General ~ Contralateral Prophylactic Mastectomy
~ Genetics of Breast & Ovarian Cancer

List was last updated on Sep 21, 2020 @ 8:30 am.


    • Robot-assisted Nipple-sparing Mastectomy with Immediate Breast Reconstruction: An Initial Experience of the Korea Robot-Endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG).
    • Ryu JM, Kim JY, Choi HJ, Ko BS, Kim J, Cho J, Lee MH, Choi JE, Kim JH, Lee J, Jung SM, Shin HJ, Lee J, Park HS.
    • Ann Surg. 2020 Sep 15. doi: 10.1097/SLA.0000000000004492. Epub ahead of print.
    • A Retrospective Analysis of the Relationship Between the Result of BRCA1/2 Genetic Testing and Surgical Method Selection in Japan.
    • Inuzuka M, Watanabe C, Yokoyama S, Kuwayama T, Akashi-Tanaka S, Arai M, Nakamura S; Registration Committee of the Japanese HBOC consortium.
    • Clin Breast Cancer. 2020 Aug 20:S1526-8209(20)30209-3. doi: 10.1016/j.clbc.2020.08.004. Epub ahead of print.
    • Contralateral Risk-Reducing Mastectomy in Breast Cancer Patients Who Undergo Multigene Panel Testing.
    • Murphy BL, Yi M, Arun BK, Gutierrez Barrera AM, Bedrosian I.
    • Ann Surg Oncol. 2020 Jul 27. doi: 10.1245/s10434-020-08889-6. Epub ahead of print.
    • Contralateral breast cancer and tumor recurrence in BRCA1/2 carriers and non-carriers at a high risk of hereditary breast cancer after bilateral mastectomy.
    • Allué Cabañuz M, Domingo Bretón M, Chóliz Ezquerro J, Arribas Del Amo MD, Güemes Sánchez AT.
    • Cir Esp. 2020 Jun 3:S0009-739X(20)30115-9. English, Spanish. doi: 10.1016/j.ciresp.2020.04.008. Epub ahead of print.
    • [Article in English, Spanish.]
    • ASTRO Radiation Therapy Summary of the ASCO-ASTRO-SSO Guideline on Management of Hereditary Breast Cancer.
    • Trombetta MG, Dragun A, Mayr NA, Pierce LJ.
    • Pract Radiat Oncol. 2020 May 21:S1879-8500(20)30099-0. doi: 10.1016/j.prro.2020.04.003. Epub ahead of print.

    Guideline:

    Management of Hereditary Breast Cancer: American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Guideline.

    • Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts.
    • Giardiello D, Hauptmann M, Steyerberg EW, Adank MA, Akdeniz D, Blom JC, Blomqvist C, Bojesen SE, Bolla MK, Brinkhuis M, Chang-Claude J, Czene K, Devilee P, Dunning AM, Easton DF, Eccles DM, Fasching PA, Figueroa J, Flyger H, García-Closas M, Haeberle L, Haiman CA, Hall P, Hamann U, Hopper JL, Jager A, Jakubowska A, Jung A, Keeman R, Koppert LB, Kramer I, Lambrechts D, Le Marchand L, Lindblom A, Lubinski J, Manoochehri M, Mariani L, Nevanlinna H, Oldenburg HSA, Pelders S, Pharoah PDP, Shah M, Siesling S, Smit VTHBM, Southey MC, Tapper WJ, Tollenaar RAEM, van den Broek AJ, van Deurzen CHM, van Leeuwen FE, van Ongeval C, Van't Veer LJ, Wang Q, Wendt C, Westenend PJ, Hooning MJ, Schmidt MK.
    • Breast Cancer Res Treat. 2020 Apr 11. doi: 10.1007/s10549-020-05611-8. [Epub ahead of print]
    • Management of Hereditary Breast Cancer: American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Guideline.
    • Tung NM, Boughey JC, Pierce LJ, Robson ME, Bedrosian I, Dietz JR, Dragun A, Gelpi JB, Hofstatter EW, Isaacs CJ, Jatoi I, Kennedy E, Litton JK, Mayr NA, Qamar RD, Trombetta MG, Harvey BE, Somerfield MR, Zakalik D.
    • J Clin Oncol. 2020 Apr 3:JCO2000299. doi: 10.1200/JCO.20.00299. [Epub ahead of print]

    Summary, Review:

    Management of Hereditary Breast Cancer: ASCO, ASTRO, and SSO Guideline.

    Summary, Review:

    ASTRO Radiation Therapy Summary of the ASCO-ASTRO-SSO Guideline on Management of Hereditary Breast Cancer.

    • Differences in physician opinions about controversial issues surrounding contralateral prophylactic mastectomy (CPM): A survey of physicians from accredited breast centers in the United States.
    • Yao K, Bleicher R, Moran M, Chang C, Dietz J, Stearns V, Connolly J, Sarantou T, Kurtzman S; National Accreditation Program for Breast Centers Data Working Group.
    • Cancer Med. 2020 Mar 11. doi: 10.1002/cam4.2914. [Epub ahead of print]
    • Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer Who Are Genetic Carriers, Have a Strong Family History or Are just Young at Presentation.
    • Teoh V, Tasoulis MK, Gui G.
    • Cancers (Basel). 2020 Jan 6;12(1). pii: E140. doi: 10.3390/cancers12010140.
    • Predictors of contralateral prophylactic mastectomy in genetically high risk newly diagnosed breast cancer patients.
    • Tynan M, Peshkin BN, Isaacs C, Willey S, Valdimarsdottir HB, Nusbaum R, Hooker G, O'Neill SC, Jandorf L, Kelly SP, Heinzmann J, Kelleher S, Poggi E, Schwartz MD.
    • Breast Cancer Res Treat. 2020 Jan 1. doi: 10.1007/s10549-019-05515-2. [Epub ahead of print]
    • Trends in Contralateral Prophylactic Mastectomy.
    • Fairbairn K, Cervantes A, Rayhrer C, Steen S.
    • Aesthetic Plast Surg. 2019 Dec 18. doi: 10.1007/s00266-019-01582-4. [Epub ahead of print]
    • Prediction and clinical utility of a contralateral breast cancer risk model.
    • Giardiello D, Steyerberg EW, Hauptmann M, Adank MA, Akdeniz D, Blomqvist C, Bojesen SE, Bolla MK, Brinkhuis M, Chang-Claude J, Czene K, Devilee P, Dunning AM, Easton DF, Eccles DM, Fasching PA, Figueroa J, Flyger H, García-Closas M, Haeberle L, Haiman CA, Hall P, Hamann U, Hopper JL, Jager A, Jakubowska A, Jung A, Keeman R, Kramer I, Lambrechts D, Le Marchand L, Lindblom A, Lubiński J, Manoochehri M, Mariani L, Nevanlinna H, Oldenburg HSA, Pelders S, Pharoah PDP, Shah M, Siesling S, Smit VTHBM, Southey MC, Tapper WJ, Tollenaar RAEM, van den Broek AJ, van Deurzen CHM, van Leeuwen FE, van Ongeval C, Van't Veer LJ, Wang Q, Wendt C, Westenend PJ, Hooning MJ, Schmidt MK.
    • Breast Cancer Res. 2019 Dec 17;21(1):144. doi: 10.1186/s13058-019-1221-1.
    • Is prophylactic mastectomy justified in women without BRCA mutation?
    • Rutgers EJT.
    • Breast. 2019 Nov;48 Suppl 1:S62-S64. doi: 10.1016/S0960-9776(19)31126-9.
    • Assessing the additional surgical risk of contralateral prophylactic mastectomy and immediate breast implant reconstruction.
    • Nealon KP, Sobti N, Gadd M, Specht M, Liao EC.
    • Breast Cancer Res Treat. 2019 Oct 11. doi: 10.1007/s10549-019-05460-0. [Epub ahead of print]
    • Trends in contralateral prophylactic mastectomy rate according to clinicopathologic and socioeconomic status.
    • Jeon HJ, Park HS, Park JS, Nam EJ, Lee ST, Han J.
    • Ann Surg Treat Res. 2019 Sep;97(3):113-118. doi: 10.4174/astr.2019.97.3.113. Epub 2019 Aug 29.
    • Hereditary breast cancer: screening and risk reducing surgery.
    • Renzulli M, Zanotti S, Clemente A, Mineo G, Tovoli F, Reginelli A, Barile A, Cappabianca S, Taffurelli M, Golfieri R.
    • Gland Surg. 2019 Sep;8(Suppl 3):S142-S149. doi: 10.21037/gs.2019.04.04.
    • Impact of genetic counseling on the uptake of contralateral prophylactic mastectomy among younger women with breast cancer.
    • Terkelsen T, Rønning H, Skytte AB.
    • Acta Oncol. 2019 Aug 5:1-6. doi: 10.1080/0284186X.2019.1648860. [Epub ahead of print]
    • Contralateral prophylactic mastectomy: What should not be forgotten to improve communication between clinicians and patients!
    • Franceschini G, Di Leone A, Masetti R.
    • Patient Educ Couns. 2019 Aug;102(8):1573-1574. doi: 10.1016/j.pec.2019.03.006. Epub 2019 Mar 15.
    • Letter
    • Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer.
    • Bercow AS, Eisenhauer EL.
    • J Surg Oncol. 2019 Jul 29. doi: 10.1002/jso.25645. [Epub ahead of print]
    • Review
    • Residual glandular tissue (RGT) in BRCA1/2 germline mutation carriers with unilateral and bilateral prophylactic mastectomies.
    • Grinstein O, Krug B, Hellmic M, Siedek F, Malter W, Burke C, Schmutzler R, Maintz D, Rhiem K.
    • Surg Oncol. 2019 Jun;29:126-133. doi: 10.1016/j.suronc.2019.04.009. Epub 2019 May 3.
    • Body image problems in women with and without breast cancer 6-20 years after bilateral risk-reducing surgery - A prospective follow-up study.
    • Bai L, Arver B, Johansson H, Sandelin K, Wickman M, Brandberg Y.
    • Breast. 2019 Apr;44:120-127. doi: 10.1016/j.breast.2019.01.013. Epub 2019 Feb 1.
    • Prophylactic irradiation to the contralateral breast for BRCA mutation carriers with early-stage breast cancer.
    • Evron E, Ben-David AM, Goldberg H, Fried G, Kaufman B, Catane R, Pfeffer MR, Geffen DB, Chernobelsky P, Karni T, Abdah-Bortnyak R, Rosengarten O, Matceyevsky D, Inbar M, Kuten A, Corn BW.
    • Ann Oncol. 2019 Mar 1;30(3):412-417. doi: 10.1093/annonc/mdy515.

    Editorial:

    Is bilateral radiation an option for BRCA mutation carriers with unilateral breast cancer?

    • Reframing the conversation about contralateral prophylactic mastectomy: Preparing women for postsurgical realities.
    • Bloom DL, Chapman BM, Wheeler SB, McGuire KP, Lee CN, Weinfurt K, Rosenstein DL, Plichta JK, Jacobson Vann JC, Hwang ES.
    • Psychooncology. 2019 Feb;28(2):394-400. doi: 10.1002/pon.4955. Epub 2018 Dec 28.
    • Helping Patients Manage the Anxiety Behind Contralateral Prophylactic Mastectomy.
    • Schapira L, Parker P.
    • Medscape. Medscape Oncology. 2019 Jan 17.

    Original research:

    Prospective Study of Psychosocial Outcomes of Having Contralateral Prophylactic Mastectomy Among Women With Nonhereditary Breast Cancer.

    • Feasibility study of contralateral risk-reducing mastectomy with breast reconstruction for breast cancer patients with BRCA mutations in Japan.
    • Yoshimura A, Okumura S, Sawaki M, Hattori M, Ishiguro J, Adachi Y, Kotani H, Gondo N, Kataoka A, Iwase M, Onishi S, Sugino K, Terada M, Horisawa N, Mori M, Takaiso N, Hyodo I, Iwata H.
    • Breast Cancer. 2018 Sep;25(5):539-546. doi: 10.1007/s12282-018-0850-z. Epub 2018 Mar 8.
    • Evolving surgical treatment decisions for male breast cancer: an analysis of the National Surgical Quality Improvement Program (NSQIP) database.
    • Elmi M, Sequeira S, Azin A, Elnahas A, McCready DR, Cil TD.
    • Breast Cancer Res Treat. 2018 Sep;171(2):427-434. doi: 10.1007/s10549-018-4830-y. Epub 2018 May 28.
    • Surgery for BRCA, TP53 and PALB2: a literature review.
    • Song CV, Teo SH, Taib NA, Yip CH.
    • Ecancermedicalscience. 2018 Aug 29;12:863. doi: 10.3332/ecancer.2018.863. eCollection 2018.
    • Prophylactic mastectomy for the prevention of breast cancer: Review of the literature.
    • Alaofi RK, Nassif MO, Al-Hajeili MR.
    • Avicenna J Med. 2018 Jul-Sep;8(3):67-77. doi: 10.4103/ajm.AJM_21_18.
    • Risk-reducing mastectomy for the prevention of primary breast cancer.
    • Carbine NE, Lostumbo L, Wallace J, Ko H.
    • Cochrane Database Syst Rev. 2018 Apr 5;4:CD002748. doi: 10.1002/14651858.CD002748.pub4.
    • Review, Meta-Analysis

    Summary: Women should be aware of their true risk of developing breast cancer and the limitations of current evidence when considering risk-reducing mastectomy. (Cochrane Library)

    • Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.
    • Müller D, Danner M, Rhiem K, Stollenwerk B, Engel C, Rasche L, Borsi L, Schmutzler R, Stock S.
    • Eur J Health Econ. 2018 Apr;19(3):341-353. doi: 10.1007/s10198-017-0887-5. Epub 2017 Apr 5.
    • Oncologic Safety of Prophylactic Nipple-Sparing Mastectomy in a Population With BRCA Mutations: A Multi-institutional Study.
    • Jakub JW, Peled AW, Gray RJ, Greenup RA, Kiluk JV, Sacchini V, McLaughlin SA, Tchou JC, Vierkant RA, Degnim AC, Willey S.
    • JAMA Surg. 2018 Feb 1;153(2):123-129. doi: 10.1001/jamasurg.2017.3422.

    Commentary:

    When is a Little Breast Tissue Too Much?: Nipple-Sparing Risk-Reducing Mastectomy in BRCA Carriers.

    • The Use of Sentinel Lymph Node Biopsy in BRCA1/2 Mutation Carriers Undergoing Prophylactic Mastectomy: A Retrospective Consecutive Case-Series Study.
    • Câmara S, Pereira D, André S, Mira B, Vaz F, Oom R, Marques JC, Leal de Faria J, Rodrigues Dos Santos C.
    • Int J Breast Cancer. 2018 Jan 1;2018:1426369. doi: 10.1155/2018/1426369. eCollection 2018.
    • Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG.
    • Soenderstrup IMH, Laenkholm AV, Jensen MB, Eriksen JO, Gerdes AM, Hansen TVO, Kruse TA, Larsen MJ, Pedersen IS, Rossing M, Thomassen M, Ejlertsen B.
    • Acta Oncol. 2018 Jan;57(1):95-101. doi: 10.1080/0284186X.2017.1398415. Epub 2017 Nov 22.
    • The psycho-social impact of contralateral risk reducing mastectomy (CRRM) on women: a rapid review.
    • Collins K, Gee M, Clack A, Wyld L.
    • Psychooncology. 2018 Jan;27(1):43-52. doi: 10.1002/pon.4448. Epub 2017 May 31.
    • Review
    • Prophylactic Surgery: For Whom, When and How?
    • Mau C, Untch M.
    • Breast Care (Basel). 2017 Dec;12(6):379-384. doi: 10.1159/000485830. Epub 2017 Dec 13.
    • Non-BRCA1/2 Breast Cancer Susceptibility Genes: A New Frontier with Clinical Consequences for Plastic Surgeons.
    • Frey JD, Salibian AA, Schnabel FR, Choi M, Karp NS.
    • Plast Reconstr Surg Glob Open. 2017 Nov 20;5(11):e1564. doi: 10.1097/GOX.0000000000001564. eCollection 2017 Nov.
    • Determining the Oncologic Safety of Autologous Fat Grafting as a Reconstructive Modality: An Institutional Review of Breast Cancer Recurrence Rates and Surgical Outcomes.
    • Cohen O, Lam G, Karp N, Choi M.
    • Plast Reconstr Surg. 2017 Sep;140(3):382e-392e. doi: 10.1097/PRS.0000000000003576.
    • Contralateral Prophylactic Mastectomy (CPM) Consensus Statement from the American Society of Breast Surgeons: Data on CPM Outcomes and Risks.
    • Boughey JC, Attai DJ, Chen SL, Cody HS, Dietz JR, Feldman SM, Greenberg CC, Kass RB, Landercasper J, Lemaine V, MacNeill F, Song DH, Staley AC, Wilke LG, Willey SC, Yao KA, Margenthaler JA.
    • Ann Surg Oncol. 2016 Oct;23(10):3100-5. doi: 10.1245/s10434-016-5443-5. Epub 2016 Jul 28.

    Clinical Guideline

    Contralateral Prophylactic Mastectomy Consensus Statement from the American Society of Breast Surgeons: Additional Considerations and a Framework for Shared Decision Making.

    News: Contralateral Prophylactic Mastectomy Discouraged: ASBrS (Medscape Oncology)

    • Contralateral prophylactic mastectomy: current perspectives.
    • Yao K, Sisco M, Bedrosian I.
    • Int J Womens Health. 2016 Jun 22;8:213-23. doi: 10.2147/IJWH.S82816. eCollection 2016.
    • The value of breast MRI in high-risk patients with newly diagnosed breast cancer to exclude invasive disease in the contralateral prophylactic mastectomy: Is there a role to choose wisely patients for sentinel node biopsy?
    • Freitas V, Crystal P, Kulkarni SR, Ghai S, Bukhanov K, Escallon J, Scaranelo AM.
    • Cancer Med. 2016 Jun;5(6):1031-6. doi: 10.1002/cam4.663. Epub 2016 Mar 18.
    • What is new in the surgical management and prevention of breast cancer?
    • Spillane AJ.
    • Med J Aust. 2016 May 2;204(8):311-4.
    • Survey of the Deficits in Surgeons' Knowledge of Contralateral Prophylactic Mastectomy.
    • Yao K, Belkora J, Sisco M, Rosenberg S, Bedrosian I, Liederbach E, Wang C.
    • JAMA Surg. 2016 Apr 1;151(4):391-3. doi: 10.1001/jamasurg.2015.3601.
    • Letter
    • Attitudes to contralateral risk reducing mastectomy among breast and plastic surgeons in England.
    • Basu NN, Littlechild S, Barr L, Ross GL, Evans DG.
    • Ann R Coll Surg Engl. 2016 Feb;98(2):121-7. doi: 10.1308/rcsann.2016.0039. Epub 2016 Jan 7.
    • Surgical Decision Making in the BRCA-Positive Population: Institutional Experience and Comparison with Recent Literature.
    • Flippo-Morton T, Walsh K, Chambers K, Amacker-North L, White B, Sarantou T, Boselli DM, White RL Jr.
    • Breast J. 2016 Jan-Feb;22(1):35-44. doi: 10.1111/tbj.12521. Epub 2015 Dec 23.
    • Breast Reconstruction Options.
    • Kathy Steligo.
    • FORCE. Be Empowered Webinars. 2015 Oct 19.
    • Personalization of loco-regional care for primary breast cancer patients (part 2).
    • Toi M, Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson JF, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow LW, Huang CS, Han W, Noguchi S, Pegram MD, Yamauchi H, Lee ES, Larionov AA, Bevilacqua JL, Yoshimura M, Sugie T, Yamauchi A, Krop IE, Noh DY, Klimberg VS; 2014 Kyoto Breast Cancer Consensus Conference.
    • Future Oncol. 2015 May;11(9):1301-5. doi: 10.2217/fon.15.66.
    • Prophylactic Mastectomy Offers Minimal Gain in Breast Cancer.
    • Miriam E. Tucker.
    • Medscape Medical News. Conference News. American College of Surgeons (ACS) 2013 Annual Clinical Congress. 2013 Oct 8.
    • Contralateral prophylactic mastectomy in women with breast cancer: trends, predictors, and areas for future research.
    • Tracy MS, Rosenberg SM, Dominici L, Partridge AH.
    • Breast Cancer Res Treat. 2013 Aug;140(3):447-52. doi: 10.1007/s10549-013-2643-6. Epub 2013 Jul 28.
    • Breast surgeons' perceptions and attitudes towards contralateral prophylactic mastectomy.
    • Musiello T, Bornhammar E, Saunders C.
    • ANZ J Surg. 2013 Jul;83(7-8):527-32. doi: 10.1111/j.1445-2197.2012.06209.x. Epub 2012 Oct 8.
    • [Methods of surgical prevention of breast cancer and of ovarian cancer in BRCA mutation carriers].
    • Bit-Sava EM, Belogurova MB, Imianitov EN, Balandov SG, Korniushin OV, Borisov MK.
    • Vopr Onkol. 2013;59(2):5-11.
    • Review, [Article in Russian]
    • Association between contralateral prophylactic mastectomy and breast cancer outcomes by hormone receptor status.
    • Brewster AM, Bedrosian I, Parker PA, Dong W, Peterson SK, Cantor SB, Crosby M, Shen Y.
    • Cancer. 2012 Nov 15;118(22):5637-43. doi: 10.1002/cncr.27574. Epub 2012 Apr 19.
    • Role of Breast Surgery in BRCA Mutation Carriers.
    • Nestle-Krämling C, Kühn T.
    • Breast Care (Basel). 2012 Oct;7(5):378-82. doi: 10.1159/000343717.