• The Role of Hormonal Replacement Therapy in BRCA Mutated Patients: Lights and Shadows.
    • Loizzi V, Dellino M, Cerbone M, Arezzo F, Cazzato G, Damiani GR, Pinto V, Silvestris E, Kardhashi A, Cicinelli E, Cascardi E, Cormio G.
    • Int J Mol Sci. 2023 Jan 1;24(1):764. doi: 10.3390/ijms24010764.
    • Contraceptives and cancer risks in BRCA1/2 pathogenic variant carriers: a systematic review and meta-analysis.
    • van Bommel MHD, IntHout J, Veldmate G, Kets CM, de Hullu JA, van Altena AM, Harmsen MG.
    • Hum Reprod Update. 2022 Nov 16:dmac038. doi: 10.1093/humupd/dmac038. Epub ahead of print.
    • Reproductive risk factors associated with breast cancer in young women by molecular subtype.
    • Ruddy KJ, Vierkant RA, Jahan N, Higgins A, Partridge A, Larson N, Radisky DC, Couch F, Olson J, Sherman ME.
    • Breast. 2022 Nov 9;66:272-277. doi: 10.1016/j.breast.2022.11.004. Epub ahead of print.
    • Reducing the risk of breast cancer.
    • Pederson HJ, Al-Hilli Z, Kurian AW.
    • Cleve Clin J Med. 2022 Nov 1;89(11):643-652. doi: 10.3949/ccjm.89a.21113.
    • Cancer Effects of Low to Moderate Doses of Ionizing Radiation in Young People with Cancer-Predisposing Conditions: A Systematic Review.
    • Canet M, Harbron R, Thierry-Chef I, Cardis E.
    • Cancer Epidemiol Biomarkers Prev. 2022 Oct 4;31(10):1871-1889. doi: 10.1158/1055-9965.EPI-22-0393.
    • Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C > T Mutation in the Breast Cancer Predisposing Gene PALB2.
    • Courant F, Bougras-Cartron G, Abadie C, Frenel JS, Cartron PF.
    • Epigenomes. 2022 Sep 30;6(4):32. doi: 10.3390/epigenomes6040032.
    • Oral Contraceptive Use and Breast Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Systematic Review and Meta-Analysis of Case–Control Studies.
    • Baranska A, Kanadys W.
    • Cancers (Basel). 2022 Sep 29;14(19):4774. doi: 10.3390/cancers14194774.
    • Breastfeeding reduces the risk of breast cancer: A call for action in high-income countries with low rates of breastfeeding.
    • Stordal B.
    • Cancer Med. 2022 Sep 26. doi: 10.1002/cam4.5288. Epub ahead of print.
    • Association between fertility treatments and breast cancer risk in women with a family history or BRCA mutations: a systematic review and meta-analysis.
    • Liu X, Yue J, Pervaiz R, Zhang H, Wang L.
    • Front Endocrinol (Lausanne). 2022 Sep 13;13:986477. doi: 10.3389/fendo.2022.986477.

    Review registration number: CRD42021281336: The incidence of breast cancer in high risk population after fertility treatment: a systematic review and meta-analysis. (PROSPERO register)

    • Fertility Counseling in BRCA1/2-Mutated Women with Breast Cancer and Healthy Individuals.
    • Kufel-Grabowska J, Podolak A, Maliszewski D, Bartoszkiewicz M, Ramlau R, Lukaszuk K.
    • J Clin Med. 2022 Jul 10;11(14):3996. doi: 10.3390/jcm11143996.
    • Adherence to the 2020 American Cancer Society Guideline for Cancer Prevention and risk of breast cancer for women at increased familial and genetic risk in the Breast Cancer Family Registry: an evaluation of the weight, physical activity, and alcohol consumption recommendations.
    • Geczik AM, Ferris JS, Terry MB, Andrulis IL, Buys SS, Daly MB, Hopper JL, John EM, Kurian AW, Southey MC, Liao Y, Genkinger JM.
    • Breast Cancer Res Treat. 2022 Jul 2. doi: 10.1007/s10549-022-06656-7. Epub ahead of print.
    • Review of the literature on combined oral contraceptives and cancer.
    • Kamani M, Akgor U, Gültekin M.
    • Ecancermedicalscience. 2022 Jun 23;16:1416. doi: 10.3332/ecancer.2022.1416.
    • Physical Activity in Young BRCA Carriers and Reduced Risk of Breast Cancer.
    • Bucy AM, Valencia CI, Howe CL, Larkin TJ, Conard KD, Anderlik EW, Valdivi SI, Bea JW.
    • Am J Prev Med. 2022 Jun 20:S0749-3797(22)00246-X. doi: 10.1016/j.amepre.2022.04.022. Epub ahead of print.
    • Review
    • Environmental Contaminants Modulate Breast Cancer Development and Outcome in TP53 p.R337H Carriers and Noncarriers.
    • Gerber VKQ, Paraizo MM, Ibañez HC, Casali-da-Rocha JC, Pinto EM, Andrade DP, Ibañez MVC, Komechen H, Figueiredo MMO, Custódio G, Fiori CMCM, Balbinotti JHG, Nardin JM, Almeida TA, Beltrame OO, Yamada PA, de Fraga GS, de Brito LL, Martins J, Melanda VS, Licht OAB, Teixeira VZ, Pinho SKS, Bottini S, Lalli E, Zambetti GP, Figueiredo BC.
    • Cancers (Basel). 2022 Jun 19;14(12):3014. doi: 10.3390/cancers14123014.
    • Oral contraceptives and risk of breast cancer and ovarian cancer in women with a BRCA1 or BRCA2 mutation: a meta-analysis of observational studies.
    • Park J, Huang D, Chang YJ, Lim MC, Myung SK.
    • Carcinogenesis. 2022 Apr 25;43(3):231-242. doi: 10.1093/carcin/bgab107.
    • Oral Contraceptive Use in BRCA1 and BRCA2 Mutation Carriers: Absolute Cancer Risks and Benefits.
    • Schrijver LH, Mooij TM, Pijpe A, Sonke GS, Mourits MJE, Andrieu N, Antoniou AC, Easton DF, Engel C, Goldgar D, John EM, Kast K, Milne RL, Olsson H, Phillips KA, Terry MB, Hopper JL, van Leeuwen FE, Rookus MA.
    • J Natl Cancer Inst. 2022 Apr 11;114(4):540-552. doi: 10.1093/jnci/djac004.

    Commentary:

    Oral Contraceptives and BRCA Cancer: A Balancing Act.

    • The Impact of Mediterranean Dietary Intervention on Metabolic and Hormonal Parameters According to BRCA1/2 Variant Type.
    • Oliverio A, Radice P, Colombo M, Paradiso A, Tommasi S, Daniele A, Terribile DA, Magno S, Guarino D, Manoukian S, Peissel B, Bruno E, Pasanisi P.
    • Front Genet. 2022 Mar 9;13:820878. doi: 10.3389/fgene.2022.820878.
    • Weight is More Informative than Body Mass Index for Predicting Postmenopausal Breast Cancer Risk: Prospective Family Study Cohort (ProF-SC).
    • Ye Z, Li S, Dite GS, Nguyen TL, MacInnis RJ, Andrulis IL, Buys SS, Daly MB, John EM, Kurian AW, Genkinger JM, Chung WK, Phillips KA, Thorne H, Winship IM, Milne RL, Dugué PA, Southey MC, Giles GG, Terry MB, Hopper JL.
    • Cancer Prev Res (Phila). 2022 Mar 1;15(3):185-191. doi: 0.1158/1940-6207.CAPR-21-0164.
    • Ovarian stimulation for fertility treatments and risk of breast cancer: a matched cohort study.
    • Machtinger R, Fallach N, Goldstein I, Chodick G, Schiff E, Orvieto R, Mashiach R.
    • Hum Reprod. 2022 Mar 1;37(3):577-585. doi: 10.1093/humrep/deab270.
    • Epidemiologic evidence of exposure to polycyclic aromatic hydrocarbons and breast cancer: A systematic review and meta-analysis.
    • Gamboa-Loira B, López-Carrillo L, Mar-Sánchez Y, Stern D, Cebrián ME.
    • Chemosphere. 2022 Mar;290:133237. doi: 10.1016/j.chemosphere.2021.133237. Epub 2021 Dec 17.
    • Meta-Analysis
    • Lapses in breast cancer screening for highly penetrant mutation carriers during pregnancy and lactation.
    • Chichura A, Hunt J, Lang J, Pederson H.
    • J Surg Oncol. 2022 Mar;125(4):589-595. doi: 10.1002/jso.26761. Epub 2021 Dec 2.
    • Predictors of cardiopulmonary fitness in cancer-affected and -unaffected women with a pathogenic germline variant in the genes BRCA1/2 (LIBRE-1).
    • Berling-Ernst A, Yahiaoui-Doktor M, Kiechle M, Engel C, Lammert J, Grill S, Dukatz R, Rhiem K, Baumann FT, Bischoff SC, Erickson N, Schmidt T, Niederberger U, Siniatchkin M, Halle M.
    • Sci Rep. 2022 Feb 21;12(1):2907. doi: 10.1038/s41598-022-06913-1.
    • Pregnancy after breast cancer in BRCA1/2 mutation carriers.
    • Maksimenko J, Irmejs A, Gardovskis J.
    • Hered Cancer Clin Pract. 2022 Jan 21;20(1):3. doi: 10.1186/s13053-022-00209-1.
    • Healthy lifestyle, genetic risk, and incidence of cancer: A prospective cohort study of 13 cancer types.
    • Byrne S, Boyle T, Ahmed M, Lee SH, Benyamin B, Hyppönen E.
    • medRxiv. 2021 Dec 7. doi: 10.1101/2021.12.07.21267341. Unpublished preprint.

    News: Lifestyle Choices Can Influence Genetic Risks for Cancer. (Medscape Oncology)

    • Physical activity and Mediterranean diet as potential modulators of osteoprotegerin and soluble RANKL in gBRCA1/2 mutation carriers: results of the lifestyle intervention pilot study LIBRE-1.
    • Neirich L, Yahiaoui-Doktor M, Lammert J, Basrai M, Seethaler B, Berling-Ernst A, Ramser J, Quante AS, Schmidt T, Niederberger U, Rhiem K, Schmutzler R, Engel C, Bischoff SC, Halle M, Kiechle M, Grill S.
    • Breast Cancer Res Treat. 2021 Dec;190(3):463-475. doi: 10.1007/s10549-021-06400-7. Epub 2021 Sep 27.
    • Safety of assisted reproductive techniques in young women harboring germline pathogenic variants in BRCA1/2 with a pregnancy after prior history of breast cancer.
    • Condorelli M, Bruzzone M, Ceppi M, Ferrari A, Grinshpun A, Hamy AS, de Azambuja E, Carrasco E, Peccatori FA, Di Meglio A, Paluch-Shimon S, Poorvu PD, Venturelli M, Rousset-Jablonski C, Senechal C, Livraghi L, Ponzone R, De Marchis L, Pogoda K, Sonnenblick A, Villarreal-Garza C, Córdoba O, Teixeira L, Clatot F, Punie K, Graffeo R, Dieci MV, Pérez-Fidalgo JA, Duhoux FP, Puglisi F, Ferreira AR, Blondeaux E, Peretz-Yablonski T, Caron O, Saule C, Ameye L, Balmaña J, Partridge AH, Azim HA, Demeestere I, Lambertini M.
    • ESMO Open. 2021 Dec;6(6):100300. doi: 10.1016/j.esmoop.2021.100300. Epub 2021 Nov 12.
    • Recreational Physical Activity and Outcomes After Breast Cancer in Women at High Familial Risk.
    • Kehm RD, MacInnis RJ, John EM, Liao Y, Kurian AW, Genkinger JM, Knight JA, Colonna SV, Chung WK, Milne R, Zeinomar N, Dite GS, Southey MC, Giles GG, McLachlan SA, Whitaker KD, Friedlander ML, Weideman PC, Glendon G, Nesci S; kConFab Investigators, Phillips KA, Andrulis IL, Buys SS, Daly MB, Hopper JL, Terry MB.
    • JNCI Cancer Spectr. 2021 Dec;5(6):pkab090. doi: 10.1093/jncics/pkab090.
    • Concomitant diagnosis of endometrial and breast cancer - does the sequence matters?
    • Stern T, Peleg Hasson S, Saad A, Levanon K, Michaan N, Laskov I, Wolf I, Safra T.
    • Gynecol Oncol Rep. 2021 Sep 20;38:100863. doi: 10.1016/j.gore.2021.100863. eCollection 2021 Nov.
    • Can harmful lifestyle, obesity and weight changes increase the risk of breast cancer in BRCA 1 and BRCA 2 mutation carriers? A Mini review.
    • Daniele A, Divella R, Pilato B, Tommasi S, Pasanisi P, Patruno M, Digennaro M, Minoia C, Dellino M, Pisconti S, Casamassima P, Savino E, Paradiso AV.
    • Hered Cancer Clin Pract. 2021 Oct 27;19(1):45. doi: 10.1186/s13053-021-00199-6.
    • Biological Role and Clinical Implications of microRNAs in BRCA Mutation Carriers.
    • Tommasi C, Pellegrino B, Boggiani D, Sikokis A, Michiara M, Uliana V, Bortesi B, Bonatti F, Mozzoni P, Pinelli S, Squadrilli A, Viani MV, Cassi D, Maglietta G, Meleti M, Musolino A.
    • Front Oncol. 2021 Sep 6;11:700853. doi: 10.3389/fonc.2021.700853.
    • A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.
    • Marderstein AR, Kulm S, Peng C, Tamimi R, Clark AG, Elemento O.
    • Am J Hum Genet. 2021 Sep 2;108(9):1752-1764. doi: 10.1016/j.ajhg.2021.07.008. Epub 2021 Aug 6.

    News: Breast Cancer Genetic Risk Modified by Corticosteroid Use. (GenomeWeb)

    • A rare case of breast cancer in a transgender woman.
    • Sieberg R, Soriano K, Zuurbier R.
    • Radiol Case Rep. 2021 Aug 26;16(11):3285-3288. doi: 10.1016/j.radcr.2021.07.052.
    • The Effects of Exercise Duration and Intensity on Breast Cancer-Related DNA Methylation: A Randomized Controlled Trial.
    • Gillman AS, Helmuth T, Koljack CE, Hutchison KE, Kohrt WM, Bryan AD.
    • Cancers (Basel). 2021 Aug 17;13(16):4128. doi: 10.3390/cancers13164128.
    • Body mass index and type 2 diabetes and breast cancer survival: a Mendelian randomization study.
    • Liu YS, Wu PE, Chou WC, Vikram R, Chen WT, Yang SL, Bolla MK, Wang Q, Dennis J, Chan TL, Choi JY, Hou MF, Ito H, Kang D, Kim SW, Kwong A, Matsuo K, Park SK, Shu XO, Zheng W, Dunning AM, Easton DF, Shen CY.
    • Am J Cancer Res. 2021 Aug 15;11(8):3921-3934.
    • The impact of risk reducing bilateral salpingo-oophorectomy on sexual function in BRCA1/2 mutation carriers and women with Lynch syndrome: A systematic review and meta-analysis.
    • Kershaw V, Hickey I, Wyld L, Jha S.
    • Eur J Obstet Gynecol Reprod Biol. 2021 Aug 8;265:7-17. doi: 10.1016/j.ejogrb.2021.08.001. Epub ahead of print.
    • Review
    • Diagnostic chest X-rays and breast cancer risk among women with a hereditary predisposition to breast cancer unexplained by a BRCA1 or BRCA2 mutation.
    • Ribeiro Guerra M, Coignard J, Eon-Marchais S, Dondon MG, Le Gal D, Beauvallet J, Mebirouk N, Belotti M, Caron O, Gauthier-Villars M, Coupier I, Buecher B, Lortholary A, Fricker JP, Gesta P, Noguès C, Faivre L, Berthet P, Luporsi E, Delnatte C, Bonadona V, Maugard CM, Pujol P, Lasset C, Longy M, Bignon YJ, Adenis-Lavignasse C, Venat-Bouvet L, Dreyfus H, Gladieff L, Mortemousque I, Audebert-Bellanger S, Soubrier F, Giraud S, Lejeune-Dumoulin S, Limacher JM, Chiesa J, Fajac A, Floquet A, Eisinger F, Tinat J, Fert-Ferrer S, Colas C, Frebourg T, Damiola F, Barjhoux L, Cavaciuti E, Mazoyer S, Tardivon A, Lesueur F, Stoppa-Lyonnet D, Andrieu N.
    • Breast Cancer Res. 2021 Aug 3;23(1):79. doi: 10.1186/s13058-021-01456-1.
    • Interactions Between Adiponectin-Pathway Polymorphisms and Obesity on Postmenopausal Breast Cancer Risk Among African American Women: The WHI SHARe Study.
    • Nam GE, Zhang ZF, Rao J, Zhou H, Jung SY.
    • Front Oncol. 2021 Jul 21;11:698198. doi: 10.3389/fonc.2021.698198.
    • Dose-dependent effects of aerobic exercise on clinically relevant biomarkers among healthy women at high genetic risk for breast cancer: A secondary analysis of a randomized controlled study.
    • Ehret CJ, Zhou S, Tchou JC, Schmitz KH, Sturgeon KM.
    • Cancer Rep (Hoboken). 2021 Jul 9:e1497. doi: 10.1002/cnr2.1497. Epub ahead of print.
    • BRCA, breast cancer and in vitro fertilization: How should we advise our patients?
    • García-Planells J, Francés BS, Diez-Juan A.
    • Fertil Steril. 2021 Jul 8:S0015-0282(21)00505-7. doi: 10.1016/j.fertnstert.2021.06.011. Epub ahead of print.

    Original research:

    Fertility treatments and breast cancer risk in Jewish Israeli BRCA mutation carriers.

    • Blood Arsenic Levels as a Marker of Breast Cancer Risk among BRCA1 Carriers.
    • Marciniak W, Matoušek T, Domchek S, Paradiso A, Patruno M, Irmejs A, Roderte I, Derkacz R, Baszuk P, Kuswik M, Cybulski C, Huzarski T, Gronwald J, Debniak T, Falco M, Lener MR, Jakubowska A, Pullella K, Kotsopoulos J, Narod S, Lubinski J.
    • Cancers (Basel). 2021 Jul 3;13(13):3345. doi: 10.3390/cancers13133345.
    • The impact of body mass index on breast cancer incidence among women at increased risk: an observational study from the International Breast Intervention Studies.
    • Smith SG, Sestak I, Morris MA, Harvie M, Howell A, Forbes J, Cuzick J.
    • Breast Cancer Res Treat. 2021 Jul;188(1):215-223. doi: 10.1007/s10549-021-06141-7. Epub 2021 Mar 3.
    • Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow's Health (CanPath).
    • Pader J, Basmadjian RB, O'Sullivan DE, Mealey NE, Ruan Y, Friedenreich C, Murphy R, Wang E, Quan ML, Brenner DR.
    • Cancer Causes Control. 2021 Jun 25. doi: 10.1007/s10552-021-01460-y. Epub ahead of print.
    • Associations of Plasma Bioactive Adrenomedullin Levels with Cardiovascular Risk Factors in BRCA1/2 Mutation Carriers.
    • Lammert J, Basrai M, Struck J, Hartmann O, Engel C, Bischoff SC, Berling-Ernst A, Halle M, Kiechle M, Grill S.
    • Geburtshilfe Frauenheilkd. 2022 Jun 3;82(6):601-609. doi: 10.1055/a-1811-2164.

    Identifier: NCT02087592: Feasibility of Lifestyle Intervention in BRCA1/2 Mutation Carriers (LIBRE). (ClinicalTrials.gov)

    Identifier: NCT02516540: Efficacy of Lifestyle Intervention in BRCA1/2 Mutation Carriers (LIBRE-2). (ClinicalTrials.gov)

    • An evaluation of memory and attention in BRCA mutation carriers using an online cognitive assessment tool.
    • Kotsopoulos J, Kim SJ, Armel S, Bordeleau L, Foulkes WD, McKinnon W, Panchal S, Cohen SA, Sun S, Sun P, McKetton L, Troyer AK, Narod SA.
    • Cancer. 2021 Jun 2. doi: 10.1002/cncr.33654. Epub ahead of print.
    • The impact of high-intensity interval exercise training on NK-cell function and circulating myokines for breast cancer prevention among women at high risk for breast cancer.
    • Coletta AM, Agha NH, Baker FL, Niemiro GM, Mylabathula PL, Brewster AM, Bevers TB, Fuentes-Mattei E, Basen-Engquist K, Gilchrist SC, Simpson RJ.
    • Breast Cancer Res Treat. 2021 Jun;187(2):407-416. doi: 10.1007/s10549-021-06111-z. Epub 2021 Feb 8.

    Identifier: NCT02923401: High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer. (ClinicalTrials.gov)

    • Lifestyle Characteristics in Women Carriers of BRCA Mutations: Results From an Italian Trial Cohort.
    • Bruno E, Oliverio A, Paradiso A, Daniele A, Tommasi S, Terribile DA, Filippone A, Digennaro M, Pilato B, Danza K, Guarino D, Rossi C, Rossi MM, Venturelli E, Giussani M, Peissel B, Pasanisi P.
    • Clin Breast Cancer. 2021 Jun;21(3):e168-e176. doi: 10.1016/j.clbc.2020.11.002. Epub 2020 Nov 10.
    • Germline mutations in a clinic-based series of pregnancy associated breast cancer patients.
    • Zografos E, Korakiti AM, Andrikopoulou A, Rellias I, Dimitrakakis C, Marinopoulos S, Giannos A, Keramopoulos A, Bredakis N, Dimopoulos MA, Zagouri F.
    • BMC Cancer. 2021 May 19;21(1):572. doi: 10.1186/s12885-021-08310-9.
    • Hormone Replacement Therapy After Gynaecological Malignancies: a Review Article.
    • Sourouni M, Kiesel L.
    • Geburtshilfe Frauenheilkd. 2021 May;81(5):549-554. doi: 10.1055/a-1390-4353. Epub 2021 May 20.
    • Hormone replacement therapy in BRCA mutation carriers and risk of ovarian, endometrial, and breast cancer: a systematic review.
    • Huber D, Seitz S, Kast K, Emons G, Ortmann O.
    • J Cancer Res Clin Oncol. 2021 Apr 22. doi: 10.1007/s00432-021-03629-z. Epub ahead of print.
    • Fertility treatments and breast cancer risk in Jewish Israeli BRCA mutation carriers.
    • Perri T, Naor-Revel S, Eliassi-Revivo P, Lifshitz D, Friedman E, Korach J.
    • Fertil Steril. 2021 Apr 3:S0015-0282(21)00148-5. doi: 10.1016/j.fertnstert.2021.02.030. Epub ahead of print.

    Commentary:

    BRCA, breast cancer and in vitro fertilization: How should we advise our patients?

    • Breast cancer risk and hormone replacement therapy among BRCA carriers after risk-reducing salpingo-oophorectomy.
    • Michaelson-Cohen R, Gabizon-Peretz S, Armon S, Srebnik-Moshe N, Mor P, Tomer A, Levy-Lahad E, Paluch-Shimon S.
    • Eur J Cancer. 2021 Mar 16;148:95-102. doi: 10.1016/j.ejca.2021.02.007. Epub ahead of print.
    • VTRNA2-1: Genetic Variation, Heritable Methylation and Disease Association.
    • Dugué PA, Yu C, McKay T, Wong EM, Joo JE, Tsimiklis H, Hammet F, Mahmoodi M, Theys D, kConFab, Hopper JL, Giles GG, Milne RL, Steen JA, Dowty JG, Nguyen-Dumont T, Southey MC.
    • Int J Mol Sci. 2021 Mar 3;22(5):2535. doi: 10.3390/ijms22052535.
    • Effects of obesity on breast aromatase expression and systemic metabo-inflammation in women with BRCA1 or BRCA2 mutations.
    • Iyengar NM, Zhou XK, Mendieta H, El-Hely O, Giri DD, Winston L, Falcone DJ, Wang H, Meng L, Ha T, Pollak M, Morrow M, Dannenberg AJ.
    • NPJ Breast Cancer. 2021 Mar 1;7(1):18. doi: 10.1038/s41523-021-00226-8.
    • Fertility preservation in patients with BRCA mutations or Lynch syndrome.
    • Corrado G, Marchetti C, Trozzi R, Scambia G, Fagotti A.
    • Int J Gynecol Cancer. 2021 Mar;31(3):332-338. doi: 10.1136/ijgc-2020-002071.

    Letter:

    Should we or should we not? Risk reduction bilateral salpingectomy for BRCA mutation carriers.

    Letter, Reply:

    Response to: Should we or should we not? Risk reduction bilateral salpingectomy for BRCA mutation carriers.

    • Lifestyle, behavioral, and dietary risk factors in relation to mammographic breast density in women at high risk for breast cancer.
    • Ahern TP, Sprague BL, Farina NH, Tsai E, Cuke M, Kontos D, Wood ME.
    • Cancer Epidemiol Biomarkers Prev. 2021 Feb 22:cebp.1567.2020. doi: 10.1158/1055-9965.EPI-20-1567. Epub ahead of print.
    • Precursor fractions of neurotensin and enkephalin might point to molecular mechanisms of cancer risk modulation during a lifestyle-intervention in germline BRCA1/2 gene mutation carriers.
    • Grill S, Yahiaoui-Doktor M, Basrai M, Struck J, Schulte J, Berling-Ernst A, Engel C, Ullrich M, Lammert J, Bischoff SC, Schmidt T, Niederberger U, Chronas D, Rhiem K, Schmutzler R, Halle M, Kiechle M.
    • Breast Cancer Res Treat. 2021 Feb 4. doi: 10.1007/s10549-020-06070-x. Epub ahead of print.
    • Study: Breastfeeding may lower risk of ovarian cancer in women with BRCA mutations.
    • [No author given]
    • FORCE. XRAY. 2021 Jan 28.

    Original research:

    Hereditary Ovarian Cancer Clinical Study Group. Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation.

    Blog post: Did Breastfeeding my Daughter Reduce my Ovarian Cancer Risk? (FORCE. Blog.)

    • Coffee consumption and breast cancer risk: a narrative review in the general population and in different subtypes of breast cancer.
    • Nehlig A, Reix N, Arbogast P, Mathelin C.
    • Eur J Nutr. 2021 Jan 13. doi: 10.1007/s00394-020-02465-0. Epub ahead of print.
    • Review
    • The Relationship Between GSTT1, GSTM1, GSTO1, GSTP1 and MTHFR Gene Polymorphisms and DNA Damage of BRCA1 and BRCA2 Genes in Arsenic-Exposed Workers.
    • Qian S, Tan J, Zhou Q, Yin J, Li H, He Y.
    • J Occup Environ Med. 2021 Jan 12. doi: 10.1097/JOM.0000000000002142. Epub ahead of print.
    • Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers.
    • Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2021 Jan 10. doi: 10.1007/s10549-020-06072-9. Epub ahead of print.
    • In Response to "Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations".
    • Narod SA, Giannakeas V.
    • J Clin Oncol. 2020 Dec 20;38(36):4352. doi: 10.1200/JCO.20.02253. Epub 2020 Oct 30.

    Letter, Comment:

    Reply to S. A. Narod et al.

    Original research:

    Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations.

    • A Mediterranean Dietary Intervention in Female Carriers of BRCA Mutations: Results from an Italian Prospective Randomized Controlled Trial.
    • Bruno E, Oliverio A, Paradiso AV, Daniele A, Tommasi S, Tufaro A, Terribile DA, Magno S, Filippone A, Venturelli E, Morelli D, Baldassari I, Cravana ML, Manoukian S, Pasanisi P.
    • Cancers (Basel). 2020 Dec 11;12(12):3732. doi: 10.3390/cancers12123732.
    • Impact of ARTs on oncological outcomes in young breast cancer survivors.
    • Condorelli M, De Vos M, Lie Fong S, Autin C, Delvigne A, Vanden Meerschaut F, Wyns C, Imbert R, Cheruy C, Bouziotis J, de Azambuja E, Delbaere A, Lambertini M, Demeestere I.
    • Hum Reprod. 2020 Dec 8:deaa319. doi: 10.1093/humrep/deaa319. Epub ahead of print.
    • Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation.
    • Kotsopoulos J, Gronwald J, McCuaig JM, Karlan BY, Eisen A, Tung N, Bordeleau L, Senter L, Eng C, Couch F, Fruscio R, Weitzel JN, Olopade O, Singer CF, Pal T, Foulkes WD, Neuhausen SL, Sun P, Lubinski J, Narod SA; Hereditary Ovarian Cancer Clinical Study Group.
    • Gynecol Oncol. 2020 Dec;159(3):820-826. doi: 10.1016/j.ygyno.2020.09.037. Epub 2020 Sep 30.

    Research news: Study: Breastfeeding may lower risk of ovarian cancer in women with BRCA mutations. (FORCE. XRAY.)

    Blog post: Did Breastfeeding my Daughter Reduce my Ovarian Cancer Risk? (FORCE. Blog.)

    • BRCA1/2 Variants and Metabolic Factors: Results From a Cohort of Italian Female Carriers.
    • Oliverio A, Bruno E, Colombo M, Paradiso A, Tommasi S, Daniele A, Terribile DA, Magno S, Guarino D, Manoukian S, Peissel B, Radice P, Pasanisi P.
    • Cancers (Basel). 2020 Nov 30;12(12):3584. doi: 10.3390/cancers12123584.
    • Isoflavone intake on the risk of overall breast cancer and molecular subtypes in women at high risk for hereditary breast cancer.
    • Sim EJ, Ko KP, Ahn C, Park SM, Surh YJ, An S, Kim SW, Lee MH, Lee JW, Lee JE, Kim KS, Yom CK, Kim HA, Park SK.
    • Breast Cancer Res Treat. 2020 Nov;184(2):615-626. doi: 10.1007/s10549-020-05875-0. Epub 2020 Oct 17.
    • Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations.
    • Lambertini M, Ameye L, Hamy AS, Zingarello A, Poorvu PD, Carrasco E, Grinshpun A, Han S, Rousset-Jablonski C, Ferrari A, Paluch-Shimon S, Cortesi L, Senechal C, Miolo G, Pogoda K, Pérez-Fidalgo JA, De Marchis L, Ponzone R, Livraghi L, Estevez-Diz MDP, Villarreal-Garza C, Dieci MV, Clatot F, Berlière M, Graffeo R, Teixeira L, Córdoba O, Sonnenblick A, Luna Pais H, Ignatiadis M, Paesmans M, Partridge AH, Caron O, Saule C, Del Mastro L, Peccatori FA, Azim HA Jr.
    • J Clin Oncol. 2020 Sep 10;38(26):3012-3023. doi: 10.1200/JCO.19.02399. Epub 2020 Jul 16.

    Letter, Commentary:

    In Response to "Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations".

    Letter, Commentary:

    Reply to S. A. Narod et al.

    • Disparities in Genetic Testing and Care among Black women with Hereditary Breast Cancer.
    • Reid S, Cadiz S, Pal T.
    • Curr Breast Cancer Rep. 2020 Sep;12(3):125-131. doi: 10.1007/s12609-020-00364-1. Epub 2020 May 19.
    • Use of fertility treatments in BRCA1/2 mutation carriers and risk for ovarian and breast cancer: a systematic review.
    • Huber D, Seitz S, Kast K, Emons G, Ortmann O.
    • Arch Gynecol Obstet. 2020 Jul 27. doi: 10.1007/s00404-020-05690-4. Epub ahead of print.
    • Lifestyle Choices May Reduce Breast Cancer Risk Regardless of Genetics.
    • Otto MA.
    • Medscape. 2020 Jul 7.

    Original research:

    Association of Nongenetic Factors With Breast Cancer Risk in Genetically Predisposed Groups of Women in the UK Biobank Cohort.

    Research news: Lifestyle choices may reduce breast cancer risk regardless of genetics. (MDedge | Hematology & Oncology)

    • Beneficial Molecular Adaptations In BRCA-Mutation Carriers By Combined HIT/HIRT Intervention: Results From A Pilot Study.
    • Bizjak DA, Schulz SVW, Schumann U, Otto S, Kirsten J, Ebner F, Leinert E, Huober J, Janni W, Steinacker JM.
    • Cancers (Basel). 2020 Jun 10;12(6):E1526. doi: 10.3390/cancers12061526.
    • Comparison of breast cancer incidence, clinicopathologic features, and risk factor prevalence in women aged 20-29 at diagnosis to those aged 30-39.
    • Limbach KE, Leon E, Pommier RF, Pommier SJ.
    • Breast J. 2020 May;26(5):1069-1070. doi: 10.1111/tbj.13783. Epub 2020 Feb 14.
    • Association of Nongenetic Factors With Breast Cancer Risk in Genetically Predisposed Groups of Women in the UK Biobank Cohort.
    • Al Ajmi K, Lophatananon A, Mekli K, Ollier W, Muir KR.
    • JAMA Netw Open. 2020 Apr 1;3(4):e203760. doi: 10.1001/jamanetworkopen.2020.3760.
    • Diet, weight management, physical activity and Ovarian & Breast Cancer Risk in women with BRCA1/2 pathogenic Germline gene variants: systematic review.
    • Coletta AM, Peterson SK, Gatus LA, Krause KJ, Schembre SM, Gilchrist SC, Arun B, You YN, Rodriguez-Bigas MA, Strong LL, Lu KH, Basen-Engquist K.
    • Hered Cancer Clin Pract. 2020 Mar 7;18:5. doi: 10.1186/s13053-020-0137-1. eCollection 2020.
    • Use of oral contraceptives in BRCA mutation carriers and risk for ovarian and breast cancer: a systematic review.
    • Huber D, Seitz S, Kast K, Emons G, Ortmann O.
    • Arch Gynecol Obstet. 2020 Mar 5. doi: 10.1007/s00404-020-05458-w. [Epub ahead of print]
    • Review
    • A retrospective study on breast cancer presentation, risk factors, and protective factors in patients with a positive family history of breast cancer.
    • Liaw YY, Loong FS, Tan S, On SY, Khaw E, Chiew Y, Nordin R, Mat TN, Arulanantham S, Gandhi A.
    • Breast J. 2020 Mar;26(3):469-473. doi: 10.1111/tbj.13520. Epub 2019 Sep 4.
    • Genetic factors, adherence to healthy lifestyle behavior, and risk of invasive breast cancer among women in the UK Biobank.
    • Arthur RS, Wang T, Xue X, Kamensky V, Rohan TE.
    • J Natl Cancer Inst. 2020 Jan 3. pii: djz241. doi: 10.1093/jnci/djz241. [Epub ahead of print]
    • Recreational Physical Activity Is Associated with Reduced Breast Cancer Risk in Adult Women at High Risk for Breast Cancer: A Cohort Study of Women Selected for Familial and Genetic Risk.
    • Kehm RD, Genkinger JM, MacInnis RJ, John EM, Phillips KA, Dite GS, Milne RL, Zeinomar N, Liao Y, Knight JA, Southey MC, Chung WK, Giles GG, McLachlan SA, Whitaker KD, Friedlander M, Weideman PC, Glendon G, Nesci S, Investigators K, Andrulis IL, Buys SS, Daly MB, Hopper JL, Terry MB.
    • Cancer Res. 2020 Jan 1;80(1):116-125. doi: 10.1158/0008-5472.CAN-19-1847. Epub 2019 Oct 2.

    Commentary:

    Physical Activity and Breast Cancer: Focusing on High-Risk Subgroups and Putting Recommendations in Context.

    Research news: Study: Women who exercise have lower breast cancer risk whether or not they have a family history of breast cancer. (FORCE. XRAYS.)

    • Tea consumption and breast cancer risk in a cohort of women with family history of breast cancer.
    • Zhang D, Nichols HB, Troester M, Cai J, Bensen JT, Sandler DP.
    • Int J Cancer. 2019 Dec 13. doi: 10.1002/ijc.32824. [Epub ahead of print]
    • Study: Women who exercise have lower breast cancer risk whether or not they have a family history of breast cancer.
    • [No author given.]
    • FORCE. XRAYS. 2019 Dec 6.

    Original research:

    Recreational physical activity is associated with reduced breast cancer risk in adult women at high risk for breast cancer: a cohort study of women selected for familial and genetic risk.

    • Alcohol consumption, cigarette smoking, and risk of breast cancer for BRCA1 and BRCA2 mutation carriers: results from The BRCA1 and BRCA2 Cohort Consortium.
    • Li H, Terry MB, Antoniou AC, Phillips KA, Kast K, Mooij TM, Engel C, Noguès C, Stoppa-Lyonnet D, Lasset C, Berthet P, Mari V, Caron O, Barrowdale D, Frost D, Brewer C, Evans DG, Izatt L, Side L, Walker L, Tischkowitz M, Rogers MT, Porteous ME, Meijers-Heijboer HEJ, Gille JJ, Blok MJ, Hoogerbrugge N, Daly MB, Andrulis IL, Buys SS, John EM, McLachlan SA, Friedlander M, Tan YY, Osorio A, Caldes T, Jakubowska A, Simard J, Singer CF, Olah E, Navratilova M, Foretova L, Gerdes AM, Roos-Blom MJ, Arver B, Olsson H, Schmutzler RK, Hopper JL, Milne RL, Easton DF, Van Leeuwen FE, Rookus MA, Andrieu N, Goldgar DE.
    • Cancer Epidemiol Biomarkers Prev. 2019 Dec 2. pii: cebp.0546.2019. doi: 10.1158/1055-9965.EPI-19-0546. [Epub ahead of print]
    • Paraben Content in Adjacent Normal-malignant Breast Tissues from Women with Breast Cancer.
    • Amin MM, Tabatabaeian M, Chavoshani A, Amjadi E, Hashemi M, Ebrahimpour K, Klishadi R, Khazaei S, Mansourian M.
    • Biomed Environ Sci. 2019 Dec;32(12):893-904. doi: 10.3967/bes2019.112.
    • The contribution of breastfeeding to the prevention of breast cancer.
    • Dimou S, Mamakou A, Konstantaki E, Spanou M.
    • Eur J Midwifery. 2019 Nov 29;3:21. doi: 10.18332/ejm/114885.
    • Alcohol consumption, cigarette smoking, and familial breast cancer risk: findings from the Prospective Family Study Cohort (ProF-SC).
    • Zeinomar N, Knight JA, Genkinger JM, Phillips KA, Daly MB, Milne RL, Dite GS, Kehm RD, Liao Y, Southey MC, Chung WK, Giles GG, McLachlan SA, Friedlander ML, Weideman PC, Glendon G, Nesci S; kConFab Investigators, Andrulis IL, Buys SS, John EM, MacInnis RJ, Hopper JL, Terry MB.
    • Breast Cancer Res. 2019 Nov 28;21(1):128. doi: 10.1186/s13058-019-1213-1.
    • Synergistic Effect Between Full-Term Pregnancy/Breastfeeding And Familial Susceptibility On Breast Cancer Risk.
    • Lin H, Wen J, Hong L, Chen Y, Wu Y, Zhong S.
    • Cancer Manag Res. 2019 Nov 15;11:9743-9748. doi: 10.2147/CMAR.S231426. eCollection 2019.
    • Fatty acid profiles in erythrocyte membranes following the Mediterranean diet - data from a multicenter lifestyle intervention study in women with hereditary breast cancer (LIBRE).
    • Seethaler B, Basrai M, Vetter W, Lehnert K, Engel C, Siniatchkin M, Halle M, Kiechle M, Bischoff SC.
    • Clin Nutr. 2019 Nov 2. pii: S0261-5614(19)33126-7. doi: 10.1016/j.clnu.2019.10.033. [Epub ahead of print]
    • Sexual function, menopausal symptoms, depression and cancer worry in women with BRCA mutations.
    • Powell CB, Alabaster A, Le A, Stoller N, Armstrong MA, Raine-Bennett T.
    • Psychooncology. 2019 Oct 26. doi: 10.1002/pon.5253. [Epub ahead of print]
    • Reproductive and hormonal considerations in women at increased risk for hereditary gynecologic cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review.
    • Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T.
    • Fertil Steril. 2019 Oct 3. pii: S0015-0282(19)31982-X. doi: 10.1016/j.fertnstert.2019.07.1349. [Epub ahead of print]
    • Review
    • Is it safe for BRCA mutation carriers to become pregnant following breast cancer?
    • [No author given]
    • FORCE. XRAYS. 2019 Sep 4.
    • Reproductive and Hormonal Considerations in Women at Increased Risk for Hereditary Gynecologic Cancers: Society of Gynecologic Oncology and American Society for Reproductive Medicine Evidence-Based Review.
    • Chen LM, Blank SV, Burton E, Glass K, Penick E, Woodard T.
    • Gynecol Oncol. 2019 Aug 22. pii: S0090-8258(19)31333-2. doi: 10.1016/j.ygyno.2019.06.017. [Epub ahead of print]
    • Review
    • Prediagnosis aspirin use, DNA methylation, and mortality after breast cancer: A population-based study.
    • Wang T, McCullough LE, White AJ, Bradshaw PT, Xu X, Cho YH, Terry MB, Teitelbaum SL, Neugut AI, Santella RM, Chen J, Gammon MD.
    • Cancer. 2019 Aug 12. doi: 10.1002/cncr.32364. [Epub ahead of print]
    • BRCA1 and BRCA2 Gene Expression: Diurnal Variability and Influence of Shift Work.
    • Bracci M, Ciarapica V, Zabaleta ME, Tartaglione MF, Pirozzi S, Giuliani L, Piva F, Valentino M, Ledda C, Rapisarda V, Stevens RG, Santarelli L.
    • Cancers (Basel). 2019 Aug 9;11(8). pii: E1146. doi: 10.3390/cancers11081146.
    • Response to Lee et al 2019: Essential to frame study implications within the context of prior findings from enriched cohorts for underlying familial risk of breast cancer.
    • Terry MB, Zeinomar N.
    • Occup Environ Med. 2019 Aug;76(8):592. doi: 10.1136/oemed-2019-105936.
    • Letter, Comment

    Original research:

    Women's occupational exposure to polycyclic aromatic hydrocarbons and risk of breast cancer.

    • Combined hormonal contraceptives in BRCA gene mutation carriers: why not?
    • Grandi G, Sammarini M, Chiara Del Savio M, Toss A, Facchinetti F.
    • Eur J Contracept Reprod Health Care. 2019 Jul 30:1-3. doi: 10.1080/13625187.2019.1647335. [Epub ahead of print]
    • Night Shift Work, DNA Methylation and Telomere Length: An Investigation on Hospital Female Nurses.
    • Carugno M, Maggioni C, Crespi E, Bonzini M, Cuocina S, Dioni L, Tarantini L, Consonni D, Ferrari L, Pesatori AC.
    • Int J Environ Res Public Health. 2019 Jun 28;16(13). pii: E2292. doi: 10.3390/ijerph16132292.
    • Predictors of mammographic density among women with a strong family history of breast cancer.
    • Moran O, Eisen A, Demsky R, Blackmore K, Knight JA, Panchal S, Ginsburg O, Zbuk K, Yaffe M, Metcalfe KA, Narod SA, Kotsopoulos J.
    • BMC Cancer. 2019 Jun 26;19(1):631. doi: 10.1186/s12885-019-5855-2.
    • Reproductive factors associated with breast cancer risk in Li-Fraumeni syndrome.
    • Khincha PP, Best AF, Fraumeni JF Jr, Loud JT, Savage SA, Achatz MI.
    • Eur J Cancer. 2019 Jun 15;116:199-206. doi: 10.1016/j.ejca.2019.05.005. [Epub ahead of print]
    • How Safe Is Hormone Replacement Therapy After Risk-Reducing Salpingo-oophorectomy in Women With BRCA Mutations?
    • Markman M.
    • Medscape Oncology. 2019 Jun 14.

    Original research:

    Hormone replacement therapy after risk reducing salpingo-oophorectomy in patients with BRCA1 or BRCA2 mutations; a systematic review of risks and benefits.

    • Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D in Premenopausal Women at High Risk for Breast Cancer (SWOG S0812).
    • Crew KD, Anderson GL, Hershman DL, Terry MB, Tehranifar P, Lew DL, Yee M, Brown EA, Kairouz SS, Kuwajerwala N, Bevers TB, Doster JE, Zarwan C, Kruper L, Minasian L, Ford LG, Arun BK, Neuhouser ML, Goodman GE, Brown PH.
    • Cancer Prev Res (Phila). 2019 May 28. pii: canprevres.0444.2018. doi: 10.1158/1940-6207.CAPR-18-0444. [Epub ahead of print]
    • Breast Cancer Susceptibility—Towards Individualised Risk Prediction.
    • Lakeman IMM, Schmidt MK, van Asperen CJ, Devilee P.
    • Curr Genet Med Rep. 2019 May 17. doi: 10.1007/s40142-019-00168-5. [Epub ahead of print]
    • Do Vitamin B supplements alter breast cancer risk for women with BRCA mutations?
    • [No author given]
    • FORCE. XRAYS. 2019 May 17.

    Original research:

    Folic acid supplement use and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a case-control study.

    • The influence of reproductive factors on breast cancer risk in women with pathogenic mutations.
    • Gabriel Goidescu I, Caracostea G, Rotar IC, Eniu DT, Nemeti GI, Cruciat G, Stamatian F, Muresan D.
    • J BUON. 2019 May-Jun;24(3):1067-1074.
    • Breast cancer risk associated with BRCA1/2 variants in the Pakistani population.
    • Abbas S, Siddique A, Shahid N, Khan RT, Fatima W.
    • Breast Cancer. 2019 May;26(3):365-372. doi: 10.1007/s12282-018-0932-y. Epub 2018 Nov 14.
    • Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study.
    • Kehm RD, Hopper JL, John EM, Phillips KA, MacInnis RJ, Dite GS, Milne RL, Liao Y, Zeinomar N, Knight JA, Southey MC, Vahdat L, Kornhauser N, Cigler T, Chung WK, Giles GG, McLachlan SA, Friedlander ML, Weideman PC, Glendon G, Nesci S, kConFab Investigators, Andrulis IL, Buys SS, Daly MB, Terry MB.
    • Breast Cancer Res. 2019 Apr 18;21(1):52. doi: 10.1186/s13058-019-1135-y.
    • Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study.
    • Qian F, Wang S, Mitchell J, McGuffog L, Barrowdale D, Leslie G, Oosterwijk JC, Chung WK, Evans DG, Engel C, Kast K, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Arun BK, Ausems MGEM, Azzollini J, Barouk-Simonet E, Barwell J, Belotti M, Benitez J, Berger A, Borg A, Bradbury AR, Brunet J, Buys SS, Caldes T, Caligo MA, Campbell I, Caputo SM, Chiquette J, Claes KBM, Margriet Collée J, Couch FJ, Coupier I, Daly MB, Davidson R, Diez O, Domchek SM, Donaldson A, Dorfling CM, Eeles R, Feliubadaló L, Foretova L, Fowler J, Friedman E, Frost D, Ganz PA, Garber J, Garcia-Barberan V, Glendon G, Godwin AK, Gómez Garcia EB, Gronwald J, Hahnen E, Hamann U, Henderson A, Hendricks CB, Hopper JL, Hulick PJ, Imyanitov EN, Isaacs C, Izatt L, Izquierdo Á, Jakubowska A, Kaczmarek K, Kang E, Karlan BY, Kets CM, Kim SW, Kim Z, Kwong A, Laitman Y, Lasset C, Hyuk Lee M, Won Lee J, Lee J, Lester J, Lesueur F, Loud JT, Lubinski J, Mebirouk N, Meijers-Heijboer HEJ, Meindl A, Miller A, Montagna M, Mooij TM, Morrison PJ, Mouret-Fourme E, Nathanson KL, Neuhausen SL, Nevanlinna H, Niederacher D, Nielsen FC, Nussbaum RL, Offit K, Olah E, Ong KR, Ottini L, Park SK, Peterlongo P, Pfeiler G, Phelan CM, Poppe B, Pradhan N, Radice P, Ramus SJ, Rantala J, Robson M, Rodriguez GC, Schmutzler RK, Hutten Selkirk CG, Shah PD, Simard J, Singer CF, Sokolowska J, Stoppa-Lyonnet D, Sutter C, Yen Tan Y, Teixeira RM, Teo SH, Terry MB, Thomassen M, Tischkowitz M, Toland AE, Tucker KM, Tung N, van Asperen CJ, van Engelen K, van Rensburg EJ, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Yannoukakos D; GEMO Study Collaborators; HEBON; EMBRACE, Greene MH, Rookus MA, Easton DF, Chenevix-Trench G, Antoniou AC, Goldgar DE, Olopade OI, Rebbeck TR, Huo D.
    • J Natl Cancer Inst. 2019 Apr 1;111(4):350-364. doi: 10.1093/jnci/djy132.
    • Folic acid supplement use and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a case-control study.
    • Kim SJ, Zhang CXW, Demsky R, Armel S, Kim YI, Narod SA, Kotsopoulos J.
    • Breast Cancer Res Treat. 2019 Apr;174(3):741-748. doi: 10.1007/s10549-018-05118-3. Epub 2019 Jan 2.

    Research news: Do Vitamin B supplements alter breast cancer risk for women with BRCA mutations? (FORCE. XRAYS.)

    • Hormone replacement therapy after risk reducing salpingo-oophorectomy in patients with BRCA1 or BRCA2
    • Gordhandas S, Norquist BM, Pennington KP, Yung RL, Laya MB, Swisher EM.
    • Gynecol Oncol. 2019 Apr;153(1):192-200. doi: 10.1016/j.ygyno.2018.12.014. Epub 2019 Jan 17.
    • Review

    Commentary: How Safe Is Hormone Replacement Therapy After Risk-Reducing Salpingo-oophorectomy in Women With BRCA Mutations? (Medscape Oncology)

    • The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With BRCA1 or BRCA2 Mutations.
    • Terry MB, Liao Y, Kast K, Antoniou AC, McDonald JA, Mooij TM Engel C, Nogues C Buecher B, Mari V, Moretta-Serra J, Gladieff L, Luporsi E, Barrowdale D, Frost D, Henderson A, Brewer C, Evans DG, Eccles D, Cook J, Ong K, Izatt L, Ahmed M, Morrison PJ, Dommering CJ, Oosterwijk JC, Ausems MGEM, Kriege M, Buys SS, Andrulis IL, John EM, Daly M, Friedlander M, McLachlan SA, Osorio A, Caldes T, Jakubowska A, Simard J, Singer CF, Tan Y, Olah E, Navratilova M, Foretova L, Gerdes AM, Roos-Blom MJ, Arver B, Olsson H, Schmutzler RK, Hopper JL, van Leeuwen FE, Goldgar D, Milne RL, Easton DF, Rookus MA, Andrieu N.
    • JNCI Cancer Spectrum. 2018 Nov 1 [Published 2019 Mar 8];2(4):pky078. doi: 10.1093/jncics/pky078.
    • Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
    • Deli T, Orosz M, Jakab A.
    • Pathol Oncol Res. 2019 Jan 8. doi: 10.1007/s12253-018-00569-x. [Epub ahead of print]
    • Breast Cancer Risk After Recent Childbirth: A Pooled Analysis of 15 Prospective Studies.
    • Nichols HB, Schoemaker MJ, Cai J, Xu J, Wright LB, Brook MN, Jones ME, Adami HO, Baglietto L, Bertrand KA, Blot WJ, Boutron-Ruault MC, Dorronsoro M, Dossus L, Eliassen AH, Giles GG, Gram IT, Hankinson SE, Hoffman-Bolton J, Kaaks R, Key TJ, Kitahara CM, Larsson SC, Linet M, Merritt MA, Milne RL, Pala V, Palmer JR, Peeters PH, Riboli E, Sund M, Tamimi RM, Tjønneland A, Trichopoulou A, Ursin G, Vatten L, Visvanathan K, Weiderpass E, Wolk A, Zheng W, Weinberg CR, Swerdlow AJ, Sandler DP.
    • Ann Intern Med. 2019 Jan 1;170(1):22-30. doi: 10.7326/M18-1323. Epub 2018 Dec 11.

    Editorial, Comment:

    Learning From Temporal Relationships: Childbirth and Breast Cancer Risk.

    Research news: Breast cancer risk increases modestly after childbirth. (FORCE. XRAYS.)

    • Adult Physical Activity and Breast Cancer Risk in Women with a Family History of Breast Cancer.
    • Niehoff NM, Nichols HB, Zhao S, White AJ, Sandler DP.
    • Cancer Epidemiol Biomarkers Prev. 2019 Jan;28(1):51-58. doi: 10.1158/1055-9965.EPI-18-0674. Epub 2018 Oct 17.
    • Preventative Health and Risk Behaviors Among Adolescent Girls With and Without Family Histories of Breast Cancer.
    • Schwartz LA, Henry-Moss D, Egleston B, Patrick-Miller L, Markman E, Daly M, Tuchman L, Moore C, Rauch PK, Karpink K, Sands CB, Domchek SM, Bradbury AR.
    • J Adolesc Health. 2019 Jan;64(1):116-123. doi: 10.1016/j.jadohealth.2018.07.011. Epub 2018 Oct 6.
    • Women's occupational exposure to polycyclic aromatic hydrocarbons and risk of breast cancer.
    • Lee DG, Burstyn I, Lai AS, Grundy A, Friesen MC, Aronson KJ, Spinelli JJ.
    • Occup Environ Med. 2019 Jan;76(1):22-29. doi: 10.1136/oemed-2018-105261.

    Letter, Comment:

    Response to Lee et al 2019: Essential to frame study implications within the context of prior findings from enriched cohorts for underlying familial risk of breast cancer.

    • Age-specific breast cancer risk by body mass index and familial risk: prospective family study cohort (ProF-SC).
    • Hopper JL, Dite GS, MacInnis RJ, Liao Y, Zeinomar N, Knight JA, Southey MC, Milne RL, Chung WK, Giles GG, Genkinger JM, McLachlan SA, Friedlander ML, Antoniou AC, Weideman PC, Glendon G, Nesci S; kConFab Investigators, Andrulis IL, Buys SS, Daly MB, John EM, Phillips KA, Terry MB.
    • Breast Cancer Res. 2018 Nov 3;20(1):132. doi: 10.1186/s13058-018-1056-1.
    • Physical Activity, Global DNA Methylation, and Breast Cancer Risk: A Systematic Literature Review and Meta-analysis.
    • Boyne DJ, O'Sullivan DE, Olij BF, King WD, Friedenreich CM, Brenner DR.
    • Cancer Epidemiol Biomarkers Prev. 2018 Nov;27(11):1320-1331. doi: 10.1158/1055-9965.EPI-18-0175. Epub 2018 Jul 10.
    • Review
    • Hormonal contraceptives and breast cancer: Clinical data.
    • Zolfaroli I, Tarín JJ, Cano A.
    • Eur J Obstet Gynecol Reprod Biol. 2018 Nov;230:212-216. doi: 10.1016/j.ejogrb.2018.03.058. Epub 2018 Mar 28.
    • Review
    • An Estrogen-Related Dietary Pattern and Postmenopausal Breast Cancer Risk in a Cohort of Women with a Family History of Breast Cancer.
    • Guinter MA, Sandler DP, McLain AC, Merchant AT, Steck SE.
    • Cancer Epidemiol Biomarkers Prev. 2018 Oct;27(10):1223-1226. doi: 10.1158/1055-9965.EPI-18-0514. Epub 2018 Sep 19.
    • Hormone therapy and breast cancer risk after ovary removal in women with a BRCA1 mutation.
    • [No author given]
    • FORCE. XRAYS. 2018 Sep 7.

    Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers.

    • Genetic Variations, Exposure to Persistent Organic Pollutants and Breast Cancer Risk - A Greenlandic Case-Control Study.
    • Wielsøe M, Eiberg H, Ghisari M, Kern P, Lind O, Bonefeld-Jørgensen EC.
    • Basic Clin Pharmacol Toxicol. 2018 Sep;123(3):335-346. doi: 10.1111/bcpt.13002. Epub 2018 Apr 23.
    • Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    • Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2018 Sep;171(2):421-426. doi: 10.1007/s10549-018-4822-y. Epub 2018 May 17.
    • Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers.
    • Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • JAMA Oncol. 2018 Aug 1;4(8):1059-1065. doi: 10.1001/jamaoncol.2018.0211.

    Research News: Hormone therapy and breast cancer risk after ovary removal in women with a BRCA1 mutation. (FORCE, XRAYS)

    Commentary, Video: Menopausal Hormone Therapy and Risk for Breast Cancer in BRCA1 Mutation Carriers. (Medscape)

    • Smoking and FGFR2 rs2981582 variant independently modulate male breast cancer survival: A population-based study in Tuscany, Italy.
    • Zanna I, Silvestri V, Palli D, Magrini A, Rizzolo P, Saieva C, Zelli V, Bendinelli B, Vezzosi V, Valentini V, Bianchi S, Ottini L, Masala G.
    • Breast. 2018 Aug;40:85-91. doi: 10.1016/j.breast.2018.04.017. Epub 2018 Apr 28.
    • Ovarian stimulation for IVF and risk of primary breast cancer in BRCA1/2 mutation carriers.
    • Derks-Smeets IAP, Schrijver LH, de Die-Smulders CEM, Tjan-Heijnen VCG, van Golde RJT, Smits LJ, Caanen B, van Asperen CJ, Ausems M, Collée M, van Engelen K, Kets CM, van der Kolk L, Oosterwijk JC, van Os TAM; HEBON, Rookus MA, van Leeuwen FE, Gómez García EB.
    • Br J Cancer. 2018 May 1 [2018 Aug].;119(3):357-363. doi: 10.1038/s41416-018-0139-1.
    • Does stress increase risk of breast cancer? A 15-year prospective study.
    • Butow P, Price M, Coll J, Tucker K, Meiser B, Milne R, Wilson J, Heiniger L, Baylock B, Bullen T, Weideman P, Phillips KA; kConFab investigators; kConFab Clinical Follow-Up investigators; kConFab psychosocial investigators.
    • Psychooncology. 2018 Aug;27(8):1908-1914. doi: 10.1002/pon.4740. Epub 2018 May 4.
    • Effect of exercise on metabolic syndrome in black women by family history and predicted risk of breast cancer: The FIERCE Study.
    • Dash C, Taylor TR, Makambi KH, Hicks J, Hagberg JM, Adams-Campbell LL.
    • Cancer. 2018 Aug;124(16):3355-3363. doi: 10.1002/cncr.31569. Epub 2018 Jul 5.
    • Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study.
    • Schrijver LH, Olsson H, Phillips KA, Terry MB, Goldgar DE, Kast K, Engel C, Mooij TM, Adlard J, Barrowdale D, Davidson R, Eeles R, Ellis S, Evans DG, Frost D, Izatt L, Porteous ME, Side LE, Walker L, Berthet P, Bonadona V, Leroux D, Mouret-Fourme E, Venat-Bouvet L, Buys SS, Southey MC, John EM, Chung WK, Daly MB, Bane A, van Asperen CJ, Gómez Garcia EB, Mourits MJE, van Os TAM, Roos-Blom MJ, Friedlander ML, McLachlan SA, Singer CF, Tan YY, Foretova L, Navratilova M, Gerdes AM, Caldes T, Simard J, Olah E, Jakubowska A, Arver B, Osorio A, Noguès C, Andrieu N, Easton DF, van Leeuwen FE, Hopper JL, Milne RL, Antoniou AC, Rookus MA; EMBRACE, GENEPSO, BCFR, HEBON, kConFab, and IBCCS.
    • JNCI Cancer Spectr. 2018 Jun 28;2(2):pky023. doi: 10.1093/jncics/pky023. eCollection 2018 Apr.
    • The association between smoking and cancer incidence in BRCA1 and BRCA2 mutation carriers.
    • Ko KP, Kim SJ, Huzarski T, Gronwald J, Lubinski J, Lynch HT, Armel S, Park SK, Karlan B, Singer CF, Neuhausen SL, Narod SA, Kotsopoulos J; Hereditary Breast Cancer Clinical Study Group.
    • Int J Cancer. 2018 Jun 1;142(11):2263-2272. doi: 10.1002/ijc.31257. Epub 2018 Jan 25.
    • Reproductive history, breast-feeding and risk of triple negative breast cancer: The Breast Cancer Etiology in Minorities (BEM) study.
    • John EM, Hines LM, Phipps AI, Koo J, Longacre TA, Ingles SA, Baumgartner KB, Slattery ML, Wu AH.
    • Int J Cancer. 2018 Jun 1;142(11):2273-2285. doi: 10.1002/ijc.31258. Epub 2018 Jan 30.
    • Physical activity during adolescence and young adulthood and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
    • Lammert J, Lubinski J, Gronwald J, Huzarski T, Armel S, Eisen A, Meschino WS, Lynch HT, Snyder C, Eng C, Olopade OI, Ginsburg O, Foulkes WD, Elser C, Cohen SA, Kiechle M, Narod SA, Kotsopoulos J.
    • Breast Cancer Res Treat. 2018 Jun;169(3):561-571. doi: 10.1007/s10549-018-4694-1. Epub 2018 Feb 5.
    • Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    • Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2018 May 17. doi: 10.1007/s10549-018-4822-y. [Epub ahead of print]
    • Mammographic density changes in surgical weight loss-an indication for personalized screening.
    • Partain N, Mokdad A, Puzziferri N, Porembka J, Seiler S, Christie A, Farr D, Rivers A, Marilyn Leitch A, Wooldridge R, Huth J, Rao R.
    • BMC Med Imaging. 2018 May 9;18(1):10. doi: 10.1186/s12880-017-0242-4.
    • Complex Medical Decision-Making for a Trans-Feminine Youth with a BRCA1 Mutation.
    • Wolf-Gould CS, Riley MR, Carswell JM.
    • LGBT Health. 2018 May/Jun;5(4):221-225. doi: 10.1089/lgbt.2017.0149.
    • Case report
    • Modifiable Lifestyle Factors: Opportunities for (Hereditary) Breast Cancer Prevention - a Narrative Review.
    • Lammert J, Grill S, Kiechle M.
    • Breast Care (Basel). 2018 Apr;13(2):109-114. doi: 10.1159/000488995. Epub 2018 Apr 20.
    • Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers.
    • Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J; Hereditary Breast Cancer Clinical Study Group.
    • Int J Epidemiol. 2018 Mar 13. doi: 10.1093/ije/dyy039. [Epub ahead of print]
    • Commercially Available Lifestyle Modification Program Decreases Inflammatory Biomarkers in BRCA1/2+ Breast Cancer Survivors.
    • Sturgeon KM, Foo W, Schmitz KH/
    • Cancer Epidemiol Biomarkers Prev. 2018 Mar;27(3):357-357. doi: 10.1158/1055-9965.EPI-18-0063.
    • Conference abstract
    • A15 Blood cadmium (Cd) level as a marker of cancer risk in BRCA1 (+) prospective cohort study.
    • Marciniak W, Derkacz R, Baszuk P, Kuświk M, Kaczmarek K, Muszyńska M, Lener M, Huzarski T, Gronwald J, Oszurek O, Tołoczko-Grabarek A, Cybulski C, Dębniak T, Morawski A, Jakubowska A, Lubiński J.
    • Hered Cancer Clin Pract. 2018 Feb 28;16(Suppl 1):A15. Meeting abstracts from Clinical Genetics of Cancer 2017; Szczecin, Poland. 21-22 September 2017. doi: 10.1186/s13053-018-0087-z.
    • Conference abstract
    • A16 Arsenic as a marker of cancer risk.
    • Derkacz R, Marciniak W, Baszuk P, Kuświk M, Kaczmarek K, Muszyńska M, Lener M, Huzarski T, Gronwald J, Oszurek O, Tołoczko-Grabarek A, Cybulski C, Dębniak T, Morawski A, Jakubowska A, Lubiński J.
    • Hered Cancer Clin Pract. 2018 Feb 28;16(Suppl 1):A16. Meeting abstracts from Clinical Genetics of Cancer 2017; Szczecin, Poland. 21-22 September 2017. doi: 10.1186/s13053-018-0087-z.
    • Conference abstract
    • Difference in Risk of Breast and Ovarian Cancer According to Putative Functional Domain Regions in Korean BRCA1/2 Mutation Carriers.
    • Park JS, Lee ST, Han JW, Kim TI, Nam EJ, Park HS.
    • Clin Breast Cancer. 2018 Feb 20. pii: S1526-8209(17)30785-1. doi: 10.1016/j.clbc.2018.02.007. [Epub ahead of print]
    • Young age at first pregnancy does protect against early onset breast cancer in BRCA1 and BRCA2 mutation carriers.
    • Evans DG, Harkness EF, Howel S, Woodward ER, Howell A, Lalloo F.
    • Breast Cancer Res Treat. 2018 Feb;167(3):779-785. doi: 10.1007/s10549-017-4557-1. Epub 2017 Nov 7.
    • Combined Hormonal Contraceptive Use and Risk of Breast Cancer in a Population of Women With a Family History.
    • Grandi G, Toss A, Cagnacci A, Marcheselli L, Pavesi S, Facchinetti F, Cascinu S, Cortesi L.
    • Clin Breast Cancer. 2018 Feb;18(1):e15-e24. doi: 10.1016/j.clbc.2017.10.016. Epub 2017 Nov 14.
    • Women with hereditary breast cancer predispositions should avoid using their smartphones, tablets, and laptops at night.
    • Mortazavi SAR, Mortazavi SMJ.
    • Iran J Basic Med Sci. 2018 Feb;21(2):112-115. doi: 10.22038/IJBMS.2018.27711.6751.
    • Smoking and physical inactivity increase cancer prevalence in BRCA-1 and BRCA-2 mutation carriers: results from a retrospective observational analysis.
    • Grill S, Yahiaoui-Doktor M, Dukatz R, Lammert J, Ullrich M, Engel C, Pfeifer K, Basrai M, Siniatchkin M, Schmidt T, Weisser B, Rhiem K, Ditsch N, Schmutzler R, Bischoff SC, Halle M, Kiechle M.
    • Arch Gynecol Obstet. 2017 Dec;296(6):1135-1144. doi: 10.1007/s00404-017-4546-y. Epub 2017 Oct 3.
    • Health survey and assessment of the polymorphisms BRCA1/P871L, BRCA1/Q356R, and BRCA2/N372H in female gas station workers in Rio de Janeiro.
    • Silvestre RT, Delmonico L, Bravo M, Santiago F, Scherrer LR, Moreira ADS, Tabalipa M, Otero U, Ornellas MHF, Alves G.
    • Environ Mol Mutagen. 2017 Dec;58(9):730-734. doi: 10.1002/em.22120. Epub 2017 Sep 1.
    • Genetics of Breast and Gynecologic Cancers (PDQ®): Health Professional Version. Introduction. Risk Factors for Breast Cancer.
    • PDQ Cancer Genetics Editorial Board.
    • PDQ Cancer Information Summaries [Internet]. Bethesda, MD: National Cancer Institute. Updated 2017 Nov 30. Accessed 2017 Dec 8.
    • Reproductive factors as risk modifiers of breast cancer in BRCA mutation carriers and high-risk non-carriers.
    • Park B, Hopper JL, Win AK, Dowty JG, Sung HK, Ahn C, Kim SW, Lee MH, Lee J, Lee JW, Kang E, Yu JH, Kim KS, Moon BI, Han W, Noh DY, Park SK; KOHBRA Study Group.
    • Oncotarget. 2017 Oct 31;8(60):102110-102118. doi: 10.18632/oncotarget.22193. eCollection 2017 Nov 24.
    • The Effect of Reproductive Factors on Breast Cancer Presentation in Women Who Are BRCA Mutation Carrier.
    • Kim JY, Moon HG, Kang YJ, Han W, Noh WC, Jung Y, Moon BI, Kang E, Park SS, Lee MH, Park BY, Lee JW, Noh DY.
    • J Breast Cancer. 2017 Sep;20(3):279-285. doi: 10.4048/jbc.2017.20.3.279. Epub 2017 Sep 22.
    • Lifestyle Risk Factors for Breast Cancer in BRCA1/2-Mutation Carriers Around Childbearing Age.
    • van Erkelens A, Derks L, Sie AS, Egbers L, Woldringh G, Prins JB, Manders P, Hoogerbrugge N.
    • J Genet Couns. 2017 Aug;26(4):785-791. doi: 10.1007/s10897-016-0049-4. Epub 2016 Dec 13.
    • Rotating night work, lifestyle factors, obesity and promoter methylation in BRCA1 and BRCA2 genes among nurses and midwives.
    • Peplonska B, Bukowska A, Wieczorek E, Przybek M, Zienolddiny S, Reszka E.
    • PLoS One. 2017 Jun 8;12(6):e0178792. doi: 10.1371/journal.pone.0178792. eCollection 2017.
    • A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability.
    • Tan SLW, Chadha S, Liu Y, Gabasova E, Perera D, Ahmed K, Constantinou S, Renaudin X, Lee M, Aebersold R, Venkitaraman AR.
    • Cell. 2017 Jun 1;169(6):1105-1118.e15. doi: 10.1016/j.cell.2017.05.010.

    Preview, Research news:

    Aldehydes Pose a Threat to BRCA2 Mutation Carriers.

    Research news:

    Aldehydes Promote BRCA2 Haploinsufficiency and Genomic Instability.

    Research report, Commentary:

    Thwarting endogenous stress: BRCA protects against aldehyde toxicity.

    • Dependence of cancer risk from environmental exposures on underlying genetic susceptibility: an illustration with polycyclic aromatic hydrocarbons and breast cancer.
    • Shen J, Liao Y, Hopper JL, Goldberg M, Santella RM, Terry MB.
    • Br J Cancer. 2017 Apr 25;116(9):1229-1233. doi: 10.1038/bjc.2017.81. Epub 2017 Mar 28.
    • Reproductive factors and the risk of triple-negative breast cancer in white women and African-American women: a pooled analysis.
    • Ma H, Ursin G, Xu X, Lee E, Togawa K, Duan L, Lu Y, Malone KE, Marchbanks PA, McDonald JA, Simon MS, Folger SG, Sullivan-Halley J, Deapen DM, Press MF, Bernstein L.
    • Breast Cancer Res. 2017 Jan 13;19(1):6. doi: 10.1186/s13058-016-0799-9.
    • BRCA2: a grown-up cancer susceptibility gene.
    • Foulkes WD, Sugano K.
    • Endocr Relat Cancer. 2016 Oct;23(10):E1-E3.

    Review:

    BRCA2 functions: from DNA repair to replication fork stabilization.

    Review:

    Defects in homologous recombination repair behind the human diseases: FA and HBOC.

    Review:

    Synthetic lethality: the road to novel therapies for breast cancer.

    Review:

    Pancreatic ductal adenocarcinoma in BRCA2 mutation carriers.

    Review:

    Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers.

    • Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers.
    • Milne RL, Antoniou A.
    • Endocr Relat Cancer. 2016 Oct;23(10):T69-T84. Epub 2016 Aug 15.

    Introductory article, Editorial:

    BRCA2: a grown-up cancer susceptibility gene.

    • Effects of lifestyle intervention in BRCA1/2 mutation carriers on nutrition, BMI, and physical fitness (LIBRE study): study protocol for a randomized controlled trial.
    • Kiechle M, Engel C, Berling A, Hebestreit K, Bischoff SC, Dukatz R, Siniatchkin M, Pfeifer K, Grill S, Yahiaoui-Doktor M, Kirsch E, Niederberger U, Enders U, Löffler M, Meindl A, Rhiem K, Schmutzler R, Erickson N, Halle M.
    • Trials. 2016 Jul 29;17:368. doi: 10.1186/s13063-016-1504-0.
    • Recreational physical activity and risk of triple negative breast cancer in the California Teachers Study.
    • Ma H, Xu X, Clague J, Lu Y, Togawa K, Wang SS, Clarke CA, Lee E, Park HL, Sullivan-Halley J, Neuhausen SL, Bernstein L.
    • Breast Cancer Res. 2016 Jun 17;18(1):62. doi: 10.1186/s13058-016-0723-3.
    • Importance of hereditary and selected environmental risk factors in the etiology of inflammatory breast cancer: a case-comparison study.
    • Moslehi R, Freedman E, Zeinomar N, Veneroso C, Levine PH.
    • BMC Cancer. 2016 May 26;16(1):334. doi: 10.1186/s12885-016-2369-z.
    • Breast cancer in a male-to-female transsexual patient with a BRCA2 mutation.
    • Corman V, Potorac I, Manto F, Dassy S, Segers K, Thiry A, Bours V, Daly AF, Beckers A.
    • Endocr Relat Cancer. 2016 May;23(5):391-7. doi: 10.1530/ERC-16-0057. Epub 2016 Mar 21.
    • Case report

    Comments from NSGC Discussion Forum Cancer SIG

    Subject: Cancer risks for transgender patient

    • Effect of lifestyle and reproductive factors on the onset of breast cancer in female BRCA 1 and 2 mutation carriers.
    • Rieder V, Salama M, Glöckner L, Muhr D, Berger A, Tea MK, Pfeiler G, Rappaport-Fuerhauser C, Gschwantler-Kaulich D, Weingartshofer S, Singer CF.
    • Mol Genet Genomic Med. 2015 Dec 10;4(2):172-7. doi: 10.1002/mgg3.191. eCollection [2016 Mar;].
    • Uninterrupted Sedentary Behavior Downregulates BRCA1 Gene Expression.
    • Pettapiece-Phillips R, Kotlyar M, Chehade R, Salmena L, Narod SA, Akbari M, Jurisica I, Kotsopoulos J.
    • Cancer Prev Res (Phila). 2016 Jan;9(1):83-8. doi: 10.1158/1940-6207.CAPR-15-0291. Epub 2015 Nov 2.
    • BRCA1 and TP53 Gene-Mutations: Family Predisposition and Radioecological Risk of Developing Breast Cancer.
    • Apsalikov B, Manambaeva Z, Ospanov E, Massabayeva M, Zhabagin K, Zhagiparova Z, Maximov V, Voropaeva E, Apsalikov K, Belikhina T, Abdrahmanov R, Cherepkova E, Tanatarov S, Massadykov A, Urazalina N.
    • Asian Pac J Cancer Prev. 2016;17(8):4059-62.
    • Genetics: Relative risk.
    • Velasquez-Manoff M.
    • Nature. 2015 Nov 18;527(7578):S116-S117. doi: 10.1038/527S116a.
    • Review
    • Should women at high risk for cancer use oral contraceptive pills?
    • Moorman PG.
    • Per Med. 2015 Nov;12(6):533-535. doi: 10.2217/pme.15.36. Epub 2015 Nov 3.
    • Editorial
    • Epidemiological and clinicopathological characteristics of BRCA-positive and BRCA-negative breast cancer patients in Greece.
    • Triantafyllidou O, Vlachos IS, Apostolou P, Konstantopoulou I, Grivas A, Panopoulos C, Dimitrakakis C, Kassanos D, Loghis C, Bramis I, Vlahos N, Yannoukakos D, Fostira F.
    • J BUON. 2015 Jul-Aug;20(4):978-84.
    • Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
    • Cybulski C, Lubinski J, Huzarski T, Lynch HT, Randall SA, Neuhausen SL, Senter L, Friedman S, Ainsworth P, Singer C, Foulkes WD, Narod SA, Sun P, Kotsopoulos J.
    • Breast Cancer Res Treat. 2015 Jun;151(2):435-41. doi: 10.1007/s10549-015-3393-4. Epub 2015 May 3.
    • Breast Cancer Risk Associated with Estrogen Exposure and Truncating Mutation Location in BRCA1/2 Carriers.
    • Lecarpentier J, Noguès C, Mouret-Fourme E, Buecher B, Gauthier-Villars M, Stoppa-Lyonnet D, Bonadona V, Fricker JP, Berthet P, Caron O, Coupier I, Pujol P, Faivre L, Gesta P, Eisinger F, Mari V, Gladieff L, Lortholary A, Luporsi E, Leroux D, Venat-Bouvet L, Maugard CM, Colas C, Tinat J, Lasset C, Andrieu N; GENEPSO.
    • Cancer Epidemiol Biomarkers Prev. 2015 Apr;24(4):698-707. Epub 2015 Jan 22.
    • The role of body size and physical activity on the risk of breast cancer in BRCA mutation carriers.
    • Pettapiece-Phillips R, Narod SA, Kotsopoulos J.
    • Cancer Causes Control. 2015 Mar;26(3):333-44. doi: 10.1007/s10552-014-0521-0. Epub 2015 Jan 13.
    • Review
    • Tobacco and alcohol in relation to male breast cancer: an analysis of the male breast cancer pooling project consortium.
    • Cook MB, Guénel P, Gapstur SM, van den Brandt PA, Michels KB, Casagrande JT, Cooke R, Van Den Eeden SK, Ewertz M, Falk RT, Gaudet MM, Gkiokas G, Habel LA, Hsing AW, Johnson K, Kolonel LN, La Vecchia C, Lynge E, Lubin JH, McCormack VA, Negri E, Olsson H, Parisi D, Petridou ET, Riboli E, Sesso HD, Swerdlow A, Thomas DB, Willett WC, Brinton LA.
    • Cancer Epidemiol Biomarkers Prev. 2015 Mar;24(3):520-31. doi: 10.1158/1055-9965.EPI-14-1009. Epub 2014 Dec 16.
    • [Breast and ovarian cancer due to BRCA1&2 hereditary cancer predisposition syndrome and reproduction: Literature review.]
    • Jégu M, Der AS, Morcel K, Abadie C, Fritel X, Levêque J.
    • J Gynecol Obstet Biol Reprod (Paris). 2015 Jan;44(1):10-17. doi: 10.1016/j.jgyn.2014.10.011. Epub 2014 Nov 18.
    • Review, [Article in French]
    • Clinicopathologic characteristics of breast cancer in BRCA-carriers and non-carriers in women 35 years of age or less.
    • Bayraktar S, Amendola L, Gutierrez-Barrera AM, Hashmi SS, Amos C, Gambello M, Ready KJ, Arun B.
    • Breast. 2014 Dec;23(6):770-4. doi: 10.1016/j.breast.2014.08.010. Epub 2014 Sep 16.
    • Clinical Inquiry: do oral contraceptives put women with a family history of breast cancer at increased risk?
    • Freund R, Kelsberg G, Safranek S.
    • J Fam Pract. 2014 Sep;63(9):540, 549.
    • Clinical use of fertility agents and risk of breast cancer: a recent update for an old problem.
    • Tomao F, Lo Russo G, Spinelli GP, Tomao S.
    • Curr Opin Obstet Gynecol. 2014 Jun;26(3):130-7. doi: 10.1097/GCO.0000000000000067.
    • Review
    • Modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: systematic review and meta-analysis.
    • Friebel TM, Domchek SM, Rebbeck TR.
    • J Natl Cancer Inst. 2014 Jun;106(6):dju091. doi: 10.1093/jnci/dju091.

    Comments on NSGC Discussion Forum Cancer SIG

    Subject: chemoprevetion for ovarian cancer

    News: Study Identifies Modifiers of Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. (The ASCO Post)

    • Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers.
    • Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, Eisen A, Gilchrist D, Blum JL, Zakalik D, Pal T, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res Treat. 2014 Feb;143(3):579-86. doi: 10.1007/s10549-013-2823-4. Epub 2014 Jan 24.

    Comments on NSGC Discussion Forum Cancer SIG

    Subject: chemoprevetion for ovarian cancer

    Subject: Oral contraceptives and breast cancer

    Subject: BRCA1 Positive Patients and Oral Contraceptive Usage

    • Reproductive factors and breast cancer risk among BRCA1 or BRCA2 mutation carriers: results from ten studies.
    • Pan H, He Z, Ling L, Ding Q, Chen L, Zha X, Zhou W, Liu X, Wang S.
    • Cancer Epidemiol. 2014 Feb;38(1):1-8. doi: 10.1016/j.canep.2013.11.004. Epub 2013 Dec 12.

    Press: Reproductive Risk Factors for Breast Cancer Differ With BRCA1 vs BRCA2. (Medscape)

    • Dietary intake and breast cancer among carriers and noncarriers of BRCA mutations in the Korean Hereditary Breast Cancer Study.
    • Ko KP, Kim SW, Ma SH, Park B, Ahn Y, Lee JW, Lee MH, Kang E, Kim LS, Jung Y, Cho YU, Lee B, Lin JH, Park SK.
    • Am J Clin Nutr. 2013 Dec;98(6):1493-501. doi: 10.3945/ajcn.112.057760. Epub 2013 Oct 23.
    • Oral contraceptives and risk of ovarian cancer and breast cancer among high-risk women: a systematic review and meta-analysis.
    • Moorman PG, Havrilesky LJ, Gierisch JM, Coeytaux RR, Lowery WJ, Peragallo Urrutia R, Dinan M, McBroom AJ, Hasselblad V, Sanders GD, Myers ER.
    • J Clin Oncol. 2013 Nov 20;31(33):4188-98. doi: 10.1200/JCO.2013.48.9021. Epub 2013 Oct 21.
    • Risk factors for pregnancy-associated breast cancer: a report from the Nigerian Breast Cancer Study.
    • Hou N, Ogundiran T, Ojengbede O, Morhason-Bello I, Zheng Y, Fackenthal J, Adebamowo C, Anetor I, Akinleye S, Olopade OI, Huo D.
    • Ann Epidemiol. 2013 Sep;23(9):551-7. doi: 10.1016/j.annepidem.2013.06.008. Epub 2013 Jul 20.
    • Coffee and caffeine intake and breast cancer risk: An updated dose-response meta-analysis of 37 published studies.
    • Jiang W, Wu Y, Jiang X.
    • Gynecol Oncol. 2013 Jun;129(3):620-9. doi: 10.1016/j.ygyno.2013.03.014. Epub 2013 Mar 25.
    • Meta-Analysis, Review
    • Comparison of age at natural menopause in BRCA1/2 mutation carriers with a non-clinic-based sample of women in northern California.
    • Lin WT, Beattie M, Chen LM, Oktay K, Crawford SL, Gold EB, Cedars M, Rosen M.
    • Cancer. 2013 May 1;119(9):1652-9. doi: 10.1002/cncr.27952. Epub 2013 Jan 29.

    Press: Early Menopause May Occur in Women With BRCA Gene. (ScienceDaily)

    Press: Cancer gene mutation linked to earlier menopause. (Reuters/Living Beyond Breast Cancer)

    • Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant.
    • Obazee O, Justenhoven C, Winter S, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Hannelius U, Li J, Humphreys K, Hall P, Giles G, Severi G, Baglietto L, Southey M, Rabstein S, Harth V, Lotz A, Pesch B, Brüning T, Baisch C, Ko YD, Hamann U, Brauch H.
    • Breast Cancer Res Treat. 2013 Apr;138(2):543-8. doi: 10.1007/s10549-013-2448-7. Epub 2013 Feb 21.
    • Meta-Analysis
    • A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers.
    • Guinan EM, Hussey J, McGarrigle SA, Healy LA, O'Sullivan JN, Bennett K, Connolly EM.
    • BMC Cancer. 2013 Mar 21;13:138. doi: 10.1186/1471-2407-13-138.
    • Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study.
    • Andersen SW, Trentham-Dietz A, Figueroa JD, Titus LJ, Cai Q, Long J, Hampton JM, Egan KM, Newcomb PA.
    • Menopause. 2013 Mar;20(3):354-8. doi: 10.1097/GME.0b013e318268ca46.
    • Evidence of Gene-Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors.
    • Nickels S, Truong T, Hein R, Stevens K, Buck K, Behrens S, Eilber U, Schmidt M, Häberle L, Vrieling A, Gaudet M, Figueroa J, Schoof N, Spurdle AB, Rudolph A, Fasching PA, Hopper JL, Makalic E, Schmidt DF, Southey MC, Beckmann MW, Ekici AB, Fletcher O, Gibson L, Dos Santos Silva I, Peto J, Humphreys MK, Wang J, Cordina-Duverger E, Menegaux F, Nordestgaard BG, Bojesen SE, Lanng C, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Müller H, Arndt V, Stegmaier C, Brauch H, Brüning T, Harth V, The Genica Network, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Kconfab, Group AM, Lambrechts D, Smeets D, Neven P, Paridaens R, Flesch-Janys D, Obi N, Wang-Gohrke S, Couch FJ, Olson JE, Vachon CM, Giles GG, Severi G, Baglietto L, Offit K, John EM, Miron A, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Chanock SJ, Lissowska J, Liu J, Cox A, Cramp H, Connley D, Balasubramanian S, Dunning AM, Shah M, Trentham-Dietz A, Newcomb P, Titus L, Egan K, Cahoon EK, Rajaraman P, Sigurdson AJ, Doody MM, Guénel P, Pharoah PD, Schmidt MK, Hall P, Easton DF, Garcia-Closas M, Milne RL, Chang-Claude J.
    • PLoS Genet. 2013 Mar;9(3):e1003284. doi: 10.1371/journal.pgen.1003284. Epub 2013 Mar 27.
    • Analysis of polymorphisms in the circadian-related genes and breast cancer risk in Norwegian nurses working night shifts.
    • Zienolddiny S, Haugen A, Lie JA, Kjuus H, Anmarkrud KH, Kjærheim K.
    • Breast Cancer Res. 2013;15(4):R53.
    • Multifocal Breast Cancer in Young Women with Prolonged Contact between Their Breasts and Their Cellular Phones.
    • West JG, Kapoor NS, Liao SY, Chen JW, Bailey L, Nagourney RA.
    • Case Rep Med. 2013;2013:354682. doi: 10.1155/2013/354682. Epub 2013 Sep 18.
    • High coffee intake, but not caffeine, is associated with reduced estrogen receptor negative and postmenopausal breast cancer risk with no effect modification by CYP1A2 genotype.
    • Lowcock EC, Cotterchio M, Anderson LN, Boucher BA, El-Sohemy A.
    • Nutr Cancer. 2013;65(3):398-409. doi: 10.1080/01635581.2013.768348.
    • Circadian genes and breast cancer susceptibility in rotating shift workers.
    • Monsees GM, Kraft P, Hankinson SE, Hunter DJ, Schernhammer ES.
    • Int J Cancer. 2012 Dec 1;131(11):2547-52. doi: 10.1002/ijc.27564. Epub 2012 Sep 7.
    • Breast cancer risk factors differ between Asian and white women with BRCA1/2 mutations.
    • de Bruin MA, Kwong A, Goldstein BA, Lipson JA, Ikeda DM, McPherson L, Sharma B, Kardashian A, Schackmann E, Kingham KE, Mills MA, West DW, Ford JM, Kurian AW.
    • Fam Cancer. 2012 Sep;11(3):429-39. doi: 10.1007/s10689-012-9531-9.
    • Variation in breast cancer risk associated with factors related to pregnancies according to truncating mutation location, in the French National BRCA1 and BRCA2 mutations carrier cohort (GENEPSO).
    • Lecarpentier J, Noguès C, Mouret-Fourme E, Gauthier-Villars M, Lasset C, Fricker JP, Caron O, Stoppa-Lyonnet D, Berthet P, Faivre L, Bonadona V, Buecher B, Coupier I, Gladieff L, Gesta P, Eisinger F, Frénay M, Luporsi E, Lortholary A, Colas C, Dugast C, Longy M, Pujol P, Tinat J; GENEPSO, Lidereau R, Andrieu N.
    • Breast Cancer Res. 2012 Jul 3;14(4):R99. doi: 10.1186/bcr3218.
    • Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study.
    • Kotsopoulos J, Sukiennicki G, Muszyńska M, Gackowski D, Kąklewski K, Durda K, Jaworska K, Huzarski T, Gronwald J, Byrski T, Ashuryk O, Dębniak T, Tołoczko-Grabarek A, Stawicka M, Godlewski D, Oliński R, Jakubowska A, Narod SA, Lubinski J.
    • Cancer Causes Control. 2012 Jul;23(7):1065-74. doi: 10.1007/s10552-012-9975-0. Epub 2012 May 11.
    • Young women with family history of breast cancer and their risk factors for benign breast disease.
    • Berkey CS, Tamimi RM, Rosner B, Frazier AL, Colditz GA.
    • Cancer. 2012 Jun 1;118(11):2796-803. doi: 10.1002/cncr.26519. Epub 2011 Nov 14.

    Press: Family History, Alcohol Affect Risk for Benign Breast Disease (Medscape)

    • Alcohol, genetics and risk of breast cancer in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
    • McCarty CA, Reding DJ, Commins J, Williams C, Yeager M, Burmester JK, Schairer C, Ziegler RG.
    • Breast Cancer Res Treat. 2012 Jun;133(2):785-92. doi: 10.1007/s10549-012-1972-1. Epub 2012 Feb 14.
    • Vitamin D intake, vitamin D receptor polymorphisms, and breast cancer risk among women living in the southwestern U.S.
    • Rollison DE, Cole AL, Tung KH, Slattery ML, Baumgartner KB, Byers T, Wolff RK, Giuliano AR.
    • Breast Cancer Res Treat. 2012 Apr;132(2):683-91. doi: 10.1007/s10549-011-1885-4. Epub 2011 Dec 1.
    • Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
    • Kotsopoulos J, Lubinski J, Salmena L, Lynch HT, Kim-Sing C, Foulkes WD, Ghadirian P, Neuhausen SL, Demsky R, Tung N, Ainsworth P, Senter L, Eisen A, Eng C, Singer C, Ginsburg O, Blum J, Huzarski T, Poll A, Sun P, Narod SA; the Hereditary Breast Cancer Clinical Study Group.
    • Breast Cancer Res. 2012 Mar 9;14(2):R42.