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- Evaluation of AlphaFold Structure-based Protein Stability Prediction on Missense Variations in Cancer.
- Karakoyun HK, Yuksel SK, Amanoglu I, Naserikhojasteh L, Yakicier C, Yesilyurt A, Timucin E, Akyerli CB.
- Front Genet. 2023 Feb 8;14:1052383. doi: 10.3389/fgene.2023.1052383.
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- Hereditary Cancer Syndrome in a Family with Double Mutation in BRIP1 and MUTYH Genes.
- D’Elia G, Caliendo G, Passariello L, Albanese L, Makker J, Molinari AM, Vietri MT.
- Genes (Basel). 2023 Feb 8;14(2):428. doi: 10.3390/genes14020428.
- Case report
- Free Full Text
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- Homologous Recombination Deficiency in Ovarian Cancer: From the Biological Rationale to Current Diagnostic Approaches.
- Mangogna A, Munari G, Pepe F, Maffii E, Giampaolino P, Ricci G, Fassan M, Malapelle U, Biffi S.>
- J Pers Med. 2023 Feb 2;13(2):284. doi: 10.3390/jpm13020284.
- Review
- Free Full Text
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- Beyond BRCA: Patterns of risk-reducing surgery for non-BRCA, homologous recombination repair pathway gene variant carriers.
- Lee SS, Karpel HC, Oh C, Smith J, Pothuri B.
- Gynecol Oncol. 2023 Jan 30;170:234-240. doi: 10.1016/j.ygyno.2022.12.012. Epub ahead of print.
- PMID: 36724586
- PubMed abstract
- Source abstract
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- MR imaging phenotypes and features associated with pathogenic mutation to predict recurrence or metastasis in breast cancer.
- Shao Z, Yu J, Cheng Y, Ma W, Liu P, Lu H.
- BMC Cancer. 2023 Jan 27;23(1):97. doi: 10.1186/s12885-023-10555-5.
- PMID: 36707770
- PubMed abstract
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- Association of Reported Candidate Monogenic Genes With Lung Cancer Risk.
- Rifkin AS, Less EM, Wei J, Shi Z, Zheng SL, Helfand BT, Hulick PJ, Krantz SB, Xu J.
- Clin Lung Cancer. 2023 Jan 26:S1525-7304(23)00009-8. doi: 10.1016/j.cllc.2023.01.005. Epub ahead of print.
- PMID: 36781323
- PubMed abstract
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- Occurrence of variants of unknown clinical significance in genetic testing for hereditary breast and ovarian cancer syndrome and Lynch syndrome: a literature review and analytical observational retrospective cohort study.
- Adam F, Fluri M, Scherz A, Rabaglio M.
- BMC Med Genomics. 2023 Jan 16;16(1):7. doi: 10.1186/s12920-023-01437-7.
- PMID: 36647026
- PubMed abstract
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- Factors that influence the management recommendations breast surgeons provide to women with pathogenic variants in moderate penetrance breast cancer susceptibility genes.
- Vanderwal A, Lewis J, Basil J, Atzinger C, Widmeyer K.
- J Genet Couns. 2023 Jan 15. doi: 10.1002/jgc4.1674. Epub ahead of print.
- PMID: 36642783
- PubMed abstract
- Source abstract
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- Profiling of the genetic features of Chinese patients with gastric cancer with HRD germline mutations in a large-scale retrospective study.
- Zhang C, Zhu D, Qu Y, Shi M, Ma J, Peng Y, Zhu B, Tao H, Ma T, Hou T.
- J Med Genet. 2023 Jan 10:jmg-2022-108816. doi: 10.1136/jmg-2022-108816. Epub ahead of print.
- PMID: 36627197
- PubMed abstract
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- Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial.
- Pujade-Lauraine E, Brown J, Barnicle A, Wessen J, Lao-Sirieix P, Criscione SW, du Bois A, Lorusso D, Romero I, Petru E, Yoshida H, Vergote I, Colombo N, Hietanen S, Provansal M, Schmalfeldt B, Pignata S, Martín Lorente C, Berton D, Runnebaum IB, Ray-Coquard I.
- JCO Precis Oncol. 2023 Jan;7:e2200258. doi: 10.1200/PO.22.00258.
- PMID: 36716415
- PubMed abstract
•• Identifier: NCT02477644: Platine, Avastin and OLAparib in 1st Line (PAOLA-1). (ClinicalTrials.gov . Accessed 2023 Jan 30.)
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- Widespread genomic/molecular alterations of DNA helicases and their clinical/therapeutic implications across human cancer.
- Qin X, Wang J, Wang X, Huang T, Fang Z, Yan L, Fan Y, Xu D.
- Biomed Pharmacother. 2022 Dec 29;158:114193. doi: 10.1016/j.biopha.2022.114193. Epub ahead of print.
- PMID: 36586240
- PubMed abstract
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- Inherited mutations in Chinese patients with upper tract urothelial carcinoma.
- Wu J, Jin S, Gu C, Wei Y, Zhu Y, Necchi A, Shariat SF, Pan J, Gan H, Dai B, Zhang H, Shi G, Zhu Y, Shen Y, Zhu Y, Ye D.
- Cell Rep Med. 2022 Dec 23:100883. doi: 10.1016/j.xcrm.2022.100883. Epub ahead of print.
- PMID: 36630951
- PubMed abstract
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- Genetic testing women with newly diagnosed breast cancer: What criteria are the most predictive of a positive test?
- Metcalfe KA, Narod SA, Eisen A, Poll A, Zamani N, McCready D, Cil TD, Wright FC, Lerner-Ellis J, McCuaig J, Graham T, Sun P, Akbari MR.
- Cancer Med. 2022 Dec 21. doi: 10.1002/cam4.5515. Epub ahead of print.
- PMID: 36544278
- PubMed abstract
- Source abstract
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- A systematic method for detecting abnormal mRNA splicing and assessing its clinical impact in individuals undergoing genetic testing for hereditary cancer syndromes.
- Kamps-Hughes N, Carlton VEH, Fresard L, Osazuwa S, Starks E, Vincent JJ, Albritton S, Nussbaum RL, Nykamp K.
- J Mol Diagn. 2022 Dec 20:S1525-1578(22)00348-8. doi: 10.1016/j.jmoldx.2022.12.002. Epub ahead of print.
- PMID: 36563937
- PubMed abstract
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- Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients.
- Nurmi AK, Suvanto M, Dennis J, Aittomäki K, Blomqvist C, Nevanlinna H.
- Cancers (Basel). 2022 Dec 14;14(24):6158. doi: 10.3390/cancers14246158.
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- Clinical Impact of Next-Generation Sequencing Multi-Gene Panel Highlighting the Landscape of Germline Alterations in Ovarian Cancer Patients.
- Gurioli G, Tedaldi G, Farolfi A, Petracci E, Casanova C, Comerci G, Danesi R, Arcangeli V, Ravegnani M, Calistri D, Zampiga V, Cangini I, Fonzi E, Virga A, Tassinari D, Rosati M, Ulivi P, De Giorgi U.
- Int J Mol Sci. 2022 Dec 13;23(24):15789. doi: 10.3390/ijms232415789.
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- Germline pathogenic variants associated with ovarian cancer: A historical overview.
- Johansen EL, Thusgaard CF, Thomassen M, Boonen SE, Jochumsen KM.
- Gynecol Oncol Rep. 2022 Nov 8 [eCollection 2022 Dec];44:101105. doi: 10.1016/j.gore.2022.101105.
- PMID: 36388756
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
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- Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer.
- Trendowski MR, Sample C, Baird T, Sadeghpour A, Moon D, Ruterbusch JJ, Beebe-Dimmer JL, Cooney KA.
- JCO Precis Oncol. 2022 Nov [2022 Nov 29];6:e2200460. doi: 10.1200/PO.22.00460.
- PMID: 36446039
- PubMed abstract
- Source abstract
•• Research news: Genetic Variants Linked to Prostate Cancer in Black Men Identified. (Inside Precision Medicine)
•• Research news: Genetic Variants Could Predict Prostate Cancer Risk in Black Men. (Inside Precision Medicine)
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- UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2.
- Hanson H, Kulkarni A, Loong L, Kavanaugh G, Torr B, Allen S, Ahmed M, Antoniou AC, Cleaver R, Dabir T, Evans DG, Golightly E, Jewell R, Kohut K, Manchanda R, Murray A, Murray J, Ong KR, Rosenthal AN, Woodward ER, Eccles DM, Turnbull C, Tischkowitz M; Consensus meeting attendees, Lalloo F.
- J Med Genet. 2022 Nov 21:jmg-2022-108898. doi: 10.1136/jmg-2022-108898. Epub ahead of print.
- PMID: 36411032
- PubMed abstract
- Guideline
- Free Full Text
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- Implementation of multigene panel testing for breast and ovarian cancer in South Africa: a step towards excellence in Oncology for the public sector.
- Van Der Merwe NC, Ntaita KS, Stofberg H, Combrink HM, Oosthuizen J, Kotze MJ.
- Front Oncol. 2022 Nov 8;12:938561. doi: 10.3389/fonc.2022.938561.
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- Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center.
- Poliani L, Greco L, Barile M, Buono AD, Bianchi P, Basso G, Giatti V, Genuardi M, Malesci A, Laghi L; Alliance Against Cancer.
- ESMO Open. 2022 Nov 7;7(6):100607. doi: 10.1016/j.esmoop.2022.100607. Epub ahead of print.
- PMID: 36356413
- PubMed abstract
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- Germline and somatic variants in ovarian carcinoma: a next-generation sequencing (NGS) analysis.
- Andrikopoulou A, Zografos E, Apostolidou K, Kyriazoglou T, Papatheodoridi AM, Kaparelou M, Koutsoukos K, Liontos M, Dimopoulos M, Zagouri F.
- Front Oncol. 2022 Oct 31;12:1030786. doi: 10.3389/fonc.2022.1030786.
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- Somatic Inactivation of Breast Cancer Predisposition Genes in Tumours Associated with Pathogenic Germline Variants.
- Lim BWX, Li N, Mahale S, Mcinerny S, Zethoven M, Rowley SM, Huynh J, Wang T, Lee JEA, Friedman M, Devereux L, Scott RJ, Sloan EK, James PA, Campbell IG.
- J Natl Cancer Inst. 2022 Oct 31:djac196. doi: 10.1093/jnci/djac196. Epub ahead of print.
- PMID: 36315097
- PubMed abstract
- Source abstract
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- Mutational landscape of DNA damage response deficiency-related genes and its association with immune biomarkers in esophageal squamous cell carcinoma.
- Chen G, Zhu YJ, Chen J, Miao F, Wu N, Song Y, Mao BB, Wang SZ, Xu F, Chen ZM.
- Neoplasma. 2022 Oct 21:220721N738. doi: 10.4149/neo_2022_220721N738. Epub ahead of print.
- PMID: 36264776
- PubMed abstract
- Source abstract
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- Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline.
- Sessa C, Balmaña J, Bober SL, Cardoso MJ, Colombo N, Curigliano G, Domchek SM, Evans DG, Fischerova D, Harbeck N, Kuhl C, Lemley B, Levy-Lahad E, Lambertini M, Ledermann JA, Loibl S, Phillips KA, Shimon P; ESMO Guidelines Committee.
- Ann Oncol. 2022 Oct 19:S0923-7534(22)04193-X. doi: 10.1016/j.annonc.2022.10.004. Epub ahead of print.
- PMID: 36307055
- PubMed abstract
- Guideline
- Free Full Text
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- Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania.
- Felbor U, Bülow R, Schmutzler RK, Rath M.
- Healthcare (Basel). 2022 Oct 13;10(10):2021. doi: 10.3390/healthcare10102021.
- PMID: 36292468
- PubMed abstract
- Source abstract
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- Moderate-Risk Genes for Hereditary Ovarian Cancers Involved in the Homologous Recombination Repair Pathway.
- Abe A, Imoto I, Ueki A, Nomura H, Kanao H.
- Int J Mol Sci. 2022 Oct 4;23(19):11790. doi: 10.3390/ijms231911790.
- PMID: 36233090
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
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- Low BRCA1 and BRCA2 Germline Mutation Rates in a French-Canadian Population with a Diagnosis of Epithelial Tubo-Ovarian Carcinoma.
- Bernard J, Mehros W, Gregoire J, Douville P, Renaud MC, Sebastianelli A, Langlais EL, Plante M.
- J Obstet Gynaecol Can. 2022 Oct;44(10):1047-1053. doi: 10.1016/j.jogc.2022.06.005. Epub 2022 Jun 30.
- PMID: 35779836
- PubMed abstract
- Source abstract
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- High detection rate from genetic testing in BRCA-negative women with familial epithelial ovarian cancer.
- Flaum N, Crosbie EJ, Edmondson R, Woodward ER, Lalloo F, Smith MJ, Schlecht H, Evans DG.
- Genet Med. 2022 Sep 28:S1098-3600(22)00913-3. doi: 10.1016/j.gim.2022.08.022. Epub ahead of print.
- PMID: 36169650
- PubMed abstract
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- Who Should Have Multigene Germline Testing for Hereditary Cancer?
- Savage SA.
- J Clin Oncol. 2022 Sep 27:JCO2201691. doi: 10.1200/JCO.22.01691. Epub ahead of print.
- PMID: 36166722
- PubMed abstract
- Source abstract
- Commentary
- Free Full Text
Original research:
Development and Validation of the PREMMplus Model for Multigene Hereditary Cancer Risk Assessment.
- PMID: 35960913
- PubMed abstract
- Source abstract
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- Germline Variants in 32 Cancer-Related Genes among 700 Chinese Breast Cancer Patients by Next-Generation Sequencing: A Clinic-Based, Observational Study.
- Yang L, Xie F, Liu C, Zhao J, Hu T, Wu J, Zhao X, Wang S.
- Int J Mol Sci. 2022 Sep 24;23(19):11266. doi: 10.3390/ijms231911266.
- PMID: 36232564
- PubMed abstract
- Source abstract
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- Analysis of rare disruptive germline mutations in 2,135 enriched BRCA-negative breast cancers excludes additional high-impact susceptibility genes.
- Loveday C, Garrett A, Law P, Hanks S, Poyastro-Pearson E, Adlard JW, Barwell J, Berg J, Brady AF, Brewer C, Chapman C, Cook J, Davidson R, Donaldson A, Douglas F, Greenhalgh L, Henderson A, Izatt L, Kumar A, Lalloo F, Miedzybrodzka Z, Morrison PJ, Paterson J, Porteous M, Rogers MT, Walker L; Breast and Ovarian Cancer Susceptibility Collaboration, Eccles D, Evans DG, Snape K, Hanson H, Houlston RS, Turnbull C.
- Ann Oncol. 2022 Sep 16:S0923-7534(22)04143-6. doi: 10.1016/j.annonc.2022.09.152. Epub ahead of print.
- PMID: 36122798
- PubMed abstract
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- Targeted Sequencing of Germline Breast Cancer Susceptibility Genes for Discovering Pathogenic/Likely Pathogenic Variants in the Jakarta Population.
- Panigoro SS, Paramita RI, Siswiandari KM, Fadilah F.
- Diagnostics (Basel). 2022 Sep 16;12(9):2241. doi: 10.3390/diagnostics12092241.
- PMID: 36140642
- PubMed abstract
- Source abstract
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- Other Primary Malignancies in Patients with Breast Cancer Who Undergo Germline Panel Testing.
- Murphy BL, Yi M, Gutierrez Barrera AM, Tripathy D, Hunt KK, Arun BK.
- Ann Surg Oncol. 2022 Sep 12. doi: 10.1245/s10434-022-12468-2. Epub ahead of print.
- PMID: 36094691
- PubMed abstract
- Source abstract
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- Somatic tumor mutations in moderate risk cancer genes: Targets for germline confirmatory testing.
- Llorin H, Graf M, Chun N, Ford J.
- Cancer Genet. 2022 Sep 6;268-269:22-27. doi: 10.1016/j.cancergen.2022.09.001. Epub ahead of print.
- PMID: 36116289
- PubMed abstract
- Source abstract
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- Online Tool IDs People With Genetic Mutations Linked to Cancer.
- Brooks M.
- Medscape Oncology. 2022 Aug 30.
- Research news
- Free Full Text
Original research:
Development and Validation of the PREMMplus Model for Multigene Hereditary Cancer Risk Assessment.
- PMID: 35960913
- PubMed abstract
- Source abstract
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- Risk-reducing surgery in unaffected individuals receiving cancer genetic testing in an integrated health care system.
- Knerr S, Guo B, Mittendorf KF, Feigelson HS, Gilmore MJ, Jarvik GP, Kauffman TL, Keast E, Lynch FL, Muessig KR, Okuyama S, Veenstra DL, Zepp JM, Goddard KAB, Devine B.
- Cancer. 2022 Aug 15;128(16):3090-3098. doi: 10.1002/cncr.34349. Epub 2022 Jun 9.
- PMID: 35679147
- PubMed abstract
- Source abstract
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- Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients.
- Ceyhan-Birsoy O, Jayakumaran G, Kemel Y, Misyura M, Aypar U, Jairam S, Yang C, Li Y, Mehta N, Maio A, Arnold A, Salo-Mullen E, Sheehan M, Syed A, Walsh M, Carlo M, Robson M, Offit K, Ladanyi M, Reis-Filho JS, Stadler ZK, Zhang L, Latham A, Zehir A, Mandelker D.
- Genome Med. 2022 Aug 15;14(1):92. doi: 10.1186/s13073-022-01101-2.
- PMID: 35971132
- PubMed abstract
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- Concordance Between Genomic Alterations Detected by Tumor and Germline Sequencing: Results from a Tertiary Care Academic Center Molecular Tumor Board.
- Green MF, Watson CH, Tait S, He J, Pavlick DC, Frampton G, Riedel J, Plichta JK, Armstrong AJ, Previs RA, Kauff N, Strickler JH, Datto MB, Berchuck A, Menendez CS.
- Oncologist. 2022 Aug 13:oyac164. doi: 10.1093/oncolo/oyac164. Epub ahead of print.
- PMID: 35962742
- PubMed abstract
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- A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma.
- Crabb SJ, Hussain S, Soulis E, Hinsley S, Dempsey L, Trevethan A, Song Y, Barber J, Frew J, Gale J, Faust G, Brock S, McGovern U, Parikh O, Enting D, Sundar S, Ratnayake G, Lees K, Birtle AJ, Powles T, Jones RJ.
- J Clin Oncol. 2022 Aug 12:JCO2200405. doi: 10.1200/JCO.22.00405. Epub ahead of print.
- PMID: 35960902
- PubMed abstract
- Source abstract
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- Development and Validation of the PREMMplus Model for Multigene Hereditary Cancer Risk Assessment.
- Yurgelun MB, Uno H, Furniss CS, Ukaegbu C, Horiguchi M, Yussuf A, LaDuca H, Chittenden A, Garber JE, Syngal S.
- J Clin Oncol. 2022 Aug 12:JCO2200120. doi: 10.1200/JCO.22.00120. Epub ahead of print.
- PMID: 35960913
- PubMed abstract
- Source abstract
Commentary:
Who Should Have Multigene Germline Testing for Hereditary Cancer?
- PMID: 36166722
- PubMed abstract
- Free Full Text
Research news: Online Tool IDs People With Genetic Mutations Linked to Cancer. (Medscape Oncology)
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- BRCA Mutations in Ovarian and Prostate Cancer: Bench to Bedside.
- Boussios S, Rassy E, Moschetta M, Ghose A, Adeleke S, Sanchez E, Sheriff M, Chargari C, Pavlidis N.
- Cancers (Basel). 2022 Aug 11;14(16):3888. doi: 10.3390/cancers14163888.
- PMID: 36010882
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
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- Multi-gene panel testing increases germline predisposing mutations' detection in a cohort of breast/ovarian cancer patients from Southern Italy.
- Nunziato M, Di Maggio F, Pensabene M, Esposito MV, Starnone F, De Angelis C, Calabrese A, D'Aiuto M, Botti G, De Placido S, D'Argenio V, Salvatore F.
- Front Med (Lausanne). 2022 Aug 11;9:894358. doi: 10.3389/fmed.2022.894358.
- PMID: 36035419
- PubMed abstract
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- What are the considerations in patient selection and timing of risk-reducing mastectomy?
- Pederson HJ, Kurian AW, Al Hilli Z.
- Cleve Clin J Med. 2022 Aug 1;89(8):442-444. doi: 10.3949/ccjm.89a.21114.
- PMID: 35914935
- PubMed abstract
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- Influence of germline test results on surgical decision making in women with invasive breast cancer.
- Vargason AB, Turner CE, Shriver CD, Ellsworth RE.
- Cancer Genet. 2022 Aug;266-267:81-85. doi: 10.1016/j.cancergen.2022.07.003. Epub 2022 Jul 13.
- PMID:35868102
- PubMed abstract
- Source abstract
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- Multi-Gene Mutation Profiling by Targeted Next-Generation Sequencing in Premenopausal Breast Cancer.
- Zografos E, Andrikopoulou A, Papatheodoridi AM, Kaparelou M, Bletsa G, Liontos M, Dimopoulos MA, Zagouri F.
- Genes (Basel). 2022 Jul 29;13(8):1362. doi: 10.3390/genes13081362.
- PMID: 36011273
- PubMed abstract
- Source abstract
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- Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.
- Dumont M, Weber-Lassalle N, Joly-Beauparlant C, Ernst C, Droit A, Feng BJ, Dubois S, Collin-Deschesnes AC, Soucy P, Vallée M, Fournier F, Lemaçon A, Adank MA, Allen J, Altmüller J, Arnold N, Ausems MGEM, Berutti R, Bolla MK, Bull S, Carvalho S, Cornelissen S, Dufault MR, Dunning AM, Engel C, Gehrig A, Geurts-Giele WRR, Gieger C, Green J, Hackmann K, Helmy M, Hentschel J, Hogervorst FBL, Hollestelle A, Hooning MJ, Horváth J, Ikram MA, Kaulfuß S, Keeman R, Kuang D, Luccarini C, Maier W, Martens JWM, Niederacher D, Nürnberg P, Ott CE, Peters A, Pharoah PDP, Ramirez A, Ramser J, Riedel-Heller S, Schmidt G, Shah M, Scherer M, Stäbler A, Strom TM, Sutter C, Thiele H, van Asperen CJ, van der Kolk L, van der Luijt RB, Volk AE, Wagner M, Waisfisz Q, Wang Q, Wang-Gohrke S, Weber BHF, Genome Of The Netherlands Project, Ghs Study Group, Devilee P, Tavtigian S, Bader GD, Meindl A, Goldgar DE, Andrulis IL, Schmutzler RK, Easton DF, Schmidt MK, Hahnen E, Simard J.
- Cancers (Basel). 2022 Jul 11;14(14):3363. doi: 10.3390/cancers14143363.
- PMID: 35884425
- PubMed abstract
- Source abstract
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- Epithelial Ovarian Cancer: Providing Evidence of Predisposition Genes.
- Shah S, Cheung A, Kutka M, Sheriff M, Boussios S.
- Int J Environ Res Public Health. 2022 Jul 1;19(13):8113. doi: 10.3390/ijerph19138113.
- PMID: 35805770
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- Genetic testing in prostate cancer management: Considerations informing primary care.
- Giri VN, Morgan TM, Morris DS, Berchuck JE, Hyatt C, Taplin ME.
- CA Cancer J Clin. 2022 Jul;72(4):360-371. doi: 10.3322/caac.21720. Epub 2022 Feb 24.
- PMID: 35201622
- PubMed abstract
- Source abstract
- Review
- Free Full Text
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- Germline Pathogenic Variant Prevalence Among Latin American and US Hispanic Individuals Undergoing Testing for Hereditary Breast and Ovarian Cancer: A Cross-Sectional Study.
- Ossa Gomez CA, Achatz MI, Hurtado M, Sanabria-Salas MC, Sullcahuaman Y, Chávarri-Guerra Y, Dutil J, Nielsen SM, Esplin ED, Michalski ST, Bristow SL, Hatchell KE, Nussbaum RL, Pineda-Alvarez DE, Ashton-Prolla P.
- JCO Glob Oncol. 2022 Jul;8:e2200104. doi: 10.1200/GO.22.00104.
- PMID: 35867948
- PubMed abstract
- Source abstract
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- Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors.
- Lee A, Yang X, Tyrer J, Gentry-Maharaj A, Ryan A, Mavaddat N, Cunningham AP, Carver T, Archer S, Leslie G, Kalsi J, Gaba F, Manchanda R, Gayther S, Ramus SJ, Walter FM, Tischkowitz M, Jacobs I, Menon U, Easton DF, Pharoah P, Antoniou AC.
- J Med Genet. 2022 Jul;59(7):632-643. doi: 10.1136/jmedgenet-2021-107904. Epub 2021 Nov 29.
- PMID: 34844974
- PubMed abstract
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- Multigene Panel Testing in Turkish Hereditary Cancer Syndrome Patients.
- Arslan Ates E, Turkyilmaz A, Alavanda C, Yildirim O, Guney AI.
- Medeni Med J. 2022 Jun 23;37(2):150-158. doi: 10.4274/MMJ.galenos.2022.22556.
- PMID: 35734982
- PubMed abstract
- Source abstract
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- TRACEBACK: Testing of Historical Tubo-Ovarian Cancer Patients for Hereditary Risk Genes as a Cancer Prevention Strategy in Family Members.
- Delahunty R, Nguyen L, Craig S, Creighton B, Ariyaratne D, Garsed DW, Christie E, Fereday S, Andrews L, Lewis A, Limb S, Pandey A, Hendley J, Traficante N, Carvajal N, Spurdle AB, Thompson B, Parsons MT, Beshay V, Volcheck M, Semple T, Lupat R, Doig K, Yu J, Chen XQ, Marsh A, Love C, Bilic S, Beilin M, Nichols CB, Greer C, Lee YC, Gerty S, Gill L, Newton E, Howard J, Williams R, Norris C, Stephens AN, Tutty E, Smyth C, O'Connell S, Jobling T, Stewart CJR, Tan A, Fox SB, Pachter N, Li J, Ellul J, Mir Arnau G, Young MA, Gordon L, Forrest L, Harris M, Livingstone K, Hill J, Chenevix-Trench G, Cohen PA, Webb PM, Friedlander M, James P, Bowtell D, Alsop K; Australian Ovarian Cancer Study, Ovarian Cancer Prognosis and Lifestyle Study and the TRACEBACK Study.
- J Clin Oncol. 2022 Jun 20;40(18):2036-2047. doi: 10.1200/JCO.21.02108. Epub 2022 Mar 9.
- PMID: 35263119
- PubMed abstract
- Source abstract
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- The mutation landscape of multiple cancer predisposition genes in Chinese familial/hereditary breast cancer families.
- Dong L, Zhang H, Zhang H, Ye Y, Cheng Y, Li L, Wei L, Han L, Cao Y, Li S, Hao X, Liu J, Yu J.
- Cancer Biol Med. 2021 Sep 28 [2022 Jun 15];19(6):850–70. doi: 10.20892/j.issn.2095-3941.2021.0011. Epub ahead of print.
- PMID: 34570441
- PubMed abstract
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- Leptomeningeal disease in BRIP1-mutated pancreatic adenocarcinoma.
- Yim E, Leung D.
- BMJ Case Rep. 2022 Jun 8;15(6):e249837. doi: 10.1136/bcr-2022-249837.
- PMID: 35675963
- PubMed abstract
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Subject: BRIP1 Mutation
Subject: Register for the November Cancer SIG Journal Club
Subject: searching for BRIP1 article
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Subject: RAD50 Positive Letter
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Comments on NSGC Discussion Forum Cancer SIG
Subject: PALB2 and Ovarian Cancer
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