- Dalenc F, Sarradin V, Nicolaï V, Franchet C, Ung M.
- Bull Cancer. 2021 Jan 6:S0007-4551(20)30504-X. French. doi: 10.1016/j.bulcan.2020.11.007. Epub ahead of print.
- PMID: 33422340
- PubMed abstract
- Source abstract
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- Metaplastic carcinoma of the breast and BRCA1 germline mutation: a case report and review.
- Yamashita M, Kamei Y, Murakami A, Ozaki E, Okujima K, Takemoto K, Takaoka M, Tsukamoto D, Kusakabe E, Shidahara T, Noda H, Aoki R, Taguchi K, Nishiyama K, Eguchi M, Takada Y.
- Hered Cancer Clin Pract. 2021 Jan 6;19(1):3. doi: 10.1186/s13053-020-00162-x.
- PMID: 33407746
- PubMed abstract
- Free Full Text
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- BRCA testing and outcomes in women with breast cancer.
- Stenehjem DD, Telford C, Unni SK, Bauer H, Sainski A, Deka R, Schauerhamer MB, Ye X, Tak CR, Ma J, Dalvi TB, Gutierrez L, Kaye JA, Tyczynski JE, Brixner DI, Biskupiak JE.
- Breast Cancer Res Treat. 2021 Jan 3. doi: 10.1007/s10549-020-06038-x. Epub ahead of print.
- PMID: 33389410
- PubMed abstract
- Source abstract
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- Efficacy of cancer vaccines in selected gynaecological breast and ovarian cancers: A 20-year systematic review and meta-analysis.
- Dafni U, Martín-Lluesma S, Balint K, Tsourti Z, Vervita K, Chenal J, Coukos G, Zaman K, Sarivalasis A, Kandalaft LE.
- Eur J Cancer. 2021 Jan;142:63-82. doi: 10.1016/j.ejca.2020.10.014. Epub 2020 Nov 19.
- PMID: 33221598
- PubMed abstract
- Source abstract
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- PARP inhibitor resistance and TP53 mutations in patients treated with olaparib for BRCA-mutated cancer: Four case reports.
- Collot T, Niogret J, Carnet M, Chevrier S, Humblin E, Favier L, Bengrine-Lefevre L, Desmoulins I, Arnould L, Boidot R.
- Mol Med Rep. 2021 Jan;23(1):75. doi: 10.3892/mmr.2020.11713. Epub 2020 Nov 25.
- PMID: 33236159
- PubMed abstract
- Source abstract
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- Integrating PARP inhibitors into the management of breast cancer: where are we?
- Azim HA, Kassem L, Azim H Jr.
- Chin Clin Oncol. 2020 Dec 31:cco-19-230. doi: 10.21037/cco-19-230. Epub ahead of print.
- PMID: 33440946
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- Phase II study of eribulin in combination with gemcitabine for the treatment of patients with locally advanced or metastatic triple negative breast cancer (ERIGE trial). Clinical and pharmacogenetic results on behalf of the Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC).
- Pellegrino B, Cavanna L, Boggiani D, Zamagni C, Frassoldati A, Schirone A, Caldara A, Rocca A, Gori S, Piacentini F, Berardi R, Brandes AA, Foglietta J, Villa F, Todeschini R, Tognetto M, Naldi N, Bortesi B, Montemurro F, Ardizzoni A, Boni L, Musolino A.
- ESMO Open. 2020 Dec 31;6(1):100019. doi: 10.1016/j.esmoop.2020.100019. Epub ahead of print.
- PMID: 33399082
- PubMed abstract
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- Immunosuppressive Macrophages Limit PARP Inhibitor Efficacy in TNBC.
- [No author given]
- Cancer Discov. 2020 Dec 30:CD-RW2020-185. doi: 10.1158/2159-8290.CD-RW2020-185. Epub ahead of print.
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- Value of adjuvant chemotherapy and informed microscopic examination for occult gynecologic cancer detected upon risk-reducing salpingo-oophorectomy after chemotherapy for BRCA1/2-associated breast cancer: a case report.
- Kuji S, Kondo H, Ohara T, Deura I, Tozawa-Ono A, Migita O, Kawamoto H, Tsugawa K, Chosokabe M, Koike J, Maeda I, Suzuki N.
- Jpn J Clin Oncol. 2020 Dec 30:hyaa239. doi: 10.1093/jjco/hyaa239. Epub ahead of print.
- PMID: 33377156
- PubMed abstract
- Source abstract
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- Advances in Therapeutic Approaches for Triple Negative Breast Cancer.
- Mahtani R, Kittaneh M, Kalinsky K, Mamounas E, Badve S, Vogel C, Lower E, Schwartzberg L, Pegram M.
- Clin Breast Cancer. 2020 Dec 28:S1526-8209(20)30339-6. doi: 10.1016/j.clbc.2020.12.011. Epub ahead of print.
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- Surgical Treatment after Neoadjuvant Systemic Therapy in Young Women with Breast Cancer: Results from a Prospective Cohort Study.
- Kim HJ, Dominici L, Rosenberg SM, Zheng Y, Pak LM, Poorvu PD, Ruddy KJ, Tamimi R, Schapira L, Come SE, Peppercorn J, Borges VF, Warner E, Vardeh H, Collins LC, Gaither R, King TA, Partridge AH.
- Ann Surg. 2020 Dec 23;Publish Ahead of Print. doi: 10.1097/SLA.0000000000004296. Epub ahead of print.
- PMID: 33378304
- PubMed abstract
- Source abstract
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- Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer.
- Mehta AK, Cheney EM, Hartl CA, Pantelidou C, Oliwa M, Castrillon JA, Lin JR, Hurst KE, de Oliveira Taveira M, Johnson NT, Oldham WM, Kalocsay M, Berberich MJ, Boswell SA, Kothari A, Johnson S, Dillon DA, Lipschitz M, Rodig S, Santagata S, Garber JE, Tung N, Yélamos J, Thaxton JE, Mittendorf EA, Sorger PK, Shapiro GI, Guerriero JL.
- Nat Cancer. 2020 Dec 14:1-2. doi: 10.1038/s43018-020-00148-7. Epub ahead of print.
Research news: PARP Inhibitor Breast Cancer Treatments May Be Improved by Targeting Immunosuppressive Macrophages (Clinical OMICs)
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- Dextran-modified Quercetin-Cu(II)/hyaluronic acid nanomedicine with natural poly(ADP-ribose) polymerase inhibitor and dual targeting for programmed synthetic lethal therapy in triple-negative breast cancer.
- Cheng HW, Chiang CS, Ho HY, Chou SH, Lai YH, Shyu WC, Chen SY.
- J Control Release. 2020 Dec 2:S0168-3659(20)30718-5. doi: 10.1016/j.jconrel.2020.11.061. Epub ahead of print.
- PMID: 33278482
- PubMed abstract
- Source abstract
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- Biomarkers in Her2- Positive Disease.
- Klocker EV, Suppan C.
- Breast Care (Basel). 2020 Dec;15(6):586-593. doi: 10.1159/000512283. Epub 2020 Oct 28.
- PMID: 000512283
- PubMed abstract
- Source abstract
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- Novel Therapies for Triple-Negative Breast Cancer.
- Nanda R.
- Clin Adv Hematol Oncol. 2020 Dec;18(12).
- Review
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- Triple-negative breast cancer therapy: Current and future perspectives (Review).
- Won KA, Spruck C.
- Int J Oncol. 2020 Dec;57(6):1245-1261. doi: 10.3892/ijo.2020.5135. Epub 2020 Oct 16.
- PMID: 33174058
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
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- Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1).
- Zhang Z, Chang X, Zhang C, Zeng S, Liang M, Ma Z, Wang Z, Huang W, Shen Z.
- J Enzyme Inhib Med Chem. 2020 Dec;35(1):1606-1615. doi: 10.1080/14756366.2020.1804382.
- PMID: 32779949
- PubMed abstract
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- A Review of Natural Therapies Potentially Relevant in Triple Negative Breast Cancer Aimed at Targeting Cancer Cell Vulnerabilities.
- Webb MJ, Kukard C.
- Integr Cancer Ther. 2020 Jan-Dec;19:1534735420975861. doi: 10.1177/1534735420975861. [First Published November 27, 2020.]
- PMID: 33243021
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- Comparative efficacy, safety, and acceptability of single-agent poly (ADP-ribose) polymerase (PARP) inhibitors in BRCA-mutated HER2-negative metastatic or advanced breast cancer: a network meta-analysis.
- Wang J, Zhang Y, Yuan L, Ren L, Zhang Y, Qi X.
- Aging (Albany NY). 2020 Nov 30;12. doi: 10.18632/aging.202152. Epub ahead of print.
- PMID: 33257598
- PubMed abstract
- Review
- Free Full Text
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- New Perspectives for Resistance to PARP Inhibitors in Triple-Negative Breast Cancer.
- Han Y, Yu X, Li S, Tian Y, Liu C.
- Front Oncol. 2020 Nov 25;10:578095. doi: 10.3389/fonc.2020.578095.
- Review
- Free Full Text
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- Insights into the impacts of BRCA mutations on clinicopathology and management of early-onset triple-negative breast cancer.
- Ye F, He M, Huang L, Lang G, Hu X, Shao Z, Di G, Cao A.
- Front Oncol. 2020 Nov 24;10:574813. doi: 10.3389/fonc.2020.574813.
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- Olaparib Monotherapy as Primary Treatment in Unselected Triple Negative Breast Cancer.
- Eikesdal HP, Yndestad S, Elzawahry A, Llop-Guevara A, Gilje B, Blix ES, Espelid H, Lundgren S, Geisler J, Vagstad G, Venizelos A, Minsaas L, Leirvaag B, Gudlaugsson EG, Vintermyr OK, Aase HS, Aas T, Balmaña J, Serra V, Janssen EAM, Knappskog S, Lønning PE.
- Ann Oncol. 2020 Nov 23:S0923-7534(20)43164-3. doi: 10.1016/j.annonc.2020.11.009. Epub ahead of print.
- PMID: 33242536
- PubMed abstract
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- Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy.
- Singh B, Yang S, Krishna A, Sridhar S.
- Front Chem. 2020 Nov 23;8:594619. doi: 10.3389/fchem.2020.594619.
- PMID: 33330383
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
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- Triple-negative breast cancer: promising prognostic biomarkers currently in development.
- Sukumar J, Gast K, Quiroga D, Lustberg M, Williams N.
- Expert Rev Anticancer Ther. 2020 Nov 16. doi: 10.1080/14737140.2021.1840984. Epub ahead of print.
- PMID: 33198517
- PubMed abstract
- Source abstract
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- Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.
- Samstein RM, Krishna C, Ma X, Pei X, Lee KW, Makarov V, Kuo F, Chung J, Srivastava RM, Purohit TA, Hoen DR, Mandal R, Setton J, Wu W, Shah R, Qeriqi B, Chang Q, Kendall S, Braunstein L, Weigelt B, Carrillo Albornoz PB, Morris LGT, Mandelker DL, Reis-Filho JS, de Stanchina E, Powell SN, Chan TA, Riaz N.
- Nat Cancer. 2020 Nov 16:1-9. doi: 10.1038/s43018-020-00139-8. Epub ahead of print.
Research news: Cancer Patients With BRCA1/2 Mutations Respond Differently to Immunotherapy, Study Shows. (Precision Oncology News; subscription required)
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- Clinical Challenges in the Management of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer: A Literature Review.
- Nagaraj G, Ma CX.
- Adv Ther. 2020 Nov 15. doi: 10.1007/s12325-020-01552-2. Epub ahead of print.
- PMID: 33190190
- PubMed abstract
- Review
- Free Full Text
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- A review of current progress in triple-negative breast cancer therapy.
- Shen M, Pan H, Chen Y, Xu YH, Yang W, Wu Z.
- Open Med (Wars). 2020 Nov 14;15(1):1143-1149. doi: 10.1515/med-2020-0138.
- PMID: 33336070
- PubMed abstract
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- Review
- Free PMC article
- Free Full Text
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- Editorial: Hereditary Breast and Ovarian Cancer: Current Concepts of Prevention and Treatment.
- Grabenstetter A, Lazaro C, Turashvili G.
- Front Oncol. 2020 Nov 11;10:618369. doi: 10.3389/fonc.2020.618369.
- Review
- Free Full Text
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- Update Breast Cancer 2020 Part 4 - Advanced Breast Cancer.
- Tesch H, Müller V, Wöckel A, Ettl J, Belleville E, Schütz F, Hartkopf A, Thill M, Huober J, Fasching PA, Kolberg HC, Schulmeyer CE, Welslau M, Overkamp F, Fehm TN, Lux MP, Schneeweiss A, Lüftner D, Janni W.
- Geburtshilfe Frauenheilkd. 2020 Nov;80(11):1115-1122. doi: 10.1055/a-1270-7481. Epub 2020 Nov 6.
- PMID: 33173239
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
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- Ideaya Biosciences, Broad Institute Partner on Synthetic Lethality-Based Cancer Drug Discovery.
- [No author given]
- GenomeWeb. Technology. Gene Silencing/Gene Editing. 2020 Oct 22.
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- Innovations in targeted therapies for triple negative breast cancer.
- McCann KE, Hurvitz SA.
- Curr Opin Obstet Gynecol. 2020 Oct 21. doi: 10.1097/GCO.0000000000000671. Epub ahead of print.
- PMID: 33093337
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- PARP Inhibitors in Cancer Diagnosis and Therapy.
- Chan CY, Tan KV, Cornelissen B.
- Clin Cancer Res. 2020 Oct 20:clincanres.2766.2020. doi: 10.1158/1078-0432.CCR-20-2766. Epub ahead of print.
- PMID: 33082213
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- Surgical and Systemic Treatment of Hereditary Breast Cancer: A Mini-Review With a Focus on BRCA1 and BRCA2 Mutations.
- Pouptsis A, Swafe L, Patwardhan M, Stavraka C.
- Front Oncol. 2020 Oct 20;10:553080. doi: 10.3389/fonc.2020.553080. PMID: 33194613; PMCID: PMC7607003.
- PMID: 33194613
- PubMed abstract
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- Free PMC article
- Free Full Text
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- Repurposing denosumab in breast cancer beyond prevention of skeletal related events: could nonclinical data be translated into clinical practice?
- Deligiorgi MV, Panayiotidis MI, Trafalis DT.
- Expert Rev Clin Pharmacol. 2020 Oct 17. doi: 10.1080/17512433.2020.1839416. Epub ahead of print.
- PMID: 33070648
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- Novel Agents for Metastatic Triple-Negative Breast Cancer: Finding the Positive in the Negative.
- Vidula N, Ellisen LW, Bardia A.
- J Natl Compr Canc Netw. 2020 Oct 15:1-9. doi: 10.6004/jnccn.2020.7600. Epub ahead of print.
- PMID: 33075745
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- Review
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- The DNA damaging revolution.
- Cetin B, Wabl CA, Gumusay O.
- Crit Rev Oncol Hematol. 2020 Oct 3;156:103117. doi: 10.1016/j.critrevonc.2020.103117. Epub ahead of print.
- PMID: 33059228
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- Was ist neu bei der Diagnostik und Therapie des Mammakarzinoms? – Aktuelle Standards in der Behandlung von Brustkrebs [Breast cancer - state of the art - Short overview of the current standard of treatment].
- Albert A, Stüber T, Bauer J, Wöckel A.
- Dtsch Med Wochenschr. 2020 Oct;145(20):1460-1463. German. doi: 10.1055/a-1026-3620. Epub 2020 Oct 6.
- PMID: 33022726
- PubMed abstract
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- Frequency and molecular characteristics of PALB2-associated cancers in Russian patients.
- Preobrazhenskaya EV, Shleykina AU, Gorustovich OA, Martianov AS, Bizin IV, Anisimova EI, Sokolova TN, Chuinyshena SA, Kuligina ES, Togo AV, Belyaev AM, Ivantsov AO, Sokolenko AP, Imyanitov EN.
- Int J Cancer. 2020 Sep 30. doi: 10.1002/ijc.33317. Epub ahead of print.
- PMID: 32997802
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- Effects of germline and somatic events in candidate BRCA-like genes on breast-tumor signatures.
- Bodily WR, Shirts BH, Walsh T, Gulsuner S, King MC, Parker A, Roosan M, Piccolo SR.
- PLoS One. 2020 Sep 30;15(9):e0239197. doi: 10.1371/journal.pone.0239197.
- PMID: 32997669
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- Impact of mutations in homologous recombination repair genes on treatment outcomes for metastatic castration resistant prostate cancer.
- Carlson AS, Acevedo RI, Lim DM, Gulati R, Gawne A, Sokolova AO, Cheng HH, Nelson PS, Montgomery RB, Yu EY, Schweizer MT.
- PLoS One. 2020 Sep 30;15(9):e0239686. doi: 10.1371/journal.pone.0239686.
- PMID: 32997692
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- Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner.
- Rieckhoff J, Meyer F, Classen S, Zielinski A, Riepen B, Wikman H, Petersen C, Rothkamm K, Borgmann K, Parplys AC.
- Cancers (Basel). 2020 Sep 29;12(10):E2809. doi: 10.3390/cancers12102809.
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- Predicted chemotherapy benefit for breast cancer patients with germline pathogenic variants in cancer susceptibility genes.
- Kurian AW, Ward KC, Abrahamse P, Hamilton AS, Katz SJ.
- JNCI Cancer Spectr. 2020 Sep 18; pkaa083. doi: 10.1093/jncics/pkaa083. eCollection 2020 Sep.
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- Application and reflection of genomic scar assays in evaluating the efficacy of platinum salts and PARP inhibitors in cancer therapy.
- Gou R, Dong H, Lin B.
- Life Sci. 2020 Sep 14:118434. doi: 10.1016/j.lfs.2020.118434. Epub ahead of print.
- PMID: 32941897
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- Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer.
- Muranen TA, Khan S, Fagerholm R, Aittomäki K, Cunningham JM, Dennis J, Leslie G, McGuffog L, Parsons MT, Simard J, Slager S, Soucy P, Easton DF, Tischkowitz M, Spurdle AB, kConFab Investigators, Schmutzler RK, Wappenschmidt B, Hahnen E, Hooning MJ, HEBON Investigators, Singer CF, Wagner G, Thomassen M, Pedersen IS, Domchek SM, Nathanson KL, Lazaro C, Rossing CM, Andrulis IL, Teixeira MR, James P, Garber J, Weitzel JN, SWE-BRCA Investigators, Jakubowska A, Yannoukakos D, John EM, Southey MC, Schmidt MK, Antoniou AC, Chenevix-Trench G, Blomqvist C, Nevanlinna H.
- NPJ Breast Cancer. 2020 Sep 10;6:44. doi: 10.1038/s41523-020-00185-6. eCollection 2020.
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- Hereditary breast cancer: translation into clinical practice of recent American Society of Clinical Oncology, American Society of Radiation Oncology, and Society of Surgical Oncology recommendations.
- Corso G, Magnoni F.
- Eur J Cancer Prev. 2020 Sep 3. doi: 10.1097/CEJ.0000000000000624. Epub ahead of print.
- PMID: 32898012
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- The dawn of targeted therapies for triple negative breast cancer (TNBC): a snapshot of investigational drugs in phase I and II trials.
- Huynh MM, Pambid MR, Jayanthan A, Dorr A, Los G, Dunn SE.
- Expert Opin Investig Drugs. 2020 Sep 1. doi: 10.1080/13543784.2020.1818067. Epub ahead of print.
- PMID: 32869671
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- Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer.
- Huang RSP, Li X, Haberberger J, Sokol E, Severson E, Duncan DL, Hemmerich A, Edgerly C, Ferguson NL, Williams E, Elvin J, Vergilio JA, Killian JK, Lin D, Hiemenz M, Xiao J, McEwan D, Holmes O, Danziger N, Erlich R, Frampton G, Cohen MB, McGregor K, Reddy P, Cardeiro D, Anhorn R, Venstrom PJ, Alexander B, Brown C, Pusztai L, Ross JS, Ramkissoon SH.
- Oncologist. 2020 Sep 1. doi: 10.1634/theoncologist.2020-0449. Epub ahead of print.
- PMID: 32869930
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- Sentinel lymph node biopsy should be considered for clinically node-negative breast cancer regardless of BRCA1/2 mutation status.
- Huang X, Liu JQ, Zhou YD, Xu Y, Chen C, Wang X, Cao X, Yao R, Sun Q.
- Ann Transl Med. 2020 Sep;8(18):1183. doi: 10.21037/atm-20-5996.
- PMID: 33241032
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- Recent advancements in PARP inhibitors-based targeted cancer therapy.
- Zhou P, Wang J, Mishail D, Wang CY.
- Precis Clin Med. 2020 Sep;3(3):187-201. doi: 10.1093/pcmedi/pbaa030. Epub 2020 Aug 31.
- PMID: 32983586
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- Free PMC article
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- Male Breast Cancer in Togo: Imaging and Clinicopathological Findings.
- Darre T, Tchaou M, Djiwa T, Simgban P, Amavi AK, N'Timon B, Amadou A, Bombonne M, Sama B, Amégbor K, Napo-Koura G.
- Int J Breast Cancer. 2020 Aug 31;2020:3056067. doi: 10.1155/2020/3056067.
- PMID: 32934847
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- Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial.
- Diéras V, Han HS, Kaufman B, Wildiers H, Friedlander M, Ayoub JP, Puhalla SL, Bondarenko I, Campone M, Jakobsen EH, Jalving M, Oprean C, Palácová M, Park YH, Shparyk Y, Yañez E, Khandelwal N, Kundu MG, Dudley M, Ratajczak CK, Maag D, Arun BK.
- Lancet Oncol. 2020 Aug 27:S1470-2045(20)30447-2. doi: 10.1016/S1470-2045(20)30447-2. Epub ahead of print.
Comment:
BROCADE3: a challenge to the treatment paradigm in BRCA breast cancer?
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- Combining poly(ADP-ribose) polymerase inhibitors and immune checkpoint inhibitors in breast cancer: rationale and preliminary clinical results.
- Goncalves A, Mezni E, Bertucci F.
- Curr Opin Oncol. 2020 Aug 26. doi: 10.1097/CCO.0000000000000680. Epub ahead of print.
- PMID: 32852311
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- Talazoparib versus chemotherapy in patients with germline BRCA1/2-mutated HER2-negative advanced breast cancer: final overall survival results from the EMBRACA trial.
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