Cancer following ~ Contralateral Prophylactic Mastectomy
~ Genetics of Breast & Ovarian Cancer

List was last updated on Jun 8, 2020 @ 12:20 pm.

    • Contralateral breast cancer and tumor recurrence in BRCA1/2 carriers and non-carriers at a high risk of hereditary breast cancer after bilateral mastectomy.
    • Allué Cabañuz M, Domingo Bretón M, Chóliz Ezquerro J, Arribas Del Amo MD, Güemes Sánchez AT.
    • Cir Esp. 2020 Jun 3:S0009-739X(20)30115-9. English, Spanish. doi: 10.1016/j.ciresp.2020.04.008. Epub ahead of print.
    • [Article in English, Spanish.]
    • Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer Who Are Genetic Carriers, Have a Strong Family History or Are just Young at Presentation.
    • Teoh V, Tasoulis MK, Gui G.
    • Cancers (Basel). 2020 Jan 6;12(1). pii: E140. doi: 10.3390/cancers12010140.
    • Residual glandular tissue (RGT) in BRCA1/2 germline mutation carriers with unilateral and bilateral prophylactic mastectomies.
    • Grinstein O, Krug B, Hellmic M, Siedek F, Malter W, Burke C, Schmutzler R, Maintz D, Rhiem K.
    • Surg Oncol. 2019 Jun;29:126-133. doi: 10.1016/j.suronc.2019.04.009. Epub 2019 May 3.
    • Surgery for BRCA, TP53 and PALB2: a literature review.
    • Song CV, Teo SH, Taib NA, Yip CH.
    • Ecancermedicalscience. 2018 Aug 29;12:863. doi: 10.3332/ecancer.2018.863. eCollection 2018.
    • Risk-reducing mastectomy for the prevention of primary breast cancer.
    • Carbine NE, Lostumbo L, Wallace J, Ko H.
    • Cochrane Database Syst Rev. 2018 Apr 5;4:CD002748. doi: 10.1002/14651858.CD002748.pub4.
    • Review, Meta-Analysis

    Summary: Women should be aware of their true risk of developing breast cancer and the limitations of current evidence when considering risk-reducing mastectomy. (Cochrane Library)

    • Oncologic Safety of Prophylactic Nipple-Sparing Mastectomy in a Population With BRCA Mutations: A Multi-institutional Study.
    • Jakub JW, Peled AW, Gray RJ, Greenup RA, Kiluk JV, Sacchini V, McLaughlin SA, Tchou JC, Vierkant RA, Degnim AC, Willey S.
    • JAMA Surg. 2018 Feb 1;153(2):123-129. doi: 10.1001/jamasurg.2017.3422.


    When is a Little Breast Tissue Too Much?: Nipple-Sparing Risk-Reducing Mastectomy in BRCA Carriers.

    • Outcomes of contralateral prophylactic mastectomy in relation to familial history: a decision analysis (BRCR-D-16-00033).
    • Davies KR, Brewster AM, Bedrosian I, Parker PA, Crosby MA, Peterson SK, Shen Y, Volk RJ, Cantor SB.
    • Breast Cancer Res. 2016 Sep 20;18(1):93. doi: 10.1186/s13058-016-0752-y.
    • Effectiveness of Prophylactic Surgeries in BRCA1 or BRCA2 Mutation Carriers: A Meta-analysis and Systematic Review.
    • Li X, You R, Wang X, Liu C, Xu Z, Zhou J, Yu B, Xu T, Cai H, Zou Q.
    • Clin Cancer Res. 2016 Aug 1;22(15):3971-81. doi: 10.1158/1078-0432.CCR-15-1465. Epub 2016 Mar 15.
    • Contralateral prophylactic mastectomy: current perspectives.
    • Yao K, Sisco M, Bedrosian I.
    • Int J Womens Health. 2016 Jun 22;8:213-23. doi: 10.2147/IJWH.S82816. eCollection 2016.
    • More Proof: Nipple-Sparing Mastectomy Safe for BRCA Carriers.
    • Nick Mulcahy.
    • Medscape Medical News. Conference News. 17th Annual Meeting of the American Society of Breast Surgeons. 2016 Apr 21.
    • Improved overall survival after contralateral risk-reducing mastectomy in BRCA1/2 mutation carriers with a history of unilateral breast cancer: A prospective analysis.
    • A M Heemskerk-Gerritsen B, Rookus MA, Aalfs CM, Ausems MG, Collée JM, Jansen L, Kets CM, Keymeulen KB, Koppert LB, Meijers-Heijboer HE, Mooij TM, Tollenaar RA, Vasen HF, Hebon, Hooning MJ, Seynaeve C.
    • Int J Cancer. 2015 Feb 15;136(3):668-677. doi: 10.1002/ijc.29032. Epub 2014 Jul 8.
    • Better contralateral breast cancer risk estimation and alternative options to contralateral prophylactic mastectomy.
    • Davies KR, Cantor SB, Brewster AM.
    • Int J Womens Health. 2015 Feb 4;7:181-7. doi: 10.2147/IJWH.S52380. eCollection 2015.
    • Contralateral prophylactic mastectomy after unilateral breast cancer: a systematic review and meta-analysis.
    • Fayanju OM, Stoll CR, Fowler S, Colditz GA, Margenthaler JA.
    • Ann Surg. 2014 Dec;260(6):1000-10. doi: 10.1097/SLA.0000000000000769.
    • Contralateral prophylactic mastectomy and its association with reduced mortality: evidence for selection bias.
    • Jatoi I, Parsons HM.
    • Breast Cancer Res Treat. 2014 Nov;148(2):389-96. doi: 10.1007/s10549-014-3160-y. Epub 2014 Oct 10.
    • Threshold for genetic testing in women with breast cancer needs to be determined.
    • Basu NN, Barr L, Evans DG, Ross GL.
    • BMJ. 2014 Mar 6;348:g1863. doi: 10.1136/bmj.g1863.
    • Letter

    Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis.

    • Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis.
    • Metcalfe K, Gershman S, Ghadirian P, Lynch HT, Snyder C, Tung N, Kim-Sing C, Eisen A, Foulkes WD, Rosen B, Sun P, Narod SA.
    • BMJ. 2014 Feb 11;348:g226. doi: 10.1136/bmj.g226.

    Comment, Editorial:

    Contralateral mastectomy for women with hereditary breast cancer.

    Letter, Comment:

    Threshold for genetic testing in women with breast cancer needs to be determined.

    Research News:

    Women with BRCA mutation have better survival rates after double mastectomy.

    Press: Bilateral Mastectomy Ups Survival in BRCA Carriers. (Medscape/Reuters)

    • Improved long-term survival with contralateral prophylactic mastectomy among young women.
    • Zeichner SB, Zeichner SB, Ruiz AL, Markward NJ, Rodriguez E.
    • Asian Pac J Cancer Prev. 2014;15(3):1155-62.
    • Review of risk factors for the development of contralateral breast cancer.
    • Lizarraga IM, Sugg SL, Weigel RJ, Scott-Conner CE.
    • Am J Surg. 2013 Nov;206(5):704-8. doi: 10.1016/j.amjsurg.2013.08.002. Epub 2013 Sep 6.
    • Review
    • Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer.
    • Evans DG, Ingham SL, Baildam A, Ross GL, Lalloo F, Buchan I, Howell A.
    • Breast Cancer Res Treat. 2013 Jul;140(1):135-42. doi: 10.1007/s10549-013-2583-1. Epub 2013 Jun 20.
    • Contralateral prophylactic mastectomy: clinical and pathological features from a prospective database.
    • Barry PN, Johnson RR, Harkenrider MM, Freeman AB, Kruse B, Wilson MR, Pan J, Dragun AE.
    • Am J Med Sci. 2012 Dec;344(6):452-6. doi: 10.1097/MAJ.0b013e31824a82ce.
    • Association between contralateral prophylactic mastectomy and breast cancer outcomes by hormone receptor status.
    • Brewster AM, Bedrosian I, Parker PA, Dong W, Peterson SK, Cantor SB, Crosby M, Shen Y.
    • Cancer. 2012 Nov 15;118(22):5637-43. doi: 10.1002/cncr.27574. Epub 2012 Apr 19.