Specific breast cancer subtypes or pathology associated with given genes/mutations
List was last updated on
.-
- Sacituzumab govitecan and radiotherapy in metastatic, triple-negative, and BRCA-mutant breast cancer patient with active brain metastases: A case report.
- di Mauro P, Schivardi G, Pedersini R, Laini L, Esposito A, Amoroso V, Laganà M, Grisanti S, Cosentini D, Berruti A.
- Front Oncol. 2023 Feb 20;13:1139372. doi: 10.3389/fonc.2023.1139372.
- Case report
- Free Full Text
-
- A matched case-control study of the prognosis of early breast cancer in patients with Li-Fraumeni syndrome (BREAST TP53).
- Petry V, Colombo Bonadio R, Testa L, Cohn DJBH, Cagnacci A, Campos RG, Cândida Bv Fragoso M, del Pilar Estevez-Diz M.
- Breast. 2023 Feb 6:S0960-9776(23)00025-5. doi: 10.1016/j.breast.2023.02.002. Epub ahead of print.
-
- Hereditary Diffuse Gastric Cancer.
- Decourtye-Espiard L, Guilford P.
- Gastroenterology. 2023 Feb 3:S0016-5085(23)00110-5. doi: 10.1053/j.gastro.2023.01.038. Epub ahead of print.
- PMID: 36740198
- PubMed abstract
- Source abstract
-
- Distinct breast cancer phenotypes in BRCA 1/2 carriers based on ER status.
- Rosenberg S, Devir M, Kaduri L, Grinshpun A, Miner V, Hamburger T, Granit A, Nissan A, Maymon O, Peretz T.
- Breast Cancer Res Treat. 2023 Feb 2. doi: 10.1007/s10549-022-06851-6. Epub ahead of print.
- PMID: 36729248
- PubMed abstract
- Source abstract
-
- Germline TP53 pathogenic variants and breast cancer: A narrative review.
- Blondeaux E, Arecco L, Punie K, Graffeo R, Toss A, De Angelis C, Trevisan L, Buzzatti G, Linn SC, Dubsky P, Cruellas M, Partridge AH, Balmaña J, Paluch-Shimon S, Lambertini M.
- Cancer Treat Rev. 2023 Jan 31;114:102522. doi: 10.1016/j.ctrv.2023.102522. Epub ahead of print.
- PMID: 36739824
- PubMed abstract
- Review
- Free Full Text
-
- Whole exome sequencing and replication for breast cancer among Hispanic/Latino women identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer.
- Nierenberg JL, Adamson AW, Hu D, Huntsman S, Patrick C, Li M, Steele L, Tong B, Shieh Y, Fejerman L, Gruber SB, Haiman CA, John EM, Kushi LH, Torres-Mejía G, Ricker C, Weitzel JN, Ziv E, Neuhausen SL.
- medRxiv [Preprint]. 2023 Jan 28:2023.01.25.23284924. doi: 10.1101/2023.01.25.23284924.
- PMID: 36747679
- PubMed abstract
- Source abstract
- Preprint
- Free PMC article
- Free Full Text
-
- MR imaging phenotypes and features associated with pathogenic mutation to predict recurrence or metastasis in breast cancer.
- Shao Z, Yu J, Cheng Y, Ma W, Liu P, Lu H.
- BMC Cancer. 2023 Jan 27;23(1):97. doi: 10.1186/s12885-023-10555-5.
- PMID: 36707770
- PubMed abstract
-
- FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women.
- Figlioli G, Billaud A, Ahearn TU, Antonenkova NN, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Blok MJ, Bogdanova NV, Bonanni B, Burwinkel B, Camp NJ, Campbell A, Castelao JE, Cessna MH, Chanock SJ; NBCS Collaborators; Czene K, Devilee P, Dörk T, Engel C, Eriksson M, Fasching PA, Figueroa JD, Gabrielson M, Gago-Dominguez M, García-Closas M, González-Neira A, Grassmann F, Guénel P, Gündert M, Hadjisavvas A, Hahnen E, Hall P, Hamann U, Harrington PA, He W, Hillemanns P, Hollestelle A, Hooning MJ, Hoppe R, Howell A, Humphreys K; KConFab Investigators; Jager A, Jakubowska A, Khusnutdinova EK, Ko YD, Kristensen VN, Lindblom A, Lissowska J, Lubiński J, Mannermaa A, Manoukian S, Margolin S, Mavroudis D, Newman WG, Obi N, Panayiotidis MI, Rashid MU, Rhenius V, Rookus MA, Saloustros E, Sawyer EJ, Schmutzler RK, Shah M, Sironen R, Southey MC, Suvanto M, Tollenaar RAEM, Tomlinson I, Truong T, van der Kolk LE, van Veen EM, Wappenschmidt B, Yang XR, Bolla MK, Dennis J, Dunning AM, Easton DF, Lush M, Michailidou K, Pharoah PDP, Wang Q, Adank MA, Schmidt MK, Andrulis IL, Chang-Claude J, Nevanlinna H, Chenevix-Trench G, Evans DG, Milne RL, Radice P, Peterlongo P.
- Eur J Hum Genet. 2023 Jan 27. doi: 10.1038/s41431-022-01257-w. Epub ahead of print.
- PMID: 36707629
- PubMed abstract
-
- Das hereditäre diffuse Magenkarzinom [Hereditary diffuse gastric cancer].
- Knipper K, Fuchs HF, Alakus H, Bruns CJ, Schmidt T.
- Chirurgie (Heidelb). 2023 Jan 26. German. doi: 10.1007/s00104-023-01806-z. Epub ahead of print.
- PMID: 36700973
- PubMed abstract
- Source abstract
-
- Risk of seizures in a population of women with BRCA-positive metastatic breast cancer from an electronic health record database in the United States.
- Liede A, Sebby W, Miriyala AKR, Potluri R, Mazumder D, Ghosh A, Papademetriou E, Kilpatrick R, Tyczynski JE.
- BMC Cancer. 2023 Jan 24;23(1):78. doi: 10.1186/s12885-023-10554-6.
- PMID: 36690978
- PubMed abstract
-
- Importance of timely genetics services and critical evaluation of diagnosis and reported family history when assessing for hereditary cancer syndromes. [2022 CGA-IGC Annual Meeting: The collaborative group of the Americas on Inherited Gastrointestinal Cancer November 11–13, 2022.]
- Malca S.
- Fam Cancer. [P-08: Case Reports» Case Series on any topic.] 2023 Jan 23. doi: 10.1007/s10689-022-00324-x. Epub ahead of print.
-
- Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival.
- Lopes Cardozo JMN, Andrulis IL, Bojesen SE, Dörk T, Eccles DM, Fasching PA, Hooning MJ, Keeman R, Nevanlinna H, Rutgers EJT, Easton DF, Hall P, Pharoah PDP, van 't Veer LJ, Schmidt MK; Breast Cancer Association Consortium and MINDACT Collaborators.
- J Clin Oncol. 2023 Jan 23:JCO2201978. doi: 10.1200/JCO.22.01978. Epub ahead of print.
- PMID: 36689693
- PubMed abstract
- Source abstract
-
- Guideline-Based, Multi-Gene Panel Germline Genetic Testing for at-Risk Patients with Breast Cancer.
- Abdel-Razeq H, Abujamous L, Al-Azzam K, Abu-Fares H, Bani Hani H, Alkyam M, Sharaf B, Elemian S, Tamimi F, Abuhijla F, Edaily S, Salama O, Abdulelah H, Daoud R, Abubaker M, Al-Atary A.
- Breast Cancer (Dove Med Press). 2023 Jan 13;15:1-10. doi: 10.2147/BCTT.S394092.
- PMID: 36660366
- PubMed abstract
-
- Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2.
- Yadav S, Boddicker NJ, Na J, Polley EC, Hu C, Hart SN, Gnanaolivu RD, Larson N, Holtegaard S, Huang H, Dunn CA, Teras LR, Patel AV, Lacey JV, Neuhausen SL, Martinez E, Haiman C, Chen F, Ruddy KJ, Olson JE, John EM, Kurian AW, Sandler DP, O'Brien KM, Taylor JA, Weinberg CR, Anton-Culver H, Ziogas A, Zirpoli G, Goldgar DE, Palmer JR, Domchek SM, Weitzel JN, Nathanson KL, Kraft P, Couch FJ.
- J Clin Oncol. 2023 Jan 9:JCO2201239. doi: 10.1200/JCO.22.01239. Epub ahead of print.
- PMID: 36623243
- PubMed abstract
-
- The Contribution of Germline Pathogenic Variants in Breast Cancer Genes to Contralateral Breast Cancer Risk in BRCA1/BRCA2/PALB2-Negative Women.
- Larionov A, Fewings E, Redman J, Goldgraben M, Clark G, Boice J, Concannon P, Bernstein J, Conti DV, the WECARE Study Collaborative Group, Tischkowitz M.
- Cancers (Basel). 2023 Jan 8;15(2):415. doi: 10.3390/cancers15020415.
-
- Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations.
- Kim J, Jeong K, Jun H, Kim K, Bae JM, Song MG, Yi H, Park S, Woo GU, Lee DW, Kim TY, Lee KH, Im SA.
- Hum Genomics. 2023 Jan 6;17(1):2. doi: 10.1186/s40246-022-00447-3.
- PMID: 36604691
- PubMed abstract
-
- Genetic, Surgical and Oncological Approach to Breast Cancer, with BRCA1, BRCA2, CDH1, PALB2, PTEN and TP53 Variants.
- Subaşıoğlu A, Güç ZG, Gür EÖ, Tekindal MA, Atahan MK.
- Eur J Breast Health. 2023 Jan 1;19(1):55-69. doi: 10.4274/ejbh.galenos.2022.2022-7-2.
- PMID: 36605468
- PubMed abstract
-
- Cancer Risk Associated With PTEN Pathogenic Variants Identified Using Multigene Hereditary Cancer Panel Testing.
- Cummings S, Alfonso A, Hughes E, Kucera M, Mabey B, Singh N, Eng C.
- JCO Precis Oncol. 2023 Jan;7:e2200415. doi: 10.1200/PO.22.00415.
- PMID: 36634299
- PubMed abstract
-
- Frequency of Pathogenic Germline Mutations in Early and Late Onset Familial Breast Cancer Patients Using Multi-Gene Panel Sequencing: An Egyptian Study.
- Nassar A, Zekri ARN, Kamel MM, Elberry MH, Lotfy MM, Seadawy MG, Hassan ZK, Soliman HK, Lymona AM, El-Din Youssef AS.
- Genes (Basel). 2022 Dec 29;14(1):106. doi: 10.3390/genes14010106.
-
- Effectiveness of Secondary Risk-Reducing Strategies in Patients With Unilateral Breast Cancer With Pathogenic Variants of BRCA1 and BRCA2 Subjected to Breast-Conserving Surgery: Evidence-Based Simulation Study.
- Maksimenko J, Rodrigues PP, Nakazawa-Miklaševiča M, Pinto D, Miklaševičs E, Trofimovičs G, Gardovskis J, Cardoso F, Cardoso MJ.
- JMIR Form Res. 2022 Dec 29;6(12):e37144. doi: 10.2196/37144.
- PMID: 36580360
- PubMed abstract
-
- Genetic testing women with newly diagnosed breast cancer: What criteria are the most predictive of a positive test?
- Metcalfe KA, Narod SA, Eisen A, Poll A, Zamani N, McCready D, Cil TD, Wright FC, Lerner-Ellis J, McCuaig J, Graham T, Sun P, Akbari MR.
- Cancer Med. 2022 Dec 21. doi: 10.1002/cam4.5515. Epub ahead of print.
- PMID: 36544278
- PubMed abstract
- Source abstract
-
- Deep learning identifies morphological patterns of homologous recombination deficiency in luminal breast cancers from whole slide images.
- Lazard T, Bataillon G, Naylor P, Popova T, Bidard FC, Stoppa-Lyonnet D, Stern MH, Decencière E, Walter T, Vincent-Salomon A..
- Cell Rep Med. 2022 Dec 20;3(12):100872. doi: 10.1016/j.xcrm.2022.100872. Epub 2022 Dec 13.
- PMID: 36516847
- PubMed abstract
•• Commentary:
HRD-related morphology discovery in breast cancer by controlling for confounding factors.
- PMID: 36543118
- PubMed abstract
- Source abstract
-
- Clinicopathological features, genetic alterations, and BRCA1 promoter methylation in Japanese male patients with breast cancer.
- Shimomura A, Yoshida M, Kubo T, Yamashita S, Noguchi E, Nagayama A, Hanamura T, Okazaki M, Mukohara T, Tsuruga A, Tanaka K, Kawamura Y, Higuchi T, Takahashi Y, Kurozumi S, Hayashida T, Ichikawa H, Ushijima T, Suto A.
- Breast Cancer Res Treat. 2022 Dec 9. doi: 10.1007/s10549-022-06822-x. Epub ahead of print.
- PMID: 36494460
- PubMed abstract
-
- BRCA-CRisk: A Contralateral Breast Cancer Risk Prediction Model for BRCA Carriers.
- Sun J, Chu F, Pan J, Zhang Y, Yao L, Chen J, Hu L, Zhang J, Xu Y, Wang X, Cao W, Xie Y.
- J Clin Oncol. 2022 Dec 8:JCO2200833. doi: 10.1200/JCO.22.00833. Epub ahead of print.
- PMID: 36480783
- PubMed abstract
- Source abstract
-
- Sociodemographic, Clinical, and Variation Outcomes for Breast Cancer and Breast Cancer-Related Mutations in a Ten-Year Cohort From Neiva, Huila, Colombia.
- Olaya J, Sanjuan J, Torres-Lopez D, Olaya L, Gutierrez-Vargas M, Olaya G, Olaya JD.
- Cureus. 2022 Dec 6;14(12):e32257. doi: 10.7759/cureus.32257.
- PMID: 36620844
- PubMed abstract
-
- Hereditary breast cancer: syndromes, tumour pathology and molecular testing.
- Sokolova A, Johnstone KJ, McCart Reed AE, Simpson PT, Lakhani SR.
- Histopathology. 2022 Dec 5. doi: 10.1111/his.14808. Epub ahead of print.
- PMID: 36468211
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- Comprehensive clinical characterization of patients with BRCA1: c.5017_5019del germline variant.
- Bang YJ, Kwon WK, Kim JW, Lee JE, Jung BY, Kim M, Kim J, An J, Jung SP, Kim HK, Kim Z, Youn HJ, Ryu JM, Kim SW; Korean Hereditary Breast Cancer Study Group.
- Ann Surg Treat Res. 2022 Dec;103(6):323-330. doi: 10.4174/astr.2022.103.6.323. Epub 2022 Dec 8.
- PMID: 36601340
- PubMed abstract
- Source abstract
-
- Differential involvement of germline pathogenic variants in breast cancer genes between DCIS and low-grade invasive cancers.
- Evans DG, Sithambaram S, van Veen EM, Burghel GJ, Schlecht H, Harkness EF, Byers H, Ellingford JM, Gandhi A, Howell SJ, Howell A, Forde C, Lalloo F, Newman WG, Smith MJ, Woodward ER.
- J Med Genet. 2022 Nov 28:jmg-2022-108790. doi: 10.1136/jmg-2022-108790. Epub ahead of print.
- PMID: 36442995
- PubMed abstract
- Source abstract
-
- The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in BRCA1/2 Negative and Breast Cancer Susceptibility.
- Ben Aissa-Haj J, Pinheiron H, Cornelis F, Sebai M, Meseure D, Briaux A, Berteaux P, Lefol C, Des Guetz G, Trassard M, Stevens D, Vialard F, Bieche I, Noguès C, Tang R, Oliveira C, Stoppat-Lyonnet D, Lidereau R, Rouleau E.
- Genes (Basel). 2022 Nov 25;13(12):2213. doi: 10.3390/genes13122213.
-
- Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes.
- Garcia-Pelaez J, Barbosa-Matos R, Lobo S, Dias A, Garrido L, Castedo S, Sousa S, Pinheiro H, Sousa L, Monteiro R, Maqueda JJ, Fernandes S, Carneiro F, Pinto N, Lemos C, Pinto C, Teixeira MR, Aretz S, Bajalica-Lagercrantz S, Balmaña J, Blatnik A, Benusiglio PR, Blanluet M, Bours V, Brems H, Brunet J, Calistri D, Capellá G, Carrera S, Colas C, Dahan K, de Putter R, Desseignés C, Domínguez-Garrido E, Egas C, Evans DG, Feret D, Fewings E, Fitzgerald RC, Coulet F, Garcia-Barcina M, Genuardi M, Golmard L, Hackmann K, Hanson H, Holinski-Feder E, Hüneburg R, Krajc M, Lagerstedt-Robinson K, Lázaro C, Ligtenberg MJL, Martínez-Bouzas C, Merino S, Michils G, Novakovic S, Patiño-García A, Ranzani GN, Schröck E, Silva I, Silveira C, Soto JL, Spier I, Steinke-Lange V, Tedaldi G, Tejada MI, Woodward ER, Tischkowitz M, Hoogerbrugge N, Oliveira C.
- Lancet Oncol. 2022 Nov 24:S1470-2045(22)00643-X. doi: 10.1016/S1470-2045(22)00643-X. Epub ahead of print.
-
- Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers.
- Ballot E, Galland L, Mananet H, Boidot R, Arnould L, Desmoulins I, Mayeur D, Kaderbhai C, Ilie S, Hennequin A, Bergeron A, Derangère V, Ghiringhelli F, Truntzer C, Ladoire S.
- Breast Cancer Res. 2022 Nov 18;24(1):80. doi: 10.1186/s13058-022-01572-6.
- PMID: 36401316
- PubMed abstract
-
- Avelumab Plus Talazoparib in Patients With Advanced Solid Tumors: The JAVELIN PARP Medley Nonrandomized Controlled Trial.
- Yap TA, Bardia A, Dvorkin M, Galsky MD, Beck JT, Wise DR, Karyakin O, Rubovszky G, Kislov N, Rohrberg K, Joy AA, Telli ML, Schram AM, Conte U, Chappey C, Stewart R, Stypinski D, Michelon E, Cesari R, Konstantinopoulos PA.
- JAMA Oncol. 2022 Nov 17. doi: 10.1001/jamaoncol.2022.5228. Epub ahead of print.
- PMID: 36394849
- PubMed abstract
•• Identifier: NCT03330405: Javelin Parp Medley: Avelumab Plus Talazoparib In Locally Advanced Or Metastatic Solid Tumors. (ClinicalTrials.gov . Accessed 2022 Nov 19.)
•• Commentary:
Combining PARP Inhibitor With Immunotherapy-Does the Promise of Preclinical Data Translate to Clinic?
- PMID: 36394835
- PubMed abstract
- Source abstract
-
- Reproductive risk factors associated with breast cancer in young women by molecular subtype.
- Ruddy KJ, Vierkant RA, Jahan N, Higgins A, Partridge A, Larson N, Radisky DC, Couch F, Olson J, Sherman ME.
- Breast. 2022 Nov 9;66:272-277. doi: 10.1016/j.breast.2022.11.004. Epub ahead of print.
- PMID: 36375388
- PubMed abstract
-
- Exquisitely Platinum-Sensitive Triple-Negative Breast Cancer, Time for BRCA Methylation Testing?
- Tan TJ, Fink JL, Tay TK, Jaradi B, Stone N, Waring P, Koo KM, Tan PH, Tan DS, Dent RA.
- JCO Precis Oncol. [2022 Nov 3];6:e2200309. doi: 10.1200/PO.22.00309.
- PMID: 36331241
- PubMed abstract
- Source abstract
-
- BRCA1/2 Mutation Testing in Patients with HER2-Negative Advanced Breast Cancer: Real-World Data from the United States, Europe, and Israel.
- Mahtani R, Niyazov A, Arondekar B, Lewis K, Rider A, Massey L, Lux MP.
- Cancers (Basel). 2022 Nov 2;14(21):5399. doi: 10.3390/cancers14215399.
-
- Clinical application of artificial neural network (ANN) modeling to predict BRCA1/2 germline deleterious variants in Chinese bilateral primary breast cancer patients.
- Li Y, Chen L, Lv J, Chen X, Zeng B, Chen M, Guo W, Lin Y, Yu L, Hou J, Li J, Zhou P, Zhang W, Li S, Jin X, Cai W, Zhang K, Huang Y, Wang C, Fu F.
- BMC Cancer. 2022 Nov 2;22(1):1125. doi: 10.1186/s12885-022-10160-y.
- PMID: 36324133
- PubMed abstract
-
- Breast cancer polygenic risk scores are associated with short-term risk of poor prognosis breast cancer.
- McCarthy AM, Manning AK, Hsu S, Welch M, Moy B, Lehman CD, Armstrong K.
- Breast Cancer Res Treat. 2022 Nov;196(2):389-398. doi: 10.1007/s10549-022-06739-5. Epub 2022 Sep 22.
- PMID: 36138293
- PubMed abstract
- Source abstract
-
- Aromatase inhibitors and contralateral breast cancer in BRCA mutation carriers.
- Nemati Shafaee M, Goutsouliak K, Lin H, Bevers TB, Gutierrez-Barrera A, Bondy M, Arun B.
- Breast Cancer Res Treat. 2022 Nov;196(1):143-152. doi: 10.1007/s10549-022-06688-z. Epub 2022 Aug 25.
- PMID: 36006499
- PubMed abstract
- Source abstract
-
- Real-World Study of Regional Differences in Patient Demographics, Clinical Characteristics, and BRCA1/2 Mutation Testing in Patients with Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer in the United States, Europe, and Israel.
- Mahtani R, Niyazov A, Lewis K, Rider A, Massey L, Arondekar B, Lux MP.
- Adv Ther. 2022 Oct 28. doi: 10.1007/s12325-022-02302-2. Epub ahead of print.
- PMID: 36333567
- PubMed abstract
-
- Interdisciplinary risk counseling for hereditary breast and ovarian cancer: real-world data from a specialized center.
- Zang B, Helms M, Besch L, Kalmbach N, Stegen S, Blohmer JU, Speiser D.
- Arch Gynecol Obstet. 2022 Oct 28. doi: 10.1007/s00404-022-06819-3. Epub ahead of print.
- PMID: 36307613
- PubMed abstract
-
- Ductal Carcinoma In Situ (DCIS) Diagnosed by MRI-Guided Biopsy among BRCA1/BRCA2 Mutation Carriers.
- Faermann R, Friedman E, Kaidar-Person O, Weidenfeld J, Brodsky M, Shalmon A, Neiman OH, Gotlieb M, Yagil Y, Samoocha D, Madorsky Feldman D, Sklair-Levy M.
- Breast J. 2022 Oct 27. doi: 10.1155/2022/4317693. Online ahead of print.
-
- PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients.
- Giardiello D, Hooning MJ, Hauptmann M, Keeman R, Heemskerk-Gerritsen BAM, Becher H, Blomqvist C, Bojesen SE, Bolla MK, Camp NJ, Czene K, Devilee P, Eccles DM, Fasching PA, Figueroa JD, Flyger H, García-Closas M, Haiman CA, Hamann U, Hopper JL, Jakubowska A, Leeuwen FE, Lindblom A, Lubinski J, Margolin S, Martinez ME, Nevanlinna H, Nevelsteen I, Pelders S, Pharoah PDP, Siesling S, Southey MC, van der Hout AH, van Hest LP, Chang-Claude J, Hall P, Easton DF, Steyerberg EW, Schmidt MK.
- Breast Cancer Res. 2022 Oct 21;24(1):69. doi: 10.1186/s13058-022-01567-3.
- PMID: 36271417
- PubMed abstract
-
- Genodermatoses – Opportunities for Early Detection and Cancer Prevention.
- Carley H, Kulkarni A.
- Curr Genet Med Rep. 2022 [2022 Oct 4];10(1):1-13. doi: 10.1007/s40142-022-00203-y. Epub 2022 Oct 4.
- PMID: 36213090
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Comparison of Clinical, Pathological, and Prognostic Features in BRCA Mutant and Wild-Type Male Breast Cancer Patients.
- Dogan I, Aydin E, Yazici H, Saip P.
- Eur J Breast Health. 2022 Oct 1;18(4):323-328. doi: 10.4274/ejbh.galenos.2022.2022-5-2.
- PMID: 36248747
- PubMed abstract
-
- Incidence of Occult Breast Cancer in Carriers of BRCA1/2 or Other High-Penetrance Pathogenic Variants Undergoing Prophylactic Mastectomy: When is Sentinel Lymph Node Biopsy Indicated?
- Wong SM, Ferroum A, Apostolova C, Alhassan B, Prakash I, Basik M, Boileau JF, Meterissian S, Aleynikova O, Wong N, Foulkes WD.
- Ann Surg Oncol. 2022 Oct;29(11):6660-6668. doi: 10.1245/s10434-022-11916-3. Epub 2022 May 26.
- PMID: 35616744
- PubMed abstract
- Source abstract
-
- Prognostic significance of germline BRCA mutations in patients with HER2-POSITIVE breast cancer.
- Viansone A, Pellegrino B, Omarini C, Pistelli M, Boggiani D, Sikokis A, Uliana V, Zanoni D, Tommasi C, Bortesi B, Bonatti F, Piacentini F, Cortesi L, Camisa R, Sgargi P, Michiara M, Musolino A.
- Breast. 2022 Oct;65:145-150. doi: 10.1016/j.breast.2022.07.012. Epub 2022 Jul 31.
- PMID: 35970028
- PubMed abstract
-
- Prevalence of BRCA1 and BRCA2 pathogenic variants in 8627 unselected patients with breast cancer: stratification of age at diagnosis, family history and molecular subtype.
- Zang F, Ding X, Chen J, Hu L, Sun J, Zhang J, Xu Y, Yao L, Xie Y.
- Breast Cancer Res Treat. 2022 Oct;195(3):431-439. doi: 10.1007/s10549-022-06702-4. Epub 2022 Aug 16.
- PMID: 35974241
- PubMed abstract
- Source abstract
-
- Contribution of BRCA1 5382insC mutation to triplene-gative and luminal types of breast cancer in Ukraine.
- Samusieva A, Serga S, Klymenko S, Rybchenko L, Klimuk B, Zakhartseva L, Gorovenko N, Lobanova O, Rossokha Z, Fishchuk L, Levkovich N, Medvedieva N, Popova O, Cheshuk V, Inomistova M, Khranovska N, Skachkova O, Michailovich Y, Ponomarova O, Kozeretska I.
- Breast Cancer Res Treat. 2022 Oct;195(3):453-459. doi: 10.1007/s10549-022-06692-3. Epub 2022 Aug 5.
- PMID: 35930098
- PubMed abstract
- Source abstract
-
- Intrathecal Methotrexate Toxicity Resulting in Brain Death due to Generalized Cerebral Edema Case Report.
- Pang H, Chan JL, Bannykh SI, Gezalian M, Lahiri S, Toossi S, Ayodele M.
- Neurohospitalist. 2022 Oct;12(4):697-701. doi: 10.1177/19418744221106313. Epub 2022 Jun 6.
- PMID: 36147762
- PubMed abstract
- Source abstract
-
- Multiple Bayesian network meta-analyses to establish therapeutic algorithms for metastatic triple negative breast cancer.
- Schettini F, Venturini S, Giuliano M, Lambertini M, Pinato DJ, Onesti CE, De Placido P, Harbeck N, Lüftner D, Denys H, Van Dam P, Arpino G, Zaman K, Mustacchi G, Gligorov J, Awada A, Campone M, Wildiers H, Gennari A, Tjan-Heijnen V, Bartsch R, Cortes J, Paris I, Martín M, De Placido S, Del Mastro L, Jerusalem G, Curigliano G, Prat A, Generali D.
- Cancer Treat Rev. 2022 Sep 28;111:102468. doi: 10.1016/j.ctrv.2022.102468. Epub ahead of print.
- PMID: 36202026
- PubMed abstract
- Review
- Free Full Text
-
- Frequent cleft lip and palate in families with pathogenic germline CDH1 variants.
- Green BL, Fasaye GA, Samaranayake SG, Duemler A, Gamble LA, Davis JL.
- Front Genet. 2022 Sep 28;13:1012025. doi: 10.3389/fgene.2022.1012025.
- PMID: 36246616
- PubMed abstract
-
- Alterations in Homologous Recombination-Related Genes and Distinct Platinum Response in Metastatic Triple-Negative Breast Cancers: A Subgroup Analysis of the ProfiLER-01 Trial.
- Bonnet E, Haddad V, Quesada S, Baffert KA, Lardy-Cléaud A, Treilleux I, Pissaloux D, Attignon V, Wang Q, Buisson A, Heudel PE, Bachelot T, Dufresne A, Eberst L, Toussaint P, Bonadona V, Lasset C, Viari A, Sohier E, Paindavoine S, Combaret V, Pérol D, Ray-Coquard I, Blay JY, Trédan O.
- J Pers Med. 2022 Sep 27;12(10):1595. doi: 10.3390/jpm12101595.
-
- Survival outcomes of metastatic breast cancer patients by germline BRCA1/2 status in a large multicenter real-world database.
- Mailliez A, D'Hondt V, Lusque A, Caron O, Cabel L, Goncalves A, Debled M, Gladieff L, Ferrero JM, Petit T, Mouret-Reynier MA, Eymard JC, Levy C, Uwer L, Leheurteur M, Desmoulins I, Bachelot T, Frenel ES, De la Motte Rouge T, Simon G, Jacot W, Delaloge S.
- Int J Cancer. 2022 Sep 26. doi: 10.1002/ijc.34304. Epub ahead of print.
- PMID: 36161271
- PubMed abstract
- Source abstract
-
- Germline Variants in 32 Cancer-Related Genes among 700 Chinese Breast Cancer Patients by Next-Generation Sequencing: A Clinic-Based, Observational Study.
- Yang L, Xie F, Liu C, Zhao J, Hu T, Wu J, Zhao X, Wang S.
- Int J Mol Sci. 2022 Sep 24;23(19):11266. doi: 10.3390/ijms231911266.
- PMID: 36232564
- PubMed abstract
- Source abstract
-
- Targeted Sequencing of Germline Breast Cancer Susceptibility Genes for Discovering Pathogenic/Likely Pathogenic Variants in the Jakarta Population.
- Panigoro SS, Paramita RI, Siswiandari KM, Fadilah F.
- Diagnostics (Basel). 2022 Sep 16;12(9):2241. doi: 10.3390/diagnostics12092241.
- PMID: 36140642
- PubMed abstract
- Source abstract
-
- Características clínicas de pacientes con Cáncer de Mama y / o Cáncer de Ovario con mutaciones en los genes BRCA1 y BRCA2 en Córdoba, Argentina. [Clinical characteristics of patients with Breast and / or Ovarian Cancer with mutations in the BRCA1 and BRCA2 genes in Córdoba, Argentina.]
- Martin CA, Suárez Villasmil L, Sembaj A, Gomez Balangione F, Zunino S, Montes CDC, Borello A, Del Castillo A, Zeballos M, Rossi NT.
- Rev Fac Cien Med Univ Nac Cordoba. 2022 Sep 16;79(3):228-234. Spanish. doi: 10.31053/1853.0605.v79.n3.34533.
- PMID: 36149077
- PubMed abstract
- Source abstract
- [Article in Spanish]
- Free Full Text
-
- Genetic and functional homologous repair deficiency as biomarkers for platinum sensitivity in TNBC: a case report.
- Gomez-Puerto D, Llop-Guevara A, Cruellas M, Torres-Esquius S, De La Torre J, Peg V, Balmaña J, Pimentel I.
- Front Oncol. 2022 Sep 14;12:963728. doi: 10.3389/fonc.2022.963728.
- PMID: 36185283
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- CDH1 (E-cadherin) Gene Methylation in Human Breast Cancer: Critical Appraisal of a Long and Twisted Story.
- Bücker L, Lehmann U.
- Cancers (Basel). 2022 Sep 8;14(18):4377. doi: 10.3390/cancers14184377.
- PMID: 36139537
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Constitutional BRCA1 Methylation and Risk of Incident Triple-Negative Breast Cancer and High-grade Serous Ovarian Cancer.
- Lønning PE, Nikolaienko O, Pan K, Kurian AW, Eikesdal HP, Pettinger M, Anderson GL, Prentice RL, Chlebowski RT, Knappskog S.
- JAMA Oncol. 2022 Sep 8. doi: 10.1001/jamaoncol.2022.3846. Epub ahead of print.
- PMID: 36074460
- PubMed abstract
-
- Constitutional Mosaicism: A Critical Issue in the Definition of BRCA-Inherited Cancer Risk.
- Tenedini E, Piana S, Toss A, Marino M, Barbieri E, Artuso L, Venturelli M, Gasparini E, Mandato VD, Marchi I, Castellano S, Luppi M, Trenti T, Cortesi L, Tagliafico E.
- JCO Precis Oncol. 2022 Aug [2022 Sep 8];6:e2200138. doi: 10.1200/PO.22.00138.
- PMID: 36075010
- PubMed abstract
- Source abstract
- Case report
- Free Full Text
-
- A progressive and refractory case of breast cancer with Cowden syndrome.
- Sueta A, Takeno M, Goto-Yamaguchi L, Tomiguchi M, Inao T, Yamamoto-Ibusuki M, Yamamoto Y.
- World J Surg Oncol. 2022 Sep 3;20(1):279. doi: 10.1186/s12957-022-02745-5.
- PMID: 36057718
- PubMed abstract
- Case report
- Free Full Text
-
- Breast cancer in a teenage girl with BRCA mutation: A case report from a low middle-income country.
- Vohra LM, Ali D, Hashmi SA, Angez M.
- Int J Surg Case Rep. 2022 Sep;98:107513. doi: 10.1016/j.ijscr.2022.107513. Epub 2022 Aug 13.
- PMID: 36027825
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- BRCA1, BRCA2, TP53, PIK3CA, PTEN and AKT1 genes mutations in Burkina Faso breast cancer patients: prevalence, spectrum and novel variant.
- Ouedraogo SY, Zoure AA, Zeye MMJ, Kiendrebeogo TI, Zhou X, Sawadogo AY, Simpore J, Chen H.
- Mol Genet Genomics. 2022 Sep;297(5):1257-1268. doi: 10.1007/s00438-022-01914-1. Epub 2022 Jun 22.
- PMID: 35731312
- PubMed abstract
- Source abstract
-
- Characterization of genetic predisposition to molecular subtypes of breast cancer in Brazilian patients.
- Paixão D, Torrezan GT, Santiago KM, Formiga MN, Ahuno ST, Dias-Neto E, Tojal da Silva I, Foulkes WD, Polak P, Carraro DM.
- Front Oncol. 2022 Aug 31;12:976959. doi: 10.3389/fonc.2022.976959.
- PMID: 36119527
- PubMed abstract
-
- Background Parenchymal Enhancement at Postoperative Surveillance Breast MRI: Association with Future Second Breast Cancer Risk.
- Lee SH, Jang MJ, Yoen H, Lee Y, Kim YS, Park AR, Ha SM, Kim SY, Chang JM, Cho N, Moon WK.
- Radiology. 2022 Aug 30:220440. doi: 10.1148/radiol.220440. Epub ahead of print.
- PMID: 36040335
- PubMed abstract
- Source abstract
Commentary:
Background Parenchymal Enhancement at Breast MRI: More Is Not Better.
- PMID: 36040339
- PubMed abstract
- Source abstract
-
- Eligibility, uptake and response to germline genetic testing in women with DCIS.
- Turza L, Lovejoy LA, Turner CE, Shriver CD, Ellsworth RE.
- Front Oncol. 2022 Aug 26;12:918757. doi: 10.3389/fonc.2022.918757.
- PMID: 36091166
- PubMed abstract
-
- Prevalence and Factors Associated with BRCA1/2 Gene Mutation in Chinese Populations with Breast Cancer.
- Huang G, Lu H, Chen Q, Huang X.
- Int J Gen Med. 2022 Aug 24;15:6783-6789. doi: 10.2147/IJGM.S378706.
- PMID: 36042935
- PubMed abstract
-
- Strong founder effect for BRCA1 c.3629_3630delAG pathogenic variant in Chechen patients with breast or ovarian cancer.
- Sokolenko AP, Sultanova LV, Stepanov IA, Romanko AA, Venina AR, Sokolova TN, Musayeva HS, Tovgereeva MY, Magomedova MK, Akhmatkhanov KU, Vagapova EI, Suleymanov EA, Vasilyeva EV, Bakaeva EK, Bizin IV, Aleksakhina SN, Imyanitov EN.
- Cancer Med. 2022 Aug 23. doi: 10.1002/cam4.5159. Epub ahead of print.
- PMID: 36000185
- PubMed abstract
- Source abstract
-
- BRCA1/2 variants and copy number alterations status in non familial triple negative breast cancer and high grade serous ovarian cancer.
- El Ansari FZ, Jouali F, Fekkak R, Bakkach J, Ghailani Nourouti N, Barakat A, Bennani Mechita M, Fekkak J.
- Hered Cancer Clin Pract. 2022 Aug 19;20(1):29. doi: 10.1186/s13053-022-00236-y.
- PMID: 35986351
- PubMed abstract
-
- Breast Cancer Risk in Women from Ghana Carrying Rare Germline Pathogenic Mutations.
- Ahearn TU, Choudhury PP, Derkach A, Wiafe-Addai B, Awuah B, Yarney J, Edusei L, Titiloye N, Adjei E, Vanderpuye V, Aitpillah F, Dedey F, Oppong J, Osei-Bonsu EB, Duggan MA, Brinton LA, Allen J, Luccarini C, Baynes C, Carvalho S, Dunning AM, Davis Lynn BC, Chanock SJ, Hicks BD, Yeager M, Chatterjee N, Biritwum R, Clegg-Lamptey JN, Nyarko K, Wiafe S, Ansong D, Easton DF, Figueroa JD, Garcia-Closas M.
- Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8):1593-1601. doi: 10.1158/1055-9965.EPI-21-1397.
- PMID: 35654374
- PubMed abstract
- Source abstract
-
- Association between Ancestry-Specific 6q25 Variants and Breast Cancer Subtypes in Peruvian Women.
- Zavala VA, Casavilca-Zambrano S, Navarro-Vásquez J, Castañeda CA, Valencia G, Morante Z, Calderón M, Abugattas JE, Gómez H, Fuentes HA, Liendo-Picoaga R, Cotrina JM, Monge C, Neciosup SP, Huntsman S, Hu D, Sánchez SE, Williams MA, Núñez-Marrero A, Godoy L, Hechmer A, Olshen AB, Dutil J, Ziv E, Zabaleta J, Gelaye B, Vásquez J, Gálvez-Nino M, Enriquez-Vera D, Vidaurre T, Fejerman L.
- Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8):1602-1609. doi: 10.1158/1055-9965.EPI-22-0069.
- PMID: 35654312
- PubMed abstract
- Source abstract
-
- Genetic and clinical characteristics of BRCA-associated hereditary breast cancer in the West region of Kazakhstan.
- Aitmagambetova MA, Smagulova GA, Tuhvatshin RR, Zheksenova AN, Amanzholkyzy A.
- Carcinogenesis. 2022 Aug 2:bgac068. doi: 10.1093/carcin/bgac068. Epub ahead of print.
- PMID: 35917581
- PubMed abstract
- Source abstract
-
- What are the considerations in patient selection and timing of risk-reducing mastectomy?
- Pederson HJ, Kurian AW, Al Hilli Z.
- Cleve Clin J Med. 2022 Aug 1;89(8):442-444. doi: 10.3949/ccjm.89a.21114.
- PMID: 35914935
- PubMed abstract
-
- Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
- Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C.
- Ann Oncol. 2022 Aug;33(8):769-785. doi: 10.1016/j.annonc.2022.05.006. Epub 2022 May 21.
- PMID: 35605746
- PubMed abstract
- Review
- Free Full Text
-
- Characterization of the HER2 status in BRCA-mutated breast cancer: a single institutional series and systematic review with pooled analysis.
- Tomasello G, Gambini D, Petrelli F, Azzollini J, Arcanà C, Ghidini M, Peissel B, Manoukian S, Garrone O.
- ESMO Open. 2022 Aug;7(4):100531. doi: 10.1016/j.esmoop.2022.100531. Epub 2022 Jul 8.
- PMID: 35810556
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Histological and Immunohistochemical Characteristics for Hereditary Breast Cancer Risk in a Cohort of Brazilian Women.
- de Freitas RM, Guerra MR, Fayer VA, Campos AAL, Cintra JRD, Warren J, Ervilha RR, de Paula CD, Bustamante-Teixeira MT.
- Rev Bras Ginecol Obstet. 2022 Aug;44(8):761-770. English. doi: 10.1055/s-0042-1743103. Epub 2022 Apr 25.
- PMID: 35468643
- PubMed abstract
- Source abstract
-
- Breast cancer in East Africa: Prevalence and spectrum of germline SNV/indel and CNVs in BRCA1 and BRCA2 genes among breast cancer patients in Tanzania.
- Rweyemamu LP, Gültaslar BK, Akan G, Dharsee N, Namkinga LA, Lyantagaye SL, Yazici H, Atalar F.
- Cancer Med. 2022 Jul 31. doi: 10.1002/cam4.5091. Epub ahead of print.
- PMID: 35908255
- PubMed abstract
- Source abstract
-
- Satisfaction and Quality of Life of Healthy and Unilateral Diseased BRCA1/2 Pathogenic Variant Carriers after Risk-Reducing Mastectomy and Reconstruction Using the BREAST-Q Questionnaire.
- Herold N, Hellmich M, Lichtenheldt F, Ataseven B, Hillebrand V, Wappenschmidt B, Schmutzler RK, Rhiem K.
- Genes (Basel). 2022 Jul 28;13(8):1357. doi: 10.3390/genes13081357.
- PMID: 36011268
- PubMed abstract
- Source abstract
-
- High grade acinic cell carcinoma of the breast with clear cytoplasm mimics clear cell carcinoma in a BRCA1 mutation carrier: a case report and review of the literature on the molecular analysis.
- Min L, Qiao H, Hongkai Z.
- Histol Histopathol. 2022 Jul 27:18501. doi: 10.14670/HH-18-501. Epub ahead of print.
- PMID: 35894298
- PubMed abstract
- Source abstract
- Case report
- Free Full Text (PDF)
-
- Management Strategies of Breast Cancer Patients with BRCA1 and BRCA2 Pathogenic Germline Variants.
- Edaily S, Abdel-Razeq H.
- Onco Targets Ther. 2022 Jul 27;15:815-826. doi: 10.2147/OTT.S369844.
- PMID: 35923470
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Germline Testing in a Cohort of Patients at High Risk of Hereditary Cancer Predisposition Syndromes: First Two-Year Results from South Italy.
- Paduano F, Colao E, Fabiani F, Rocca V, Dinatolo F, Dattola A, D'Antona L, Amato R, Trapasso F, Baudi F, Perrotti N, Iuliano R.
- Genes (Basel). 2022 Jul 21;13(7):1286. doi: 10.3390/genes13071286.
- PMID: 35886069
- PubMed abstract
- Source abstract
-
- Peutz-Jeghers Syndrome.
- Wu M, Krishnamurthy K.
- StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. 2022 Jul 19.
- PMID: 30570978
- PubMed abstract
- Review
- Free Full Text
-
- Study Confirms BRCA1 and BRCA2 Linked to Seven Cancers.
- Alexander W.
- Medscape Oncology. 2022 Jul 12.
- Research news
- Free Full Text
Original research:
Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants.
- PMID: 35420638
- PubMed abstract
- Free Full Text
-
- Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.
- Dumont M, Weber-Lassalle N, Joly-Beauparlant C, Ernst C, Droit A, Feng BJ, Dubois S, Collin-Deschesnes AC, Soucy P, Vallée M, Fournier F, Lemaçon A, Adank MA, Allen J, Altmüller J, Arnold N, Ausems MGEM, Berutti R, Bolla MK, Bull S, Carvalho S, Cornelissen S, Dufault MR, Dunning AM, Engel C, Gehrig A, Geurts-Giele WRR, Gieger C, Green J, Hackmann K, Helmy M, Hentschel J, Hogervorst FBL, Hollestelle A, Hooning MJ, Horváth J, Ikram MA, Kaulfuß S, Keeman R, Kuang D, Luccarini C, Maier W, Martens JWM, Niederacher D, Nürnberg P, Ott CE, Peters A, Pharoah PDP, Ramirez A, Ramser J, Riedel-Heller S, Schmidt G, Shah M, Scherer M, Stäbler A, Strom TM, Sutter C, Thiele H, van Asperen CJ, van der Kolk L, van der Luijt RB, Volk AE, Wagner M, Waisfisz Q, Wang Q, Wang-Gohrke S, Weber BHF, Genome Of The Netherlands Project, Ghs Study Group, Devilee P, Tavtigian S, Bader GD, Meindl A, Goldgar DE, Andrulis IL, Schmutzler RK, Easton DF, Schmidt MK, Hahnen E, Simard J.
- Cancers (Basel). 2022 Jul 11;14(14):3363. doi: 10.3390/cancers14143363.
- PMID: 35884425
- PubMed abstract
- Source abstract
-
- Impact of low versus negative estrogen/progesterone receptor status on clinico-pathologic characteristics and survival outcomes in HER2-negative breast cancer.
- Yoder R, Kimler BF, Staley JM, Schwensen K, Wang YY, Finke K, O'Dea A, Nye L, Elia M, Crane G, McKittrick R, Pluenneke R, Madhusudhana S, Beck L, Shrestha A, Corum L, Marsico M, Stecklein SR, Godwin AK, Khan QJ, Sharma P.
- NPJ Breast Cancer. 2022 Jul 11;8(1):80. doi: 10.1038/s41523-022-00448-4.
- PMID: 35817765
- PubMed abstract
-
- Prevalence of Cancer Predisposition Germline Variants in Male Breast Cancer Patients: Results of the German Consortium for Hereditary Breast and Ovarian Cancer.
- Rolfes M, Borde J, Möllenhoff K, Kayali M, Ernst C, Gehrig A, Sutter C, Ramser J, Niederacher D, Horváth J, Arnold N, Meindl A, Auber B, Rump A, Wang-Gohrke S, Ritter J, Hentschel J, Thiele H, Altmüller J, Nürnberg P, Rhiem K, Engel C, Wappenschmidt B, Schmutzler RK, Hahnen E, Hauke J.
- Cancers (Basel). 2022 Jul 5;14(13):3292. doi: 10.3390/cancers14133292.
- PMID: 35805063
- PubMed abstract
- Source abstract
-
- Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management.
- Yoshimura A, Imoto I, Iwata H.
- Int J Mol Sci. 2022 Jul 5;23(13):7481. doi: 10.3390/ijms23137481.
- PMID: 35806485
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Predominance of BRCA2 Mutation and Estrogen Receptor Positivity in Unselected Breast Cancer with BRCA1 or BRCA2 Mutation.
- Pujol P, Yauy K, Coffy A, Duforet-Frebourg N, Gabteni S, Daurès JP, Penault Llorca F, Thomas F, Hughes K, Turnbull C, Galibert V, Rideau C, Corsini C, Collet L, You B, Geneviève D, Philippe N.
- Cancers (Basel). 2022 Jul 4;14(13):3266. doi: 10.3390/cancers14133266.
- PMID: 35805038
- PubMed abstract
- Source abstract
- Meta-Analysis
- Free PMC article
- Free Full Text
-
- Adherence to the 2020 American Cancer Society Guideline for Cancer Prevention and risk of breast cancer for women at increased familial and genetic risk in the Breast Cancer Family Registry: an evaluation of the weight, physical activity, and alcohol consumption recommendations.
- Geczik AM, Ferris JS, Terry MB, Andrulis IL, Buys SS, Daly MB, Hopper JL, John EM, Kurian AW, Southey MC, Liao Y, Genkinger JM.
- Breast Cancer Res Treat. 2022 Jul 2. doi: 10.1007/s10549-022-06656-7. Epub ahead of print.
- PMID: 35780210
- PubMed abstract
- Source abstract
-
- Characteristics of breast cancer patients tested for germline BRCA1/2 mutations by next-generation sequencing in Ramathibodi Hospital, Mahidol University.
- Oranratnachai S, Yamkaew W, Tunteeratum A, Sukarayothin T, Iemwimangsa N, Panvichien R.
- Cancer Rep (Hoboken). 2022 Jul 1:e1664. doi: 10.1002/cnr2.1664. Epub ahead of print.
- PMID: 35778884
- PubMed abstract
- Source abstract
-
- PALB2 germline mutations in a multi-gene panel testing cohort of 1905 breast-ovarian cancer patients in Argentina.
- Gonzalez A, Del Greco F, Vargas-Roig L, Brun B, Tabares G, Mampel A, Montes C, Martin C, Lopez M, Rossi N, Bruno L, Ponce C, Quaglio P, Yanzi A, Acevedo S, Lugo L, Lopez Breccia P, Avila S, Sisterna S, Del Castillo MS, Vazquez M, Nuñez LM.
- Breast Cancer Res Treat. 2022 Jul;194(2):403-412. doi: 10.1007/s10549-022-06620-5. Epub 2022 May 24.
- PMID: 35610400
- PubMed abstract
- Source abstract
-
- Survival of BRCA1/BRCA2-associated pT1 breast cancer patients, a cohort study.
- van Barele M, Rieborn A, Heemskerk-Gerritsen BAM, Obdeijn IM, Koppert LB, Loo CE, Tollenaar RAEM, Ausems MGEM, van de Beek I, Berger LPV, de Boer M, van Hest LP, Kets CM, Rookus M; Hebon, Schmidt MK, Jager A, Hooning MJ.
- Breast Cancer Res Treat. 2022 Jul;194(1):159-170. doi: 10.1007/s10549-022-06608-1. Epub 2022 May 4.
- PMID: 35507134
- PubMed abstract
-
- Clinicopathological Characterization of Double Heterozygosity for BRCA1 and BRCA2 Variants in Korean Breast Cancer Patients.
- Bang YJ, Kwon WK, Nam SJ, Kim SW, Chae BJ, Lee SK, Ryu JM, Kim JW, Yu J, Lee JE.
- Cancer Res Treat. 2022 Jul;54(3):827-833. doi: 10.4143/crt.2021.791. Epub 2021 Oct 13.
- PMID: 34645131
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Durable Disease-free Survival in a Patient with Metastatic Triple-negative Breast Cancer Treated with Olaparib Monotherapy.
- Wang X, Hu N, Cui L, Si Y, Yue J, Zheng F, Kang Y, Yuan P.
- Curr Cancer Drug Targets. 2022 [Jul];22(6):530-536. doi: 10.2174/1568009622666220214092207.
- PMID: 35156571
- PubMed abstract
- Source abstract
- Case report
- Free Full Text
-
- Evaluating breast cancer predisposition genes in women of African ancestry.
- Díaz-Zabala H, Guo X, Ping J, Wen W, Shu XO, Long J, Lipworth L, Li B, Fadden MK, Pal T, Blot WJ, Cai Q, Haiman CA, Palmer JR, Sanderson M, Zheng W.
- Genet Med. 2022 Jul;24(7):1468-1475. doi: 10.1016/j.gim.2022.03.015. Epub 2022 Apr 8.
- PMID: 35396981
- PubMed abstract
- Source abstract
-
- Founder BRCA1 mutations in Nepalese population.
- Mehta A, Diwan H, Gupta G, Nathany S, Agnihotri S, Dhanda S.
- J Pathol Transl Med. 2022 Jul;56(4):212-216. doi: 10.4132/jptm.2022.05.02. Epub 2022 Jun 15.
- PMID: 35698740
- PubMed abstract
-
- Germline mutations in Chinese ovarian cancer with or without breast cancer.
- Kwong A, Ho CYS, Shin VY, Au CH, Luk WP, Fung LH, Chan TL, Chan KKL, Ngan HYS, Ma ESK.
- Mol Genet Genomic Med. 2022 Jul;10(7):e1940. doi: 10.1002/mgg3.1940. Epub 2022 May 24.
- PMID: 35608067
- PubMed abstract
- Source abstract
-
- Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers.
- Borde J, Laitman Y, Blümcke B, Niederacher D, Weber-Lassalle K, Sutter C, Rump A, Arnold N, Wang-Gohrke S, Horváth J, Gehrig A, Schmidt G, Dutrannoy V, Ramser J, Hentschel J, Meindl A, Schroeder C, Wappenschmidt B, Engel C, Kuchenbaecker K, Schmutzler RK, Friedman E, Hahnen E, Ernst C.
- BMC Cancer. 2022 Jun 27;22(1):706. doi: 10.1186/s12885-022-09780-1.
- PMID: 35761208
- PubMed abstract
-
- Breast Cancer with Low Recurrence Score on Oncotype DX©: Interplay Between Early Recurrence, Lobular Histology and BRCA Mutation.
- Zarbiv Y, Wygoda YB, Grinshpun A, Hamburger T, Sella T, Breuer S, Maimon O, Rottenberg Y, Peretz T, Kadouri L.
- Oncol Ther. 2022 Jun 25. doi: 10.1007/s40487-022-00202-7. Epub ahead of print.
- PMID: 35751801
- PubMed abstract
-
- Genomic Breakpoints’ Characterization of a Large CHEK2 Duplication in an Italian Family with Hereditary Breast Cancer.
- Germani A, Guadagnolo D, Salvati V, Micolonghi C, Mancini R, Mastromoro G, Sadeghi S, Petrucci S, Pizzuti A, Piane M.
- Diagnostics (Basel). 2022 Jun 22;12(7):1520. doi: 10.3390/diagnostics12071520.
- PMID: 35885426
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Spectrum of germline pathogenic variants using a targeted next generation sequencing panel and genotype-phenotype correlations in patients with suspected hereditary breast cancer at an academic medical centre in Pakistan.
- Akbar F, Siddiqui Z, Waheed MT, Ehsan L, Ali SI, Wiquar H, Valimohammed AT, Khan S, Vohra L, Zeeshan S, Rashid Y, Moosajee M, Jabbar AA, Zahir MN, Zahid N, Soomro R, Ullah NN, Ahmad I, Haider G, Ansari U, Rizvi A, Mehboobali A, Sattar A, Kirmani S.
- Hered Cancer Clin Pract. 2022 Jun 16;20(1):24. doi: 10.1186/s13053-022-00232-2.
- PMID: 35710434
- PubMed abstract
-
- The mutation landscape of multiple cancer predisposition genes in Chinese familial/hereditary breast cancer families.
- Dong L, Zhang H, Zhang H, Ye Y, Cheng Y, Li L, Wei L, Han L, Cao Y, Li S, Hao X, Liu J, Yu J.
- Cancer Biol Med. 2021 Sep 28 [2022 Jun 15];19(6):850–70. doi: 10.20892/j.issn.2095-3941.2021.0011. Epub ahead of print.
- PMID: 34570441
- PubMed abstract
-
- Common Multiple Primary Cancers Associated With Breast and Gynecologic Cancers and Their Risk Factors, Pathogenesis, Treatment and Prognosis: A Review.
- Ge S, Wang B, Wang Z, He J, Ma X.
- Front Oncol. 2022 Jun 8;12:840431. doi: 10.3389/fonc.2022.840431.
- PMID: 35756608
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Are Mutation Carrier Patients Different from Non-Carrier Patients? Genetic, Pathology, and US Features of Patients with Breast Cancer.
- Pintican RM, Chiorean A, Duma M, Feier D, Szep M, Eniu D, Goidescu I, Dudea S.
- Cancers (Basel). 2022 Jun 2;14(11):2759. doi: 10.3390/cancers14112759.
- PMID: 35681739
- PubMed abstract
- Source abstract
-
- Genetic Aspects of Mammographic Density Measures Associated with Breast Cancer Risk.
- Li S, Nguyen TL, Nguyen-Dumont T, Dowty JG, Dite GS, Ye Z, Trinh HN, Evans CF, Tan M, Sung J, Jenkins MA, Giles GG, Hopper JL, Southey MC.
- Cancers (Basel). 2022 Jun 2;14(11):2767. doi: 10.3390/cancers14112767.
- PMID: 35681745
- PubMed abstract
- Source abstract
-
- The yield and effectiveness of breast cancer surveillance in women with PTEN Hamartoma Tumor Syndrome.
- Hoxhaj A, Drissen MMCM, Vos JR, Bult P, Mann RM, Hoogerbrugge N.
- Cancer. 2022 Jun 1. doi: 10.1002/cncr.34326. Epub ahead of print
-
- Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer.
- Waks AG, Kim D, Jain E, Snow C, Kirkner GJ, Rosenberg SM, Oh C, Poorvu PD, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Brachtel EF, Warner E, Collins LC, Partridge AH, Wagle N.
- Clin Cancer Res. 2022 Jun 1;28(11):2339-2348. doi: 10.1158/1078-0432.CCR-21-2572.
- PMID: 35101884
- PubMed abstract
Commentary:
One Size Does Not Fit All: Breast Cancer in Young Women.
- PMID: 35320364
- PubMed abstract
- Source abstract
-
- Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants.
- Momozawa Y, Sasai R, Usui Y, Shiraishi K, Iwasaki Y, Taniyama Y, Parsons MT, Mizukami K, Sekine Y, Hirata M, Kamatani Y, Endo M, Inai C, Takata S, Ito H, Kohno T, Matsuda K, Nakamura S, Sugano K, Yoshida T, Nakagawa H, Matsuo K, Murakami Y, Spurdle AB, Kubo M.
- JAMA Oncol. 2022 Jun 1;8(6):871-878. doi: 10.1001/jamaoncol.2022.0476.
- PMID: 35420638
- PubMed abstract
Research news: Study Confirms BRCA1 and BRCA2 Linked to Seven Cancers. (Medscape Oncology)
-
- The Effect of Age on Outcomes After Neoadjuvant Chemotherapy for Breast Cancer.
- Verdial FC, Mamtani A, Pawloski KR, Sevilimedu V, D'Alfonso TM, Zhang H, Gemignani ML, Barrio AV, Morrow M, Tadros AB.
- Ann Surg Oncol. 2022 Jun;29(6):3810-3819. doi: 10.1245/s10434-022-11367-w. Epub 2022 Mar 5.
- PMID: 35246810
- PubMed abstract
- Source abstract
-
- Outcomes of non-metastatic triple negative breast cancers: Real-world data from a large Indian cohort.
- Bajpai J, Kashyap L, Vallathol DH, Das A, Singh M, Pathak R, Rath S, Sekar A, Mohanta S, Reddy A, Joshi S, Nandhana R, Ravind R, Wadasadawala T, Nair N, Ghosh J, Parmar V, Gulia S, Desai S, Shet T, Thakur M, Patil A, Sarin R, Gupta S, Badwe R.
- Breast. 2022 Jun;63:77-84. doi: 10.1016/j.breast.2022.03.011. Epub 2022 Mar 19.
- PMID: 35334242
- PubMed abstract
-
- PTEN alterations in sporadic and BRCA1-associated triple negative breast carcinomas.
- Jones N, Gros A, Velasco V, Dapremont V, Brouste V, Gastaldello B, Debled M, Tunon de Lara C, Bonnet F, Barouk-Simonet E, Bubien V, Venat L, MacGrogan G, Longy M, Sevenet N.
- Cancer Genet. 2022 Jun;264-265:8-15. doi: 10.1016/j.cancergen.2022.02.008. Epub 2022 Feb 25.
- PMID: 35263698
- PubMed abstract
- Source abstract
-
- Case Report: Male Lobular Breast Cancer in Hereditary Cancer Syndromes.
- Carnevali I, Tedaldi G, Pensotti V, Sahnane N, Micello D, Rovera F, Sessa F, Tibiletti MG.
- Front Oncol. 2022 May 24;12:891426. doi: 10.3389/fonc.2022.891426.
- PMID: 35686104
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Truncating TINF2 p.Tyr312Ter variant and inherited breast cancer susceptibility.
- Koivuluoma S, Vorimo S, Mattila TM, Tervasmäki A, Kumpula T, Kuismin O, Winqvist R, Moilanen J, Mantere T, Pylkäs K.
- Fam Cancer. 2022 May 20. doi: 10.1007/s10689-022-00295-z. Epub ahead of print.
- PMID: 35590014
- PubMed abstract
-
- Apparent regional differences in the spectrum of BARD1 pathogenic variants in Spanish population and importance of copy number variants.
- Benito-Sánchez B, Barroso A, Fernández V, Mercadillo F, Núñez-Torres R, Pita G, Pombo L, Morales-Chamorro R, Cano-Cano JM, Urioste M, González-Neira A, Osorio A.
- Sci Rep. 2022 May 20;12(1):8547. doi: 10.1038/s41598-022-12480-2.
- PMID: 35595798
- PubMed abstract
-
- Therapeutic pattern and progress of neoadjuvant treatment for triple-negative breast cancer.
- Xiao Y, Gao W.
- Oncol Lett. 2022 May 19;24(1):219. doi: 10.3892/ol.2022.13340.
- PMID: 35720488
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Molecular phenotypes and clinical characterization of familial hereditary breast cancer among half and full sisters.
- Xu Y, He J, Qian C, Yang C.
- BMC Womens Health. 2022 May 2;22(1):145. doi: 10.1186/s12905-022-01732-y.
- PMID: 35501747
- PubMed abstract
-
- CDH1 germline mutations in families with hereditary lobular breast cancer.
- Girardi A, Magnoni F, Vicini E, Kouloura A, La Vecchia C, Veronesi P, Corso G.
- Eur J Cancer Prev. 2022 May 1;31(3):274-278. doi: 10.1097/CEJ.0000000000000688.
- PMID: 33990097
- PubMed abstract
- Source abstract
-
- Real-world clinical outcomes of patients with BRCA-mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: a CancerLinQ® study.
- Miller RS, Mokiou S, Taylor A, Sun P, Baria K.
- Breast Cancer Res Treat. 2022 May;193(1):83-94. doi: 10.1007/s10549-022-06541-3. Epub 2022 Feb 22.
- PMID: 35194731
- PubMed abstract
-
- Common founder BRCA2 pathogenic variants and breast cancer characteristics in Ethiopian Jews.
- Lieberman S, Chen-Shtoyerman R, Levi Z, Shkedi-Rafid S, Zuckerman S, Bernstein-Molho R, Levi GR, Shachar SS, Flugelman A, Libman V, Kedar I, Naftaly-Nathan S, Lagovsky I, Peretz T, Karminsky N, Carmi S, Levy-Lahad E, Goldberg Y.
- Breast Cancer Res Treat. 2022 May;193(1):217-224. doi: 10.1007/s10549-022-06557-9. Epub 2022 Mar 12.
- PMID: 35278150
- PubMed abstract
- Source abstract
-
- Identification of hereditary breast and ovarian cancer germline variants in Granada (Spain): NGS perspective.
- Molina-Zayas M, Garrido-Navas C, García-Puche JL, Barwell J, Pedrinaci S, Atienza MM, García-Linares S, de Haro-Muñoz T, Lorente JA, Serrano MJ, Poyatos-Andújar A.
- Mol Genet Genomics. 2022 May;297(3):859-871. doi: 10.1007/s00438-022-01891-5. Epub 2022 Apr 22.
- PMID: 35451682
- PubMed abstract
-
- Genetic, clinic and histopathologic characterization of BRCA-associated hereditary breast and ovarian cancer in southwestern Finland.
- Pallonen TA, Lempiäinen SMM, Joutsiniemi TK, Aaltonen RI, Pohjola PE, Kankuri-Tammilehto MK.
- Sci Rep. 2022 Apr 25;12(1):6704. doi: 10.1038/s41598-022-10519-y.
- PMID: 35469032
- PubMed abstract
-
- Choroidal Metastasis With Secondary Retinal Detachment in a Man With BCRA2-Associated Breast Adenocarcinoma.
- Sanayei N, Davoudi S, Port A, Chen X.
- Cureus. 2022 Apr 18;14(4):e24243. doi: 10.7759/cureus.24243.
- PMID: 35602814
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Male Breast Cancer: From Molecular Genetics to Clinical Management.
- Pensabene M, Von Arx C, De Laurentiis M.
- Cancers (Basel). 2022 Apr 15;14(8):2006. doi: 10.3390/cancers14082006.
- PMID: 35454911
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- A South African Indian population group dataset for breast cancer and BRCA1/2 variants.
- Combrink HMVE, van der Merwe NC, Katarya R, de Wet K, Motloung MH.
- Data Brief. 2022 Apr 14;42:108180. doi: 10.1016/j.dib.2022.108180.
- PMID: 35496481
- PubMed abstract
Original research:
Mutations in BRCA-related breast and ovarian cancer in the South African Indian population: A descriptive study.
- PMID: 34218100
- PubMed abstract
- Source abstract
-
- Germline Mutational Landscape in Chinese Patients With Advanced Breast Cancer.
- Zhang J, Wang N, Zheng T, Lu T, Zhang R, Ran R, Li K, Huang Y, Xie F, Zhang Y, Jia S, Yu J, Li H.
- Front Oncol. 2022 Apr 13;12:745796. doi: 10.3389/fonc.2022.745796.
- PMID: 35494038
- PubMed abstract
-
- Phylogenetic Analysis IDs Subset of De Novo Tumors Unrelated to Primary DCIS.
- Ray T.
- GenomeWeb. Disease Areas. Cancer. 2022 Apr 11.
- Conference report
- Source abstract
-
- Some Recurrent DCIS Breast Tumors are Actually New Lesions.
- [No author given]
- Inside Precision Medicine. Topics. Oncology. 2022 Apr 11.
- Conference report
- Free Full Text
-
- Incidence and impact of brain metastasis in patients with hereditary BRCA1 or BRCA2 mutated invasive breast cancer.
- Garber HR, Raghavendra AS, Lehner M, Qiao W, Gutierrez-Barrera AM, Tripathy D, Arun B, Ibrahim NK.
- NPJ Breast Cancer. 2022 Apr 7;8(1):46. doi: 10.1038/s41523-022-00407-z.
- PMID: 35393462
- PubMed abstract
-
- Mutational Analysis of BRCA1 and BRCA2 Genes in Breast Cancer Patients from Eastern Sicily.
- Stella S, Vitale SR, Martorana F, Massimino M, Pavone G, Lanzafame K, Bianca S, Barone C, Gorgone C, Fichera M, Manzella L.
- Cancer Manag Res. 2022 Apr 5;14:1341-1352. doi: 10.2147/CMAR.S348529.
- PMID: 35411189
- PubMed abstract
-
- Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors.
- Disciglio V, Sanese P, Fasano C, Lotesoriere C, Valentini AM, Forte G, Lepore Signorile M, De Marco K, Grossi V, Lolli I, Cariola F, Simone C.
- Genes (Basel). 2022 Apr 5;13(4):644. doi: 10.3390/genes13040644.
- PMID: 35456450
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Spectrum of BRCA1/2 Mutations in Romanian Breast and Ovarian Cancer Patients.
- Vidra R, Ciuleanu TE, Nemes A, Pascu O, Heroiu AM, Antone N, Vidrean AI, Oprean CM, Pop LA, Berindan-Neagoe I, Eniu R, Eniu A.
- Int J Environ Res Public Health. 2022 Apr 4;19(7):4314. doi: 10.3390/ijerph19074314.
- PMID: 35409996
- PubMed abstract
- Source abstract
-
- Exploratory analysis of biomarkers associated with clinical outcomes from the study of palbociclib plus endocrine therapy in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer.
- Lee S, Park K, Kim GM, Jung KH, Kang SY, Park IH, Kim JH, Ahn HK, Park WY, Im SA, Park YH.
- Breast. 2022 Apr;62:52-60. doi: 10.1016/j.breast.2022.01.014. Epub 2022 Jan 29.
- PMID: 35124320
- PubMed abstract
-
- Impact of BRCA mutation on the survival and risk of contralateral breast cancer in Asian breast cancer patients.
- Lin PH, Chen SC, Tseng LM, Chang KJ, Huang AC, Cheng KC, Yang K, Wu HC, Chao TY, Chang YC, Lin PC, Kuo WH, Kuo WL, Lin CH, Chen HM, Yeh DC, Liu LC, Liu CY, Wang MY, Lo C, Lu YS, Huang CS.
- Breast Cancer Res Treat. 2022 Apr;192(3):629-637. doi: 10.1007/s10549-021-06446-7. Epub 2022 Feb 3.
- PMID: 35113257
- PubMed abstract
- Source abstract
-
- Somatic loss of the remaining allele occurs approximately in half of CHEK2-driven breast cancers and is accompanied by a border-line increase of chromosomal instability.
- Iyevleva AG, Aleksakhina SN, Sokolenko AP, Baskina SV, Venina AR, Anisimova EI, Bizin IV, Ivantsov AO, Belysheva YV, Chernyakova AP, Togo AV, Imyanitov EN.
- Breast Cancer Res Treat. 2022 Apr;192(2):283-291. doi: 10.1007/s10549-022-06517-3. Epub 2022 Jan 12.
- PMID: 35020107
- PubMed abstract
- Source abstract
-
- Comparison of mutational profiles between triple-negative and hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancers in T2N0-1M0 stage: Implications of TP53 and PIK3CA mutations in Korean early-stage breast cancers.
- Lee S, Kim HY, Jung YJ, Jung CS, Im D, Kim JY, Lee SM, Oh SH.
- Curr Probl Cancer. 2022 Apr;46(2):100843. doi: 10.1016/j.currproblcancer.2022.100843. Epub 2022 Feb 9.
- PMID: 35180531
- PubMed abstract
-
- Extended gene panel testing in lobular breast cancer.
- van Veen EM, Evans DG, Harkness EF, Byers HJ, Ellingford JM, Woodward ER, Bowers NL, Wallace AJ, Howell SJ, Howell A, Lalloo F, Newman WG, Smith MJ.
- Fam Cancer. 2022 Apr;21(2):129-136. doi: 10.1007/s10689-021-00241-5. Epub 2021 Mar 25.
- PMID: 33763779
- PubMed abstract
-
- First international workshop of the ATM and cancer risk group (4-5 December 2019).
- Lesueur F, Easton DF, Renault AL, Tavtigian SV, Bernstein JL, Kote-Jarai Z, Eeles RA, Plaseska-Karanfia D, Feliubadaló L; Spanish ATM working group, Arun B, Herold N, Versmold B, Schmutzler RK; GC-HBOC, Nguyen-Dumont T, Southey MC, Dorling L, Dunning AM, Ghiorzo P, Dalmasso BS, Cavaciuti E, Le Gal D, Roberts NJ, Dominguez-Valentin M, Rookus M, Taylor AMR, Goldstein AM, Goldgar DE; CARRIERS and Ambry Groups, Stoppa-Lyonnet D, Andrieu N.
- Fam Cancer. 2022 Apr;21(2):211-227. doi: 10.1007/s10689-021-00248-y. Epub 2021 Jun 14.
- PMID: 34125377
- PubMed abstract
- Source abstract
-
- CDH1 pathogenic variants and cancer risk in an unselected patient population.
- Bar-Mashiah A, Soper ER, Cullina S, Belbin GM, Kenny EE, Lucas AL, Abul-Husn NS.
- Fam Cancer. 2022 Apr;21(2):235-239. doi: 10.1007/s10689-021-00257-x. Epub 2021 Apr 22.
- PMID: 33886068
- PubMed abstract
- Source abstract
-
- Cancer risk and genotype-phenotype correlation in Japanese patients with Cowden syndrome.
- Teramae S, Muguruma N, Okamoto K, Oseto K, Nishikawa R, Tanoue T, Hirata K, Yanai S, Matsumoto T, Shimizu S, Miwa J, Sasaki Y, Yashima K, Ohnuma H, Sato Y, Kitayama Y, Ohda Y, Yamauchi A, Sanomura Y, Tanaka K, Kubo Y, Ishikawa H, Bando Y, Sonoda T, Takayama T.
- Int J Clin Oncol. 2022 Apr;27(4):639-647. doi: 10.1007/s10147-022-02116-w. Epub 2022 Feb 2.
- PMID: 35106660
- PubMed abstract
- Source abstract
-
- Analysis of pathogenic variants in BRCA1 and BRCA2 genes using next-generation sequencing in women with triple negative breast cancer from South India.
- Rajagopal T, Seshachalam A, Jothi A, Rathnam KK, Talluri S, Venkatabalasubranian S, Dunna NR.
- Mol Biol Rep. 2022 Apr;49(4):3025-3032. doi: 10.1007/s11033-022-07129-2. Epub 2022 Jan 12.
- PMID: 35020120
- PubMed abstract
- Source abstract
-
- Habitat Analysis of Breast Cancer-Enhanced MRI Reflects BRCA1 Mutation Determined by Immunohistochemistry.
- Du T, Zhao H.
- Biomed Res Int. 2022 Mar 30;2022:9623173. doi: 10.1155/2022/9623173.
- PMID: 35402620
- PubMed abstract
-
- Hereditary Diffuse Gastric Cancer-Update Based on the Current Consort Recommendations.
- Treese C, Siegmund B, Daum S.
- Curr Oncol. 2022 Mar 30;29(4):2454-2460. doi: 10.3390/curroncol29040199.
- PMID: 35448173
- PubMed abstract
- Source abstract
- Commentary
- Free Full Text
-
- PARP-1 Expression and BRCA1 Mutations in Breast Cancer Patients' CTCs.
- Sklias T, Vardas V, Pantazaka E, Christopoulou A, Georgoulias V, Kotsakis A, Vasilopoulos Y, Kallergi G.
- Cancers (Basel). 2022 Mar 29;14(7):1731. doi: 10.3390/cancers14071731.
- PMID: 35406503
- PubMed abstract
- Source abstract
-
- Breast Cancer Phenotype Associated With Li-Fraumeni Syndrome: A Brazilian Cohort Enriched by TP53 p.R337H Carriers.
- Sandoval RL, Polidorio N, Leite ACR, Cartaxo M, Pisani JP, Quirino CV, Cezana L, Pereira NG, Pereira AAL, Rossi BM, Achatz MI.
- Front Oncol. 2022 Mar 16;12:836937. doi: 10.3389/fonc.2022.836937.
- PMID: 35371985
- PubMed abstract
-
- Gene mutations associated with clinical characters in the tumors of breast cancer patients.
- Hao C, Wang C, Lu N, Zhao W, Li S, Zhang L, Meng W, Wang S, Tong Z, Zeng Y, Lu L.
- Front Oncol. 2022 Mar 14;12:778511. doi: 10.3389/fonc.2022.778511.
-
- Treatment Patterns, Safety, and Patient Reported Outcomes among Adult Women with Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer with or without or with Unknown BRCA1/2 Mutation(s): Results of a Real-World Study from the United States, United Kingdom, and Four EU Countries.
- Lux MP, Lewis K, Rider A, Niyazov A.
- Breast Care (Basel). 2022 Mar 11. doi: 10.1159/000523970. Epub ahead of print.
-
- Germline Mutation Analysis in Sporadic Breast Cancer Cases With Clinical Correlations.
- Ajaz S, Zaidi SE, Ali S, Siddiqa A, Memon MA.
- Front Genet. 2022 Mar 9;13:820610. doi: 10.3389/fgene.2022.820610.
- PMID: 35356428
- PubMed abstract
-
- [Application of next-generation sequencing in detection of BRCA1/2 and homologous recombination repair pathway multi-genes germline mutation and correlation analysis].
- Chen YL, Zhuo ZL, Liu C, Xie F, Yang ZY, Liu PF, Wang S, Zhao XT.
- Zhonghua Yu Fang Yi Xue Za Zhi. 2022 Mar 6;56(3):302-311. Chinese. doi: 10.3760/cma.j.cn112150-20211208-01132.
- PMID: 35381651
- PubMed abstract
-
- Li-Fraumeni syndrome in Tunisian carriers with different and rare tumor phenotype: genotype-phenotype correlation.
- Sassi H, Meddeb R, Cherif MA, Nasr C, Riahi A, Hannachi S, Belguith N, M'rad R.
- BMC Med Genomics. 2022 Mar 4;15(1):44. doi: 10.1186/s12920-022-01189-w.
- PMID: 35246108
- PubMed abstract
- Case report
- Free Full Text
-
- Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes.
- Breast Cancer Association Consortium, Mavaddat N, Dorling L, Carvalho S, Allen J, González-Neira A, Keeman R, Bolla MK, Dennis J, Wang Q, Ahearn TU, Andrulis IL, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Briceno I, Brüning T, Camp NJ, Campbell A, Castelao JE, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Christiansen H, Czene K, Dörk T, Eriksson M, Evans DG, Fasching PA, Figueroa JD, Flyger H, Gabrielson M, Gago-Dominguez M, Geisler J, Giles GG, Guénel P, Hadjisavvas A, Hahnen E, Hall P, Hamann U, Hartikainen JM, Hartman M, Hoppe R, Howell A, Jakubowska A, Jung A, Khusnutdinova EK, Kristensen VN, Li J, Lim SH, Lindblom A, Loizidou MA, Lophatananon A, Lubinski J, Madsen MJ, Mannermaa A, Manoochehri M, Margolin S, Mavroudis D, Milne RL, Mohd Taib NA, Morra A, Muir K, Obi N, Osorio A, Park-Simon TW, Peterlongo P, Radice P, Saloustros E, Sawyer EJ, Schmutzler RK, Shah M, Sim X, Southey MC, Thorne H, Tomlinson I, Torres D, Truong T, Yip CH, Spurdle AB, Vreeswijk MPG, Dunning AM, García-Closas M, Pharoah PDP, Kvist A, Muranen TA, Nevanlinna H, Teo SH, Devilee P, Schmidt MK, Easton DF.
- JAMA Oncol. 2022 Mar 1;8(3):e216744. doi: 10.1001/jamaoncol.2021.6744. Epub 2022 Mar 17.
- PMID: 35084436
- PubMed abstract
Press: Breast Tumor Features Reflecting Germline Variants May Improve Risk Prediction Models. (Precision Oncology News)
Research news: Variants of Nine Breast Cancer Genes Associated With Severe Disease. (Medscape)
-
- Recurrent Acromegaly in a Patient With a CHEK2 Mutation.
- Perosevic M, Martinez-Lage M, Swearingen B, Tritos NA.
- AACE Clin Case Rep. 2021 Nov 20 [eCollection Mar-Apr 2022];8(2):85-88. doi: 10.1016/j.aace.2021.10.006.
- PMID: 35415223
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- CDH1 germline variants are enriched in patients with colorectal cancer, gastric cancer, and breast cancer.
- Adib E, El Zarif T, Nassar AH, Akl EW, Abou Alaiwi S, Mouhieddine TH, Esplin ED, Hatchell K, Nielsen SM, Rana HQ, Choueiri TK, Kwiatkowski DJ, Sonpavde G.
- Br J Cancer. 2022 Mar;126(5):797-803. doi: 10.1038/s41416-021-01673-7. Epub 2021 Dec 23.
- PMID: 34949788
- PubMed abstract
-
- Racial and ethnic variation in multigene panel testing in a cohort of BRCA1/2-negative individuals who had genetic testing in a large urban comprehensive cancer center.
- Tatineni S, Tarockoff M, Abdallah N, Purrington KS, Assad H, Reagle R, Petrucelli N, Simon MS.
- Cancer Med. 2022 Mar;11(6):1465-1473. doi: 10.1002/cam4.4541. Epub 2022 Jan 17.
- PMID: 35040284
- PubMed abstract
- Source abstract
-
- Clinical outcomes and Oncotype DX Breast Recurrence Score® in early-stage BRCA-associated hormone receptor-positive breast cancer.
- Layman RM, Lin H, Gutierrez Barrera AM, Karuturi MS, Yam C, Arun BK.
- Cancer Med. 2022 Mar;11(6):1474-1483. doi: 10.1002/cam4.4566. Epub 2022 Feb 6.
- PMID: 35128817
- PubMed abstract
- Source abstract
-
- Impact of BRCA mutations and hormone receptor status on reproductive potential in breast cancer patients undergoing fertility preservation.
- Kim SW, Kim TH, Han JY, Kim SK, Lee JR, Jee UC, Suh CS, Kim SH.
- Gynecol Endocrinol. 2022 Mar;38(3):227-230. doi: 10.1080/09513590.2021.2002294. Epub 2021 Nov 13.
- PMID: 34775902
- PubMed abstract
- Source abstract
-
- Variants of Nine Breast Cancer Genes Associated With Severe Disease.
- Worcester S.
- Medscape. 2022 Feb 25.
- Research news
- Free Full Text
Original research:
Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes.
- PMID: 35084436
- PubMed abstract
- Free Full Text
-
- Germline pathogenic variants in Mexican patients with hereditary triple-negative breast cancer.
- Chavarri-Guerra Y, Villarreal-Garza C, Ferrigno AS, Mohar A, Aguilar D, Alvarez-Gomez RM, Gallardo-Alvarado L, Del Toro-Valero A, Quintero-Beulo G, Gutierrez-Delgado F, Rodriguez-Olivares JL, Ochoa-Chavez MF, Gutierrez-Seymour G, Castillo D, Herzog J, Weitzel JN.
- Salud Publica Mex. 2022 Feb 25;64(1):41-48. doi: 10.21149/12704.
- PMID: 35438911
- PubMed abstract
- Source abstract
-
- PTEN alterations in sporadic and BRCA1-associated triple negative breast carcinomas.
- Jones N, Gros A, Velasco V, Dapremont V, Brouste V, Gastaldello B, Debled M, de Lara CT, Bonnet F, Barouk-Simonet E, Bubien V, Venat L, MacGrogan G, Longy M, Sevenet N.
- Cancer Genet. 2022 Feb 24. doi: 10.1016/j.cancergen.2022.02.008. Epub ahead of print.
-
- The impact of race and ethnicity in breast cancer-disparities and implications for precision oncology.
- Hirko KA, Rocque G, Reasor E, Taye A, Daly A, Cutress RI, Copson ER, Lee DW, Lee KH, Im SA, Park YH.
- BMC Med. 2022 Feb 11;20(1):72. doi: 10.1186/s12916-022-02260-0.
- PMID: 35151316
- PubMed abstract
- Review
- Free Full Text
-
- Unique ER PR expression pattern in breast cancers with CHEK2 mutation: a hormone receptor and HER2 analysis based on germline cancer predisposition genes.
- Wei G, Teng M, Rosa M, Wang X.
- Breast Cancer Res. 2022 Feb 8;24(1):11. doi: 10.1186/s13058-022-01507-1.
- PMID: 35135604
- PubMed abstract
-
- Missed Breast Cancers on MRI in High-Risk Patients: A Retrospective Case-Control Study.
- Bilocq-Lacoste J, Ferre R, Kuling G, Martel AL, Tyrrell PN, Li S, Wang G, Curpen B.
- Tomography. 2022 Feb 2;8(1):329-340. doi: 10.3390/tomography8010027.
- PMID: 35202192
- PubMed abstract
- Source abstract
-
- ASO Author Reflections: Germline Testing for All Patients With Breast Cancer: Has the Time Finally Come?
- Mittal A, Pramanik R.
- Ann Surg Oncol. 2022 Feb;29(2):1433-1434. doi: 10.1245/s10434-021-10880-8. Epub 2021 Oct 15.
- PMID: 34654988
- PubMed abstract
-
- The CHEK2*1100delC Mutation and Adolescent Breast Cancer: A Case Report of Breast Cancer in a 19-Year-Old and a Review of the Literature.
- Soleimani T, Engwall AJ, Bourdon C, Torabi MA, Fortes T.
- Breast Care (Basel). 2022 Feb;17(1):85-89. doi: 10.1159/000513679. Epub 2021 Mar 8.
- PMID: 35355698
- PubMed abstract
- Source abstract
-
- Clinicopathological features and BRCA1 and BRCA2 mutation status in a prospective cohort of young women with breast cancer.
- Guzmán-Arocho YD, Rosenberg SM, Garber JE, Vardeh H, Poorvu PD, Ruddy KJ, Kirkner G, Snow C, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Brachtel EF, Marotti JD, Warner E, Partridge AH, Collins LC.
- Br J Cancer. 2022 Feb;126(2):302-309. doi: 10.1038/s41416-021-01597-2. Epub 2021 Oct 26.
- PMID: 34703009
- PubMed abstract
- Source abstract
-
- High likelihood of actionable pathogenic variant detection in breast cancer genes in women with very early onset breast cancer.
- Evans DG, van Veen EM, Byers HJ, Evans SJ, Burghel GJ, Woodward ER, Harkness EF, Eccles DM, Greville-Haygate SL, Ellingford JM, Bowers NL, Pereira M, Wallace AJ, Howell SJ, Howell A, Lalloo F, Newman WG, Smith MJ.
- J Med Genet. 2022 Feb;59(2):115-121. doi: 10.1136/jmedgenet-2020-107347. Epub 2021 Mar 23.
- PMID: 33758026
- PubMed abstract
-
- Novel Insights From the Germline Landscape of Breast Cancer in Brazil.
- Barbalho D, Sandoval R, Santos E, Pisani J, Quirino C, Garicochea B, Rossi B, Achatz MI.
- Front Oncol. 2022 Jan 28;11:743231. doi: 10.3389/fonc.2021.743231.
- PMID: 35155181
- PubMed abstract
-
- Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities.
- Cosgrove N, Varešlija D, Keelan S, Elangovan A, Atkinson JM, Cocchiglia S, Bane FT, Singh V, Furney S, Hu C, Carter JM, Hart SN, Yadav S, Goetz MP, Hill ADK, Oesterreich S, Lee AV, Couch FJ, Young LS.
- Nat Commun. 2022 Jan 26;13(1):514. doi: 10.1038/s41467-022-27987-5.
- PMID: 35082299
- PubMed abstract
-
- The Mutational Landscape of Early-Onset Breast Cancer: A Next-Generation Sequencing Analysis.
- Andrikopoulou A, Chatzinikolaou S, Kyriopoulos I, Bletsa G, Kaparelou M, Liontos M, Dimopoulos MA, Zagouri F.
- Front Oncol. 2022 Jan 21;11:797505. doi: 10.3389/fonc.2021.797505.
- PMID: 35127508
- PubMed abstract
-
- Real-world evidence of the management and prognosis of young women (<40 years) with de novo metastatic breast cancer.
- Mallet A, Lusque A, Levy C, Pistilli B, Brain E, Pasquier D, Debled M, Thery JC, Gonçalves A, Desmoulins I, De La Motte Rouge T, Faure C, Ferrero JM, Eymard JC, Mouret-Reynier MA, Patsouris A, Cottu P, Dalenc F, Petit T, Payen O, Uwer L, Guiu S, Sébastien Frenel J.
- Ther Adv Med Oncol. 2022 Jan 21;14:17588359211070362. doi: 10.1177/17588359211070362.
- PMID: 35082924
- PubMed abstract
- Source abstract
-
- Rare germline copy number variants (CNVs) and breast cancer risk.
- Dennis J, Tyrer JP, Walker LC, Michailidou K, Dorling L, Bolla MK, Wang Q, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Freeman LEB, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Brenner H, Castelao JE, Chang-Claude J, Chenevix-Trench G, Clarke CL; NBCS Collaborators, Collée JM; CTS Consortium, Couch FJ, Cox A, Cross SS, Czene K, Devilee P, Dörk T, Dossus L, Eliassen AH, Eriksson M, Evans DG, Fasching PA, Figueroa J, Fletcher O, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, García-Closas M, Giles GG, González-Neira A, Guénel P, Hahnen E, Haiman CA, Hall P, Hollestelle A, Hoppe R, Hopper JL, Howell A; ABCTB Investigators; kConFab/AOCS Investigators, Jager A, Jakubowska A, John EM, Johnson N, Jones ME, Jung A, Kaaks R, Keeman R, Khusnutdinova E, Kitahara CM, Ko YD, Kosma VM, Koutros S, Kraft P, Kristensen VN, Kubelka-Sabit K, Kurian AW, Lacey JV, Lambrechts D, Larson NL, Linet M, Ogrodniczak A, Mannermaa A, Manoukian S, Margolin S, Mavroudis D, Milne RL, Muranen TA, Murphy RA, Nevanlinna H, Olson JE, Olsson H, Park-Simon TW, Perou CM, Peterlongo P, Plaseska-Karanfilska D, Pylkäs K, Rennert G, Saloustros E, Sandler DP, Sawyer EJ, Schmidt MK, Schmutzler RK, Shibli R, Smeets A, Soucy P, Southey MC, Swerdlow AJ, Tamimi RM, Taylor JA, Teras LR, Terry MB, Tomlinson I, Troester MA, Truong T, Vachon CM, Wendt C, Winqvist R, Wolk A, Yang XR, Zheng W, Ziogas A, Simard J, Dunning AM, Pharoah PDP, Easton DF.
- Commun Biol. 2022 Jan 18;5(1):65. doi: 10.1038/s42003-021-02990-6.
- PMID: 35042965
- PubMed abstract
-
- Integration of tumour sequencing and case-control data to assess pathogenicity of RAD51C missense variants in familial breast cancer.
- Lim BWX, Li N, Rowley SM, Thompson ER, McInerny S, Zethoven M, Scott RJ, Devereux L, Sloan EK, James PA, Campbell IG.
- NPJ Breast Cancer. 2022 Jan 17;8(1):10. doi: 10.1038/s41523-021-00373-y.
- PMID: 35039523
- PubMed abstract
-
- Germline sequence variants contributing to cancer susceptibility in South African breast cancer patients of African ancestry.
- Eygelaar D, van Rensburg EJ, Joubert F.
- Sci Rep. 2022 Jan 17;12(1):802. doi: 10.1038/s41598-022-04791-1.
- PMID: 35039564
- PubMed abstract
-
- Morphologic and Genomic Characteristics of Breast Cancers Occurring in Individuals with Lynch Syndrome.
- Schwartz CJ, da Silva EM, Marra A, Gazzo AM, Selenica P, Rai VK, Mandelker D, Pareja F, Misyura M, D'Alfonso TM, Brogi E, Drullinsky P, Razavi P, Robson ME, Drago JZ, Wen HY, Zhang L, Weigelt B, Shia J, Reis-Filho JS, Zhang H.
- Clin Cancer Res. 2022 Jan 15;28(2):404-413. doi: 10.1158/1078-0432.CCR-21-2027. Epub 2021 Oct 19.
- PMID: 34667028
- PubMed abstract
- Source abstract
-
- Associations of genetic susceptibility to 16 cancers with risk of breast cancer overall and by intrinsic subtypes.
- Choi J, Jia G, Wen W, Tao R, Long J, Shu XO, Zheng W.
- HGG Adv. 2021 Dec 10 [eCollection 2022 Jan 13];3(1):100077. doi: 10.1016/j.xhgg.2021.100077.
- PMID: 35047862
- PubMed abstract
-
- Mutation landscape of Homologous Recombination Repair Genes in Epithelial Ovarian Cancer in China and its relationship with Clinicopathological Characteristics.
- Qianlan Y, Liu Y, Zhang L, Bao L, Bai Q, Cui Q, Xu J, Li M, Liu J, Chuai S, Ying J, Zhang Z, Zhou X.
- Front Oncol. 2022 Jan 12;10:709645. doi: 10.3389/fonc.2022.709645.
-
- Common variants in breast cancer risk loci predispose to distinct tumor subtypes.
- Ahearn TU, Zhang H, Michailidou K, Milne RL, Bolla MK, Dennis J, Dunning AM, Lush M, Wang Q, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Augustinsson A, Baten A, Becher H, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H, Brenner H, Brooks-Wilson A, Brüning T, Burwinkel B, Buys SS, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Clarke CL; NBCS Collaborators, Collée JM, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dörk T, Dwek M, Eccles DM, Evans DG, Fasching PA, Figueroa J, Floris G, Gago-Dominguez M, Gapstur SM, García-Sáenz JA, Gaudet MM, Giles GG, Goldberg MS, González-Neira A, Alnæs GIG, Grip M, Guénel P, Haiman CA, Hall P, Hamann U, Harkness EF, Heemskerk-Gerritsen BAM, Holleczek B, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Howell A; ABCTB Investigators; kConFab/AOCS Investigators, Jakimovska M, Jakubowska A, John EM, Jones ME, Jung A, Kaaks R, Kauppila S, Keeman R, Khusnutdinova E, Kitahara CM, Ko YD, Koutros S, Kristensen VN, Krüger U, Kubelka-Sabit K, Kurian AW, Kyriacou K, Lambrechts D, Lee DG, Lindblom A, Linet M, Lissowska J, Llaneza A, Lo WY, MacInnis RJ, Mannermaa A, Manoochehri M, Margolin S, Martinez ME, McLean C, Meindl A, Menon U, Nevanlinna H, Newman WG, Nodora J, Offit K, Olsson H, Orr N, Park-Simon TW, Patel AV, Peto J, Pita G, Plaseska-Karanfilska D, Prentice R, Punie K, Pylkäs K, Radice P, Rennert G, Romero A, Rüdiger T, Saloustros E, Sampson S, Sandler DP, Sawyer EJ, Schmutzler RK, Schoemaker MJ, Schöttker B, Sherman ME, Shu XO, Smichkoska S, Southey MC, Spinelli JJ, Swerdlow AJ, Tamimi RM, Tapper WJ, Taylor JA, Teras LR, Terry MB, Torres D, Troester MA, Vachon CM, van Deurzen CHM, van Veen EM, Wagner P, Weinberg CR, Wendt C, Wesseling J, Winqvist R, Wolk A, Yang XR, Zheng W, Couch FJ, Simard J, Kraft P, Easton DF, Pharoah PDP, Schmidt MK, García-Closas M, Chatterjee N.
- Breast Cancer Res. 2022 Jan 4;24(1):2. doi: 10.1186/s13058-021-01484-x.
- PMID: 34983606
- PubMed abstract
-
- The impact of young age (< 40 years) on the outcome of a cohort of patients with primary non-metastatic breast cancer: analysis of 10-year survival of a prospective study.
- Bouferraa Y, Haibe Y, Chedid A, Jabra E, Charafeddine M, Temraz S, Mukherji D, El Saghir N, Shamseddine A.
- BMC Cancer. 2022 Jan 3;22(1):27. doi: 10.1186/s12885-021-09100-z.
- PMID: 34980002
- PubMed abstract
-
- Non-BRCA Early-Onset Breast Cancer in Young Women.
- Gao Y, Samreen N, Heller SL.
- Radiographics. 2022 Jan-Feb;42(1):5-22. doi: 10.1148/rg.210109.
- PMID: 34990317
- PubMed abstract
- Source abstract
Commentary:
Invited Commentary: The Challenges of Early-Onset Breast Cancer.
- PMID: 34990330
- PubMed abstract
- Source abstract
-
- Metastatic ovarian carcinoma in breast cancer patients during risk-reducing salpingo-oophorectomy: Report of two cases.
- Shakya P, Bajracharya A, Shrestha S, Kharel S, Maharjan R, Shrestha AK.
- Ann Med Surg (Lond). 2021 Dec 6;73:103158. doi: 10.1016/j.amsu.2021.103158. eCollection 2022 Jan.
- PMID: 34976386
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Comparing breast cancer imaging characteristics of CHEK2 with BRCA1 and BRCA2 gene mutation carriers.
- Ghunaim H, Laenen A, De Keyzer F, Soens J, Keupers M, Postema S, Neven P, Van Ongeval C.
- Eur J Radiol. 2022 Jan;146:110074. doi: 10.1016/j.ejrad.2021.110074. Epub 2021 Nov 26.
- PMID: 34902667
- PubMed abstract
- Source abstract
-
- Homologous Recombination Deficiencies and Hereditary Tumors.
- Yamamoto H, Hirasawa A.
- Int J Mol Sci. 2021 Dec 29;23(1):348. doi: 10.3390/ijms23010348.
- PMID: 35008774
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- BRCA1 and Metastasis: Outcome of Defective DNA Repair.
- Krishnan R, Patel PS, Hakem R.
- Cancers (Basel). 2021 Dec 27;14(1):108. doi: 10.3390/cancers14010108.
- PMID: 35008272
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Validation of Breast Cancer Risk Models by Race/Ethnicity, Family History and Molecular Subtypes.
- McCarthy AM, Liu Y, Ehsan S, Guan Z, Liang J, Huang T, Hughes K, Semine A, Kontos D, Conant E, Lehman C, Armstrong K, Braun D, Parmigiani G, Chen J.
- Cancers (Basel). 2021 Dec 23;14(1):45. doi: 10.3390/cancers14010045.
- PMID: 35008209
- PubMed abstract
- Source abstract
-
- Association of Family Cancer History With Pathogenic Variants in Specific Breast Cancer Susceptibility Genes.
- Kurian AW, Abrahamse P, Ward KC, Hamilton AS, Deapen D, Berek JS, Hoang L, Yussuf A, Dolinsky J, Brown K, Slavin T, Hofer TP, Katz SJ.
- JCO Precis Oncol. 2021 Dec 22;5:PO.21.00261. doi: 10.1200/PO.21.00261.
- PMID: 34977446
- PubMed abstract
- Source abstract
-
- Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast.
- Yadav S, Hu C, Nathanson KL, Weitzel JN, Goldgar DE, Kraft P, Gnanaolivu RD, Na J, Huang H, Boddicker NJ, Larson N, Gao C, Yao S, Weinberg C, Vachon CM, Trentham-Dietz A, Taylor JA, Sandler DR, Patel A, Palmer JR, Olson JE, Neuhausen S, Martinez E, Lindstrom S, Lacey JV, Kurian AW, John EM, Haiman C, Bernstein L, Auer PW, Anton-Culver H, Ambrosone CB, Karam R, Chao E, Yussuf A, Pesaran T, Dolinsky JS, Hart SN, LaDuca H, Polley EC, Domchek SM, Couch FJ.
- J Clin Oncol. 2021 Dec 10;39(35):3918-3926. doi: 10.1200/JCO.21.00640. Epub 2021 Oct 21.
- PMID: 34672684
- PubMed abstract
- Source abstract
-
- Germline breast cancer susceptibility genes, tumor characteristics, and survival.
- Ho PJ, Khng AJ, Loh HW, Ho WK, Yip CH, Mohd-Taib NA, Tan VKM, Tan BK, Tan SM, Tan EY, Lim SH, Jamaris S, Sim Y, Wong FY, Ngeow J, Lim EH, Tai MC, Wijaya EA, Lee SC, Chan CW, Buhari SA, Chan PMY, Chen JJC, Seah JCM, Lee WP, Mok CW, Lim GH, Woo E, Kim SW, Lee JW, Lee MH, Park SK, Dunning AM, Easton DF, Schmidt MK, Teo SH, Li J, Hartman M.
- Genome Med. 2021 Dec 2;13(1):185. doi: 10.1186/s13073-021-00978-9.
- PMID: 34857041
- PubMed abstract
-
- Familial Breast Cancer: Disease Related Gene Mutations and Screening Strategies for Chinese Population.
- Shen L, Zhang S, Wang K, Wang X.
- Front Oncol. 2021 Dec 1;11:740227. doi: 10.3389/fonc.2021.740227.
- PMID: 34926254
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
Commentary:
Editorial: Familial Cancer in China: From Detection to Screening and Management.
- PMID: 35574380
- PubMed abstract
- Free Full Text
-
- Genetic heterogeneity during breast cancer progression in young patients.
- Hagio K, Hatanaka KC, Amano T, Matsuno Y, Hatanaka Y, Yamashita H.
- Breast. 2021 Dec;60:206-213. doi: 10.1016/j.breast.2021.10.011. Epub 2021 Oct 28.
- PMID: 34736091
- PubMed abstract
-
- Prognostic difficulties of men with breast cancer.
- Fentiman IS.
- Breast J. 2021 Dec;27(12):877-882. doi: 10.1111/tbj.14297. Epub 2021 Oct 15.
- PMID: 34652050
- PubMed abstract
- Source abstract
-
- Epidemiology of Ductal Carcinoma In Situ.
- Iatrakis G, Zervoudis S.
- Chirurgia (Bucur). 2021 Dec;116(500):S15-S21. doi: 10.21614/chirurgia.116.5.suppl.S15.
- PMID: 34967307
- PubMed abstract
- Source abstract
- Review
- Free Full Text (PDF)
-
- Pathogenicity of VHL variants in families with non-syndromic von Hippel-Lindau phenotypes: An integrated evaluation of germline and somatic genomic results.
- Rana HQ, Koeller DR, Schwartz A, Manning DK, Schneider KA, Krajewski KM, Choueiri TK, Lindeman NI, Garber JE, Ghazani AA.
- Eur J Med Genet. 2021 Dec;64(12):104359. doi: 10.1016/j.ejmg.2021.104359. Epub 2021 Oct 8.
- PMID: 34628056
- PubMed abstract
- Source abstract
-
- [A Case of Recurrent Breast Cancer with Improving Activities of Daily Living by Olaparib Treatment].
- Nakagawa T, Oda G, Okamoto K, Ishikawa T, Wakana K, Oshima N.
- Gan To Kagaku Ryoho. 2021 Dec;48(13):1556-1558. Japanese.
- PMID: 35046254
- PubMed abstract
- Source abstract
-
- [Two Cases of Hereditary Breast Cancer in Which Genetic Counseling Was Useful].
- Sasaki A, Nagata T, Okamoto Y, Watanabe M, Saida Y.
- Gan To Kagaku Ryoho. 2021 Dec;48(13):1589-1591. Japanese.
- PMID: 35046265
- PubMed abstract
- Source abstract
-
- [A Case of Metastatic Breast Cancer with BRCA1 Mutation after Breast Reconstruction and Pregnancy].
- Suzuki T, Hashimoto N, Yokoyama K, Yoshida T, Yamauchi Y, Sawano T, Ohashi M, Kimura A, Kato M, Umehara Y, Murata A, Takahash K.
- Gan To Kagaku Ryoho. 2021 Dec;48(13):1840-1842. Japanese.
- PMID: 35046348
- PubMed abstract
- Source abstract
-
- [Hereditary Breast and Ovarian Cancer(HBOC)in a Young Adult-A Case Report].
- Adachi K, Kubota H, Suzuki S, Hirano T, Ishibashi N, Sakurai K.
- Gan To Kagaku Ryoho. 2021 Dec;48(13):1843-1845. Japanese.
- PMID: 35046349
- PubMed abstract
- Source abstract
-
- Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing Suggestions.
- Su Y, Yao Q, Xu Y, Yu C, Zhang J, Wang Q, Li J, Shi D, Yu B, Zeng Y, Zhu X, Bai Q, Zhou X.
- Front Genet. 2021 Nov 30;12:674094. doi: 10.3389/fgene.2021.674094.
- PMID: 34917121
- PubMed abstract
-
- A Case of Triple-Negative Breast Cancer with Germline Pathogenic Variants in Both BRCA1 and BRCA2.
- Kitahara M, Hozumi Y, Machinaga M, Hayashi Y.
- Case Rep Oncol. 2021 Nov 18;14(3):1645-1651. doi: 10.1159/000520148.
- PMID: 35082620
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Examining the Prevalence of Homologous Recombination Repair Defects in ER+ Breast Cancers.
- Moore GM, Powell SN, Higginson DS, Khan AJ.
- Int J Radiat Oncol Biol Phys. 2021 Nov 1;111(3S):S35-S36. doi: 10.1016/j.ijrobp.2021.07.106.
- PMID: 34700541
- PubMed abstract
- Conference abstract
- Free Full Text
-
- Changing Patterns in Clinicopathological Characteristics of Breast Cancer and Prevalence of BRCA Mutations: Analysis in a Rural Area of Southern China.
- Wang Q, Wu H, Lan Y, Zhang J, Wu J, Zhang Y, Li L, Liu D, Zhang J.
- Int J Gen Med. 2021 Oct 29;14:7371-7380. doi: 10.2147/IJGM.S333858.
- PMID: 34744450
- PubMed abstract
-
- Expression of PD-L1 and BRCA1 in Triple-Negative Breast Cancer Patients and Relationship with Clinicopathological Characteristics.
- Huang X, Wang X, Qian H, Jin X, Jiang G.
- Evid Based Complement Alternat Med. 2021 Oct 22;2021:5314016. doi: 10.1155/2021/5314016.
- PMID: 34721634
- PubMed abstract
-
- Prognostic Prediction of BRCA Mutations by 18F-FDG PET/CT SUVmax in Breast Cancer.
- Özdemir S, Silan F, Akgün MY, Araci N, Çirpan I, Koç Öztürk F, Özdemir Ö.
- Mol Imaging Radionucl Ther. 2021 Oct 15;30(3):158-168. doi: 10.4274/mirt.galenos.2021.82584.
- PMID: 34658299
- PubMed abstract
-
- Peutz-Jeghers Syndrome and the Role of Imaging: Pathophysiology, Diagnosis, and Associated Cancers.
- Klimkowski S, Ibrahim M, Ibarra Rovira JJ, Elshikh M, Javadi S, Klekers AR, Abusaif AA, Moawad AW, Ali K, Elsayes KM.
- Cancers (Basel). 2021 Oct 13;13(20):5121. doi: 10.3390/cancers13205121.
- PMID: 34680270
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Association Between Hereditary Lobular Breast Cancer Due to CDH1 Variants and Gastric Cancer Risk.
- Gamble LA, Rossi A, Fasaye GA, Kesserwan C, Hernandez JM, Blakely AM, Davis JL.
- JAMA Surg. 2021 Oct 13. doi: 10.1001/jamasurg.2021.5118. Epub ahead of print.
- PMID: 34643667
- PubMed abstract
- Source abstract
-
- Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.
- Setton J, Selenica P, Mukherjee S, Shah R, Pecorari I, McMillan B, Pei IX, Kemel Y, Ceyhan-Birsoy O, Sheehan M, Tkachuk K, Brown DN, Zhang L, Cadoo K, Powell S, Weigelt B, Robson M, Riaz N, Offit K, Reis-Filho JS, Mandelker D.
- NPJ Breast Cancer. 2021 Oct 11;7(1):135. doi: 10.1038/s41523-021-00339-0.
- PMID: 34635660
- PubMed abstract
-
- Profile of Pathogenic Mutations and Evaluation of Germline Genetic Testing Criteria in Consecutive Breast Cancer Patients Treated at a North Indian Tertiary Care Center.
- Mittal A, Deo SVS, Gogia A, Batra A, Kumar A, Bhoriwal S, Deb KS, Dhamija E, Thulkar S, Ramprasad VL, Olopade O, Pramanik R.
- Ann Surg Oncol. 2021 Oct 2:1–10. doi: 10.1245/s10434-021-10870-w. Epub ahead of print.
- PMID: 34601666
- PubMed abstract
-
- Pioneering BRCA1/2 Point-Of-Care Testing for Integration of Germline and Tumor Genetics in Breast Cancer Risk Management: A Vision for the Future of Translational Pharmacogenomics.
- Mampunye L, van der Merwe NC, Grant KA, Peeters AV, Torrorey-Sawe R, French DJ, Moremi KE, Kidd M, van Eeden PC, Pienaar FM, Kotze MJ.
- Front Oncol. 2021 Sep 29;11:619817. doi: 10.3389/fonc.2021.619817.
- PMID: 34660253
- PubMed abstract
-
- Protein truncating variants in FANCM and risk for ER-negative/triple negative breast cancer.
- Peterlongo P, Figlioli G, Deans AJ, Couch FJ.
- NPJ Breast Cancer. 2021 Sep 28;7(1):130. doi: 10.1038/s41523-021-00338-1.
- PMID: 34584094
- PubMed abstract
- Commentary
- Free PMC article
- Free Full Text
-
- Harnessing DNA Repair Defects to Augment Immune-Based Therapies in Triple-Negative Breast Cancer.
- Clark CA, Yang ES.
- Front Oncol. 2021 Sep 24;11:703802. doi: 10.3389/fonc.2021.703802.
- PMID: 34631532
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Spectrum of Germline Pathogenic Variants in BRCA1/2 Genes in the Apulian Southern Italy Population: Geographic Distribution and Evidence for Targeted Genetic Testing.
- Patruno M, De Summa S, Resta N, Caputo M, Costanzo S, Digennaro M, Pilato B, Bagnulo R, Pantaleo A, Simone C, Natalicchio MI, De Matteis E, Tarantino P, Tommasi S, Paradiso A.
- Cancers (Basel). 2021 Sep 21;13(18):4714. doi: 10.3390/cancers13184714.
- PMID: 34572941
- PubMed abstract
- Source abstract
-
- Identification of a novel pathogenic variant in PALB2 and BARD1 genes by a multigene sequencing panel in triple negative breast cancer in Morocco.
- Laraqui A, Cavaillé M, Uhrhammer N, ElBiad O, Bidet Y, El Rhaffouli H, El Anaz H, Rahali DM, Kouach J, Guelzim K, Badaoui B, AlBouzidi A, Oukabli M, Tanz R, Sbitti Y, Ichou M, Ennibi K, Sekhsokh Y, Bignon YJ.
- J Genomics. 2021 Sep 18;9:43-54. doi: 10.7150/jgen.61713.
- PMID: 34646395
- PubMed abstract
- Source abstract
-
- Risks of subsequent primary cancers among breast cancer survivors according to hormone receptor status.
- Sung H, Freedman RA, Siegel RL, Hyun N, DeSantis CE, Ruddy KJ, Jemal A.
- Cancer. 2021 Sep 15;127(18):3310-3324. doi: 10.1002/cncr.33602. Epub 2021 May 18.
- PMID: 34002851
- PubMed abstract
- Source abstract
-
- Cancer Spectrum, Family History of Cancer and Overall Survival in Men with Germline BRCA1 or BRCA2 Mutations.
- Reichl F, Muhr D, Rebhan K, Kramer G, Shariat SF, Singer CF, Tan YY.
- J Pers Med. 2021 Sep 15;11(9):917. doi: 10.3390/jpm11090917.
- PMID: 34575694
- PubMed abstract
- Source abstract
-
- Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression.
- Fores-Martos J, Cervera-Vidal R, Sierra-Roca J, Lozano-Asencio C, Fedele V, Cornelissen S, Edvarsen H, Tadeo-Cervera I, Eroles P, Lluch A, Tabares-Seisdedos R, Falcó A, Van't Veer LJ, Schmidt M, Quigley DA, Børresen-Dale AL, Kristensen VN, Balmain A, Climent J.
- NPJ Breast Cancer. 2021 Sep 10;7(1):118. doi: 10.1038/s41523-021-00329-2.
- PMID: 34508103
- PubMed abstract
-
- Transcriptome of Male Breast Cancer Matched with Germline Profiling Reveals Novel Molecular Subtypes with Possible Clinical Relevance.
- Zelli V, Silvestri V, Valentini V, Bucalo A, Rizzolo P, Zanna I, Bianchi S, Coppa A, Giannini G, Cortesi L, Calistri D, Tibiletti MG, Fox SB, Fab K, Palli D, Ottini L.
- Cancers (Basel). 2021 Sep 8;13(18):4515. doi: 10.3390/cancers13184515.
- PMID: 34572741
- PubMed abstract
- Source abstract
-
- Germline Genetic Testing for Women With Breast Cancer: Shifting the Paradigm From Whom to Test to Whom NOT to Test.
- Tung N, Desai N.
- J Clin Oncol. 2021 Sep 7:JCO2101761. doi: 10.1200/JCO.21.01761. Epub ahead of print.
- PMID: 34491781
- PubMed abstract
- Commentary, Research news
- Free Full Text
Original research:
Risk of Late-Onset Breast Cancer in Genetically Predisposed Women.
- PMID: 34292776
- PubMed abstract
- Free Full Text
Original research:
Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer.
- PMID: 32125938
- PubMed abstract
- Free Full Text
-
- Analysis of mutation status and homologous recombination deficiency in tumors of patients with germline BRCA1 or BRCA2 mutations and metastatic breast cancer: OlympiAD.
- Hodgson D, Lai Z, Dearden S, Barrett JC, Harrington EA, Timms K, Lanchbury J, Wu W, Allen A, Senkus E, Domchek SM, Robson M.
- Ann Oncol. 2021 Sep 6:S0923-7534(21)04458-6. doi: 10.1016/j.annonc.2021.08.2154. Epub ahead of print.
- PMID: 34500047
- PubMed abstract
- Source abstract
-
- "High-Risk Breast Cancer Screening in BRCA1/2 Carriers Leads to Early Detection and Improved Survival After a Breast Cancer Diagnosis".
- Shraga S, Grinshpun A, Zick A, Kadouri L, Cohen Y, Maimon O, Adler-Levy Y, Zeltzer G, Granit A, Maly B, Carmon E, Meiner V, Sella T, Hamburger T, Peretz T.
- Front Oncol. 2021 Sep 2;11:683656. doi: 10.3389/fonc.2021.683656.
- PMID: 34540661
- PubMed abstract
-
- Prevalence of mutations in BRCA and homologous recombination repair genes and real-world standard of care of Asian patients with HER2-negative metastatic breast cancer starting first-line systemic cytotoxic chemotherapy: subgroup analysis of the global BREAKOUT study.
- Koh SJ, Ohsumi S, Takahashi M, Fukuma E, Jung KH, Ishida T, Dai MS, Chang CH, Dalvi T, Walker G, Bennett J, O'Shaughnessy J, Balmaña J.
- Breast Cancer. 2021 Aug 31. doi: 10.1007/s12282-021-01283-4. Epub ahead of print.
- PMID: 34467476
- PubMed abstract
- Source abstract
-
- Male breast cancer: an update.
- Fox S, Speirs V, Shaaban AM.
- Virchows Arch. 2021 Aug 30. doi: 10.1007/s00428-021-03190-7. Epub ahead of print.
- PMID: 34458944
- PubMed abstract
- Source abstract
-
- Germline PALB2 Mutation in High-Risk Chinese Breast and/or Ovarian Cancer Patients.
- Kwong A, Shin VY, Ho CYS, Khalid A, Au CH, Chan KKL, Ngan HYS, Chan TL, Ma ESK.
- Cancers (Basel). 2021 Aug 20;13(16):4195. doi: 10.3390/cancers13164195.
- PMID: 34439348
- PubMed abstract
- Source abstract
-
- Cancer predisposition and germline CTNNA1 variants.
- Lobo S, Benusiglio PR, Coulet F, Boussemart L, Golmard L, Spier I, Hüneburg R, Aretz S, Colas C, Oliveira C.
- Eur J Med Genet. 2021 Aug 20:104316. doi: 10.1016/j.ejmg.2021.104316. Epub ahead of print.
- PMID: 34425242
- PubMed abstract
- Source abstract
-
- Identification of Eleven Novel BRCA Mutations in Tunisia: Impact on the Clinical Management of BRCA Related Cancers.
- Hamdi Y, Mighri N, Boujemaa M, Mejri N, Ben Nasr S, Ben Rekaya M, Messaoud O, Bouaziz H, Berrazega Y, Rachdi H, Jaidane O, Daoud N, Zribi A, Ayari J, El Benna H, Labidi S, Ben Hassouna J, Haddaoui A, Rahal K, Benna F, Mrad R, Ben Ahmed S, Boussen H, Boubaker S, Abdelhak S.
- Front Oncol. 2021 Aug 20;11:674965. doi: 10.3389/fonc.2021.674965.
- PMID: 34490083
- PubMed abstract
-
- Effect and Safety of Therapeutic Regimens for Patients With Germline BRCA Mutation-Associated Breast Cancer: A Network Meta-Analysis.
- Jiang Y, Meng XY, Deng NN, Meng C, Li LH, He ZK, Wang XY, Song ZY, Cui RJ.
- Front Oncol. 2021 Aug 20;11:718761. doi: 10.3389/fonc.2021.718761.
- PMID: 34490117
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Genetic Variants and Tumor Immune Microenvironment: Clues for Targeted Therapies in Inflammatory Breast Cancer (IBC).
- Gong Y, Nagarathinam R, Arisi MF, Gerratana L, Winn JS, Slifker M, Pei J, Cai KQ, Hasse Z, Obeid E, Noriega J, Sebastiano C, Ross E, Alpaugh K, Cristofanilli M, Fernandez SV.
- Int J Mol Sci. 2021 Aug 19;22(16):8924. doi: 10.3390/ijms22168924.
- PMID: 34445631
- PubMed abstract
- Source abstract
-
- Genetic epidemiology of BRCA1- and BRCA2-associated cancer across Latin America.
- Herzog JS, Chavarri-Guerra Y, Castillo D, Abugattas J, Villarreal-Garza C, Sand S, Clague-Dehart J, Alvarez-Gómez RM, Wegman-Ostrosky T, Mohar A, Mora P, Del Toro-Valero A, Daneri-Navarro A, Rodriguez Y, Cruz-Correa M, Ashton-Prolla P, Alemar B, Mejia R, Gallardo L, Shaw R, Yang K, Cervantes A, Tsang K, Nehoray B, Barrera Saldana H, Neuhausen S, Weitzel JN.
- NPJ Breast Cancer. 2021 Aug 19;7(1):107. doi: 10.1038/s41523-021-00317-6.
- PMID: 34413315
- PubMed abstract
-
- Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
- Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn TU, Andrulis IL, Anton-Culver H, Arndt V, Auer PL, Augustinsson A, Beane Freeman LE, Becher H, Beckmann MW, Behrens S, Bojesen SE, Bolla MK, Brenner H, Brüning T, Buys SS, Caan B, Campa D, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Cheng TD, Clarke CL; NBCS Collaborators, Colonna SV, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Dennis J, Dörk T, Dossus L, Dunning AM, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Eriksson M, Evans DG, Fasching PA, Flyger H, Fritschi L, Gago-Dominguez M, García-Sáenz JA, Giles GG, Grip M, Guénel P, Gündert M, Hahnen E, Haiman CA, Håkansson N, Hall P, Hamann U, Hart SN, Hartikainen JM, Hartmann A, He W, Hooning MJ, Hoppe R, Hopper JL, Howell A, Hunter DJ; ABCTB Investigators; kConFab Investigators, Jager A, Jakubowska A, Janni W, John EM, Jung AY, Kaaks R, Keupers M, Kitahara CM, Koutros S, Kraft P, Kristensen VN, Kurian AW, Lacey JV, Lambrechts D, Le Marchand L, Lindblom A, Linet M, Luben RN, Lubinski J, Lush M, Mannermaa A, Manoochehri M, Margolin S, Martens JWM, Martinez ME, Mavroudis D, Michailidou K, Milne RL, Mulligan AM, Muranen TA, Nevanlinna H, Newman WG, Nielsen SF, Nordestgaard BG, Olshan AF, Olsson H, Orr N, Park-Simon TW, Patel AV, Peissel B, Peterlongo P, Plaseska-Karanfilska D, Prajzendanc K, Prentice R, Presneau N, Rack B, Rennert G, Rennert HS, Rhenius V, Romero A, Roylance R, Ruebner M, Saloustros E, Sawyer EJ, Schmutzler RK, Schneeweiss A, Scott C, Shah M, Smichkoska S, Southey MC, Stone J, Surowy H, Swerdlow AJ, Tamimi RM, Tapper WJ, Teras LR, Terry MB, Tollenaar RAEM, Tomlinson I, Troester MA, Truong T, Vachon CM, Wang Q, Hurson AN, Winqvist R, Wolk A, Ziogas A, Brauch H, García-Closas M, Pharoah PDP, Easton DF, Chenevix-Trench G, Schmidt MK.
- Breast Cancer Res. 2021 Aug 18;23(1):86. doi: 10.1186/s13058-021-01450-7.
- PMID: 34407845
- PubMed abstract
-
- Gene Panel Testing for Breast Cancer Reveals Differential Effect of Prior BRCA1/2 Probability.
- Evans DG, van Veen EM, Woodward ER, Harkness EF, Ellingford JM, Bowers NL, Wallace AJ, Howell SJ, Howell A, Lalloo F, Newman WG, Smith MJ.
- Cancers (Basel). 2021 Aug 18;13(16):4154. doi: 10.3390/cancers13164154.
- PMID: 34439310
- PubMed abstract
- Source abstract
-
- Study: Frequency of inherited mutations linked to breast cancer are similar in Black and white women.
- [No author given]
- FORCE. XRAY. 2021 Aug 13.
- Research news
- Free Full Text
Original research:
Comparison of the Prevalence of Pathogenic Variants in Cancer Susceptibility Genes in Black Women and Non-Hispanic White Women With Breast Cancer in the United States.
- PMID: 34042955
- PubMed abstract
- Source abstract
-
- Identification of BRCA2 Cis Double Heterozygous Breast Cancer Cases Using Whole Exome Sequencing: Phenotypic Expression and Impact on Personalized Oncology.
- Hamdi Y, Boujemaa M, Mighri N, Mejri N, Jaidane O, Ben Nasr S, Bouaziz H, Hassouna JB, Zribi A, Berrazaga Y, Rachdi H, Daoud N, El Benna H, Labidi S, Haddaoui A, Rahal K, Benna F, Boussen H, Abdelhak S, Boubaker S.
- Front Genet. 2021 Aug 12;12:674990. doi: 10.3389/fgene.2021.674990.
- PMID: 34456966
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Association of Genetic Testing Results with Mortality Among Women with Breast Cancer or Ovarian Cancer.
- Kurian AW, Abrahamse P, Bondarenko I, Hamilton AS, Deapen D, Gomez SL, Morrow M, Berek JS, Hofer TP, Katz SJ, Ward KC.
- J Natl Cancer Inst. 2021 Aug 9:djab151. doi: 10.1093/jnci/djab151. Epub ahead of print.
- PMID: 34373918
- PubMed abstract
- Source abstract
-
- Risks and Function of Breast Cancer Susceptibility Alleles.
- Torabi Dalivandan S, Plummer J, Gayther SA.
- Cancers (Basel). 2021 Aug 5;13(16):3953. doi: 10.3390/cancers13163953.
- PMID: 34439109
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Optimization of prediction methods for risk assessment of pathogenic germline variants in the Japanese population.
- Senda N, Kawaguchi-Sakita N, Kawashima M, Inagaki-Kawata Y, Yoshida K, Takada M, Kataoka M, Torii M, Nishimura T, Kawaguchi K, Suzuki E, Kataoka Y, Matsumoto Y, Yoshibayashi H, Yamagami K, Tsuyuki S, Takahara S, Yamauchi A, Shinkura N, Kato H, Moriguchi Y, Okamura R, Kan N, Suwa H, Sakata S, Mashima S, Yotsumoto F, Tachibana T, Tanaka M, Togashi K, Haga H, Yamada T, Kosugi S, Inamoto T, Sugimoto M, Ogawa S, Toi M.
- Cancer Sci. 2021 Aug;112(8):3338-3348. doi: 10.1111/cas.14986. Epub 2021 Jun 28.
- PMID: 34036661
- PubMed abstract
- Source abstract
-
- Clinicopathological Features of BRCA1/2 Mutation-Positive Breast Cancer.
- Paik HJ, Jung YJ, Kim DI, Lee S, Jung CS, Kang SK, Kim JJ, Oh SY, Joo JH, Kim HY.
- Oncology. 2021 [Aug];99(8):499-506. doi: 10.1159/000515790. Epub 2021 Jun 7.
- PMID: 34098565
- PubMed abstract
- Source abstract
-
- The other side of the coin: dissecting molecular mechanisms behind hereditary breast cancer in search of therapeutic opportunities.
- Stella S, Martorana F, Manzella L, Vigneri P.
- Transl Oncol. 2021 Aug;14(8):101104. doi: 10.1016/j.tranon.2021.101104. Epub 2021 May 13.
- PMID: 33993096
- PubMed abstract
- Commentary
- Free PMC article
- Free Full Text
Original research:
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.
- PMID: 33471991
- PubMed abstract
- Free Full Text
Original research:
A Population-Based Study of Genes Previously Implicated in Breast Cancer.
- PMID: 33471974
- PubMed abstract
- Free Full Text
-
- Breast cancer incidence and early diagnosis in a family history risk and prevention clinic: 33-year experience in 14,311 women.
- Evans DG, Howell SJ, Gandhi A, van Veen EM, Woodward ER, Harvey J, Barr L, Wallace A, Lalloo F, Wilson M, Hurley E, Lim Y, Maxwell AJ, Harkness EF, Howell A.
- Breast Cancer Res Treat. 2021 Jul 26. doi: 10.1007/s10549-021-06333-1. Epub ahead of print.
- PMID: 34312777
- PubMed abstract
-
- Risk of Late-Onset Breast Cancer in Genetically Predisposed Women.
- Boddicker NJ, Hu C, Weitzel JN, Kraft P, Nathanson KL, Goldgar DE, Na J, Huang H, Gnanaolivu RD, Larson N, Yussuf A, Yao S, Vachon CM, Trentham-Dietz A, Teras L, Taylor JA, Scott CE, Sandler DP, Pesaran T, Patel AV, Palmer JR, Ong IM, Olson JE, O'Brien K, Neuhausen S, Martinez E, Ma H, Lindstrom S, Le Marchand L, Kooperberg C, Karam R, Hunter DJ, Hodge JM, Haiman C, Gaudet MM, Gao C, LaDuca H, Lacey JV, Dolinsky JS, Chao E, Carter BD, Burnside ES, Bertrand KA, Bernstein L, Auer PW, Ambrosone C, Yadav S, Hart SN, Polley EC, Domchek SM, Couch FJ.
- J Clin Oncol. 2021 Jul 22:JCO2100531. doi: 10.1200/JCO.21.00531. Epub ahead of print.
- PMID: 34292776
- PubMed abstract
- Source abstract
Commentary, Research report:
Germline Genetic Testing for Women With Breast Cancer: Shifting the Paradigm From Whom to Test to Whom NOT to Test.
- PMID: 34491781
- PubMed abstract
- Free Full Text
Press: Older Women with Breast Cancer May Benefit from Genetic Testing (Clinical OMICs)
-
- Increased gene expression variability in BRCA1-associated and basal-like breast tumours.
- Wiggins GAR, Black MA, Dunbier A, Morley-Bunker AE; kConFab Investigators, Pearson JF, Walker LC.
- Breast Cancer Res Treat. 2021 Jul 21. doi: 10.1007/s10549-021-06328-y. Epub ahead of print.
- PMID: 34287743
- PubMed abstract
-
- Prevalence and predictors of germline BRCA1 and BRCA2 mutations among young patients with breast cancer in Jordan.
- Abdel-Razeq H, Abujamous L, Abunasser M, Edaily S, Bater R.
- Sci Rep. 2021 Jul 21;11(1):14906. doi: 10.1038/s41598-021-94403-1.
- PMID: 34290354
- PubMed abstract
-
- OncotypeDX© Recurrence Score in BRCA mutation carriers: a systematic review and meta-analysis.
- Davey MG, Richard V, Lowery AJ, Kerin MJ.
- Eur J Cancer. 2021 Jul 17;154:209-216. doi: 10.1016/j.ejca.2021.06.032. Epub ahead of print.
- PMID: 34284256
- PubMed abstract
-
- Germline and Somatic mutations in postmenopausal breast cancer patients.
- Nagy TR, Maistro S, Encinas G, Katayama MLH, Pereira GFL, Gaburo-Júnior N, Franco LAM, Gouvêa ACRC, Diz MDPE, Leite LAS, Folgueira MAAK.
- Clinics (Sao Paulo). 2021 Jul 16;76:e2837. doi: 10.6061/clinics/2021/e2837.
- PMID: 34287479
- PubMed abstract
- Source abstract
-
- Results from London Regional Clinical Genetics services over a 5-year period on germline TP53 testing in women diagnosed with breast cancer at <30 years.
- Garrett A, Talukdar S, Izatt L, Brady AF, Whyte S, Josephs KS, Shanmugasundaram M, Guillemot LS, Vakili D, Ey S, Ahmed M.
- J Med Genet. 2021 Jul 15:jmedgenet-2021-107742. doi: 10.1136/jmedgenet-2021-107742. Epub ahead of print.
- PMID: 34266904
- PubMed abstract
- Source abstract
-
- A novel germline BRCA1 mutation identified in a family with hereditary breast and ovarian cancer syndrome.
- Wu Y, Pan X, Dou J, Zhang Q, Li Y, Sheng Y, Liu X.
- Clin Med Insights Oncol. 2021 Jul 2;15:11795549211028569. doi: 10.1177/11795549211028569.
- PMID: 34276234
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Comparison of the Prevalence of Pathogenic Variants in Cancer Susceptibility Genes in Black Women and Non-Hispanic White Women With Breast Cancer in the United States.
- Domchek SM, Yao S, Chen F, Hu C, Hart SN, Goldgar DE, Nathanson KL, Ambrosone CB, Haiman CA, Couch FJ, Polley EC, Palmer JR; CARRIERS Consortium.
- JAMA Oncol. 2021 Jul 1;7(7):1045-1050. doi: 10.1001/jamaoncol.2021.1492.
- PMID: 34042955
- PubMed abstract
- Source abstract
Research news: Study: Frequency of inherited mutations linked to breast cancer are similar in Black and white women. (FORCE. XRAY)
Research news: UPenn Study Finds Similar Rates of Risk Mutations Among Black, White Breast Cancer Patients. (Precision Oncology News)
-
- Molecular Features and Functional Implications of Germline Variants in Triple-Negative Breast Cancer.
- Ma D, Chen SY, Ren JX, Pei YC, Jiang CW, Zhao S, Xiao Y, Xu XE, Liu GY, Hu X, Liang XZ, Yu KD, Li DQ, Jiang YZ, Shao ZM.
- J Natl Cancer Inst. 2021 Jul 1;113(7):884-892. doi: 10.1093/jnci/djaa175. Erratum in: J Natl Cancer Inst. 2021 Aug 17.
- PMID: 33151324
- PubMed abstract
- Source abstract
-
- DAGM: A novel modelling framework to assess the risk of HER2-negative breast cancer based on germline rare coding mutations.
- Yang M, Fan Y, Wu ZY, Gu J, Feng Z, Zhang Q, Han S, Zhang Z, Li X, Hsueh YC, Ni Y, Li X, Li J, Hu M, Li W, Gao H, Yang C, Zhang C, Zhang L, Zhu T, Cheng M, Ji F, Xu J, Cui H, Tan G, Zhang MQ, Liang C, Liu Z, Song YQ, Niu G, Wang K.
- EBioMedicine. 2021 Jul;69:103446. doi: 10.1016/j.ebiom.2021.103446. Epub 2021 Jun 19.
- PMID: 34157485
- PubMed abstract
-
- The role of TP53 pathogenic variants in early-onset HER2-positive breast cancer.
- Escudeiro C, Pinto C, Vieira J, Peixoto A, Pinto P, Pinheiro M, Santos C, Guerra J, Lisboa S, Santos R, Silva J, Leal C, Coimbra N, Lopes P, Ferreira M, Sousa AB, Teixeira MR.
- Fam Cancer. 2021 Jul;20(3):173-180. doi: 10.1007/s10689-020-00212-2. Epub 2020 Oct 14.
- PMID: 33051812
- PubMed abstract
- Source abstract
-
- Targeted Next-generation Sequencing for Reliable Detection of Genetic Status in Breast Cancer.
- Tariq H, Gul A, Zubair M, Jaffer SR, Zafar N, Sadaf G.
- J Coll Physicians Surg Pak. 2021 Jul;30(7):837-840. doi: 10.29271/jcpsp.2021.07.837.
- PMID: 34271787
- PubMed abstract
-
- Ovarian metastasis from breast cancer mimicking a primary ovarian neoplasm: A case report.
- Akizawa Y, Kanno T, Horibe Y, Shimizu Y, Noguchi E, Yamamoto T, Okamoto T, Nagashima Y, Tabata T.
- Mol Clin Oncol. 2021 Jul;15(1):135. doi: 10.3892/mco.2021.2297. Epub 2021 May 17. PMID: 34055350; PMCID: PMC8145603.
- PMID: 34055350
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Clinical, Radiometabolic and Immunologic Effects of Olaparib in Locally Advanced Triple Negative Breast Cancer: The OLTRE Window of Opportunity Trial.
- Schettini F, Corona SP, Giudici F, Strina C, Sirico M, Bernocchi O, Milani M, Ziglioli N, Aguggini S, Azzini C, Barbieri G, Cervoni V, Cappelletti MR, Molteni A, Lazzari MC, Ferrero G, Ungari M, Marasco E, Bruson A, Xumerle L, Zago E, Cerra D, Loddo M, Williams GH, Paris I, Scambia G, Generali D.
- Front Oncol. 2021 Jun 28;11:686776. doi: 10.3389/fonc.2021.686776.
- PMID: 34262869
- PubMed abstract
-
- PTEN Hamartoma Tumor Syndrome/Cowden Syndrome: Genomics, Oncogenesis, and Imaging Review for Associated Lesions and Malignancy.
- Dragoo DD, Taher A, Wong VK, Elsaiey A, Consul N, Mahmoud HS, Mujtaba B, Stanietzky N, Elsayes KM.
- Cancers (Basel). 2021 Jun 22;13(13):3120. doi: 10.3390/cancers13133120.
- PMID: 34206559
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Breast cancer incidence in BRCA mutation carriers with ovarian cancer: A longitudal observational study.
- Safra T, Waissengrin B, Gerber D, Bernstein-Molho R, Klorin G, Salman L, Josephy D, Chen-Shtoyerman R, Bruchim I, Frey MK, Pothuri B, Muggia F.
- Gynecol Oncol. 2021 Jun 22:S0090-8258(21)00489-3. doi: 10.1016/j.ygyno.2021.06.009. Epub ahead of print.
- PMID: 34172288
- PubMed abstract
- Source abstract
-
- The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.
- Lakeman IMM, van den Broek AJ, Vos JAM, Barnes DR, Adlard J, Andrulis IL, Arason A, Arnold N, Arun BK, Balmaña J, Barrowdale D, Benitez J, Borg A, Caldés T, Caligo MA, Chung WK, Claes KBM; GEMO Study Collaborators; EMBRACE Collaborators, Collée JM, Couch FJ, Daly MB, Dennis J, Dhawan M, Domchek SM, Eeles R, Engel C, Evans DG, Feliubadaló L, Foretova L, Friedman E, Frost D, Ganz PA, Garber J, Gayther SA, Gerdes AM, Godwin AK, Goldgar DE, Hahnen E, Hake CR, Hamann U, Hogervorst FBL, Hooning MJ, Hopper JL, Hulick PJ, Imyanitov EN; OCGN Investigators; HEBON Investigators; KconFab Investigators, Isaacs C, Izatt L, Jakubowska A, James PA, Janavicius R, Jensen UB, Jiao Y, John EM, Joseph V, Karlan BY, Kets CM, Konstantopoulou I, Kwong A, Legrand C, Leslie G, Lesueur F, Loud JT, Lubinski J, Manoukian S, McGuffog L, Miller A, Gomes DM, Montagna M, Mouret-Fourme E, Nathanson KL, Neuhausen SL, Nevanlinna H, Yie JNY, Olah E, Olopade OI, Park SK, Parsons MT, Peterlongo P, Piedmonte M, Radice P, Rantala J, Rennert G, Risch HA, Schmutzler RK, Sharma P, Simard J, Singer CF, Stadler Z, Stoppa-Lyonnet D, Sutter C, Tan YY, Teixeira MR, Teo SH, Teulé A, Thomassen M, Thull DL, Tischkowitz M, Toland AE, Tung N, van Rensburg EJ, Vega A, Wappenschmidt B, Devilee P, van Asperen CJ, Bernstein JL, Offit K, Easton DF, Rookus MA, Chenevix-Trench G, Antoniou AC, Robson M, Schmidt MK.
- Genet Med. 2021 Jun 10. doi: 10.1038/s41436-021-01198-7. Epub ahead of print.
- PMID: 34113011
- PubMed abstract
-
- Clinical utility of testing for PALB2 and CHEK2 c.1100delC in breast and ovarian cancer.
- Woodward ER, van Veen EM, Forde C, Harkness EF, Byers HJ, Ellingford JM, Burghel GJ, Schlech H, Bowers NL, Wallace AJ, Howell SJ, Howell A, Lalloo F, Newman WG, Smith MJ, Gareth Evans D.
- Genet Med. 2021 Jun 10. doi: 10.1038/s41436-021-01234-6. Epub ahead of print.
- PMID: 34113003
- PubMed abstract
-
- Patterns and Prevalence of BRCA1 and BRCA2 Germline Mutations Among Patients with Triple-Negative Breast Cancer: Regional Perspectives.
- Abdel-Razeq H, Tamimi F, Abujamous L, Edaily S, Abunasser M, Bater R, Salama O.
- Cancer Manag Res. 2021 Jun 9;13:4597-4604. doi: 10.2147/CMAR.S316470.
- PMID: 34135636
- PubMed abstract
-
- Oncological Follow-up with 2-[18F]-FDG PET/CT in Li-Fraumeni Syndrome.
- Hernandez MA, Vega Gonzalez IF, Vélez LL, Arango CM.
- Mol Imaging Radionucl Ther. 2021 Jun 3;30(2):110-112. doi: 10.4274/mirt.galenos.2020.33255.
- PMID: 34082513
- PubMed abstract
- Source abstract
- Case report
- Free Full Text (PDF)
-
- Characterization of Benign Breast Diseases and Association With Age, Hormonal Factors, and Family History of Breast Cancer Among Women in Sweden.
- Johansson A, Christakou AE, Iftimi A, Eriksson M, Tapia J, Skoog L, Benz CC, Rodriguez-Wallberg KA, Hall P, Czene K, Lindström LS.
- JAMA Netw Open. 2021 Jun 1;4(6):e2114716. doi: 10.1001/jamanetworkopen.2021.14716.
- PMID: 34170304
- PubMed abstract
-
- DNA methylation variations in familial female and male breast cancer.
- Abeni E, Grossi I, Marchina E, Coniglio A, Incardona P, Cavalli P, Zorzi F, Chiodera PL, Paties CT, Crosatti M, De Petro G, Salvi A.
- Oncol Lett. 2021 Jun;21(6):468. doi: 10.3892/ol.2021.12729. Epub 2021 Apr 12.
- PMID: 33907578
- PubMed abstract
- Source abstract
-
- Study of the Genetic Variants in BRCA1/2 and Non-BRCA Genes in a Population-Based Cohort of 2155 Breast/Ovary Cancer Patients, Including 443 Triple-Negative Breast Cancer Patients, in Argentina.
- Solano AR, Mele PG, Jalil FS, Liria NC, Podesta EJ, Gutiérrez LG.
- Cancers (Basel). 2021 May 31;13(11):2711. doi: 10.3390/cancers13112711.
- PMID: 34072659
- PubMed abstract
- Source abstract
-
- Breast Cancer in Togolese Women: Imaging and Clinicopathological Findings.
- Darré T, Tchaou M, Djiwa T, Douaguibe B, Bassowa A, Adani-Ifé S, Amavi AK, N'Timon B, Amadou A, Simgban P, N'Bortche BK, Amégbor K, Aboubakari AS, Napo-Koura G.
- Breast Cancer (Auckl). 2021 May 30;15:11782234211020242. doi: 10.1177/11782234211020242.
- PMID: 34103923
- PubMed abstract
- Source abstract
-
- Mutations in BRCA1/2 and Other Panel Genes in Patients With Metastatic Breast Cancer -Association With Patient and Disease Characteristics and Effect on Prognosis.
- Fasching PA, Yadav S, Hu C, Wunderle M, Häberle L, Hart SN, Rübner M, Polley EC, Lee KY, Gnanaolivu RD, Hadji P, Hübner H, Tesch H, Ettl J, Overkamp F, Lux MP, Ekici AB, Volz B, Uhrig S, Lüftner D, Wallwiener M, Müller V, Belleville E, Untch M, Kolberg HC, Beckmann MW, Reis A, Hartmann A, Janni W, Wimberger P, Taran FA, Fehm TN, Wallwiener D, Brucker SY, Schneeweiss A, Hartkopf AD, Couch FJ.
- J Clin Oncol. 2021 May 20;39(15):1619-1630. doi: 10.1200/JCO.20.01200. Epub 2021 Mar 29.
- PMID: 33780288
- PubMed abstract
- Source abstract
-
- Frequency of CDH1 Germline Mutations in Non-Gastric Cancers.
- Massari G, Magnoni F, Favia G, Peradze N, Veronesi P, La Vecchia C, Corso G.
- Cancers (Basel). 2021 May 12;13(10):2321. doi: 10.3390/cancers13102321.
- PMID: 34066044
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Breast-Gynaecological & Immuno-Oncology International Cancer Conference (BGICC) Consensus and Recommendations for the Management of Triple-Negative Breast Cancer.
- Elghazaly H, Rugo HS, Azim HA, Swain SM, Arun B, Aapro M, Perez EA, Anderson BO, Penault-Llorca F, Conte P, El Saghir NS, Yip CH, Ghosn M, Poortmans P, Shehata MA, Giuliano AE, Leung JWT, Guarneri V, Gligorov J, Gulluoglu BM, Abdel Aziz H, Frolova M, Sabry M, Balch CM, Orecchia R, El-Zawahry HM, Al-Sukhun S, Abdel Karim K, Kandil A, Paltuev RM, Foheidi M, El-Shinawi M, ElMahdy M, Abulkhair O, Yang W, Aref AT, Bakkach J, Bahie Eldin N, Elghazawy H.
- Cancers (Basel). 2021 May 8;13(9):2262. doi: 10.3390/cancers13092262.
- PMID: 34066769
- PubMed abstract
- Source abstract
- Guidelines, Review
- Free PMC article
- Free Full Text
-
- [Germline and Somatic Mutations in Archived Breast Cancer Specimens of Different Subtypes].
- Abramov IS, Korneva YS, Shisterova OA, Ikonnikova AY, Emelyanova MA, Lisitsa TS, Krasnov GS, Nasedkina TV.
- Mol Biol (Mosk). 2021 May-Jun;55(3):412-421. Russian. doi: 10.31857/S0026898421030022.
- PMID: 34097676
- PubMed abstract
- Source abstract
-
- Prevalence of BRCA1 and BRCA2 mutations in Japanese patients with triple-negative breast cancer: A single institute retrospective study.
- Fujisawa F, Tamaki Y, Inoue T, Nakayama T, Yagi T, Kittaka N, Yoshinami T, Nishio M, Matsui S, Kusama H, Kamiura S.
- Mol Clin Oncol. 2021 May;14(5):96. doi: 10.3892/mco.2021.2258. Epub 2021 Mar 12.
- PMID: 33767865
- PubMed abstract
- Source abstract
-
- The ten genes for breast (and ovarian) cancer susceptibility.
- Foulkes WD.
- Nat Rev Clin Oncol. 2021 May;18(5):259-260. doi: 10.1038/s41571-021-00491-3.
- PMID: 33692540
- PubMed abstract
- Commentary
- Free Full Text
Original research:
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.
- PMID: 33471991
- PubMed abstract
- Free Full Text
Original research:
A Population-Based Study of Genes Previously Implicated in Breast Cancer.
- PMID: 33471974
- PubMed abstract
- Free Full Text
-
- CHEK2 Pathogenic Variants in Greek Breast Cancer Patients: Evidence for Strong Associations with Estrogen Receptor Positivity, Overuse of Risk-Reducing Procedures and Population Founder Effects.
- Apostolou P, Dellatola V, Papadimitriou C, Kalfakakou D, Fountzilas E, Faliakou E, Fountzilas G, Romanidou O, Konstantopoulou I, Fostira F.
- Cancers (Basel). 2021 Apr 27;13(9):2106. doi: 10.3390/cancers13092106.
- PMID: 33925588
- PubMed abstract
- Source abstract
-
- Comments on "Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns".
- Brane A, Behring M, Halilova KI, Norian L.
- Int J Cancer. 2021 Apr 22. doi: 10.1002/ijc.33605. Epub ahead of print.
- PMID: 33890298
- PubMed abstract
- Source abstract
Original research:
Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns.
- PMID: 32856720
- PubMed abstract
- Free Full Text
-
- Clinicopathologic Profile of Breast Cancer in Germline ATM and CHEK2 Mutation Carriers.
- Toss A, Tenedini E, Piombino C, Venturelli M, Marchi I, Gasparini E, Barbieri E, Razzaboni E, Domati F, Caggia F, Grandi G, Combi F, Tazzioli G, Dominici M, Tagliafico E, Cortesi L.
- Genes (Basel). 2021 Apr 21;12(5):616. doi: 10.3390/genes12050616.
- PMID: 33919281
- PubMed abstract
- Source abstract
-
- Fast Five Quiz: Breast Cancer Myths.
- Chalasani P.
- Medscape. Drugs & Diseases. 2021 Apr 20.
- Quiz
- Free Full Text
-
- Impact of clinical targeted sequencing on endocrine responsiveness in estrogen receptor-positive, HER2-negative metastatic breast cancer.
- Hagio K, Amano T, Hayashi H, Takeshita T, Oshino T, Kikuchi J, Ohhara Y, Yabe I, Kinoshita I, Nishihara H, Yamashita H.
- Sci Rep. 2021 Apr 14;11(1):8109. doi: 10.1038/s41598-021-87645-6.
- PMID: 33854152
- PubMed abstract
-
- Malignant Phyllodes Tumor of the Breast: A Practice Review.
- Fede ÂBS, Pereira Souza R, Doi M, De Brot M, Aparecida Bueno de Toledo Osorio C, Rocha Melo Gondim G, Casali-da-Rocha JC, Jbili R, Bitencourt AGV, Alves de Souza J, Caparica Bitton R, Baroni Alves Makdissi F, Moraes Sanches S.
- Clin Pract. 2021 Apr 6;11(2):205-215. doi: 10.3390/clinpract11020030.
- PMID: 33917271
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- Association of Vitamin D Receptor and Vitamin D-Binding Protein Polymorphisms with Familial Breast Cancer Prognosis in a Mono-Institutional Cohort.
- Aristarco V, Johansson H, Gandini S, Macis D, Zanzottera C, Tolva G, Feroce I, Accornero C, Bonanni B, Guerrieri-Gonzaga A, Serrano D.
- Nutrients. 2021 Apr 6;13(4):1208. doi: 10.3390/nu13041208.
- PMID: 33917614
- PubMed abstract
- Source abstract
-
- HER2-positive breast cancer in a germline BRCA1 gene large deletion carrier.
- Uchida N, Takeshita M, Suda T, Matsui Y, Yoshida M.
- Int Cancer Conf J. 2021 Apr 3;10(3):181-185. doi: 10.1007/s13691-021-00481-3.
- PMID: 34221828
- PubMed abstract
- Source abstract
-
- Breast cancer in multiple endocrine neoplasia type 1 (MEN1).
- Cheah SK, Bisambar CR, Pitfield D, Giger O, Hoopen RT, Martin JE, Clark GR, Park SM, Parkinson C, Challis BG, Casey RT.
- Endocrinol Diabetes Metab Case Rep. 2021 Apr 1;2021:EDM200196. doi: 10.1530/EDM-20-0196. Epub ahead of print.
- PMID: 33960322
- PubMed abstract
- Source abstract
- Case report, Review
- Free Full Text
-
- Tumor phenotype and concordance in synchronous bilateral breast cancer in young women.
- Pak LM, Gaither R, Rosenberg SM, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Snow C, Collins LC, King TA, Partridge AH.
- Breast Cancer Res Treat. 2021 Apr;186(3):815-821. doi: 10.1007/s10549-020-06027-0. Epub 2020 Nov 26.
- PMID: 33242164
- PubMed abstract
- Source abstract
-
- Clinical phenotypes combined with saturation genome editing identifying the pathogenicity of BRCA1 variants of uncertain significance in breast cancer.
- Wan Q, Hu L, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xu Y, Xie Y.
- Fam Cancer. 2021 Apr;20(2):85-95. doi: 10.1007/s10689-020-00202-4. Epub 2020 Aug 17.
- PMID: 32803532
- PubMed abstract
- Source abstract
-
- Clinico-radio-pathological Features and Biological Behavior of Breast Cancer in Young Indian Women: A Prospective Study.
- Sudhir R, Sannapareddy K, Potlapalli A, Penmetsa V.
- Indian J Radiol Imaging. 2021 Apr;31(2):323-332. doi: 10.1055/s-0041-1734342. Epub 2021 Jul 30.
- PMID: 34556915
- PubMed abstract
- Source abstract
-
- A male with primary accessory breast carcinoma in an axilla is strongly suspected of having hereditary breast cancer.
- Takahashi E, Terata K, Nanjo H, Ishiyama K, Hiroshima Y, Yamaguchi A, Yatsuyanagi M, Kudo C, Wakita A, Takashima S, Sato Y, Imai K, Motoyama S, Minamiya Y.
- Int Cancer Conf J. 2021 Jan 10;10(2):107-111. doi: 10.1007/s13691-020-00466-8. eCollection 2021 Apr.
- PMID: 33782642
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Clinical and Pathological Characteristics of Patients with High-Risk Breast Cancer Based on BRCA Mutation Profiles: A Retrospective Study.
- Atci MM, Geredeli Ç, Ay S, Sakin A, Ertürk B, Seçmeler S, Arici S, Çekin R, Yasar N, Can O, Cihan S, Gümüs M.
- Eur J Breast Health. 2021 Mar 31;17(2):123-127. doi: 10.4274/ejbh.galenos.2020.6346.
- PMID: 33870111
- PubMed abstract
-
- The Relationship of Mutation Carriage of BRCA1/2 and Family History in Triple-Negative Breast Cancer: Experience from a Diagnostic Center in Turkey.
- Duzkale N, Kandemir O.
- Eur J Breast Health. 2021 Mar 31;17(2):137-144. doi: 10.4274/ejbh.galenos.2020.5909.
- PMID: 33870113
- PubMed abstract
-
- What’s Autism Got To Do With It?
- [No author given]
- My Gene Counsel. Genetic Journal. 2021 Mar 27.
- Blog post
- Free Full Text
-
- Investigation of The Relationship of TNFRSF11A Gene Polymorphisms with Breast Cancer Development and Metastasis Risk in Patients with BRCA1 Or BRCA2 Pathogenic Variants Living in The Trakya Region of Turkey.
- Özdemir K, Gürkan H, Demir S, Atli E, Özen Y, Sezer A, Tunçbilek N, Çicin I.
- Balkan J Med Genet. 2021 Mar 23;23(2):49-58. doi: 10.2478/bjmg-2020-0016. eCollection 2020 Nov.
- PMID: 33816072
- PubMed abstract
- Source abstract
-
- Novel and recurrent BRCA1/BRCA2 germline mutations in patients with breast/ovarian cancer: a series from the south of Tunisia.
- Ben Ayed-Guerfali D, Ben Kridis-Rejab W, Ammous-Boukhris N, Ayadi W, Charfi S, Khanfir A, Sellami-Boudawara T, Frikha M, Daoud J, Mokdad-Gargouri R.
- J Transl Med. 2021 Mar 16;19(1):108. doi: 10.1186/s12967-021-02772-y.
- PMID: 33726785
- PubMed abstract
-
- Breast Cancer Brain Metastasis-Overview of Disease State, Treatment Options and Future Perspectives.
- Watase C, Shiino S, Shimoi T, Noguchi E, Kaneda T, Yamamoto Y, Yonemori K, Takayama S, Suto A.
- Cancers (Basel). 2021 Mar 3;13(5):1078. doi: 10.3390/cancers13051078.
- PMID: 33802424
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- Next Generation Sequencing-Based Germline Panel Testing for Breast and Ovarian Cancers in Pakistan.
- Tariq H, Gul A, Khadim T, Ud-Din H, Tipu HN, Asif M, Ahmed R.
- Asian Pac J Cancer Prev. 2021 Mar 1;22(3):719-724. doi: 10.31557/APJCP.2021.22.3.719.
- PMID: 33773534
- PubMed abstract
- Source abstract
-
- Gene Sequencing for Pathogenic Variants Among Adults With Breast and Ovarian Cancer in the Caribbean.
- George SHL, Donenberg T, Alexis C, DeGennaro V Jr, Dyer H, Yin S, Ali J, Butler R, Chin SN, Curling D, Lowe D, Lunn J, Turnquest T, Wharfe G, Cerbon D, Barreto-Coelho P, Schlumbrecht MP, Akbari MR, Narod SA, Hurley JE.
- JAMA Netw Open. 2021 Mar 1;4(3):e210307. doi: 10.1001/jamanetworkopen.2021.0307.
- PMID: 33646313
- PubMed abstract
-
- Prevalence of BRCA1 and BRCA2 genes promoter hypermethylation in breast cancer tissue.
- Lobanova OE, Rossokha ZI, Medvedieva NL, Cheshuk VE, Vereshchako RI, Vershyhora VO, Fishchuk LY, Zakhartseva LM, Gorovenko NG.
- Exp Oncol. 2021 Mar;43(1):56-60. doi: 10.32471/exp-oncology.2312-8852.vol-43-no-1.15703.
- PMID: 33785722
- PubMed abstract
-
- The relationship between BRCA-associated breast cancer and age factors: an analysis of the Japanese HBOC consortium database.
- Okano M, Nomizu T, Tachibana K, Nagatsuka M, Matsuzaki M, Katagata N, Ohtake T, Yokoyama S, Arai M, Nakamura S.
- J Hum Genet. 2021 Mar;66(3):307-314. doi: 10.1038/s10038-020-00849-y. Epub 2020 Oct 12.
- PMID: 33046835
- PubMed abstract
-
- Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns.
- Ugalde-Morales E, Grassmann F, Humphreys K, Li J, Eriksson M, Tobin NP, Borg Å, Vallon-Christersson J, Hall P, Czene K.
- Int J Cancer. 2021 Feb 15;148(4):884-894. doi: 10.1002/ijc.33270. Epub 2020 Sep 5.
- PMID: 32856720
- PubMed abstract
- Source abstract
Letter, Commentary:
Comments on "Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns".
- PMID: 33890298
- PubMed abstract
- Source abstract
-
- The Rare Diagnosis of Synchronous Breast and Colonic Cancers: A Case Report and Review of Literature.
- Asaad A, Barron M, Rasheed N, Idaewor P, Saad Abdalla Al-Zawi A.
- Cureus. 2021 Feb 12;13(2):e13314. doi: 10.7759/cureus.13314.
- PMID: 33738159
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants.
- Lambertini M, Ceppi M, Hamy AS, Caron O, Poorvu PD, Carrasco E, Grinshpun A, Punie K, Rousset-Jablonski C, Ferrari A, Paluch-Shimon S, Toss A, Senechal C, Puglisi F, Pogoda K, Pérez-Fidalgo JA, De Marchis L, Ponzone R, Livraghi L, Estevez-Diz MDP, Villarreal-Garza C, Dieci MV, Clatot F, Duhoux FP, Graffeo R, Teixeira L, Córdoba O, Sonnenblick A, Ferreira AR, Partridge AH, Di Meglio A, Saule C, Peccatori FA, Bruzzone M, t'Kint de Roodenbeke MD, Ameye L, Balmaña J, Del Mastro L, Azim HA Jr.
- NPJ Breast Cancer. 2021 Feb 12;7(1):16. doi: 10.1038/s41523-021-00224-w.
- PMID: 33579978
- PubMed abstract
-
- Molecular analyses of triple-negative breast cancer in the young and elderly.
- Aine M, Boyaci C, Hartman J, Häkkinen J, Mitra S, Campos AB, Nimeus E, Ehinger A, Vallon-Christersson J, Borg Å, Staaf J.
- Breast Cancer Res. 2021 Feb 10;23(1):20. doi: 10.1186/s13058-021-01392-0.
- PMID: 33568222
- PubMed abstract
-
- Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.
- Breast Cancer Association Consortium, Dorling L, Carvalho S, Allen J, González-Neira A, Luccarini C, Wahlström C, Pooley KA, Parsons MT, Fortuno C, Wang Q, Bolla MK, Dennis J, Keeman R, Alonso MR, Álvarez N, Herraez B, Fernandez V, Núñez-Torres R, Osorio A, Valcich J, Li M, Törngren T, Harrington PA, Baynes C, Conroy DM, Decker B, Fachal L, Mavaddat N, Ahearn T, Aittomäki K, Antonenkova NN, Arnold N, Arveux P, Ausems MGEM, Auvinen P, Becher H, Beckmann MW, Behrens S, Bermisheva M, Bialkowska K, Blomqvist C, Bogdanova NV, Bogdanova-Markov N, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H, Bremer M, Briceno I, Brüning T, Burwinkel B, Cameron DA, Camp NJ, Campbell A, Carracedo A, Castelao JE, Cessna MH, Chanock SJ, Christiansen H, Collée JM, Cordina-Duverger E, Cornelissen S, Czene K, Dörk T, Ekici AB, Engel C, Eriksson M, Fasching PA, Figueroa J, Flyger H, Försti A, Gabrielson M, Gago-Dominguez M, Georgoulias V, Gil F, Giles GG, Glendon G, Garcia EBG, Alnæs GIG, Guénel P, Hadjisavvas A, Haeberle L, Hahnen E, Hall P, Hamann U, Harkness EF, Hartikainen JM, Hartman M, He W, Heemskerk-Gerritsen BAM, Hillemanns P, Hogervorst FBL, Hollestelle A, Ho WK, Hooning MJ, Howell A, Humphreys K, Idris F, Jakubowska A, Jung A, Kapoor PM, Kerin MJ, Khusnutdinova E, Kim SW, Ko YD, Kosma VM, Kristensen VN, Kyriacou K, Lakeman IMM, Lee JW, Lee MH, Li J, Lindblom A, Lo WY, Loizidou MA, Lophatananon A, Lubinski J, MacInnis RJ, Madsen MJ, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martinez ME, Maurer T, Mavroudis D, McLean C, Meindl A, Mensenkamp AR, Michailidou K, Miller N, Mohd Taib NA, Muir K, Mulligan AM, Nevanlinna H, Newman WG, Nordestgaard BG, Ng PS, Oosterwijk JC, Park SK, Park-Simon TW, Perez JIA, Peterlongo P, Porteous DJ, Prajzendanc K, Prokofyeva D, Radice P, Rashid MU, Rhenius V, Rookus MA, Rüdiger T, Saloustros E, Sawyer EJ, Schmutzler RK, Schneeweiss A, Schürmann P, Shah M, Sohn C, Southey MC, Surowy H, Suvanto M, Thanasitthichai S, Tomlinson I, Torres D, Truong T, Tzardi M, Valova Y, van Asperen CJ, Van Dam RM, van den Ouweland AMW, van der Kolk LE, van Veen EM, Wendt C, Williams JA, Yang XR, Yoon SY, Zamora MP, Evans DG, de la Hoya M, Simard J, Antoniou AC, Borg Å, Andrulis IL, Chang-Claude J, García-Closas M, Chenevix-Trench G, Milne RL, Pharoah PDP, Schmidt MK, Spurdle AB, Vreeswijk MPG, Benitez J, Dunning AM, Kvist A, Teo SH, Devilee P, Easton DF.
- N Engl J Med. 2021 Feb 4;384(5):428-439. doi: 10.1056/NEJMoa1913948. Epub 2021 Jan 20.
- PMID: 33471991
- PubMed abstract
•• Editorial:
Which Genes for Hereditary Breast Cancer?
- PMID: 33471975
- PubMed abstract
- Source abstract
•• Commentary:
The ten genes for breast (and ovarian) cancer susceptibility.
- PMID: 33692540
- PubMed abstract
- Free Full Text
•• Commentary:
The other side of the coin: dissecting molecular mechanisms behind hereditary breast cancer in search of therapeutic opportunities.
- PMID: 33993096
- PubMed abstract
- Free Full Text
•• Press: Breast Cancer Risk Gene Associations Refined in Large-Scale Studies. (Precision Oncology News)
•• Press: New Breast Cancer Mutation Findings Could Change Risk Management. (Medscape)
-
- A Population-Based Study of Genes Previously Implicated in Breast Cancer.
- Hu C, Hart SN, Gnanaolivu R, Huang H, Lee KY, Na J, Gao C, Lilyquist J, Yadav S, Boddicker NJ, Samara R, Klebba J, Ambrosone CB, Anton-Culver H, Auer P, Bandera EV, Bernstein L, Bertrand KA, Burnside ES, Carter BD, Eliassen H, Gapstur SM, Gaudet M, Haiman C, Hodge JM, Hunter DJ, Jacobs EJ, John EM, Kooperberg C, Kurian AW, Le Marchand L, Lindstroem S, Lindstrom T, Ma H, Neuhausen S, Newcomb PA, O'Brien KM, Olson JE, Ong IM, Pal T, Palmer JR, Patel AV, Reid S, Rosenberg L, Sandler DP, Scott C, Tamimi R, Taylor JA, Trentham-Dietz A, Vachon CM, Weinberg C, Yao S, Ziogas A, Weitzel JN, Goldgar DE, Domchek SM, Nathanson KL, Kraft P, Polley EC, Couch FJ.
- N Engl J Med. 2021 Feb 4;384(5):440-451. doi: 10.1056/NEJMoa2005936. Epub 2021 Jan 20.
- PMID: 33471974
- PubMed abstract
•• Editorial:
Which Genes for Hereditary Breast Cancer?
- PMID: 33471975
- PubMed abstract
- Source abstract
•• Commentary:
The ten genes for breast (and ovarian) cancer susceptibility.
- PMID: 33692540
- PubMed abstract
- Free Full Text
•• Commentary:
The other side of the coin: dissecting molecular mechanisms behind hereditary breast cancer in search of therapeutic opportunities.
- PMID: 33993096
- PubMed abstract
- Free Full Text
•• Press: Breast Cancer Risk Gene Associations Refined in Large-Scale Studies. (Precision Oncology News)
•• Press: New Breast Cancer Mutation Findings Could Change Risk Management. (Medscape)
-
- Under-ascertainment of breast cancer susceptibility gene carriers in a cohort of New Zealand female breast cancer patients.
- Lattimore V, Parsons MT, Spurdle AB, Pearson J, Lehnert K, Sullivan J, Lintott C, Bawden S, Morrin H, Robinson B, Walker L.
- Breast Cancer Res Treat. 2021 Feb;185(3):583-590. doi: 10.1007/s10549-020-05986-8. Epub 2020 Oct 28.
- PMID: 33113089
- PubMed abstract
-
- Effects of Germline Pathogenic Variants, Cancer Subtypes, Tumor-related Characteristics, and Pregnancy-associated Diagnosis on Outcomes.
- Tsai ML, Knaack M, Martone P, Krueger J, Baldinger SR, Lillemoe TJ, Susnik B, Grimm E, Olet S, Rueth N, Swenson KK.
- Clin Breast Cancer. 2021 Feb;21(1):47-56. doi: 10.1016/j.clbc.2020.07.003. Epub 2020 Jul 9.
- PMID: 32739136
- PubMed abstract
- Source abstract
-
- Androgen receptor expression and outcome of neoadjuvant chemotherapy in triple-negative breast cancer.
- Di Leone A, Fragomeni SM, Scardina L, Ionta L, Mulè A, Magno S, Terribile D, Masetti R, Franceschini G.
- Eur Rev Med Pharmacol Sci. 2021 Feb;25(4):1910-1915. doi: 10.26355/eurrev_202102_25087.
- PMID: 33660830
- PubMed abstract
- Source abstract
-
- Comprehensive Genomic Profiling-Guided Niraparib Treatment of Triple-Negative Breast Cancer in a Patient With Extensive Brain Metastasis: Case Report and Literature Review.
- Lam TC.
- J Immunother Precis Oncol. 2021 Jan 29 [eCollection 2021 Feb];4(1):16-20. doi: 10.36401/JIPO-20-24.
- PMID: 35664827
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Germline pathogenic variants in the Ataxia Telangiectasia Mutated (ATM) gene are associated with high and moderate risks for multiple cancers.
- Hall MJ, Bernhisel R, Hughes E, Larson K, Rosenthal ET, Singh NA, Lancaster JM, Kurian AW.
- Cancer Prev Res (Phila). 2021 Jan 28:canprevres.0448.2020. doi: 10.1158/1940-6207.CAPR-20-0448. Epub ahead of print.
- PMID: 33509806
- PubMed abstract
- Source abstract
-
- BARD1 Pathogenic Variants are Associated with Triple-Negative Breast Cancer in a Spanish Hereditary Breast and Ovarian Cancer Cohort.
- Rofes P, Del Valle J, Torres-Esquius S, Feliubadaló L, Stradella A, Moreno-Cabrera JM, López-Doriga A, Munté E, De Cid R, Campos O, Cuesta R, Teulé Á, Grau È, Sanz J, Capellá G, Díez O, Brunet J, Balmaña J, Lázaro C.
- Genes (Basel). 2021 Jan 23;12(2):150. doi: 10.3390/genes12020150.
- PMID: 33498765
- PubMed abstract
- Source abstract
-
- PDGFRß is an essential therapeutic target for BRCA1-deficient mammary tumors.
- Bai F, Liu S, Liu X, Hollern DP, Scott A, Wang C, Zhang L, Fan C, Fu L, Perou CM, Zhu WG, Pei XH.
- Breast Cancer Res. 2021 Jan 21;23(1):10. doi: 10.1186/s13058-021-01387-x.
- PMID: 33478572
- PubMed abstract
-
- Inherited predisposition to breast cancer in the Carolina Breast Cancer Study.
- Walsh T, Gulsuner S, Lee MK, Troester MA, Olshan AF, Earp HS, Perou CM, King MC.
- NPJ Breast Cancer. 2021 Jan 21;7(1):6. doi: 10.1038/s41523-020-00214-4.
- PMID: 33479248
- PubMed abstract
-
- Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort.
- Liu Y, Wang H, Wang X, Liu J, Li J, Wang X, Zhang Y, Bai Z, Zhou Q, Wu Y, Shen Y, Weng X, Liu F, Guo J, Di L, Gires O, Zhang Z, Chen Y, Wang H.
- J Hematol Oncol. 2021 Jan 18;14(1):18. doi: 10.1186/s13045-020-01010-0.
- PMID: 33461583
- PubMed abstract
-
- Insights Into the Impacts of BRCA Mutations on Clinicopathology and Management of Early-Onset Triple-Negative Breast Cancer.
- Ye F, He M, Huang L, Lang G, Hu X, Shao Z, Di G, Cao A.
- Front Oncol. 2021 Jan 11;10:574813. doi: 10.3389/fonc.2020.574813.
- PMID: 33505905
- PubMed abstract
-
- Metaplastic carcinoma of the breast and BRCA1 germline mutation: a case report and review.
- Yamashita M, Kamei Y, Murakami A, Ozaki E, Okujima K, Takemoto K, Takaoka M, Tsukamoto D, Kusakabe E, Shidahara T, Noda H, Aoki R, Taguchi K, Nishiyama K, Eguchi M, Takada Y.
- Hered Cancer Clin Pract. 2021 Jan 6;19(1):3. doi: 10.1186/s13053-020-00162-x.
- PMID: 33407746
- PubMed abstract
- Free Full Text
-
- Triple-Negative Breast Cancer: Breast Tumors With an Identity Crisis.
- Nunnery SE, Mayer IA, Balko JM.
- Cancer J. 2021 Jan-Feb 01;27(1):2-7. doi: 10.1097/PPO.0000000000000494.
- PMID: 33475287
- PubMed abstract
- Source abstract
-
- The clinicopathological and MRI features of patients with BRCA1/2 mutations in familial breast cancer.
- You C, Xiao Q, Zhu X, Sun Y, Di G, Liu G, Hou Y, Chen C, Wu J, Shao Z, Gu Y, Hu Z.
- Gland Surg. 2021 Jan;10(1):262-272. doi: 10.21037/gs-20-596.
- PMID: 33633982
- PubMed abstract
-
- Frequency of high-risk hormone receptor-positive breast cancer patients was much higher in Japanese breast cancer patients with germline BRCA1/2 mutations than in sporadic breast cancer patients.
- Ide Y, Liu L, Miura S, Inuzuka M, Akashi-Tanaka S, Sawada T, Nakamura S.
- Breast J. 2020 Dec 30. doi: 10.1111/tbj.14150. Epub ahead of print.
- PMID: 33378795
- PubMed abstract
-
- Novel BRCA2 c.8434_8435insTT (p. Gly2812Valfs*10) mutation in a family with multiple hematologic malignancies and solid tumors.
- Yin F, Kosewski B, Baer MR.
- Leuk Lymphoma. 2020 Dec 21:1-5. doi: 10.1080/10428194.2020.1861269. Epub ahead of print.
- PMID: 33345658
- PubMed abstract
- Source abstract
-
- Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients.
- Rashid MU, Muhammad N, Khan FA, Shehzad U, Naeemi H, Malkani N, Hamann U.
- Hered Cancer Clin Pract. 2020 Dec 20;18(1):25. doi: 10.1186/s13053-020-00159-6.
- PMID: 33342430
- PubMed abstract
-
- BRCA1/2 pathogenic variants in triple-negative versus luminal-like breast cancers: genotype-phenotype correlation in a cohort of 531 patients.
- Incorvaia L, Fanale D, Bono M, Calò V, Fiorino A, Brando C, Corsini LR, Cutaia S, Cancelliere D, Pivetti A, Filorizzo C, La Mantia M, Barraco N, Cusenza S, Badalamenti G, Russo A, Bazan V.
- Ther Adv Med Oncol. 2020 Dec 16;12:1758835920975326. doi: 10.1177/1758835920975326.
- PMID: 33403015
- PubMed abstract
- Source abstract
-
- Germline TP53 Testing in Breast Cancers: Why, When and How?
- Evans DG, Woodward ER, Bajalica-Lagercrantz S, Oliveira C, Frebourg T.
- Cancers (Basel). 2020 Dec 14;12(12):3762. doi: 10.3390/cancers12123762.
- PMID: 33327514
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Synchronous and Metachronous Breast and Ovarian Cancer: Experience From Two Large Cancer Center.
- Tasca G, Dieci MV, Baretta Z, Faggioni G, Montagna M, Nicoletto MO, Peccatori FA, Guarneri V, Colombo N.
- Front Oncol. 2020 Dec 14;10:608783. doi: 10.3389/fonc.2020.608783.
- PMID: 33381461
- PubMed abstract
-
- Hereditary Diffuse Gastric Cancer: A Comparative Cohort Study According to Pathogenic Variant Status.
- Marwitz T, Hüneburg R, Spier I, Lau JF, Kristiansen G, Lingohr P, Kalff JC, Aretz S, Nattermann J, Strassburg CP.
- Cancers (Basel). 2020 Dec 11;12(12):E3726. doi: 10.3390/cancers12123726.
- PMID: 33322525
- PubMed abstract
- Source abstract
-
- Impact of BRCA Mutation Status on Tumor Infiltrating Lymphocytes (TILs), Response to Treatment, and Prognosis in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.
- Grandal B, Evrevin C, Laas E, Jardin I, Rozette S, Laot L, Dumas E, Coussy F, Pierga JY, Brain E, Saule C, Stoppa-Lyonnet D, Frank S, Sénéchal C, Lae M, De Croze D, Bataillon G, Guerin J, Reyal F, Hamy AS.
- Cancers (Basel). 2020 Dec 8;12(12):3681. doi: 10.3390/cancers12123681.
- PMID: 33302444
- PubMed abstract
- Source abstract
-
- Heritability of Low ER Staining/HER2-Breast Tumors: Are We Missing an Opportunity for Germline Testing?
- Lovejoy LA, Turner CE, Wells JM, Shriver CD, Ellsworth RE.
- Genes (Basel). 2020 Dec 8;11(12):E1469. doi: 10.3390/genes11121469.
- PMID: 33302456
- PubMed abstract
- Source abstract
-
- Exome sequencing identifies a recurrent variant in SERPINA3 associating with hereditary susceptibility to breast cancer.
- Koivuluoma S, Tervasmäki A, Kauppila S, Winqvist R, Kumpula T, Kuismin O, Moilanen J, Pylkäs K.
- Eur J Cancer. 2020 Dec 3;143:46-51. doi: 10.1016/j.ejca.2020.10.033. Epub ahead of print.
- PMID: 33279852
- PubMed abstract
-
- BRCAness as a prognostic indicator in patients with early breast cancer.
- Liu L, Matsunaga Y, Tsurutani J, Akashi-Tanaka S, Masuda H, Ide Y, Hashimoto R, Inuzuka M, Watanabe C, Taruno K, Sawada T, Okuyama H, Ata A, Kuwayama T, Nakayama S, Tonouchi Y, Nakamura S.
- Sci Rep. 2020 Dec 3;10(1):21173. doi: 10.1038/s41598-020-78016-8.
- PMID: 33273622
- PubMed abstract
-
- Hereditary Diffuse Gastric Cancer: Approaches to Screening, Surveillance, and Treatment.
- Pilonis ND, Tischkowitz M, Fitzgerald RC, di Pietro M.
- Annu Rev Med. 2020 Nov 20. doi: 10.1146/annurev-med-051019-103216. Epub ahead of print.
- PMID: 33217247
- PubMed abstract
- Source abstract
-
- Early-onset malignant phyllodes breast tumor in a patient with germline pathogenic variants in NF1 and BRCA1 genes.
- Gensini F, Sestini R, De Luca A, Pinna V, Daniele P, Orzalesi L, Petrella MC, Porfirio B, Papi L.
- Fam Cancer. 2020 Nov 19. doi: 10.1007/s10689-020-00217-x. Epub ahead of print.
- PMID: 33210232
- PubMed abstract
- Source abstract
-
- Germline BRCA-mutated metastatic breast cancer with positive hormone receptor.
- Palleschi M, Iaia ML, Casadei C.
- Breast Cancer Res Treat. 2020 Nov 10. doi: 10.1007/s10549-020-06010-9. Epub ahead of print.
- PMID: 33170437
- PubMed abstract
- Source abstract
Original research:
Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study.
- PMID: 32771088
- PubMed abstract
- Source abstract
-
- Risk of invasive breast cancer in relatives of patients with breast carcinoma in situ: a prospective cohort study.
- Mukama T, Fallah M, Brenner H, Xu X, Sundquist K, Sundquist J, Kharazmi E.
- BMC Med. 2020 Nov 5;18(1):295. doi: 10.1186/s12916-020-01772-x.
- PMID: 33148280
- PubMed abstract
-
- Isoflavone intake on the risk of overall breast cancer and molecular subtypes in women at high risk for hereditary breast cancer.
- Sim EJ, Ko KP, Ahn C, Park SM, Surh YJ, An S, Kim SW, Lee MH, Lee JW, Lee JE, Kim KS, Yom CK, Kim HA, Park SK.
- Breast Cancer Res Treat. 2020 Nov;184(2):615-626. doi: 10.1007/s10549-020-05875-0. Epub 2020 Oct 17.
- PMID: 33068197
- PubMed abstract
- Source abstract
-
- Hereditary diffuse gastric cancer therapeutic roadmap: current and novel approaches in a nutshell.
- El Rami FE, Barsoumian HB, Khneizer GW.
- Ther Adv Med Oncol. 2020 Oct 31;12:1758835920967238. doi: 10.1177/1758835920967238.
- PMID: 33193828
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Prevalence of germline BRCA mutations in HER2-negative metastatic breast cancer: global results from the real-world, observational BREAKOUT study.
- O'Shaughnessy J, Brezden-Masley C, Cazzaniga M, Dalvi T, Walker G, Bennett J, Ohsumi S.
- Breast Cancer Res. 2020 Oct 27;22(1):114. doi: 10.1186/s13058-020-01349-9.
- PMID: 33109210
- PubMed abstract
-
- NGS Panel Testing of Triple-Negative Breast Cancer Patients in Cyprus: A Study of BRCA-Negative Cases.
- Zanti M, Loizidou MA, Michailidou K, Pirpa P, Machattou C, Marcou Y, Kyriakou F, Kakouri E, Tanteles GA, Spanou E, Spyrou GM, Kyriacou K, Hadjisavvas A.
- Cancers (Basel). 2020 Oct 27;12(11):3140. doi: 10.3390/cancers12113140.
- PMID: 33120919
- PubMed abstract
- Source abstract
-
- BARD1 and Breast Cancer: The Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women.
- Sniadecki M, Brzezinski M, Darecka K, Klasa-Mazurkiewicz D, Poniewierza P, Krzeszowiec M, Kmiec N, Wydra D.
- Genes (Basel). 2020 Oct 24;11(11):1251. doi: 10.3390/genes11111251.
- PMID: 33114377
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Comparison of interval breast cancers with 2D digital mammography versus 3D digital breast tomosynthesis in a large community-based practice.
- Winter AM, Kazmi S, Hardy AK, Bennett DL.
- Breast J. 2020 Oct 16. doi: 10.1111/tbj.14047. Epub ahead of print.
- PMID: 33064341
- PubMed abstract
- Source abstract
-
- The abundance of the long intergenic non-coding RNA 01087 differentiates between luminal and triple-negative breast cancers and predicts patient outcome.
- De Palma FDE, Monaco VD, Pol JG, Kremer M, D'Argenio V, Stoll G, Montanaro D, Uszczynska-Ratajczak B, Klein CC, Vlasova A, Botti G, D'Aiuto M, Baldi A, Guigó R, Kroemer G, Maiuri MC, Salvatore F.
- Pharmacol Res. 2020 Oct 14:105249. doi: 10.1016/j.phrs.2020.105249. Epub ahead of print.
- PMID: 33068730
- PubMed abstract
-
- Bilateral Disease Common Among Slovenian CHEK2-Positive Breast Cancer Patients.
- Nizic-Kos T, Krajc M, Blatnik A, Stegel V, Skerl P, Novakovic S, Gazic B, Besic N.
- Ann Surg Oncol. 2020 Oct 8. doi: 10.1245/s10434-020-09178-y. Epub ahead of print.
- PMID: 33030641
- PubMed abstract
- Source abstract
-
- Germline BRCA Mutation and Clinical Outcomes in Breast Cancer Patients Focusing on Survival and Failure Patterns: A Long-Term Follow-Up Study of Koreans.
- Kim H, Choi DH, Park W.
- Medicina (Kaunas). 2020 Oct 1;56(10):E514. doi: 10.3390/medicina56100514.
- PMID: 33019612
- PubMed abstract
- Source abstract
-
- Breast Cancer Surveillance Following Ovarian Cancer in BRCA Mutation Carriers.
- Fong A, Cass I, John C, Gillen J, Moore KM, Gangi A, Walsh C, Li AJ, Rimel BJ, Karlan BY, Amersi F.
- Am Surg. 2020 Oct;86(10):1243-1247. doi: 10.1177/0003134820964208. Epub 2020 Oct 26.
- PMID: 33106023
- PubMed abstract
- Source abstract
-
- Identifying germline APOBEC3B deletion and immune phenotype in Korean patients with operable breast cancer.
- Kim SH, Ahn S, Suh KJ, Kim YJ, Park SY, Kang E, Kim EK, Kim IA, Chae S, Choi M, Kim JH.
- Breast Cancer Res Treat. 2020 Oct;183(3):697-704. doi: 10.1007/s10549-020-05811-2. Epub 2020 Jul 26.
- PMID: 32715441
- PubMed abstract
- Source abstract
-
- Breast cancer screening in women at high risk of hereditary breast cancer: an Australian experience.
- Bennett I, Tourani S, Cockburn L, Reasbeck J, Grobbelaar N, Dann S, Patrikios P, Brazier J.
- ANZ J Surg. 2020 Sep 30. doi: 10.1111/ans.16320. Epub ahead of print.
- PMID: 33000553
- PubMed abstract
- Source abstract
-
- Pathology of Hereditary Breast and Ovarian Cancer.
- Hodgson A, Turashvili G.
- Front Oncol. 2020 Sep 29;10:531790. doi: 10.3389/fonc.2020.531790.
- PMID: 33117676
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk.
- Kramer I, Hooning MJ, Mavaddat N, Hauptmann M, Keeman R, Steyerberg EW, Giardiello D, Antoniou AC, Pharoah PDP, Canisius S, Abu-Ful Z, Andrulis IL, Anton-Culver H, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Bremer M, Brucker SY, Burwinkel B, Castelao JE, Chan TL, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Choi JY, Clarke CL; NBCS Collaborators, Collée JM, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dörk T, Dos-Santos-Silva I, Dunning AM, Dwek M, Eccles DM, Evans DG, Fasching PA, Flyger H, Gago-Dominguez M, García-Closas M, García-Sáenz JA, Giles GG, Goldgar DE, González-Neira A, Haiman CA, Håkansson N, Hamann U, Hartman M, Heemskerk-Gerritsen BAM, Hollestelle A, Hopper JL, Hou MF, Howell A; ABCTB Investigators; kConFab Investigators, Ito H, Jakimovska M, Jakubowska A, Janni W, John EM, Jung A, Kang D, Kets CM, Khusnutdinova E, Ko YD, Kristensen VN, Kurian AW, Kwong A, Lambrechts D, Le Marchand L, Li J, Lindblom A, Lubinski J, Mannermaa A, Manoochehri M, Margolin S, Matsuo K, Mavroudis D, Meindl A, Milne RL, Mulligan AM, Muranen TA, Neuhausen SL, Nevanlinna H, Newman WG, Olshan AF, Olson JE, Olsson H, Park-Simon TW, Peto J, Petridis C, Plaseska-Karanfilska D, Presneau N, Pylkäs K, Radice P, Rennert G, Romero A, Roylance R, Saloustros E, Sawyer EJ, Schmutzler RK, Schwentner L, Scott C, See MH, Shah M, Shen CY, Shu XO, Siesling S, Slager S, Sohn C, Southey MC, Spinelli JJ, Stone J, Tapper WJ, Tengström M, Teo SH, Terry MB, Tollenaar RAEM, Tomlinson I, Troester MA, Vachon CM, van Ongeval C, van Veen EM, Winqvist R, Wolk A, Zheng W, Ziogas A, Easton DF, Hall P, Schmidt MK.
- Am J Hum Genet. 2020 Sep 28:S0002-9297(20)30321-9. doi: 10.1016/j.ajhg.2020.09.001. Epub ahead of print.
- PMID: 33022221
- PubMed abstract
- Source abstract
-
- Screening of germline mutations in young Rwandan patients with breast cancers.
- Uyisenga JP, Segers K, Lumaka AZ, Mugenzi P, Fasquelle C, Boujemila B, Josse C, Mutesa L, Bours V.
- Mol Genet Genomic Med. 2020 Sep 22:e1500. doi: 10.1002/mgg3.1500. Epub ahead of print.
- PMID: 32959997
- PubMed abstract
- Source abstract
-
- Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status.
- Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, Johannsson OT, Ejlertsen B, Sønderstrup IMH, Hovig E, Lænkholm AV, Hansen TVO, Olafsdottir GH, Rossing M, Jonasson JG, Sigurdsson S, Loman N, Nilsson MP, Narod SA, Tryggvadottir L.
- Br J Cancer. 2020 Sep 17. doi: 10.1038/s41416-020-01056-4. Epub ahead of print.
- PMID: 32939053
- PubMed abstract
- Source abstract
-
- Significance of E-cadherin Gene Mutations in Patients With Hereditary Diffuse Gastric Cancer Syndrome: A Systematic Review.
- Goud HK, Mehkari Z, Mohammed L, Javed M, Althwanay A, Ahsan F, Oliveri F, Rutkofsky IH.
- Cureus. 2020 Sep 12;12(9):e10406. doi: 10.7759/cureus.10406.
- PMID: 33062523
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- First report of a Mexican family with mutation in the CDH1 gene.
- Martínez Valenzuela C, Castelán-Maldonado EE, Carvajal-Zarrabal O, Calderón-Garcidueñas AL.
- Mol Genet Genomic Med. 2020 Sep 4:e1208. doi: 10.1002/mgg3.1208. Epub ahead of print.
- PMID: 32886433
- PubMed abstract
- Source abstract
- Case report
- Free Full Text
-
- Risk factors for inflammatory and non-inflammatory breast cancer in North Africa.
- Schairer C, Hablas A, Eldein IAS, Gaafar R, Rais H, Mezlini A, Ayed FB, Ayoub WB, Benider A, Tahri A, Khouchani M, Aboulazm D, Karkouri M, Eissa S, Bastawisy AE, Yehia M, Gadalla SM, Swain SM, Merajver SD, Brown LM, Pfeiffer RM, Soliman AS.
- Breast Cancer Res Treat. 2020 Sep 2. doi: 10.1007/s10549-020-05864-3. Epub ahead of print.
- PMID: 32876910
- PubMed abstract
- Source abstract
-
- Characteristics associated with inflammatory breast cancer (IBC): An epidemiologic study from a dedicated IBC program.
- White RE, Warren L, Nakhlis F, Rosenbluth J, Bellon J, Block C, Overmoyer B.
- Breast J. 2020 Sep 1. doi: 10.1111/tbj.14030. Epub ahead of print.
- PMID: 32875655
- PubMed abstract
- Source abstract
-
- Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer.
- Huang RSP, Li X, Haberberger J, Sokol E, Severson E, Duncan DL, Hemmerich A, Edgerly C, Ferguson NL, Williams E, Elvin J, Vergilio JA, Killian JK, Lin D, Hiemenz M, Xiao J, McEwan D, Holmes O, Danziger N, Erlich R, Frampton G, Cohen MB, McGregor K, Reddy P, Cardeiro D, Anhorn R, Venstrom PJ, Alexander B, Brown C, Pusztai L, Ross JS, Ramkissoon SH.
- Oncologist. 2020 Sep 1. doi: 10.1634/theoncologist.2020-0449. Epub ahead of print.
- PMID: 32869930
- PubMed abstract
- Source abstract
-
- Male Breast Cancer in Togo: Imaging and Clinicopathological Findings.
- Darre T, Tchaou M, Djiwa T, Simgban P, Amavi AK, N'Timon B, Amadou A, Bombonne M, Sama B, Amégbor K, Napo-Koura G.
- Int J Breast Cancer. 2020 Aug 31;2020:3056067. doi: 10.1155/2020/3056067.
- PMID: 32934847
- PubMed abstract
-
- Detection of Germline Mutations in a Cohort of 139 Patients with Bilateral Breast Cancer by Multi-Gene Panel Testing: Impact of Pathogenic Variants in Other Genes beyond BRCA1/2.
- Fanale D, Incorvaia L, Filorizzo C, Bono M, Fiorino A, Calò V, Brando C, Corsini LR, Barraco N, Badalamenti G, Russo A, Bazan V.
- Cancers (Basel). 2020 Aug 25;12(9):2415. doi: 10.3390/cancers12092415.
- PMID: 32854451
- PubMed abstract
- Source abstract
-
- Identification of Recurrent Variants in BRCA1 and BRCA2 across Multiple Cancers in the Chinese Population.
- Jiang Y, Tian T, Yu C, Zhou W, Yang J, Wang Y, Wen Y, Chen J, Dai J, Jin G, Ma H, Shen H, Hu Z.
- Biomed Res Int. 2020 Aug 15;2020:6739823. doi: 10.1155/2020/6739823.
- PMID: 32879886
- PubMed abstract
-
- Prevalence and Spectrum of BRCA Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study.
- Foglietta J, Ludovini V, Bianconi F, Pistola L, Reda MS, Al-Refaie A, Tofanetti FR, Mosconi A, Minenza E, Anastasi P, Molica C, Stracci F, Roila F.
- Genes (Basel). 2020 Aug 12;11(8):E925. doi: 10.3390/genes11080925.
- PMID: 32806537
- PubMed abstract
- Source abstract
-
- Mutation in Exon2 of BRCA1 Gene in Adult Bengali Bangladeshi Female Patients with Breast Cancer: An Experience from Two Tertiary-Care Hospitals.
- Chowdhury SS, Khatun M, Khan TH, Laila AB.
- Asian Pac J Cancer Prev. 2020 Aug 1;21(8):2265-2270. doi: 10.31557/APJCP.2020.21.8.2265.
- PMID: 32856854
- PubMed abstract
- Source abstract
-
- Breast MRI texture analysis for prediction of BRCA-associated genetic risk.
- Vasileiou G, Costa MJ, Long C, Wetzler IR, Hoyer J, Kraus C, Popp B, Emons J, Wunderle M, Wenkel E, Uder M, Beckmann MW, Jud SM, Fasching PA, Cavallaro A, Reis A, Hammon M.
- BMC Med Imaging. 2020 Jul 29;20(1):86. doi: 10.1186/s12880-020-00483-2.
- PMID: 32727387
- PubMed abstract
-
- Clinicopathological characteristics of gene-positive breast cancer in the United Arab Emirates.
- Altinoz A, Al Ameri M, Qureshi W, Boush N, Nair SC, Abdel-Aziz A.
- Breast. 2020 Jul 27;53:119-124. doi: 10.1016/j.breast.2020.07.005. Epub ahead of print.
- PMID: 32745951
- PubMed abstract
-
- Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers.
- Glodzik D, Bosch A, Hartman J, Aine M, Vallon-Christersson J, Reuterswärd C, Karlsson A, Mitra S, Niméus E, Holm K, Häkkinen J, Hegardt C, Saal LH, Larsson C, Malmberg M, Rydén L, Ehinger A, Loman N, Kvist A, Ehrencrona H, Nik-Zainal S, Borg Å, Staaf J.
- Nat Commun. 2020 Jul 27;11(1):3747. doi: 10.1038/s41467-020-17537-2.
- PMID: 32719340
- PubMed abstract
-
- Homologous repair deficiency score for identifying breast cancers with defective DNA damage response.
- Min A, Kim K, Jeong K, Choi S, Kim S, Suh KJ, Lee KH, Kim S, Im SA.
- Sci Rep. 2020 Jul 27;10(1):12506. doi: 10.1038/s41598-020-68176-y.
- PMID: 32719318
- PubMed abstract
-
- BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer.
- Lips EH, Benard-Slagter A, Opdam M, Scheerman CE, Wesseling J, Hogervorst FBL, Linn SC, Savola S, Nederlof PM.
- Breast Cancer Res. 2020 Jul 25;22(1):79. doi: 10.1186/s13058-020-01313-7.
- PMID: 32711554
- PubMed abstract
-
- Expectations of Surveillance for Non-BRCA Gene Mutation Carriers at Increased Risk for Breast Cancer.
- Caskey R, Singletary B, Ayre K, Parker C, Krontiras H, Lancaster RB.
- J Surg Res. 2020 Jul 23;256:267-271. doi: 10.1016/j.jss.2020.06.029. Epub ahead of print.
- PMID: 32712440
- PubMed abstract
- Source abstract
-
- Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants.
- Barnes DR, Rookus MA, McGuffog L, Leslie G, Mooij TM, Dennis J, Mavaddat N, Adlard J, Ahmed M, Aittomäki K, Andrieu N, Andrulis IL, Arnold N, Arun BK, Azzollini J, Balmaña J, Barkardottir RB, Barrowdale D, Benitez J, Berthet P, Bialkowska K, Blanco AM, Blok MJ, Bonanni B, Boonen SE, Borg Å, Bozsik A, Bradbury AR, Brennan P, Brewer C, Brunet J, Buys SS, Caldés T, Caligo MA, Campbell I, Christensen LL, Chung WK, Claes KBM, Colas C; GEMO Study Collaborators; EMBRACE Collaborators, Collonge-Rame MA, Cook J, Daly MB, Davidson R, de la Hoya M, de Putter R, Delnatte C, Devilee P, Diez O, Ding YC, Domchek SM, Dorfling CM, Dumont M, Eeles R, Ejlertsen B, Engel C, Evans DG, Faivre L, Foretova L, Fostira F, Friedlander M, Friedman E, Frost D, Ganz PA, Garber J, Gehrig A, Gerdes AM, Gesta P, Giraud S, Glendon G, Godwin AK, Goldgar DE, González-Neira A, Greene MH, Gschwantler-Kaulich D, Hahnen E, Hamann U, Hanson H, Hentschel J, Hogervorst FBL, Hooning MJ, Horvath J, Hu C, Hulick PJ, Imyanitov EN; kConFab Investigators; HEBON Investigators; GENEPSO Investigators, Isaacs C, Izatt L, Izquierdo A, Jakubowska A, James PA, Janavicius R, John EM, Joseph V, Karlan BY, Kast K, Koudijs M, Kruse TA, Kwong A, Laitman Y, Lasset C, Lazaro C, Lester J, Lesueur F, Liljegren A, Loud JT, Lubinski J, Mai PL, Manoukian S, Mari V, Mebirouk N, Meijers-Heijboer HEJ, Meindl A, Mensenkamp AR, Miller A, Montagna M, Mouret-Fourme E, Mukherjee S, Mulligan AM, Nathanson KL, Neuhausen SL, Nevanlinna H, Niederacher D, Nielsen FC, Nikitina-Zake L, Noguès C, Olah E, Olopade OI, Ong KR, O'Shaughnessy-Kirwan A, Osorio A, Ott CE, Papi L, Park SK, Parsons MT, Pedersen IS, Peissel B, Peixoto A, Peterlongo P, Pfeiler G, Phillips KA, Prajzendanc K, Pujana MA, Radice P, Ramser J, Ramus SJ, Rantala J, Rennert G, Risch HA, Robson M, Rønlund K, Salani R, Schuster H, Senter L, Shah PD, Sharma P, Side LE, Singer CF, Slavin TP, Soucy P, Southey MC, Spurdle AB, Steinemann D, Steinsnyder Z, Stoppa-Lyonnet D, Sutter C, Tan YY, Teixeira MR, Teo SH, Thull DL, Tischkowitz M, Tognazzo S, Toland AE, Trainer AH, Tung N, van Engelen K, van Rensburg EJ, Vega A, Vierstraete J, Wagner G, Walker L, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Yadav S, Yang X, Yannoukakos D, Zimbalatti D, Offit K, Thomassen M, Couch FJ, Schmutzler RK, Simard J, Easton DF, Chenevix-Trench G, Antoniou AC; Consortium of Investigators of Modifiers of BRCA and BRCA2.
- Genet Med. 2020 Jul 15. doi: 10.1038/s41436-020-0862-x. Epub ahead of print.
- PMID: 32665703
- PubMed abstract
-
- Patterns and Prevalence of Germline BRCA1 and BRCA2 Mutations among High-Risk Breast Cancer Patients in Jordan: A Study of 500 Patients.
- Abdel-Razeq H, Abujamous L, Jadaan D.
- J Oncol. 2020 Jul 14;2020:8362179. doi: 10.1155/2020/8362179.
- PMID: 32733560
- PubMed abstract
-
- Molecular Features of Metaplastic Breast Carcinoma: An Infrequent Subtype of Triple Negative Breast Carcinoma.
- González-Martínez S, Pérez-Mies B, Carretero-Barrio I, Palacios-Berraquero ML, Perez-García J, Cortés J, Palacios J.
- Cancers (Basel). 2020 Jul 8;12(7):E1832. doi: 10.3390/cancers12071832.
- PMID: 32650408
- PubMed abstract
- Source abstract
- Review
- Free Full Text (PDF)
-
- Histopathologic features of breast cancer in Li-Fraumeni syndrome.
- Kuba MG, Lester SC, Bowman T, Stokes SM, Taneja KL, Garber JE, Dillon DA.
- Mod Pathol. 2020 Jul 7. doi: 10.1038/s41379-020-0610-4. Epub ahead of print.
- PMID: 32636452
- PubMed abstract
- Source abstract
-
- Breast cancer risk prediction models and subsequent tumor characteristics.
- Miller EA, Pinsky PF, Heckman-Stoddard BM, Minasian LM.
- Breast Cancer. 2020 Jul;27(4):662-669. doi: 10.1007/s12282-020-01060-9. Epub 2020 Feb 13.
- PMID: 32056079
- PubMed abstract
-
- Characterizations of Cancer Gene Mutations in Chinese Metastatic Breast Cancer Patients.
- Tao Z, Li T, Feng Z, Liu C, Shao Y, Zhu M, Gong C, Wang B, Cao J, Wang L, Du Y, Lizaso A, Li B, Zhang J, Hu X.
- Front Oncol. 2020 Jun 30;10:1023. doi: 10.3389/fonc.2020.01023.
- PMID: 32695676
- PubMed abstract
-
- Malignant fibroadenoma with CHEK2 mutation: a novel case.
- Ching D, Pirasteh S, Vora B, Martin R, Gill J.
- Pathology. 2020 Jun 27:S0031-3025(20)30829-1. doi: 10.1016/j.pathol.2020.04.009. Epub ahead of print.
- PMID: 32605861
- PubMed abstract
- Source abstract
-
- Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 Germline Mutation: A Multidisciplinary Clinical Review.
- Corso G, Montagna G, Figueiredo J, La Vecchia C, Fumagalli Romario U, Fernandes MS, Seixas S, Roviello F, Trovato C, Guerini-Rocco E, Fusco N, Pravettoni G, Petrocchi S, Rotili A, Massari G, Magnoni F, De Lorenzi F, Bottoni M, Galimberti V, Sanches JM, Calvello M, Seruca R, Bonanni B.
- Cancers (Basel). 2020 Jun 17;12(6):E1598. doi: 10.3390/cancers12061598.
- PMID: 32560361
- PubMed abstract
- Source abstract
-
- Clinical characteristics and exploratory genomic analyses of germline BRCA1 or BRCA2 mutations in breast cancer.
- Park S, Lee E, Park S, Lee S, Nam SJ, Kim SW, Lee JE, Yu JH, Kim JY, Ahn JS, Im YH, Park WY, Park K, Park YH.
- Mol Cancer Res. 2020 Jun 17:molcanres.1108.2019. doi: 10.1158/1541-7786.MCR-19-1108. Epub ahead of print.
- PMID: 32554602
- PubMed abstract
- Source abstract
-
- Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer.
- Baker LA, Holliday H, Roden D, Krisp C, Wu SZ, Junankar S, Serandour AA, Mohammed H, Nair R, Sankaranarayanan G, Law AMK, McFarland A, Simpson PT, Lakhani S, Dodson E, Selinger C, Anderson L, Samimi G, Hacker NF, Lim E, Ormandy CJ, Naylor MJ, Simpson K, Nikolic I, O'Toole S, Kaplan W, Cowley MJ, Carroll JS, Molloy M, Swarbrick A.
- Breast Cancer Res. 2020 Jun 11;22(1):63. doi: 10.1186/s13058-020-01306-6.
- PMID: 32527287
- PubMed abstract
-
- Germline Genetic Mutations in a Multi-center Contemporary Cohort of 550 Phyllodes Tumors: An Opportunity for Expanded Multi-gene Panel Testing.
- Rosenberger LH, Thomas SM, Nimbkar SN, Hieken TJ, Ludwig KK, Jacobs LK, Miller ME, Gallagher KK, Wong J, Neuman HB, Tseng J, Hassinger TE, Jakub JW.
- Ann Surg Oncol. 2020 Jun 5. doi: 10.1245/s10434-020-08480-z. Epub ahead of print.
- PMID: 32504368
- PubMed abstract
- Source abstract
-
- Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults.
- Watanabe T, Honda T, Totsuka H, Yoshida M, Tanioka M, Shiraishi K, Shimada Y, Arai E, Ushiama M, Tamura K, Yoshida T, Kanai Y, Kohno T.
- Breast Cancer Res Treat. 2020 Jun 3. doi: 10.1007/s10549-020-05716-0. Epub ahead of print.
- PMID: 32488393
- PubMed abstract
- Source abstract
-
- Suggested application of HER2+ breast tumor phenotype for germline TP53 variant classification within ACMG/AMP guidelines.
- Fortuno C, Mester J, Pesaran T, Weitzel JN, Dolinsky J, Yussuf A, McGoldrick K, Garber JE, Savage SA, Khincha PP, Gareth Evans D, Achatz MI, Nichols KE, Maxwell K, Schiffman JD, Sandoval R; Li-Fraumeni Exploration (LIFE) Consortium, James PA, Spurdle AB.
- Hum Mutat. 2020 Jun 2. doi: 10.1002/humu.24060. Epub ahead of print.
- PMID: 32485079
- PubMed abstract
- Source abstract
-
- Young onset breast cancer in Southern China - a 5-year clinico-pathological study from a multi-centre database.
- Co M, Kwong A.
- Cancer Treat Res Commun. 2020 May 30;24:100182. doi: 10.1016/j.ctarc.2020.100182. Epub ahead of print.
- PMID: 32534410
- PubMed abstract
-
- Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer.
- Chopra N, Tovey H, Pearson A, Cutts R, Toms C, Proszek P, Hubank M, Dowsett M, Dodson A, Daley F, Kriplani D, Gevensleben H, Davies HR, Degasperi A, Roylance R, Chan S, Tutt A, Skene A, Evans A, Bliss JM, Nik-Zainal S, Turner NC.
- Nat Commun. 2020 May 29;11(1):2662. doi: 10.1038/s41467-020-16142-7.
- PMID: 32471999
- PubMed abstract
-
- Genetic Testing and Screening Recommendations for Patients with Hereditary Breast Cancer.
- Bharucha PP, Chiu KE, François FM, Scott JL, Khorjekar GR, Tirada NP.
- Radiographics. 2020 May 29:190181. doi: 10.1148/rg.2020190181. Epub ahead of print.
- PMID: 32469631
- PubMed abstract
- Source abstract
Commentary:
Invited Commentary: Breast Cancer Risk Assessment and Screening Strategies-What's New?
- PMID: 32478602
- PubMed abstract
- Source abstract
-
- Increased prevalence of BRCA1/2 mutations in women with macro-textured breast implants and anaplastic large cell lymphoma of the breast.
- De Boer M, Hauptmann M, Hijmering NJ, van Noesel CJM, Rakhorst HA, Meijers-Heijboer HE, Boer JP, van der Hulst RR, De Jong D, van Leeuwen FE.
- Blood. 2020 May 26:blood.2019004498. doi: 10.1182/blood.2019004498. Epub ahead of print.
- PMID: 32452517
- PubMed abstract
- Source abstract
-
- Microsatellite instability and mismatch repair protein expressions in lymphocyte-predominant breast cancer.
- Horimoto Y, Thinzar Hlaing M, Saeki H, Kitano S, Nakai K, Sasaki R, Kurisaki-Arakawa A, Arakawa A, Otsuji N, Matsuoka S, Tokuda E, Arai M, Saito M.
- Cancer Sci. 2020 May 24. doi: 10.1111/cas.14500. Epub ahead of print.
- PMID: 32449246
- PubMed abstract
- Source abstract
-
- Clinical Characteristics of Korean Breast Cancer Patients Who Carry Pathogenic Germline Mutations in Both BRCA1 and BRCA2: A Single-Center Experience.
- Hur JY, Kim JY, Ahn JS, Im YH, Lee J, Kwon M, Park YH.
- Cancers (Basel). 2020 May 21;12(5):E1306. doi: 10.3390/cancers12051306.
- PMID: 32455662
- PubMed abstract
- Source abstract
-
- Comparison of mutation profile between primary phyllodes tumors of the breast and their paired local recurrences.
- Mitus J, Adamczyk A, Majchrzyk K, Kowalik A, Rys J, Niemiec J.
- Pol J Pathol. 2020 May 20;71(1):7-12. doi: 10.5114/pjp.2020.94899.
- PMID: 32429649
- PubMed abstract
- Source abstract
-
- Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women.
- Palmer JR, Polley EC, Hu C, John EM, Haiman C, Hart SN, Gaudet M, Pal T, Anton-Culver H, Trentham-Dietz A, Bernstein L, Ambrosone CB, Bandera EV, Bertrand KA, Bethea TN, Gao C, Gnanaolivu RD, Huang H, Lee KY, LeMarchand L, Na J, Sandler DP, Shah PD, Yadav S, Yang W, Weitzel JN, Domchek SM, Goldgar DE, Nathanson KL, Kraft P, Couch FJ.
- J Natl Cancer Inst. 2020 May 19:djaa040. doi: 10.1093/jnci/djaa040. Epub ahead of print.
- PMID: 32427313
- PubMed abstract
- Source abstract
Editorial:
Genetic Testing May Help Reduce Breast Cancer Disparities for African American Women.
- PMID: 32427327
- PubMed abstract
- Free Full Text
-
- Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.
- Zhang H, Ahearn TU, Lecarpentier J, Barnes D, Beesley J, Qi G, Jiang X, et al.
- Nat Genet. 2020 May 18. doi: 10.1038/s41588-020-0609-2. Epub ahead of print.
- PMID: 32424353
- PubMed abstract
- Source abstract
Research news: Breast Cancer Susceptibility GWAS Highlights Dozens New Loci, Some Subtype-Specific. (GenomeWeb)
Research news: Analysis of 100 Studies Reveals 32 New Sites of Genetic Variation Linked to Breast Cancer. (Clinical OMICS)
-
- BRCA Detection Rate in an Italian Cohort of Luminal Early-Onset and Triple-Negative Breast Cancer Patients without Family History: When Biology Overcomes Genealogy.
- Toss A, Molinaro E, Venturelli M, Domati F, Marcheselli L, Piana S, Barbieri E, Grandi G, Piombino C, Marchi I, Tenedini E, Tagliafico E, Tazzioli G, Cortesi L.
- Cancers (Basel). 2020 May 15;12(5):E1252. doi: 10.3390/cancers12051252.
- PMID: 32429297
- PubMed abstract
- Source abstract
-
- Clinicopathological characteristics of BRCA-associated breast cancer in Asian patients.
- Kim EK, Park SY, Kim SW.
- J Pathol Transl Med. 2020 May 14. doi: 10.4132/jptm.2020.04.07. Epub ahead of print.
- PMID: 32397691
- PubMed abstract
- Source abstract
- Review
- Free Full Text (PDF)
-
- A commentary on germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors.
- Kaname T.
- J Hum Genet. 2020 May 11. doi: 10.1038/s10038-020-0767-1. Epub ahead of print.
- PMID: 32393812
- PubMed abstract
- Commentary, Research review
- Free Full Text
Original research:
Germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors.
- PMID: 32029870
- PubMed abstract
- Source abstract
-
- Integrated molecular profiling of young and elderly patients with triple-negative breast cancer indicates different biological bases and clinical management strategies.
- Ma D, Jiang YZ, Xiao Y, Xie MD, Zhao S, Jin X, Xu XE, Shao ZM.
- Cancer. 2020 May 8. doi: 10.1002/cncr.32922. [Epub ahead of print]
- PMID: 32383785
- PubMed abstract
- Source abstract
-
- Pathogenic Variants in CHEK2 Are Associated With an Adverse Prognosis in Symptomatic Early-Onset Breast Cancer.
- Greville-Heygate SL, Maishman T, Tapper WJ, Cutress RI, Copson E, Dunning AM, Haywood L, Jones LJ, Eccles DM.
- JCO Precis Oncol. 2020 May 4;4:PO.19.00178. doi: 10.1200/PO.19.00178.
- PMID: 32923877
- PubMed abstract
- Source abstract
-
- [Case of Recurrent Breast Cancer with BRCA2 Mutation Successfully Treated with Olaparib Therapy].
- Yoneda H, Shimizu Y, Masuda R.
- Gan To Kagaku Ryoho. 2020 May;47(5):815-818.
- PMID: 32408326
- PubMed abstract
- Source abstract
-
- Clinical outcome of breast cancer in carriers of BRCA1 and BRCA2 mutations according to molecular subtypes.
- Talhouet S, Peron J, Vuilleumier A, Friedlaender A, Viassolo V, Ayme A, Bodmer A, Treilleux I, Lang N, Tille JC, Chappuis PO, Buisson A, Giraud S, Lasset C, Bonadona V, Trédan O, Labidi-Galy SI.
- Sci Rep. 2020 Apr 27;10(1):7073. doi: 10.1038/s41598-020-63759-1.
- PMID: 32341426
- PubMed abstract
-
- Evaluation of pathogenetic mutations in breast cancer predisposition genes in population-based studies conducted among Chinese women.
- Zeng C, Guo X, Wen W, Shi J, Long J, Cai Q, Shu XO, Xiang Y, Zheng W.
- Breast Cancer Res Treat. 2020 Apr 21. doi: 10.1007/s10549-020-05643-0. [Epub ahead of print]
- PMID: 32318955
- PubMed abstract
-
- Germline APOBEC3B deletion influences clinicopathological parameters in luminal-A breast cancer: evidences from a southern Brazilian cohort.
- Vitiello GAF, de Sousa Pereira N, Amarante MK, Banin-Hirata BK, Campos CZ, de Oliveira KB, Losi-Guembarovski R, Watanabe MAE.
- J Cancer Res Clin Oncol. 2020 Apr 13. doi: 10.1007/s00432-020-03208-8. [Epub ahead of print]
- PMID: 32285256
- PubMed abstract
- Source abstract
-
- Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women.
- Marker KM, Zavala VA, Vidaurre T, Lott PC, Vásquez JN, Casavilca-Zambrano S, Calderón M, Abugattas JE, Gómez HL, Fuentes HA, Picoaga RL, Cotrina JM, Neciosup SP, Castañeda CA, Morante Z, Valencia F, Torres J, Echeverry M, Bohórquez ME, Polanco-Echeverry G, Estrada-Florez AP, Serrano-Gómez SJ, Carmona-Valencia JA, Alvarado-Cabrero I, Sanabria-Salas MC, Velez A, Donado J, Song S, Cherry D, Tamayo LI, Huntsman S, Hu D, Ruiz-Cordero R, Balassanian R, Ziv E, Zabaleta J, Carvajal-Carmona L, Fejerman L; COLUMBUS Consortium.
- Cancer Res. 2020 Apr 3. doi: 10.1158/0008-5472.CAN-19-3659. [Epub ahead of print]
- PMID: 32245796
- PubMed abstract
- Source abstract
-
- Investigating the Link between Lynch Syndrome and Breast Cancer.
- Sheehan M, Heald B, Yanda C, Kelly ED, Grobmyer S, Eng C, Kalady M, Pederson H.
- Eur J Breast Health. 2020 Apr 1;16(2):106-109. doi: 10.5152/ejbh.2020.5198. eCollection 2020 Apr.
- PMID: 32285031
- PubMed abstract
- Source abstract
-
- Bilateral Paget's Disease of the Breast in a Patient with CHEK2 Mutation.
- Owusu-Brackett N, Menon PD, Nazarullah A, Jatoi I, Elmi M.
- Eur J Breast Health. 2020 Apr 1;16(2):152-154. doi: 10.5152/ejbh.2020.5568. eCollection 2020 Apr.
- PMID: 32285038
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text (PDF)
-
- Efficacy of platinum in advanced triple-negative breast cancer with germline BRCA mutation determined by next generation sequencing.
- Wang N, Li K, Huang W, Kong W, Liu X, Shi W, Xie F, Jiang H, Song G, Di L, Wang Q, Yu J, Li H.
- Chin J Cancer Res. 2020 Apr;32(2):149-162. doi: 10.21147/j.issn.1000-9604.2020.02.03.
- PMID: 32410793
- PubMed abstract
- Source abstract
-
- Clinicopathological analysis of early-stage breast cancer patients that meet indications for BRCA1/2 genetic testing.
- Xiang H, Xin L, Liu Q, Zhang H, Zhang S, Ye J, Cheng Y, Li T, Liu Y, Xu L.
- Chin J Cancer Res. 2020 Apr;32(2):163-174. doi: 10.21147/j.issn.1000-9604.2020.02.04.
- PMID: 32410794
- PubMed abstract
- Source abstract
-
- Germline Mutation in 1338 BRCA-Negative Chinese Hereditary Breast and/or Ovarian Cancer Patients: Clinical Testing with a Multigene Test Panel.
- Kwong A, Shin VY, Chen J, Cheuk IWY, Ho CYS, Au CH, Chan KKL, Ngan HYS, Chan TL, Ford JM, Ma ESK.
- J Mol Diagn. 2020 Apr;22(4):544-554. doi: 10.1016/j.jmoldx.2020.01.013. Epub 2020 Feb 15.
- PMID: 32068069
- PubMed abstract
- Source abstract
-
- Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers.
- McCrorie AD, Ashfield S, Begley A, Mcilmunn C, Morrison PJ, Boyd C, Eccles B, Greville-Heygate S, Copson ER, Cutress RI, Eccles DM, Savage KI, McIntosh SA.
- J Pathol Clin Res. 2020 Apr;6(2):146-153. doi: 10.1002/cjp2.155. Epub 2020 Feb 5.
- PMID: 32022473
- PubMed abstract
- Source abstract
-
- [Hereditary breast carcinomas pathologist's perspective].
- Vincent-Salomon A, Bataillon G, Djerroudi L.
- Ann Pathol. 2020 Mar 30. pii: S0242-6498(20)30059-6. doi: 10.1016/j.annpat.2020.02.023. [Epub ahead of print]
- PMID: 32241645
- PubMed abstract
- Source abstract
-
- Molecular Trajectory of BRCA1 and BRCA2 Mutations.
- Hatano Y, Tamada M, Matsuo M, Hara A.
- Front Oncol. 2020 Mar 25;10:361. doi: 10.3389/fonc.2020.00361. eCollection 2020.
- PMID: 32269964
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- An interesting case of likely BRCA2 related bilateral breast cancer with metastasis in the fimbrial part of fallopian tube.
- Boltežar L, Gašljevic G, Novakovic S, Stegel V, Škof E.
- Hered Cancer Clin Pract. 2020 Mar 19;18:7. doi: 10.1186/s13053-020-00139-w. eCollection 2020.
- PMID: 32206145
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- Association of Germline Variant Status With Therapy Response in High-risk Early-Stage Breast Cancer: A Secondary Analysis of the GeparOcto Randomized Clinical Trial.
- Pohl-Rescigno E, Hauke J, Loibl S, Möbus V, Denkert C, Fasching PA, Kayali M, Ernst C, Weber-Lassalle N, Hanusch C, Tesch H, Müller V, Altmüller J, Thiele H, Untch M, Lübbe K, Nürnberg P, Rhiem K, Furlanetto J, Lederer B, Jackisch C, Nekljudova V, Schmutzler RK, Schneeweiss A, Hahnen E.
- JAMA Oncol. 2020 Mar 12. doi: 10.1001/jamaoncol.2020.0007. [Epub ahead of print]
- PMID: 32163106
- PubMed abstract
- Source abstract
-
- Recurrent Germline BRCA2 Gene Mutation in Lithuanian Family.
- Sadzeviciene I, Jarmalaite S, Besusparis J, Liaugaudiene O, Asadauskiene J, Brasiuniene B, Kulikiene I, Sabaliauskaite R.
- Medicina (Kaunas). 2020 Mar 10;56(3). pii: E119. doi: 10.3390/medicina56030119.
- PMID: 32164353
- PubMed abstract
- Source abstract
- Case report
- Free Full Text (PDF)
-
- Tumour infiltrating lymphocytes and correlation with response to intensified platinum-based chemotherapy in BRCA-like tumours.
- Criscitiello C, Curigliano G.
- Eur J Cancer. 2020 Mar;127:236-239. doi: 10.1016/j.ejca.2019.12.004. Epub 2020 Jan 20.
- PMID: 31973961
- PubMed abstract
- Source abstract
-
- Breast Cancer in Men: A Single Center Experience Over a Period of 22 years.
- Hoffman A, Ben Ishay O, Horesh N, Shabtai M, Forschmidt E, Rosin D, Gutman M, Ram E.
- Isr Med Assoc J. 2020 Mar;22(3):160-163.
- PMID: 32147980
- PubMed abstract
-
- Molecular Mechanisms of PALB2 Function and Its Role in Breast Cancer Management.
- Wu S, Zhou J, Zhang K, Chen H, Luo M, Lu Y, Sun Y, Chen Y.
- Front Oncol. 2020 Feb 28;10:301. doi: 10.3389/fonc.2020.00301. eCollection 2020.
- PMID: 32185139
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- The contribution of germline predisposition gene mutations to clinical subtypes of invasive breast cancer from a clinical genetic testing cohort.
- Hu C, Polley EC, Yadav S, Lilyquist J, Shimelis H, Na J, Hart SN, Goldgar DE, Shah S, Pesaran T, Dolinsky JS, LaDuca H, Couch FJ.
- J Natl Cancer Inst. 2020 Feb 24. pii: djaa023. doi: 10.1093/jnci/djaa023. [Epub ahead of print]
- PMID: 32091585
- PubMed abstract
- Source abstract
-
- The spectrum of BRCA1 and BRCA2 mutations and clinicopathological characteristics in Chinese women with early-onset breast cancer.
- Chen L, Fu F, Huang M, Lv J, Zhang W, Wang C.
- Breast Cancer Res Treat. 2020 Feb 18. doi: 10.1007/s10549-020-05573-x. [Epub ahead of print]
- PMID: 32072338
- PubMed abstract
- Source abstract
-
- Genetic Variants Detected Using Cell-Free DNA from Blood and Tumor Samples in Patients with Inflammatory Breast Cancer.
- Winn JS, Hasse Z, Slifker M, Pei J, Arisi-Fernandez SM, Talarchek JN, Obeid E, Baldwin DA, Gong Y, Ross E, Cristofanilli M, Alpaugh RK, Fernandez SV.
- Int J Mol Sci. 2020 Feb 14;21(4). pii: E1290. doi: 10.3390/ijms21041290.
- PMID: 32075053
- PubMed abstract
- Source abstract
-
- Concordance of Hormone Receptor Status and BRCA1/2 Mutation Among Women With Synchronous Bilateral Breast Cancer.
- Huang L, Liu Q, Lang GT, Cao AY, Shao ZM.
- Front Oncol. 2020 Feb 11;10:27. doi: 10.3389/fonc.2020.00027. eCollection 2020.
- PMID: 32117708
- PubMed abstract
-
- Germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors.
- Hata C, Nakaoka H, Xiang Y, Wang D, Yang A, Liu D, Liu F, Zou Q, Wei L, Zheng K, Inoue I, You H.
- J Hum Genet. 2020 Feb 7. doi: 10.1038/s10038-020-0729-7. [Epub ahead of print]
- PMID: 32029870
- PubMed abstract
- Source abstract
Commentary, Research review:
A commentary on germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors
-
- Male Breast Cancer: Surgical and Genetic Features and a Multidisciplinary Management Strategy.
- Pellini F, Granuzzo E, Urbani S, Mirandola S, Caldana M, Lombardi D, Fiorio E, Mandarà M, Pollini GP.
- Breast Care (Basel). 2020 Feb;15(1):14-20. doi: 10.1159/000501711. Epub 2019 Sep 13.
- PMID: 32231493
- PubMed abstract
- Source abstract
-
- High risk of breast cancer in women with biallelic pathogenic variants in CHEK2.
- Rainville I, Hatcher S, Rosenthal E, Larson K, Bernhisel R, Meek S, Gorringe H, Mundt E, Manley S.
- Breast Cancer Res Treat. 2020 Jan 28. doi: 10.1007/s10549-020-05543-3. [Epub ahead of print]
- PMID: 31993860
- PubMed abstract
-
- Clinicopathological Features of Patients with the BRCA1 c.5339T>C (p.Leu1780Pro) Variant.
- Park HS, Ryu JM, Park , Im SA, Jung SY, Kim EK, Park WC, Min JW, Lee J, You JY, Lee JE, Kim SW.
- Cancer Res Treat. 2020 Jan 28. doi: 10.4143/crt.2019.351. [Epub ahead of print]
- PMID: 32019279
- PubMed abstract
- Source abstract
-
- The Clinical Spectrum of PTEN Mutations.
- Yehia L, Keel E, Eng C.
- Annu Rev Med. 2020 Jan 27;71:103-116. doi: 10.1146/annurev-med-052218-125823. Epub 2019 Aug 21.
- PMID: 31433956
- PubMed abstract
- Source abstract
-
- Effects of BRCA Germline Mutations on Triple-Negative Breast Cancer Prognosis.
- Pogoda K, Niwinska A, Sarnowska E, Nowakowska D, Jagiello-Gruszfeld A, Siedlecki J, Nowecki Z.
- J Oncol. 2020 Jan 27;2020:8545643. doi: 10.1155/2020/8545643. eCollection 2020.
- PMID: 32322271
- PubMed abstract
-
- Prospective Evaluation of Universal BRCA Testing for Women With Triple-Negative Breast Cancer.
- Emborgo TS, Saporito D, Muse KI, Barrera AMG, Litton JK, Lu KH, Arun BK.>
- JNCI Cancer Spectr. 2020 Jan 20;4(2):pkaa002. doi: 10.1093/jncics/pkaa002. eCollection 2020 Apr.
- PMID: 32211581
- PubMed abstract
-
- Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy.
- de Boo L, Cimino-Mathews A, Lubeck Y, Daletzakis A, Opdam M, Sanders J, Hooijberg E, van Rossum A, Loncova Z, Rieder D, Trajanoski Z, Vollebergh M, Sobral-Leite M, van de Vijver K, Broeks A, van der Wiel R, van Tinteren H, Linn S, Horlings HM, Kok M.
- Eur J Cancer. 2020 Jan 16. pii: S0959-8049(19)30855-X. doi: 10.1016/j.ejca.2019.12.003. [Epub ahead of print]
- PMID: 31956037
- PubMed abstract
- Source abstract
-
- Prognosis of BRCA1/2-negative breast cancer patients with HBOC risk factors compared with sporadic breast cancer patients without HBOC risk factors.
- Ryu JM, Nam SJ, Kim SW, Lee JE, Chae BJ, Lee SK, Yu J.
- Jpn J Clin Oncol. 2020 Jan 11. pii: hyz147. doi: 10.1093/jjco/hyz147. [Epub ahead of print]
- PMID: 31926487
- PubMed abstract
- Source abstract
-
- Imaging Features of Triple Negative Breast Cancer and the Effect of BRCA Mutations.
- Karbasian N, Sohrabi S, Omofoye TS, Le-Petross H, Arun BK, Albarracin CT, Hess KR, Gutierrez-Barrera AM, Whitman GJ.
- Curr Probl Diagn Radiol. 2020 Jan 8. pii: S0363-0188(20)30016-5. doi: 10.1067/j.cpradiol.2020.01.011. [Epub ahead of print]
- PMID: 32033821
- PubMed abstract
- Source abstract
-
- Comparison of clinical features and oncologic outcomes between familial (non-hereditary) and hereditary breast cancer in Korean female patients.
- Park CS, Park HY, Jung JH, Kim WW, Chae YS, Lee SJ, Park JY, Park JY, Lee J.
- Asian J Surg. 2020 Jan 7. pii: S1015-9584(19)30880-2. doi: 10.1016/j.asjsur.2019.12.001. [Epub ahead of print]
- PMID: 31924417
- PubMed abstract
-
- The relationship of breast density in mammography and magnetic resonance imaging in women with triple negative breast cancer.
- Mema E, Schnabel F, Chun J, Kaplowitz E, Price A, Goodgal J, Moy L.
- Eur J Radiol. 2020 Jan 7;124:108813. doi: 10.1016/j.ejrad.2020.108813. [Epub ahead of print]
- PMID: 31927471
- PubMed abstract
- Source abstract
-
- Microsatellite instability in Japanese female patients with triple-negative breast cancer.
- Kurata K, Kubo M, Kai M, Mori H, Kawaji H, Kaneshiro K, Yamada M, Nishimura R, Osako T, Arima N, Okido M, Oda Y, Nakamura M.
- Breast Cancer. 2020 Jan 6. doi: 10.1007/s12282-019-01043-5. [Epub ahead of print]
- PMID: 31907878
- PubMed abstract
-
- Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort.
- Cheng AS, Leung SCY, Gao D, Burugu S, Anurag M, Ellis MJ, Nielsen TO.
- Breast Cancer Res Treat. 2020 Jan;179(1):3-10. doi: 10.1007/s10549-019-05438-y. Epub 2019 Sep 14.
- PMID: 31522348
- PubMed abstract
Letter, Comment:
RE: Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort.
- PMID: 31950382
- PubMed abstract
- Free Full Text
-
- The Association Between Clinicopathological Features and Molecular Markers in Bahraini Women With Breast Cancer.
- AlZaman A, Ali E, Mohamad B, Islam M, AlZaman E, AlZaman Y.
- Gulf J Oncolog. 2020 Jan;1(32):19-25.
- PMID: 32342914
- PubMed abstract
- Source abstract
-
- Incorporating immunohistochemical markers into screening methods for BRCA1-mutated breast cancer.
- Tuzimek A, Fudalej M, Sobiborowicz A, Budzik M, Badowska-Kozakiewicz A.
- Pol J Pathol. 2020;71(3):261-269. doi: 10.5114/pjp.2020.99793.
- PMID: 33112117
- PubMed abstract
- Source abstract
-
- Profiling of the germline mutation BRCA1: p.Ile1845fs in a large cohort of Han Chinese breast cancer.
- Wu , Zhang H, Weng X, Wang H, Zhou Q, Wu Y, Shen Y, Hu Z.
- Hereditas. 2019 Dec 31;157:1. doi: 10.1186/s41065-019-0115-7. eCollection 2020.
- PMID: 31908633
- PubMed abstract
-
- Triple negative breast cancer: A thorough review of biomarkers.
- da Silva JL, Cardoso Nunes NC, Izetti P, de Mesquita GG, de Melo AC.
- Crit Rev Oncol Hematol. 2019 Dec 20;145:102855. doi: 10.1016/j.critrevonc.2019.102855. [Epub ahead of print]
- PMID: 31927455
- PubMed abstract
- Review
- Free Full Text
-
- CDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management.
- Shenoy S.
- Cancer Manag Res. 2019 Dec 13;11:10477-10486. doi: 10.2147/CMAR.S208818. eCollection 2019.
- PMID: 31853199
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- BRCA2 genemutation, c.2808_2811delACAA (p.Ala938Profs), in malebreastcancer - clinicopathologicalanalysisbased on a case report.
- Huszno J, Fiszer-Kierzkowska A, Piglowski W, Mazur M.
- Prz Menopauzalny. 2019 Dec;18(4):227-229. doi: 10.5114/pm.2019.93120. Epub 2020 Jan 15.
- PMID: 32132887
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain).
- Ruiz de Sabando A, Urrutia Lafuente E, García-Amigot F, Alonso Sánchez A, Morales Garofalo L, Moreno S, Ardanaz E, Ramos-Arroyo MA.
- BMC Cancer. 2019 Nov 27;19(1):1145. doi: 10.1186/s12885-019-6277-x.
- PMID: 31771539
- PubMed abstract
-
- Spectrum and clinical relevance of PALB2 germline mutations in 7657 Chinese BRCA1/2-negative breast cancer patients.
- Wu Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xu Y, Xie Y.
- Breast Cancer Res Treat. 2019 Nov 25. doi: 10.1007/s10549-019-05483-7. [Epub ahead of print]
- PMID: 31768816
- PubMed abstract
- Source abstract
-
- Radiotherapy-induced malignancies in breast cancer patients with TP53 pathogenic germline variants (Li-Fraumeni syndrome).
- Petry V, Bonadio RC, Cagnacci AQC, Senna LAL, Campos RDNG, Cotti GC, Hoff PM, Fragoso MCBV, Estevez-Diz MDP.
- Fam Cancer. 2019 Nov 20. doi: 10.1007/s10689-019-00153-5. [Epub ahead of print]
- PMID: 31748977
- PubMed abstract
- Source abstract
-
- Breast cancer surveillance for BRCA1/2 mutation carriers - is "early detection" early enough?
- Bernstein-Molho R, Kaufman B, Ben David MA, Sklair-Levy M, Feldman DM, Zippel D, Laitman Y, Friedman E.
- Breast. 2019 Nov 6;49:81-86. doi: 10.1016/j.breast.2019.10.012. [Epub ahead of print]
- PMID: 31760168
- PubMed abstract
-
- The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer.
- Figlioli G, Bogliolo M, Catucci I, Caleca L, Lasheras SV, Pujol R, Kiiski JI, Muranen TA, Barnes DR, Dennis J, Michailidou K, Bolla MK, Leslie G, Aalfs CM; ABCTB Investigators, Adank MA, Adlard J, Agata S, Cadoo K, Agnarsson BA, Ahearn T, Aittomäki K, Ambrosone CB, Andrews L, Anton-Culver H, Antonenkova NN, Arndt V, Arnold N, Aronson KJ, Arun BK, Asseryanis E, Auber B, Auvinen P, Azzollini J, Balmaña J, Barkardottir RB, Barrowdale D, Barwell J, Beane Freeman LE, Beauparlant CJ, Beckmann MW, Behrens S, Benitez J, Berger R, Bermisheva M, Blanco AM, Blomqvist C, Bogdanova NV, Bojesen A, Bojesen SE, Bonanni B, Borg A, Brady AF, Brauch H, Brenner H, Brüning T, Burwinkel B, Buys SS, Caldés T, Caliebe A, Caligo MA, Campa D, Campbell IG, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Claes KBM, Clarke CL, Collavoli A, Conner TA, Cox DG, Cybulski C, Czene K, Daly MB, de la Hoya M, Devilee P, Diez O, Ding YC, Dite GS, Ditsch N, Domchek SM, Dorfling CM, Dos-Santos-Silva I, Durda K, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flyger H, Foulkes WD, Friebel TM, Friedman E, Gabrielson M, Gaddam P, Gago-Dominguez M, Gao C, Gapstur SM, Garber J, García-Closas M, García-Sáenz JA, Gaudet MM, Gayther SA; GEMO Study Collaborators, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, Guénel P, Gutierrez-Barrera AM, Haeberle L, Haiman CA, Håkansson N, Hall P, Hamann U, Harrington PA, Hein A, Heyworth J, Hillemanns P, Hollestelle A, Hopper JL, Hosgood HD 3rd, Howell A, Hu C, Hulick PJ, Hunter DJ, Imyanitov EN; KConFab, Isaacs C, Jakimovska M, Jakubowska A, James P, Janavicius R, Janni W, John EM, Jones ME, Jung A, Kaaks R, Karlan BY, Khusnutdinova E, Kitahara CM, Konstantopoulou I, Koutros S, Kraft P, Lambrechts D, Lazaro C, Le Marchand L, Lester J, Lesueur F, Lilyquist J, Loud JT, Lu KH, Luben RN, Lubinski J, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martens JWM, Maurer T, Mavroudis D, Mebirouk N, Meindl A, Menon U, Miller A, Montagna M, Nathanson KL, Neuhausen SL, Newman WG, Nguyen-Dumont T, Nielsen FC, Nielsen S, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Olshan AF, Olson JE, Olsson H, Osorio A, Ottini L, Peissel B, Peixoto A, Peto J, Plaseska-Karanfilska D, Pocza T, Presneau N, Pujana MA, Punie K, Rack B, Rantala J, Rashid MU, Rau-Murthy R, Rennert G, Lejbkowicz F, Rhenius V, Romero A, Rookus MA, Ross EA, Rossing M, Rudaitis V, Ruebner M, Saloustros E, Sanden K, Santamariña M, Scheuner MT, Schmutzler RK, Schneider M, Scott C, Senter L, Shah M, Sharma P, Shu XO, Simard J, Singer CF, Sohn C, Soucy P, Southey MC, Spinelli JJ, Steele L, Stoppa-Lyonnet D, Tapper WJ, Teixeira MR, Terry MB, Thomassen M, Thompson J, Thull DL, Tischkowitz M, Tollenaar RAEM, Torres D, Troester MA, Truong T, Tung N, Untch M, Vachon CM, van Rensburg EJ, van Veen EM, Vega A, Viel A, Wappenschmidt B, Weitzel JN, Wendt C, Wieme G, Wolk A, Yang XR, Zheng W, Ziogas A, Zorn KK, Dunning AM, Lush M, Wang Q, McGuffog L, Parsons MT, Pharoah PDP, Fostira F, Toland AE, Andrulis IL, Ramus SJ, Swerdlow AJ, Greene MH, Chung WK, Milne RL, Chenevix-Trench G, Dörk T, Schmidt MK, Easton DF, Radice P, Hahnen E, Antoniou AC, Couch FJ, Nevanlinna H, Surrallés J, Peterlongo P.
- NPJ Breast Cancer. 2019 Nov 1;5:38. doi: 10.1038/s41523-019-0127-5. eCollection 2019.
- PMID: 31700994
- PubMed abstract
-
- Outcomes of women at high familial risk for breast cancer: An 8-year single-center experience.
- Lammert J, Skandarajah AR, Shackleton K, Calder P, Thomas S, Lindeman GJ, Mann GB.
- Asia Pac J Clin Oncol. 2019 Oct 28. doi: 10.1111/ajco.13274. [Epub ahead of print]
- PMID: 31657879
- PubMed abstract
- Source abstract
-
- Interval Breast Cancer Risk Associations with Breast Density, Family History, and Breast Tissue Ageing.
- Nguyen TL, Li S, Dite GS, Aung YK, Evans CF, Trinh HN, Baglietto L, Stone J, Song YM, Sung J, English DR, Jenkins MA, Dugué PA, Milne RL, Southey MC, Giles GG, Pike MC, Hopper JL.
- Int J Cancer. 2019 Oct 14. doi: 10.1002/ijc.32731. [Epub ahead of print]
- PMID: 31609476
- PubMed abstract
- Source abstract
-
- Mammographic Breast Density Assessed with Fully Automated Method and its Risk for Breast Cancer.
- J Clin Imaging Sci. 2019 Oct 11;9:43. doi: 10.25259/JCIS_70_2019. eCollection 2019.
- PMID: 31662951
- PubMed abstract
-
- Study of the PARP inhibitor talazoparib (Talzenna) for early-stage breast cancer is promising.
- [No author given]
- FORCE. XRAYS. 2019 Oct 4.
- Research news
- Free Full Text
Original research:
Neoadjuvant Talazoparib for Patients With Operable Breast Cancer With a Germline BRCA Pathogenic Variant.
- PMID: 31461380
- PubMed abstract
- Free Full Text
-
- Distinct Alterations in Tricarboxylic Acid Cycle Metabolites Associate with Cancer and Autism Phenotypes in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome.
- Yehia L, Ni Y, Feng F, Seyfi M, Sadler T, Frazier TW, Eng C.
- Am J Hum Genet. 2019 Oct 3;105(4):813-821. doi: 10.1016/j.ajhg.2019.09.004. Epub 2019 Sep 26.
- PMID: 31564436
- PubMed abstract
-
- Patterns of recurrence and metastasis in BRCA1/BRCA2-associated breast cancers.
- Song Y, Barry WT, Seah DS, Tung NM, Garber JE, Lin NU.
- Cancer. 2019 Oct 3. doi: 10.1002/cncr.32540. [Epub ahead of print]
- PMID: 31581314
- PubMed abstract
- Source abstract
-
- Mexican BRCA1 founder mutation: Shortening the gap in genetic assessment for hereditary breast and ovarian cancer patients.
- Fragoso-Ontiveros V, Velázquez-Aragón JA, Nuñez-Martínez PM, de la Luz Mejía-Aguayo M, Vidal-Millán S, Pedroza-Torres A, Sánchez-Contreras Y, Ramírez-Otero MA, Muñiz-Mendoza R, Domínguez-Ortíz J, Wegman-Ostrosky T, Bargalló-Rocha JE, Gallardo-Rincón D, Reynoso-Noveron N, Arriaga-Canon C, Meneses-García A, Herrera-Montalvo LA, Alvarez-Gomez RM.
- PLoS One. 2019 Sep 23;14(9):e0222709. doi: 10.1371/journal.pone.0222709. eCollection 2019.
- PMID: 31545835
- PubMed abstract
-
- Prevalence and clinical outcomes of germline mutations in BRCA1/2 and PALB2 genes in 2769 unselected breast cancer patients in China.
- Deng M, Chen HH, Zhu X, Luo M, Zhang K, Xu CJ, Hu KM, Cheng P, Zhou JJ, Zheng S, Chen YD.
- Int J Cancer. 2019 Sep 15;145(6):1517-1528. doi: 10.1002/ijc.32184. Epub 2019 Feb 22.
- PMID: 30720863
- PubMed abstract
- Source abstract
-
- Breast Cancer Screening in BRCA Mutation Carriers: Necessity of a Relevant Update of Mammographic Modalities.
- Colin C, Doutriaux-Dumoulin I.
- Radiology. 2019 Sep 3:191306. doi: 10.1148/radiol.2019191306. [Epub ahead of print]
- PMID: 31478804
- PubMed abstract
- Source abstract
Original research:
BRCA Mutation Carriers: Breast and Ovarian Cancer Screening Guidelines and Imaging Considerations.
- PMID: 31038410
- PubMed abstract
- Free Full Text
-
- BRCA1 promoter methylation in peripheral blood is associated with the risk of triple-negative breast cancer.
- Prajzendanc K, Domagała P, Hybiak J, Ryś J, Huzarski T, Szwiec M, Tomiczek-Szwiec J, Redelbach W, Sejda A, Gronwald J, Kluz T, Wiśniowski R, Cybulski C, Łukomska A, Białkowska K, Sukiennicki G, Kulczycka K, Narod SA, Wojdacz TK, Lubiński J, Jakubowska A.
- Int J Cancer. 2019 Aug 30. doi: 10.1002/ijc.32655. [Epub ahead of print]
- PMID: 31469414
- PubMed abstract
- Source abstract
-
- Neoadjuvant Talazoparib for Patients With Operable Breast Cancer With a Germline BRCA Pathogenic Variant.
- Litton JK, Scoggins ME, Hess KR, Adrada BE, Murthy RK, Damodaran S, DeSnyder SM, Brewster AM, Barcenas CH, Valero V, Whitman GJ, Schwartz-Gomez J, Mittendorf EA, Thompson AM, Helgason T, Ibrahim N, Piwnica-Worm H1, Moulder SL, Arun BK.
- J Clin Oncol. 2019 Aug 28:JCO1901304. doi: 10.1200/JCO.19.01304. [Epub ahead of print]
- PMID: 31461380
- PubMed abstract
- Source abstract
Research news: Study of the PARP inhibitor talazoparib (Talzenna) for early-stage breast cancer is promising. (FORCE. XRAYS.)
-
- Risk factors for triple negative breast cancer among Latina women.
- Rey-Vargas L, Sanabria Salas MC, Fejerman L, Serrano-Gómez SJ.
- Cancer Epidemiol Biomarkers Prev. 2019 Aug 27. pii: cebp.0035.2019. doi: 10.1158/1055-9965.EPI-19-0035. [Epub ahead of print]
- PMID: 31455670
- PubMed abstract
- Source abstract
-
- A novel BRCA1 germline mutation promotes triple-negative breast cancer cells progression and enhances sensitivity to DNA damage agents.
- Xu K, Shi Y, Wang X, Chen Y, Tang L, Guan X.
- Cancer Genet. 2019 Aug 23;239:26-32. doi: 10.1016/j.cancergen.2019.08.004. [Epub ahead of print]
- PMID: 31476665
- PubMed abstract
- Source abstract
-
- Pathology of BRCA1- and BRCA2-associated Breast Cancers: Known and Less Known Connections.
- Fountzilas E, Konstantopoulou I, Vagena A, Apostolou P, Papadimitriou C, Christodoulou C, Tryfonopoulos D5, Manousou K, Delimitsou A, Papamentzelopoulou M, Fountzilas G, Yannoukakos D, Fostira F.
- Clin Breast Cancer. 2019 Aug 22. pii: S1526-8209(19)30642-1. doi: 10.1016/j.clbc.2019.08.003. [Epub ahead of print]
- PMID: 31980407
- PubMed abstract
- Source abstract
-
- Influence of BRCA1 Germline Mutations in the Somatic Mutational Burden of Triple-Negative Breast Cancer.
- Ferreira EN, Brianese RC, de Almeida RVB, Drummond RD, de Souza JE, da Silva IT, de Souza SJ, Carraro DM.
- Transl Oncol. 2019 Aug 13;12(11):1453-1460. doi: 10.1016/j.tranon.2019.07.016. [Epub ahead of print]
- PMID: 31419696
- PubMed abstract
-
- Functional analysis of clinical BARD1 germline variants.
- Toh MR, Chong ST, Chan SH, Low CE, Ishak NDB, Lim JQ, Courtney E, Ngeow J.
- Cold Spring Harb Mol Case Stud. 2019 Aug 1;5(4). pii: a004093. doi: 10.1101/mcs.a004093. Print 2019 Aug.
- PMID: 31371347
- PubMed abstract
- Source abstract
-
- MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc): a multicentre, randomised, controlled trial.
- Saadatmand S, Geuzinge HA, Rutgers EJT, Mann RM, de Roy van Zuidewijn DBW, Zonderland HM, Tollenaar RAEM, Lobbes MBI, Ausems MGEM, van 't Riet M, Hooning MJ, Mares-Engelberts I, Luiten EJT, Heijnsdijk EAM, Verhoef C, Karssemeijer N, Oosterwijk JC, Obdeijn IM, de Koning HJ, Tilanus-Linthorst MMA; FaMRIsc study group.
- Lancet Oncol. 2019 Aug;20(8):1136-1147. doi: 10.1016/S1470-2045(19)30275-X. Epub 2019 Jun 17.
- PMID: 31221620
- PubMed abstract
- Source abstract
Comment:
Underdiagnosis is the main challenge in breast cancer screening.
- PMID: 31221618
- PubMed abstract
- Source abstract
Letter, Commentary:
MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc).
- PMID: 31486364
- PubMed abstract
- Free Full Text
Research news: MRI or mammograms for detecting breast cancer in families with unknown genetic mutations? (FORCE. XRAYS.)
-
- Molecular characteristics of breast cancer according to clinicopathological factors.
- Huszno J, Kolosza Z.
- Mol Clin Oncol. 2019 Aug;11(2):192-200. doi: 10.3892/mco.2019.1869. Epub 2019 May 28.
- PMID: 31281656
- PubMed abstract
- Source abstract
-
- Transforming growth factor beta receptor II (TGFBR2) promoter region polymorphism in Brazilian breast cancer patients: association with susceptibility, clinicopathological features, and interaction with TGFB1 haplotypes.
- Vitiello GAF, Amarante MK, Banin-Hirata BK, Campos CZ, de Oliveira KB, Losi-Guembarovski R, Watanabe MAE.
- Breast Cancer Res Treat. 2019 Jul 30. doi: 10.1007/s10549-019-05370-1. [Epub ahead of print]
- PMID: 31364002
- PubMed abstract
- Source abstract
-
- In BRCA mutation carriers breast conserving surgery may not be the best choice.
- Trimboli RM, Schiaffino S, Sardanelli F.
- Breast Cancer Res Treat. 2019 Jul 27. doi: 10.1007/s10549-019-05373-y. [Epub ahead of print]
- PMID: 31352555
- PubMed abstract
- Source abstract
Original research:
Risk of ipsilateral breast tumor recurrence in primary invasive breast cancer following breast-conserving surgery with BRCA1 and BRCA2 mutation in China.
- PMID: 30895535
- PubMed abstract
- Source abstract
-
- CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer.
- Frick E, Gudjonsson T, Eyfjord J, Jonasson J, Tryggvadóttir L, Stefansson O, Sigurdsson S.
- Oncotarget. 2019 Jul 23;10(45):4664-4678. doi: 10.18632/oncotarget.27083. eCollection 2019 Jul 23.
- PMID: 31384394
- PubMed abstract
- Source abstract
-
- Analysis of the pathogenic variants of BRCA1 and BRCA2 using next-generation sequencing in women with familial breast cancer: a case-control study.
- Zayas-Villanueva OA, Campos-Acevedo LD, Lugo-Trampe JJ, Hernández-Barajas D, González-Guerrero JF, Noriega-Iriondo MF, Ramírez-Sánchez IA, Martínez-de-Villarreal LE.
- BMC Cancer. 2019 Jul 22;19(1):722. doi: 10.1186/s12885-019-5950-4.
- PMID: 31331294
- PubMed abstract
-
- Benign breast disease increases breast cancer risk independent of underlying familial risk profile: Findings from a Prospective Family Study Cohort.
- Zeinomar N, Phillips KA, Daly MB, Milne RL, Dite GS, MacInnis RJ, Liao Y, Kehm RD, Knight JA, Southey MC, Chung WK, Giles GG, McLachlan SA, Friedlander ML, Weideman PC, Glendon G, Nesci S; kConFab Investigators, Andrulis IL, Buys SS, John EM, Hopper JL, Terry MB.
- Int J Cancer. 2019 Jul 15;145(2):370-379. doi: 10.1002/ijc.32112. Epub 2019 Feb 20.
- PMID: 30725480
- PubMed abstract
- Source abstract
-
- A Review of the Hereditary Component of Triple Negative Breast Cancer: High- and Moderate-Penetrance Breast Cancer Genes, Low-Penetrance Loci, and the Role of Nontraditional Genetic Elements.
- Ellsworth DL, Turner CE, Ellsworth RE.
- J Oncol. 2019 Jul 9;2019:4382606. doi: 10.1155/2019/4382606. eCollection 2019.
- PMID: 31379942
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- The molecular genetic make-up of male breast cancer.
- Moelans CB, de Ligt J, van der Groep P, Prins P4, Besselink N, Hoogstraat M, Ter Hoeve N, Lacle M, Kornegoor R, van der Pol C, de Leng W, Barbe E, van der Vegt B, Martens J, Bult P, Smits VT, Koudijs M, Nijman I, Voest E, Selenica P, Weigelt B, Reis-Filho J, van der Wall E, Cuppen E, van Diest PJ.
- Endocr Relat Cancer. 2019 Jul 1. pii: ERC-19-0278. doi: 10.1530/ERC-19-0278. [Epub ahead of print]
- PMID: 31340200
- PubMed abstract
- Source abstract
-
- Frequency of Pathogenic Germline Variants in CDH1, BRCA2, CHEK2, PALB2, BRCA1, and TP53 in Sporadic Lobular Breast Cancer.
- Petridis C, Arora I, Shah V, Moss CL, Mera A, Clifford A, Gillett C, Pinder SE, Tomlinson I, Roylance R, Simpson MA, Sawyer EJ.
- Cancer Epidemiol Biomarkers Prev. 2019 Jul;28(7):1162-1168. doi: 10.1158/1055-9965.EPI-18-1102.
- PMID: 31263054
- PubMed abstract
- Source abstract
-
- Identification of BRCA1/2 p.Ser1613Gly, p.Pro871Leu, p.Lys1183Arg, p.Glu1038Gly, p.Ser1140Gly, p.Ala2466Val, p.His2440Arg variants in women under 45 years old with breast nodules suspected of having breast cancer in Burkina Faso.
- Sagna T, Bonora E, Ouedraogo MNL, Fusco D, Zoure AA, Bisseye C, Djigma F, Kafando JG, Zongo N, Douamba Z, Obiri-Yeboah D, Turchetti D, Pietra V, Lompo OM, Ouedraogo C, Seri M, Simpore J.
- Biomol Concepts. 2019 Jun 11;10(1):120-127. doi: 10.1515/bmc-2019-0015.
- PMID: 31203256
- PubMed abstract
-
- Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria.
- Wang S, Pitt JJ, Zheng Y, Yoshimatsu TF, Gao G, Sanni A, Oluwasola O, Ajani M, Fitzgerald D, Odetunde A, Khramtsova G, Hurley I, Popoola A, Falusi A, Ogundiran T, Obafunwa J, Ojengbede O, Ibrahim N, Barretina J, White KP, Huo D, Olopade O.
- Int J Cancer. 2019 Jun 7. doi: 10.1002/ijc.32498. [Epub ahead of print]
- PMID: 31173346
- PubMed abstract
- Source abstract
-
- Differential Profile of BRCA1 vs. BRCA2 Mutated Families: A Characterization of the Main Differences and Similarities in Patients.
- Fernandes GC, Felicio PS, Michelli RAD, Coelho AS, Scapulatempo-Neto C, Palmero EI.
- Asian Pac J Cancer Prev. 2019 Jun 1;20(6):1655-1660. doi: 10.31557/APJCP.2019.20.6.1655.
- PMID: 31244284
- PubMed abstract
- Source abstract
-
- Novel germline STK11 variants and breast cancer phenotype identified in an Indian cohort of Peutz-Jeghers syndrome.
- Lipsa A, Kowtal P, Sarin R.
- Hum Mol Genet. 2019 Jun 1;28(11):1885-1893. doi: 10.1093/hmg/ddz027.
- PMID: 30689838
- PubMed abstract
- Source abstract
-
- [Breast Cancer in BRCA1/2 Mutation Carriers - Do We Treat It Differently? Focus on Systemic Therapy for BRCA1/2 Associated Breast Cancer.]
- Palácová M.
- Klin Onkol. 2019 Summer;32(Supplementum2):24-30. doi: 10.14735/amko2019S24.
- PMID: 31409078
- PubMed abstract
- Source abstract
- Review, [Article in Czech], English Abstract
- Free Full Text - Czech (PDF)
-
- [Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition - Mutation Types and their Biological and Clinical Relevance.]
- Kleiblová P, Stolařová L, Křížová K, Lhota F, Hojný J, Zemánková P, Havránek O, Vočka M, Černá M, Lhotová K, Borecká M, Janatová M, Soukupová J, Ševčík J, Zimovjanová M, Kotlas J, Panczak A, Veselá K, Červenková J, Schneiderová M, Burócziová M, Burdová K, Stránecký V, Foretová L, Macháčková E, Tavandzis S, Kmoch S, Macůrek L, Kleibl Z.
- Klin Onkol. 2019 Summer;32(Supplementum2):36-50. doi: 10.14735/amko2019S36.
- PMID: 31409080
- PubMed abstract
- Source abstract
- [Article in Czech], English Abstract
- Free Full Text - Czech (PDF)
-
- Risk of ipsilateral breast tumor recurrence in primary invasive breast cancer following breast-conserving surgery with BRCA1 and BRCA2 mutation in China.
- Cao W, Xie Y, He Y, Li J, Wang T, Fan Z, Fan T, Ouyang T.
- Breast Cancer Res Treat. 2019 Jun;175(3):749-754. doi: 10.1007/s10549-019-05199-8. Epub 2019 Mar 20.
- PMID: 30895535
- PubMed abstract
- Source abstract
Letter, Commentary:
In BRCA mutation carriers breast conserving surgery may not be the best choice.
- PMID: 31352555
- PubMed abstract
- Source abstract
-
- Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC).
- Lo W, Zhu B, Sabesan A, Wu HH, Powers A, Sorber RA, Ravichandran S, Chen I, McDuffie LA, Quadri HS, Beane JD, Calzone K, Miettinen MM, Hewitt SM, Koh C, Heller T, Wacholder S, Rudloff U.
- J Med Genet. 2019 Jun;56(6):370-379. doi: 10.1136/jmedgenet-2018-105361. Epub 2019 Feb 11.
- PMID: 30745422
- PubMed abstract
- Source abstract
-
- The Landscape of Somatic Genetic Alterations in Breast Cancers from CHEK2 Germline Mutation Carriers.
- Mandelker D, Kumar R, Pei X, Selenica P, Setton J, Arunachalam S, Ceyhan-Birsoy O, Brown DN, Norton L, Robson ME, Wen HY, Powell S, Riaz N, Weigelt B, Reis-Filho JS.
- JNCI Cancer Spectr. 2019 Apr 27;3(2):pkz027. doi: 10.1093/jncics/pkz027. eCollection 2019 Jun.
- PMID: 31360903
- PubMed abstract
-
- Molecular comparison of interval and screen-detected breast cancers.
- Cheasley D, Li N, Rowley SM, Elder K, Mann GB, Loi S, Savas P, Goode DL, Kader T, Zethoven M, Semple T, Fox SB, Pang JM, Byrne D, Devereux L, Nickson C, Procopio P, Lee G, Hughes S, Saunders H, Fujihara KM, Kuykhoven K, Connaughton J, James PA, Gorringe KL, Campbell IG.
- J Pathol. 2019 Jun;248(2):243-252. doi: 10.1002/path.5251. Epub 2019 Mar 8.
- PMID: 30746706
- PubMed abstract
- Source abstract
-
- Male breast cancer: Specific biological characteristics and survival in a Portuguese cohort.
- André S, Pereira T, Silva F, Machado P, Vaz F, Aparício M, Silva GL, Pinto AE.
- Mol Clin Oncol. 2019 Jun;10(6):644-654. doi: 10.3892/mco.2019.1841. Epub 2019 Apr 8.
- PMID: 31031981
- PubMed abstract
- Source abstract
-
- Estrogen Receptor Status Oppositely Modifies Breast Cancer Prognosis in BRCA1/BRCA2 Mutation Carriers Versus Non-Carriers.
- Vocka M, Zimovjanova M, Bielcikova Z, Tesarova P, Petruzelka L, Mateju M, Krizova L, Kotlas J, Soukupova J, Janatova M, Zemankova P, Kleiblova P, Novotny J, Konopasek B, Chodacka M, Brychta M, Sochor M, Smejkalova-Musilova D, Cmejlova V, Kozevnikovova R, Miskarova L, Argalacsova S, Stolarova L, Lhotova K, Borecka M, Kleibl Z.
- Cancers (Basel). 2019 May 28;11(6). pii: E738. doi: 10.3390/cancers11060738.
- PMID: 31141992
- PubMed abstract
- Source abstract
-
- BARD1 is A Low/Moderate Breast Cancer Risk Gene: Evidence Based on An Association Study of the Central European p.Q564X Recurrent Mutation.
- Suszynska M, Kluzniak W, Wokolorczyk D, Jakubowska A, Huzarski T, Gronwald J, Debniak T, Szwiec M, Ratajska M, Klonowska K, Narod S, Bogdanova N, Dörk T, Lubinski J, Cybulski C, Kozlowski P.
- Cancers (Basel). 2019 May 28;11(6). pii: E740. doi: 10.3390/cancers11060740.
- PMID: 31142030
- PubMed abstract
- Source abstract
-
- Breast cancer histologic subtypes show excess familial clustering.
- Henry NL, Cannon-Albright LA.
- Cancer. 2019 May 23. doi: 10.1002/cncr.32198. [Epub ahead of print]
- PMID: 31120568
- PubMed abstract
- Source abstract
-
- Metaplastic breast cancer has a poor response to neoadjuvant systemic therapy.
- Al-Hilli Z, Choong G, Keeney MG, Visscher DW, Ingle JN, Goetz MP, Jakub JW.
- Breast Cancer Res Treat. 2019 May 22. doi: 10.1007/s10549-019-05264-2. [Epub ahead of print]
- PMID: 31119569
- PubMed abstract
- Source abstract
-
- Analysis of clinical characteristics of breast cancer patients with the Japanese founder mutation BRCA1 L63X.
- Yoshida R, Watanabe C, Yokoyama S, Inuzuka M, Yotsumoto J, Arai M, Nakamura S, the Registration Committee of the Japanese HBOC consortium.
- Oncotarget. 2019 May 14;10(35):3276-3284. doi: 10.18632/oncotarget.26852. eCollection 2019 May 14.
- PMID: 31143373
- PubMed abstract
- Source abstract
-
- A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases.
- Tyran M, Carbuccia N, Garnier S, Guille A, Adelaïde J, Finetti P, Toulzian J, Viens P, Tallet A, Goncalves A, Metellus P, Birnbaum D, Chaffanet M, Bertucci F.
- Cancers (Basel). 2019 May 13;11(5):665. doi: 10.3390/cancers11050665.
- PMID: 31086113
- PubMed abstract
- Source abstract
-
- Frequency of pathogenic germline variants in BRCA1, BRCA2, PALB2, CHEK2 and TP53 in ductal carcinoma in situ diagnosed in women under the age of 50 years.
- Petridis C, Arora I, Shah V, Megalios A, Moss C, Mera A, Clifford A, Gillett C, Pinder SE, Tomlinson I, Roylance R, Simpson MA, Sawyer EJ.
- Breast Cancer Res. 2019 May 6;21(1):58. doi: 10.1186/s13058-019-1143-y.
- PMID: 31060593
- PubMed abstract
-
- Non-BRCA1/2 Variants Detected in a High-Risk Chilean Cohort With a History of Breast and/or Ovarian Cancer.
- Adaniel C, Salinas F, Donaire JM, Bravo ME, Peralta O, Paredes H, Aliaga N, Sola A, Neira P, Behnke C, Rodriguez T, Torres S, Lopez F, Hurtado C.
- J Glob Oncol. 2019 May;(5):1-14. doi: 10.1200/JGO.18.00163.
- PMID: 31125277
- PubMed abstract
- Source abstract
-
- Breast cancer in patients with germline TP53 pathogenic variants have typical tumour characteristics - the Cohort study of TP53 carrier early onset breast cancer (COPE study).
- Packwood K, Martland G, Sommerlad M, Shaw E, Moutasim K, Thomas G, Bateman A, Jones L, Haywood L, Evans DG, Birch JM, Alsalmi OA, Henderson A, Poplawski N, Eccles DM.
- J Pathol Clin Res. 2019 Apr 30. doi: 10.1002/cjp2.133. [Epub ahead of print]
- PMID: 31041842
- PubMed abstract
- Source abstract
-
- BRCA Mutation Carriers: Breast and Ovarian Cancer Screening Guidelines and Imaging Considerations.
- Elezaby M, Lees B, Maturen KE, Barroilhet L, Wisinski KB, Schrager S, Wilke LG, Sadowski E.
- Radiology. 2019 Apr 30:181814. doi: 10.1148/radiol.2019181814. [Epub ahead of print]
- PMID: 31038410
- PubMed abstract
- Source abstract
- Review
- Free Full Text
Letter, Comment:
Breast Cancer Screening in BRCA Mutation Carriers: Necessity of a Relevant Update of Mammographic Modalities.
- PMID: 31478804
- PubMed abstract
- Source abstract
-
- Reviewing the characteristics of BRCA and PALB2-related cancers in the precision medicine era.
- Macedo GS, Alemar B, Ashton-Prolla P.
- Genet Mol Biol. 2019 Apr 29. pii: S1415-47572019005015101. doi: 10.1590/1678-4685-GMB-2018-0104. [Epub ahead of print]
- PMID: 31067289
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation.
- Lee HE, Arshad M, Brahmbhatt RD, Hoskin TL, Winham SJ, Frost MH, Radisky DC, Denison LA, Degnim AC, Visscher DW.
- Mod Pathol. 2019 Apr 17. doi: 10.1038/s41379-019-0217-9. [Epub ahead of print]
- PMID: 30996252
- PubMed abstract
- Source abstract
-
- Germline mutation landscape of Chinese patients with familial breast/ovarian cancer in a panel of 22 susceptibility genes.
- Wang J, Li W, Shi Y, Huang Y, Sun T, Tang L, Lu Q, Lei Q, Liao N, Jin F, Li H, Huang T, Qian J, Pang D, Wang S, Fan P, Wu X, Lin Y, Qin H, Xu B.
- Cancer Med. 2019 Apr 13. doi: 10.1002/cam4.2093. [Epub ahead of print]
- PMID: 30982232
- PubMed abstract
- Source abstract
-
- Five screening-detected breast cancer cases in initially disease-free BRCA1 or BRCA2 mutation carriers.
- Shimada S, Yoshida R, Nakashima E, Kitagawa D, Gomi N, Horii R, Takeuchi S, Ashihara Y, Kita M, Akiyama F, Ohno S, Saito M, Arai M.
- Breast Cancer. 2019 Apr 12. doi: 10.1007/s12282-019-00971-6. [Epub ahead of print]
- PMID: 30980249
- PubMed abstract
- Case report
- Free Full Text
-
- Contribution of BRCA1 5382insC mutation in triple negative breast cancer in Tunisia.
- Mahfoudh W, Bettaieb I, Ghedira R, Snoussi K, Bouzid N, Klayech Z, Gabbouj S, Remadi Y, Hassen E, Bouaouina N, Zakhama A.
- J Transl Med. 2019 Apr 11;17(1):123. doi: 10.1186/s12967-019-1873-8.
- PMID: 30975216
- PubMed abstract
-
- Prevalence of BRCA1 and BRCA2 gene mutations in Chinese patients with high-risk breast cancer.
- Wang X, Liu H, Maimaitiaili A, Zhao G, Li S, Lv Z, Wu D, Shi A, Guan X, Jia H, Li M, Song D, Kang L, Han B, Fu T, Yang M, Zhu Z, Du Y, Song Y, Hong J, Fan Z.
- Mol Genet Genomic Med. 2019 Apr 9:e677. doi: 10.1002/mgg3.677. [Epub ahead of print]
- PMID: 30968603
- PubMed abstract
- Source abstract
-
- Multidisciplinary management of CDH1 germinal mutation and prophylactic management hereditary lobular breast cancer: A case report.
- Mirandola S, Pellini F, Granuzzo E, Lorenzi M, Accordini B, Ulgelmo M, Invento A, Lombardi D, Caldana M, Pollini GP.
- Int J Surg Case Rep. 2019 Apr 5;58:92-95. doi: 10.1016/j.ijscr.2019.03.053. [Epub ahead of print]
- PMID: 31028995
- PubMed abstract
- Case report
- Free Full Text
-
- Combined tumor sequencing and case/control analyses of RAD51C in breast cancer.
- Li N, McInerny S, Zethoven M, Cheasley D, Lim BWX, Rowley SM, Devereux L, Grewal N, Ahmadloo S, Byrne D, Lee JEA, Li J, Fox SB, John T, Antill Y, Gorringe KL, James PA, Campbell IG.
- J Natl Cancer Inst. 2019 Apr 5. pii: djz045. doi: 10.1093/jnci/djz045. [Epub ahead of print]
- PMID: 30949688
- PubMed abstract
- Source abstract
-
- Prevalence of germline variants in inflammatory breast cancer.
- Rana HQ, Sacca R, Drogan C, Gutierrez S, Schlosnagle E, Regan MM, Speare V, LaDuca H, Dolinsky J, Garber JE, Overmoyer BA.
- Cancer. 2019 Apr 1. doi: 10.1002/cncr.32062. [Epub ahead of print]
- PMID: 30933323
- PubMed abstract
- Source abstract
-
- Prevalence and characterization of ATM germline mutations in Chinese BRCA1/2-negative breast cancer patients.
- Yang Z, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Zhang J, Xie Y.
- Breast Cancer Res Treat. 2019 Apr;174(3):639-647. doi: 10.1007/s10549-018-05124-5. Epub 2019 Jan 3.
- PMID: 30607632
- PubMed abstract
- Source abstract
-
- Clinical spectrum and pleiotropic nature of CDH1 germline mutations.
- Figueiredo J, Melo S, Carneiro P, Moreira AM, Fernandes MS, Ribeiro AS, Guilford P, Paredes J, Seruca R.
- J Med Genet. 2019 Apr;56(4):199-208. doi: 10.1136/jmedgenet-2018-105807. Epub 2019 Jan 19.
- PMID: 30661051
- PubMed abstract
- Review
- Free Full Text
-
- Breast cancer risk in neurofibromatosis type 1 is a function of the type of NF1 gene mutation: a new genotype-phenotype correlation.
- Frayling IM, Mautner VF, van Minkelen R, Kallionpaa RA, Aktaş S, Baralle D, Ben-Shachar S, Callaway A, Cox H, Eccles DM, Ferkal S, LaDuca H, Lázaro C, Rogers MT, Stuenkel AJ, Summerour P, Varan A, Yap YS, Zehou O, Peltonen J, Evans DG, Wolkenstein P, Upadhyaya M.
- J Med Genet. 2019 Apr;56(4):209-219. doi: 10.1136/jmedgenet-2018-105599. Epub 2018 Dec 10.
- PMID: 30530636
- PubMed abstract
-
- Direct Ex Vivo Observation of Homologous Recombination Defect Reversal After DNA-Damaging Chemotherapy in Patients With Metastatic Breast Cancer.
- Meijer TG, Verkaik NS, van Deurzen CHM, Dubbink HJ, den Toom TD, Sleddens HFBM, De Hoop EO, Dinjens WNM, Kanaar R, van Gent DC, Jager A.
- JCO Precis Oncol. 2019 Dec [2019 Mar 11];3:1-12. doi: 10.1200/PO.18.00268.
- PMID: 35100677
- PubMed abstract
- Source abstract
-
- Clinical Outcomes, Treatment Patterns, and Health Resource Utilization Among Metastatic Breast Cancer Patients with Germline BRCA1/2 Mutation: A Real-World Retrospective Study.
- Quek RGW, Mardekian J.
- Adv Ther. 2019 Mar;36(3):708-720. doi: 10.1007/s12325-018-0867-x. Epub 2019 Jan 17.
- PMID: 30656571
- PubMed abstract
- Source abstract
-
- [A Case of Early-Onset Breast Cancer for Which the Operative Indication for Breast Conservation Was Based on BRCA Genetic Testing].
- Oki T, Sugimoto T, Ogawa M, Dabanaka K, Hanazaki K.
- Gan To Kagaku Ryoho. 2019 Mar;46(3):555-557.
- PMID: 30914612
- PubMed abstract
- Source abstract
-
- E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
- Godwin TD, Kelly ST, Brew TP, Bougen-Zhukov NM, Single AB, Chen A, Stylianou CE, Harris LD, Currie SK, Telford BJ, Beetham HG, Evans GB, Black MA, Guilford PJ.
- Gastric Cancer. 2019 Mar;22(2):273-286. doi: 10.1007/s10120-018-0859-1. Epub 2018 Jul 31.
- PMID: 30066183
- PubMed abstract
-
- BRCA1/BRCA2 mutations in Japanese women with ductal carcinoma in situ.
- Liu Y, Ide Y, Inuzuka M, Tazawa S, Kanada Y, Matsunaga Y, Kuwayama T, Sawada T, Akashi-Tanaka S, Nakamura S.
- Mol Genet Genomic Med. 2019 Mar;7(3):e493. doi: 10.1002/mgg3.493. Epub 2019 Jan 16.
- PMID: 30652428
- PubMed abstract
- Source abstract
-
- The clinical impact of MRI screening for BRCA mutation carriers: the first report in Japan.
- Murakami W, Tozaki M, Nakamura S, Ide Y, Inuzuka M, Hirota Y, Murakami K, Takahama N, Ohgiya Y, Gokan T.
- Breast Cancer. 2019 Feb 28. doi: 10.1007/s12282-019-00955-6. [Epub ahead of print]
- PMID: 30820924
- PubMed abstract
-
- Heterogeneity in risk factors for ductal and lobular breast carcinomas: A case-control study.
- Dianatinasab M, Fararouei M, Daneshi N, Rezaian S, Mohammadianpanah M, Chaman R, Ghiasvand R.
- Int J Cancer. 2019 Feb 4. doi: 10.1002/ijc.32182. [Epub ahead of print]
- PMID: 30719718
- PubMed abstract
- Source abstract
-
- Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population.
- Gallardo-Alvarado LN, Tusié-Luna MT, Tussié-Luna MI, Díaz-Chávez J, Segura YX, Bargallo-Rocha E, Villarreal C, Herrera-Montalvo LA, Herrera-Medina EM, Cantu-de Leon DF.
- BMC Cancer. 2019 Feb 1;19(1):118. doi: 10.1186/s12885-019-5312-2.
- PMID: 30709381
- PubMed abstract
-
- Oestrogen receptor status and survival in women with BRCA2-associated breast cancer.
- Metcalfe K, Lynch HT, Foulkes WD, Tung N, Olopade OI, Eisen A, Lerner-Ellis J, Snyder C, Kim SJ, Sun P, Narod SA.
- Br J Cancer. 2019 Feb;120(4):398-403. doi: 10.1038/s41416-019-0376-y. Epub 2019 Feb 6.
- PMID: 30723304
- PubMed abstract
- Source abstract
-
- Optimise not compromise: The importance of a multidisciplinary breast cancer patient pathway in the era of oncoplastic and reconstructive surgery.
- Strach MC, Prasanna T, Kirova YM, Alran S, O'Toole S, Beith JM, Poortmans P, McNeil CM, Carroll S.
- Crit Rev Oncol Hematol. 2019 Feb;134:10-21. doi: 10.1016/j.critrevonc.2018.11.007. Epub 2018 Nov 30.
- PMID: 30771869
- PubMed abstract
- Source abstract
-
- Subtypes in BRCA-mutated breast cancer.
- Sønderstrup IMH, Jensen MR, Ejlertsen B, Eriksen JO, Gerdes AM, Kruse TA, Larsen MJ, Thomassen M, Lænkholm AV.
- Hum Pathol. 2019 Feb;84:192-201. doi: 10.1016/j.humpath.2018.10.005. Epub 2018 Oct 17.
- PMID: 30342055
- PubMed abstract
- Source abstract
-
- Evaluation of the BRCAness phenotype and its correlations with clinicopathological features in triple-negative breast cancers.
- Tian T, Shan L, Yang W, Zhou X, Shui R.
- Hum Pathol. 2019 Feb;84:231-238. doi: 10.1016/j.humpath.2018.10.004. Epub 2018 Oct 16.
- PMID: 30339969
- PubMed abstract
-
- [Hereditary predisposition to breast cancer (1): genetics].
- Cohen-Haguenauer O.
- Med Sci (Paris). 2019 Feb;35(2):138-151. doi: 10.1051/medsci/2019003. Epub 2019 Feb 18.
- PMID: 30774081
- PubMed abstract
- Source abstract
- Review, [Article in French]
- Free Full Text
-
- Triple-negative breast cancer: the reality in Chile and in Latin America.
- Caglevic C, Anabalón J, Soza C, Milla E, Gaete F, Carrasco AM, Panay S, Gallardo C, Mahave M.
- Ecancermedicalscience. 2019 Jan 22;13:893. doi: 10.3332/ecancer.2019.893. eCollection 2019.
- PMID: 30792810
- PubMed abstract
- Source abstract
-
- Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer.
- Li JY, Jing R, Wei H, Wang M, Xiaowei Q, Liu H, Jian L, Ou JH, Jiang WH, Tian FG, Sheng Y, Li HY, Xu H, Zhang RS, Guan AH, Liu K, Jiang HC, Ren Y, He JJ, Huang W, Liao N, Cai X, Ming J, Ling R, Xu Y, Hu CY, Zhang J, Guo B, Ouyang L, Shuai P, Liu Z, Zhong L, Zeng Z, Zhang T, Xuan Z, Tan X, Liang J, Pan Q, Chen L, Zhang F, Fan LJ, Zhang Y, Yang X, BoLi J, Chen C, Jiang J.
- Int J Cancer. 2019 Jan 15;144(2):281-289. doi: 10.1002/ijc.31601. Epub 2018 Nov 8.
- PMID: 29752822
- PubMed abstract
- Source abstract
-
- Germline TP53 and MSH6 mutations implicated in sporadic triple-negative breast cancer (TNBC): a preliminary study.
- Yi D, Xu L, Luo J, You X, Huang T, Zi Y, Li X, Wang R, Zhong Z, Tang X, Li A, Shi Y, Rao J, Zhang Y, Sang J.
- Hum Genomics. 2019 Jan 10;13(1):4. doi: 10.1186/s40246-018-0186-y.
- PMID: 30630526
- PubMed abstract
-
- Improving outcomes for young women with breast cancer: fertility and childbearing issues.
- [No author given]
- FORCE. XRAYS. 2019 Jan 7.
- Research news
- Free Full Text
ClinicalTrials.gov: Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer (POSITIVE) (NIH. ClinicalTrials.gov.)
-
- Synchronous Ovarian and Breast Cancers with a Novel Variant in BRCA2 Gene: A Case Report.
- Llinás-Quintero N, Cabrera-Florez E, Mendoza-Fandiño G, Matute-Turizo G, Vasquez-Trespalacios EM, Gallón-Villegas LJ.
- Case Rep Oncol Med. 2019 Jan 6;2019:6958952. doi: 10.1155/2019/6958952. eCollection 2019.
- PMID: 30723561
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Germline Mutations in BRCA1 and BRCA2 in Breast Cancer Patients with High Genetic Risk in Turkish Population.
- Geredeli C, Yasar N, Sakin A.
- Int J Breast Cancer. 2019 Jan 1;2019:9645147. doi: 10.1155/2019/9645147. eCollection 2019.
- PMID: 30713775
- PubMed abstract
- Source abstract
-
- Association Between Invasive Lobular Breast Cancer and Mutations in the Mismatch Repair Gene MSH6.
- Evans DG, Howell SJ, Peltonen J.
- JAMA Oncol. 2019 Jan 1;5(1):119-120. doi: 10.1001/jamaoncol.2018.6905.
- PMID: 30629136
- PubMed abstract
- Source abstract
Original research:
Association of Breast and Ovarian Cancers With Predisposition Genes Identified by Large-Scale Sequencing.
- PMID: 30128536
- PubMed abstract
- Source abstract
Letter, Comment:
Association Between Invasive Lobular Breast Cancer and Mutations in the Mismatch Repair Gene MSH6.
- PMID: 30629137
- PubMed abstract
- Source abstract
Letter, Comment:
Association Between Invasive Lobular Breast Cancer and Mutations in the Mismatch Repair Gene MSH6.
- PMID: 30629138
- PubMed abstract
- Source abstract
Letter, Reply:
Association Between Invasive Lobular Breast Cancer and Mutations in the Mismatch Repair Gene MSH6-Reply.
- PMID: 30629139
- PubMed abstract
- Source abstract
-
- Low risk of invasive lobular carcinoma of the breast in carriers of BRCA1 (hereditary breast and ovarian cancer) and TP53 (Li-Fraumeni syndrome) germline mutations.
- Ditchi Y, Broudin C, El Dakdouki Y, Muller M, Lavaud P, Caron O, Lejri D, Baynes C, Mathieu MC, Salleron J, Benusiglio PR.
- Breast J. 2019 Jan;25(1):16-19. doi: 10.1111/tbj.13154. Epub 2018 Nov 9.
- PMID: 30414230
- PubMed abstract
- Source abstract
-
- Clinical and pathologic characteristics of breast cancer patients carrying the c.3481_3491del11 mutation.
- El Tannouri R, Albuisson E, Jonveaux P, Luporsi E.
- Fam Cancer. 2019 Jan;18(1):1-8. doi: 10.1007/s10689-018-0079-1.
- PMID: 29550896
- PubMed abstract
- Source abstract
-
- Treatment patterns, clinical outcomes, health resource utilization, and cost in patients with BRCA-mutated metastatic breast cancer treated in community oncology settings.
- Houts AC, Olufade T, Shenolikar R, Walker MS, Schwartzberg LS.
- Cancer Treat Res Commun. 2019;19:100121. doi: 10.1016/j.ctarc.2019.100121. Epub 2019 Feb 6.
- PMID: 30785027
- PubMed abstract
-
- CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment.
- Luo W, Fedda F, Lynch P, Tan D.
- Front Pharmacol. 2018 Dec 5;9:1421. doi: 10.3389/fphar.2018.01421. eCollection 2018.
- PMID: 30568591
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- BRCA1 Mutations Associated With Increased Risk of Brain Metastases in Breast Cancer: A 1: 2 Matched-pair Analysis.
- Zavitsanos PJ, Wazer DE, Hepel JT, Wang Y, Singh K, Leonard KL.
- Am J Clin Oncol. 2018 Dec;41(12):1252-1256. doi: 10.1097/COC.0000000000000466.
- PMID: 29782359
- PubMed abstract
- Source abstract
-
- A portrait of germline mutation in Brazilian at-risk for hereditary breast cancer.
- de Souza Timoteo AR, Gonçalves AÉMM, Sales LAP, Albuquerque BM, de Souza JES, de Moura PCP, de Aquino MAA, Agnez-Lima LF, Lajus TBP.
- Breast Cancer Res Treat. 2018 Dec;172(3):637-646. doi: 10.1007/s10549-018-4938-0. Epub 2018 Aug 29.
- PMID: 30159786
- PubMed abstract
- Source abstract
-
- Genome-wide DNA methylation assessment of 'BRCA1-like' early-onset breast cancer: Data from the Australian Breast Cancer Family Registry.
- Scott CM, Wong EM, Joo JE, Dugué PA, Jung CH, O'Callaghan N, Dowty J, Giles GG, Hopper JL, Southey MC.
- Exp Mol Pathol. 2018 Dec;105(3):404-410. doi: 10.1016/j.yexmp.2018.11.006. Epub 2018 Nov 10.
- PMID: 30423315
- PubMed abstract
- Source abstract
-
- Landscape of pathogenic variations in a panel of 34 genes and cancer risk estimation from 5131 HBOC families.
- Castéra L, Harter V, Muller E, Krieger S, Goardon N, Ricou A, Rousselin A, Paimparay G, Legros A, Bruet O, Quesnelle C, Domin F, San C, Brault B, Fouillet R, Abadie C, Béra O, Berthet P; French Exome Project Consortium, Frébourg T, Vaur D.
- Genet Med. 2018 Dec;20(12):1677-1686. doi: 10.1038/s41436-018-0005-9. Epub 2018 Jul 10.
- PMID: 29988077
- PubMed abstract
- Source abstract
-
- Clinicopathologic characterization of breast carcinomas in patients with non-BRCA germline mutations: results from a single institution's high-risk population.
- Meiss AE, Thomas M, Modesitt SC, Ring KL, Atkins KA, Mills AM.
- Hum Pathol. 2018 Dec;82:20-31. doi: 10.1016/j.humpath.2018.06.024. Epub 2018 Jun 26.
- PMID: 29958926
- PubMed abstract
- Source abstract
-
- Non-Coding Variants in BRCA1 and BRCA2 Genes: Potential Impact on Breast and Ovarian Cancer Predisposition.
- Santana Dos Santos E, Lallemand F, Burke L, Stoppa-Lyonnet D, Brown M, Caputo SM, Rouleau E.
- Cancers (Basel). 2018 Nov 16;10(11). pii: E453. doi: 10.3390/cancers10110453.
- PMID: 30453575
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- Differential Burden of Rare and Common Variants on Tumor Characteristics, Survival, and Mode of Detection in Breast Cancer.
- Li J, Ugalde-Morales E, Wen WX, Decker B, Eriksson M, Torstensson A, Christensen HN, Dunning AM, Allen J, Luccarini C, Pooley KA, Simard J, Dorling L, Easton DF, Teo SH, Hall P, Czene K.
- Cancer Res. 2018 Nov 1;78(21):6329-6338. doi: 10.1158/0008-5472.CAN-18-1018.
- PMID: 30385609
- PubMed abstract
-
- Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline CDH1 sequence variants.
- Lee K, Krempely K, Roberts ME, Anderson MJ, Carneiro F, Chao E, Dixon K, Figueiredo J, Ghosh R, Huntsman D, Kaurah P, Kesserwan C, Landrith T, Li S, Mensenkamp AR, Oliveira C, Pardo C, Pesaran T, Richardson M, Slavin TP, Spurdle AB, Trapp M, Witkowski L, Yi CS, Zhang L, Plon SE, Schrader KA, Karam R.
- Hum Mutat. 2018 Nov;39(11):1553-1568. doi: 10.1002/humu.23650.
- PMID: 30311375
- PubMed abstract
- Source abstract
-
- The Ethnic-Specific Spectrum of Germline Nucleotide Variants in DNA Damage Response and Repair Genes in Hereditary Breast and Ovarian Cancer Patients of Tatar Descent.
- Brovkina OI, Shigapova L, Chudakova DA, Gordiev MG, Enikeev RF, Druzhkov MO, Khodyrev DS, Shagimardanova EI, Nikitin AG, Gusev OA.
- Front Oncol. 2018 Oct 2;8:421. doi: 10.3389/fonc.2018.00421. eCollection 2018.
- PMID: 30333958
- PubMed abstract
-
- Menopausal Status and Outcomes of BRCA Mutation Carriers with Breast Cancer.
- Carlson K, Chung A, Mirocha J, Donovan C, Estrada S, Siegel E, Giuliano A, Amersi F.
- Am Surg. 2018 Oct 1;84(10):1584-1588.
- PMID: 30747674
- PubMed abstract
- Source abstract
-
- Associations between RAD51D germline mutations and breast cancer risk and survival in BRCA1/2-negative breast cancers.
- Chen X, Li Y, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y.
- Ann Oncol. 2018 Oct 1;29(10):2046-2051. doi: 10.1093/annonc/mdy338.
- PMID: 30165555
- PubMed abstract
- Source abstract
-
- Inherited Breast Cancer in Nigerian Women.
- Zheng Y, Walsh T, Gulsuner S, Casadei S, Lee MK, Ogundiran TO, Ademola A, Falusi AG, Adebamowo CA, Oluwasola AO, Adeoye A, Odetunde A, Babalola CP, Ojengbede OA, Odedina S, Anetor I, Wang S, Huo D, Yoshimatsu TF, Zhang J, Felix GES, King MC, Olopade OI.
- J Clin Oncol. 2018 Oct 1;36(28):2820-2825. doi: 10.1200/JCO.2018.78.3977. Epub 2018 Aug 21.
- PMID: 30130155
- PubMed abstract
- Source abstract
Research News: Inherited breast cancer in Nigerian women. (FORCE XRAYS)
-
- PALB2 germ-line mutations in Russian breast cancer patients: Identification of recurrent alleles and analysis of phenotypic characteristics of the tumors.
- Imyanitov EN, Preobrazhenskaya EV, Shlejkina AY, Sokolenko AP, Anisimova EI, Ivantsov AO, Togo AV.
- Ann Oncol. 2018 Oct;29 Suppl 8:viii76. doi: 10.1093/annonc/mdy270.234.
- PMID: 32138065
- PubMed abstract
- Source abstract
-
- Genetic Markers in Triple-Negative Breast Cancer.
- Sporikova Z, Koudelakova V, Trojanec R, Hajduch M.
- Clin Breast Cancer. 2018 Oct;18(5):e841-e850. doi: 10.1016/j.clbc.2018.07.023. Epub 2018 Aug 4.
- PMID: 30146351
- PubMed abstract
- Source abstract
- Review
- Free Full Text
-
- Impact of BRCA Mutation Status on Survival of Women With Triple-negative Breast Cancer.
- Yadav S, Ladkany R, Yadav D, Alhalabi O, Khaddam S, Isaac D, Cardenas PY, Zakalik D.
- Clin Breast Cancer. 2018 Oct;18(5):e1229-e1235. doi: 10.1016/j.clbc.2017.12.014. Epub 2017 Dec 30.
- PMID: 29402697
- PubMed abstract
- Source abstract
-
- Whole exome sequencing of breast cancer (TNBC) cases from India: association of MSH6 and BRIP1 variants with TNBC risk and oxidative DNA damage.
- Aravind Kumar M, Naushad SM, Narasimgu N, Nagaraju Naik S, Kadali S, Shanker U, Lakshmi Narasu M.
- Mol Biol Rep. 2018 Oct;45(5):1413-1419. doi: 10.1007/s11033-018-4307-4. Epub 2018 Aug 22.
- PMID: 30136158
- PubMed abstract
- Source abstract
-
- Addition of triple negativity of breast cancer as an indicator for germline mutations in predisposing genes increases sensitivity of clinical selection criteria.
- Hoyer J, Vasileiou G, Uebe S, Wunderle M, Kraus C, Fasching PA, Thiel CT, Hartmann A, Beckmann MW, Lux MP, Reis A.
- BMC Cancer. 2018 Sep 26;18(1):926. doi: 10.1186/s12885-018-4821-8.
- PMID: 30257646
- PubMed abstract
-
- Breast cancer brain metastases show increased levels of genomic aberration-based homologous recombination deficiency scores relative to their corresponding primary tumors.
- Diossy M, Reiniger L, Sztupinszki Z, Krzystanek M, Timms KM, Neff C, Solimeno C, Pruss D, Eklund AC, Tóth E, Kiss O, Rusz O, Cserni G, Zombori T, Székely B, Kulka J, Tímár J, Csabai I, Szallasi Z.
- Ann Oncol. 2018 Sep 1;29(9):1948-1954. doi: 10.1093/annonc/mdy216.
- PMID: 29917049
- PubMed abstract
-
- The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers.
- Weigelt B, Bi R, Kumar R, Blecua P, Mandelker DL, Geyer FC, Pareja F, James PA; kConFab Investigators, Couch FJ, Eccles DM, Blows F, Pharoah P, Li A, Selenica P, Lim RS, Jayakumaran G, Waddell N, Shen R, Norton L, Wen HY, Powell SN, Riaz N, Robson ME, Reis-Filho JS, Chenevix-Trench G.
- J Natl Cancer Inst. 2018 Sep 1;110(9):1030-1034. doi: 10.1093/jnci/djy028.
- PMID: 29506079
- PubMed abstract
-
- Imaging Phenotypes in Women at High Risk for Breast Cancer on Mammography, Ultrasound, and Magnetic Resonance Imaging Using the Fifth Edition of the Breast Imaging Reporting and Data System.
- Marino MA, Riedl CC, Bernathova M, Bernhart C, A T Baltzer P, Helbich TH, Pinker K.
- Eur J Radiol. 2018 Sep;106:150-159. doi: 10.1016/j.ejrad.2018.07.026. Epub 2018 Jul 30.
- PMID: 30150038
- PubMed abstract
- Source abstract
-
- Association Between BRCA Status and Triple-Negative Breast Cancer: A Meta-Analysis.
- Chen H, Wu J, Zhang Z, Tang Y, Li X, Liu S, Cao S, Li X.
- Front Pharmacol. 2018 Aug 21;9:909. doi: 10.3389/fphar.2018.00909. eCollection 2018.
- PMID: 30186165
- PubMed abstract
-
- A novel de novo CDH1 germline variant aids in the classification of carboxy-terminal E-cadherin alterations predicted to escape nonsense-mediated mRNA decay.
- Krempely K, Karam R.
- Cold Spring Harb Mol Case Stud. 2018 Aug 1;4(4). pii: a003012. doi: 10.1101/mcs.a003012. Print 2018 Aug.
- PMID: 29798843
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing.
- Shimelis H, LaDuca H, Hu C, Hart SN, Na J, Thomas A, Akinhanmi M, Moore RM, Brauch H, Cox A, Eccles DM, Ewart-Toland A, Fasching PA, Fostira F, Garber J, Godwin AK, Konstantopoulou I, Nevanlinna H, Sharma P, Yannoukakos D, Yao S, Feng BJ, Tippin Davis B, Lilyquist J, Pesaran T, Goldgar DE, Polley EC, Dolinsky JS, Couch FJ.
- J Natl Cancer Inst. 2018 Aug 1;110(8):855-862. doi: 10.1093/jnci/djy106.
- PMID: 30099541
- PubMed abstract
Research news:
New triple-negative breast cancer risk genes identified.
- PMID: 30122618
- PubMed abstract
- Source abstract
Research news: Triple-negative: Genes associated with risk for aggressive breast cancer. (Science Daily)
Research news: Triple-Negative Breast Cancer Risk Linked to Germline Variants in Several Cancer Genes. (Precision Oncology News)
Research news: Study identifies genes associated with risk of triple-negative breast cancer. (FORCE. XRAYS.)
-
- Male secretory breast cancer: case in a 6-year-old boy with a peculiar gene duplication and review of the literature.
- Ghilli M, Mariniello MD, Scatena C, Dosa L, Traficante G, Tamburini A, Caporalini C, Buccoliero AM, Facchini F, Colizzi L, Quattrini Li A, Landucci E, Manca G, Naccarato AG, Caramella D, Favre C, Roncella M.
- Breast Cancer Res Treat. 2018 Aug;170(3):445-454. doi: 10.1007/s10549-018-4772-4. Epub 2018 Apr 3.
- PMID: 29616377
- PubMed abstract
- Source abstract
-
- Prevalence of BRCA1 and BRCA2 Mutations Among High-Risk Saudi Patients With Breast Cancer.
- Abulkhair O, Al Balwi M, Makram O, Alsubaie L, Faris M, Shehata H, Hashim A, Arun B, Saadeddin A, Ibrahim E.
- J Glob Oncol. 2018 Aug;(4):1-9. doi: 10.1200/JGO.18.00066.
- PMID: 30199306
- PubMed abstract
-
- Hereditary lobular breast cancer with an emphasis on E-cadherin genetic defect.
- Corso G, Figueiredo J, La Vecchia C, Veronesi P, Pravettoni G, Macis D, Karam R, Lo Gullo R, Provenzano E, Toesca A, Mazzocco K, Carneiro F, Seruca R, Melo S, Schmitt F, Roviello F, De Scalzi AM, Intra M, Feroce I, De Camilli E, Villardita MG, Trentin C, De Lorenzi F, Bonanni B, Galimberti V.
- J Med Genet. 2018 Jul;55(7):431-441. doi: 10.1136/jmedgenet-2018-105337. Epub 2018 Jun 21.
- PMID: 29929997
- PubMed abstract
- Source abstract
-
- Association of Germline PALB2 Mutation and Response to Platinum-Based Chemotherapy in Metastatic Breast Cancer: A Case Series.
- Isaac D, Karapetyan L, Tamkus D.
- JCO Precis Oncol. 2018 Nov [2018 Jun 26];2:1-5. doi: 10.1200/PO.17.00258.
- PMID: 35135128
- PubMed abstract
- Source abstract
- Case report
- Free Full Text
-
- Orbital Metastases from Breast Cancer with BRCA2 Mutation: A Case Report and Literature Review.
- Barber E, Lyou Y, Mehta R, Lin E, Lane K, Parajuli R.
- Case Rep Oncol. 2018 Jun 7;11(2):360-364. doi: 10.1159/000489698. eCollection 2018 May-Aug.
- PMID: 29983698
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Reparameterization of PAM50 Expression Identifies Novel Breast Tumor Dimensions and Leads to Discovery of a Genome-Wide Significant Breast Cancer Locus at 12q15.
- Madsen MJ, Knight S, Sweeney C, Factor R, Salama M, Stijleman IJ, Rajamanickam V, Welm BE, Arunachalam S, Jones B, Rachamadugu R, Rowe K, Cessna MH, Thomas A, Kushi LH, Caan BJ, Bernard PS, Camp NJ.
- Cancer Epidemiol Biomarkers Prev. 2018 Jun;27(6):644-652. doi: 10.1158/1055-9965.EPI-17-0887. Epub 2018 Apr 12.
- PMID: 29650789
- PubMed abstract
-
- Extent of breast cancer type 1 promoter methylation correlates with clinicopathological features in breast cancers.
- Sun MY, Chang XZ, Xu GY, Dong Y, Zhou ZJ, Liu T, Wang CQ, Li YS.
- J Cancer Res Ther. 2018 Jun;14([9] Supplement):S354-S361. doi: 10.4103/0973-1482.235354.
- PMID: 29970689
- PubMed abstract
- Source abstract
-
- Multicenter cross-sectional screening of the BRCA gene for Chinese high hereditary risk breast cancer populations.
- Wei H, Wang M, Ou J, Jiang W, Tian F, Sheng Y, Li H, Xu H, Zhang R, Guan A, Wang C, Jiang H, Ren Y, He J, Liu J, Huang W, Liao N, Cai X, Ming J, Ling R, Xu Y, Hu C, Zhang J, Guo B, Ouyang L, Shuai P, Liu Z, Zhong L, Jing R, Zeng Z, Zhang M, Zhang T, Xuan Z, Tan X, Liang J, Pan Q, Chen L, Zhang F, Fan L, Zhang Y, Yang X, Li J, Chen C, Jiang J.
- Oncol Lett. 2018 Jun;15(6):9420-9428. doi: 10.3892/ol.2018.8538. Epub 2018 Apr 18.
- PMID: 29805665
- PubMed abstract
- Source abstract
-
- Promoter hypermethylation of p16, BRCA1 and RASSF1A genes in triple-negative breast cancer patients from Serbia.
- Kozomara Z, Supic G, Krivokuca A, Magic Z, Dzodic R, Milovanovic Z, Brankovic-Magic M.
- J BUON. 2018 May-Jun;23(3):684-691.
- PMID: 30003738
- PubMed abstract
- ToC
-
- Accuracy of self-reported family history of cancer, mutation status and tumor characteristics in patients with early onset breast cancer.
- Augustinsson A, Ellberg C, Kristoffersson U, Borg Å, Olsson H.
- Acta Oncol. 2018 May;57(5):595-603. doi: 10.1080/0284186X.2017.1404635. Epub 2017 Nov 22.
- PMID: 29164969
- PubMed abstract
- Source abstract
-
- Triple negative breast cancer: new therapeutic approaches and BRCA status.
- Guney Eskiler G, Cecener G, Egeli U, Tunca B.
- APMIS. 2018 May;126(5):371-379. doi: 10.1111/apm.12836.
- PMID: 29696717
- PubMed abstract
- Source abstract
-
- Identification and analysis of CHEK2 germline mutations in Chinese BRCA1/2-negative breast cancer patients.
- Fan Z, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xu Y, Xie Y.
- Breast Cancer Res Treat. 2018 May;169(1):59-67. doi: 10.1007/s10549-018-4673-6. Epub 2018 Jan 22.
- PMID: 29356917
- PubMed abstract
- Source abstract
-
- Somatic BRCA1 mutations in clinically sporadic breast cancer with medullary histological features.
- Rechsteiner M, Dedes K, Fink D, Pestalozzi B, Sobottka B, Moch H, Wild P, Varga Z.
- J Cancer Res Clin Oncol. 2018 May;144(5):865-874. doi: 10.1007/s00432-018-2609-5. Epub 2018 Feb 17.
- PMID: 29453630
- PubMed abstract
-
- Somatic mutations in early onset luminal breast cancer.
- Encinas G, Sabelnykova VY, de Lyra EC, Hirata Katayama ML, Maistro S, de Vasconcellos Valle PWM, de Lima Pereira GF, Rodrigues LM, de Menezes Pacheco Serio PA, de Gouvêa ACRC, Geyer FC, Basso RA, Pasini FS, Del Pilar Esteves Diz M, Brentani MM, Guedes Sampaio Góes JC, Chammas R, Boutros PC, Koike Folgueira MAA.
- Oncotarget. 2018 Apr 27;9(32):22460-22479. doi: 10.18632/oncotarget.25123. eCollection 2018 Apr 27.
- PMID: 29854292
- PubMed abstract
- Source abstract
-
- Metaplastic breast cancer in a patient with neurofibromatosis type 1 and somatic loss of heterozygosity.
- Suarez-Kelly LP, Akagi K, Reeser JW, Samorodnitsky E, Reeder M, Smith A, Roychowdhury S, Symer DE, Carson WE.
- Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: a002352. doi: 10.1101/mcs.a002352. Print 2018 Apr.
- PMID: 29449315
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Practical consensus recommendations for neo-adjuvant chemotherapy in triple negative breast cancer.
- Bhattacharyya GS, Walia M, Nandi M, Murli A, Salim S, Rajpurohit S, Shinde S, Aggarwal S, Parikh PM.
- South Asian J Cancer. 2018 Apr-Jun;7(2):156-158. doi: 10.4103/sajc.sajc_126_18.
- PMID: 29721485
- PubMed abstract
- Source abstract
-
- Sebaceous carcinoma of the breast in a patient with a pathogenic BRCA2 (886delGT) mutation - focus on histopathologic and immunohistochemical features.
- Acosta AM, Al Rasheed MRH, Xu H, Salibay C, Pins MR.
- APMIS. 2018 Apr;126(4):353-356. doi: 10.1111/apm.12826.
- PMID: 29575201
- PubMed abstract
- Source abstract
-
- Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
- Hauke J, Horvath J, Groß E, Gehrig A, Honisch E, Hackmann K, Schmidt G, Arnold N, Faust U, Sutter C, Hentschel J, Wang-Gohrke S, Smogavec M, Weber BHF, Weber-Lassalle N, Weber-Lassalle K, Borde J, Ernst C, Altmüller J, Volk AE, Thiele H, Hübbel V, Nürnberg P, Keupp K, Versmold B, Pohl E, Kubisch C, Grill S, Paul V, Herold N, Lichey N, Rhiem K, Ditsch N, Ruckert C, Wappenschmidt B, Auber B, Rump A, Niederacher D, Haaf T, Ramser J, Dworniczak B, Engel C, Meindl A, Schmutzler RK, Hahnen E.
- Cancer Med. 2018 Apr;7(4):1349-1358. doi: 10.1002/cam4.1376. Epub 2018 Mar 9.
- PMID: 29522266
- PubMed abstract
- Source abstract
-
- Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan.
- Arai M, Yokoyama S, Watanabe C, Yoshida R, Kita M, Okawa M, Sakurai A, Sekine M, Yotsumoto J, Nomura H, Akama Y, Inuzuka M, Nomizu T, Enomoto T, Nakamura S.
- J Hum Genet. 2018 Apr;63(4):447-457. doi: 10.1038/s10038-017-0355-1. Epub 2017 Nov 8.
- PMID: 29176636
- PubMed abstract
-
- Clinicopathological and Molecular Study of Triple-Negative Breast Cancer in Algerian Patients.
- Gaceb H, Cherbal F, Bakour R, Ould-Rouis A, Mahfouf H.
- Pathol Oncol Res. 2018 Apr;24(2):297-308. doi: 10.1007/s12253-017-0242-2. Epub 2017 May 6.
- PMID: 28478614
- PubMed abstract
- Source abstract
-
- Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history.
- Engel C, Rhiem K, Hahnen E, Loibl S, Weber KE, Seiler S, Zachariae S, Hauke J, Wappenschmidt B, Waha A, Blümcke B, Kiechle M, Meindl A, Niederacher D, Bartram CR, Speiser D, Schlegelberger B, Arnold N, Wieacker P, Leinert E, Gehrig A, Briest S, Kast K, Riess O, Emons G, Weber BHF, Engel J, Schmutzler RK; German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC).
- BMC Cancer. 2018 Mar 7;18(1):265. doi: 10.1186/s12885-018-4029-y.
- PMID: 29514593
- PubMed abstract
-
- Characterization of mutations in BRCA1/2 and the relationship with clinic-pathological features of breast cancer in a hereditarily high-risk sample of chinese population.
- Fang M, Zhu L, Li H, Li X, Wu Y, Wu K, Lin J, Sheng Y, Yu Y.
- Oncol Lett. 2018 Mar;15(3):3068-3074. doi: 10.3892/ol.2017.7717. Epub 2017 Dec 29.
- PMID: 29435039
- PubMed abstract
-
- Genotype-Phenotype Correlations in Breast Cancer.
- Marotti JD, Schnitt SJ.
- Surg Pathol Clin. 2018 Mar;11(1):199-211. doi: 10.1016/j.path.2017.09.008. Epub 2017 Dec 15.
- PMID: 29413657
- PubMed abstract
- Source abstract
-
- Germline BRCA1/BRCA2 mutations among high risk breast cancer patients in Jordan.
- Abdel-Razeq H, Al-Omari A, Zahran F, Arun B.
- BMC Cancer. 2018 Feb 6;18(1):152. doi: 10.1186/s12885-018-4079-1.
- PMID: 29409476
- PubMed abstract
-
- BRCA mutations in women with inflammatory breast cancer.
- Gutierrez Barrera AM, Fouad TM, Song J, Webster R, Elsayegh N, Wood AL, Demir A, Litton JK, Ueno NT, Arun BK.
- Cancer. 2018 Feb 1;124(3):466-474. doi: 10.1002/cncr.31069. Epub 2017 Oct 17.
- PMID: 29044548
- PubMed abstract
- Source abstract
-
- BRCAsearch: written pre-test information and BRCA1/2 germline mutation testing in unselected patients with newly diagnosed breast cancer.
- Nilsson MP, Törngren T, Henriksson K, Kristoffersson U, Kvist A, Silfverberg B, Borg Å, Loman N.
- Breast Cancer Res Treat. 2018 Feb;168(1):117-126. doi: 10.1007/s10549-017-4584-y. Epub 2017 Nov 21.
- PMID: 29164420
- PubMed abstract
-
- Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels.
- Kwong A, Ho JCW, Shin VY, Kurian AW, Tai E, Esserman LJ, Weitzel JN, Lin PH, Field M, Domchek SM, Lo J, Ngan HYS, Ma ESK, Chan TL, Ford JM.
- Oncotarget. 2017 Dec 20;9(8):7832-7843. doi: 10.18632/oncotarget.23471. eCollection 2018 Jan 30.
- PMID: 29487695
- PubMed abstract
- Source abstract
-
- Hereditary diffuse gastric cancer: One family's story.
- Zylberberg HM, Sultan K, Rubin S.
- World J Clin Cases. 2018 Jan 16;6(1):1-5. doi: 10.12998/wjcc.v6.i1.1.
- PMID: 29376063
- PubMed abstract
- Source abstract
- Case report
- Free PMC article
- Free Full Text
-
- Expression of breast cancer type 1 and its relation with expression of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2/neu in breast carcinoma on trucut biopsy specimens.
- Verma D, Agarwal K, Tudu SK.
- Indian J Pathol Microbiol. 2018 Jan-Mar;61(1):31-38. doi: 10.4103/IJPM.IJPM_393_16.
- PMID: 29567881
- PubMed abstract
- Source abstract
-
- Characterization of basal-like subtype in a Danish consecutive primary breast cancer cohort.
- Kinalis S, Nielsen FC, Talman ML, Ejlertsen B, Rossing M.
- Acta Oncol. 2018 Jan;57(1):51-57. doi: 10.1080/0284186X.2017.1398837. Epub 2017 Nov 22.
- PMID: 29164968
- PubMed abstract
- Source abstract
-
- Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG.
- Soenderstrup IMH, Laenkholm AV, Jensen MB, Eriksen JO, Gerdes AM, Hansen TVO, Kruse TA, Larsen MJ, Pedersen IS, Rossing M, Thomassen M, Ejlertsen B.
- Acta Oncol. 2018 Jan;57(1):95-101. doi: 10.1080/0284186X.2017.1398415. Epub 2017 Nov 22.
- PMID: 29164974
- PubMed abstract
- Source abstract
-
- Abnormal Findings Detected by Multi-modality Breast Imaging and Biopsy Results in a High-risk Clinic.
- Laitman Y, Feldman DM, Sklair-Levy M, Yosepovich A, Barshack-Nakar I, Brodsky M, Halshtok O, Shalmon A, Gotlieb M, Friedman E.
- Clin Breast Cancer. 2017 Dec 11. pii: S1526-8209(17)30559-1. doi: 10.1016/j.clbc.2017.12.005. [Epub ahead of print]
- PMID: 29292184
- PubMed abstract
- Source abstract
-
- BRCA1 germline mutations dominate familial breast cancer patients in Henan China.
- Wang L, Zhou S, Xie J, Gao H, Wang F, Zhou J, Wang Y, Wang H.
- J Thorac Dis. 2017 Dec;9(12):5295-5299. doi: 10.21037/jtd.2017.11.71.
- PMID: 29312738
- PubMed abstract
- Source abstract
-
- Breast cancer cases of female patients under 35 years of age in Togo: A series of 158 cases.
- Darré T, Tchaou M, Folligan K, Amadou A, N'Timon B, Sonhaye L, Aboubakari AS, Amégbor K, Akpadza K, Napo Koura G.
- Mol Clin Oncol. 2017 Dec;7(6):1125-1129. doi: 10.3892/mco.2017.1461. Epub 2017 Oct 18.
- PMID: 29285387
- PubMed abstract
- Source abstract
-
- Early onset breast cancer in Ashkenazi women carriers of founder BRCA1/2 mutations: beyond 10 years of follow-up.
- Dagan E, Gershoni-Baruch R, Kurolap A, Fried G.
- Eur J Cancer Care (Engl). 2017 Nov;26(6). doi: 10.1111/ecc.12594. Epub 2016 Oct 10.
- PMID: 27726213
- PubMed abstract
- Source abstract
-
- Clinical and genetic characterization of hereditary breast cancer in a Chinese population.
- Jian W, Shao K, Qin Q, Wang X, Song S, Wang X.
- Hered Cancer Clin Pract. 2017 Oct 30;15:19. doi: 10.1186/s13053-017-0079-4. eCollection 2017.
- PMID: 29093764
- PubMed abstract
-
- The role of BRCA status on prognosis in patients with triple-negative breast cancer.
- Xie Y, Gou Q, Wang Q, Zhong X, Zheng H.
- Oncotarget. 2017 Aug 3;8(50):87151-87162. doi: 10.18632/oncotarget.19895. eCollection 2017 Oct 20.
- PMID: 29152070
- PubMed abstract
- Source abstract
-
- Hypoxia-induced factor-1 alpha, vascular endothelial growth factor expression in BRCA1-related breast cancer: A prospective study in tertiary care hospital.
- Sharma M, Piplani S, Madan M, Manjari M, Garg S, Kaur K.
- Indian J Pathol Microbiol. 2017 Oct-Dec;60(4):469-474. doi: 10.4103/IJPM.IJPM_524_16.
- PMID: 29323057
- PubMed abstract
- Source abstract
-
- Association of BRCA Mutation Types, Imaging Features, and Pathologic Findings in Patients With Breast Cancer With BRCA1 and BRCA2 Mutations.
- Ha SM, Chae EY, Cha JH, Kim HH, Shin HJ, Choi WJ.
- AJR Am J Roentgenol. 2017 Oct;209(4):920-928. doi: 10.2214/AJR.16.16957. Epub 2017 Aug 10.
- PMID: 28796549
- PubMed abstract
- Source abstract
-
- BRCA related breast cancer and sporadic tumors: same prognosis or survivorship bias?
- Ballatore Z, Bracci R, Bianchi F, Maccaroni E, Belvederesi L, Brugiati C, Murrone A, Pagliaretta S, Pistelli M, Berardi R.
- Ann Oncol. 2017 Oct;28 Suppl 6:vi28. doi: 10.1093/annonc/mdx424.011.
- PMID: 31962651
- PubMed abstract
- Conference abstract
- Free Full Text
-
- BRCA1/BRCA2 mutations in a Mediterranean population (Apulia Region) with breast or ovarian cancer: a single center experience.
- Caloro M, Orlando L, Lutrino ES, Quaranta A, Caliolo C, Schiavone P, Aprile G, Chetrì MC, D'Amico M, Rizzo P, Fedele P, Loparco D, Mazzoni E, Marino A, Calvani N, Sponziello F, Nacci A, Cinefra M, Ferrara P, Cinieri S.
- Ann Oncol. 2017 Oct;28 Suppl 6:vi32. doi: 10.1093/annonc/mdx424.025.
- PMID: 31962667
- PubMed abstract
- Conference abstract
- Free Full Text
-
- Pathogenetic mutations in BRCA related triple negative breast cancer.
- Bini F, Ballatore Z, Bianchi F, Maccaroni E, Belvederesi L, Brugiati C, Pagliaretta S, Murrone A, Savini A, Pistelli M, Bracci R, Berardi R.
- Ann Oncol. 2017 Oct;28 Suppl 6:vi34-vi35. doi: 10.1093/annonc/mdx424.034.
- PMID: 31962676
- PubMed abstract
- Conference abstract
- Free Full Text
-
- Prevalence and spectrum of germline rare variants in BRCA1/2 and PALB2 among breast cancer cases in Sarawak, Malaysia.
- Yang XR, Devi BCR, Sung H, Guida J, Mucaki EJ, Xiao Y, Best A, Garland L, Xie Y, Hu N, Rodriguez-Herrera M, Wang C, Jones K, Luo W, Hicks B, Tang TS, Moitra K, Rogan PK, Dean M.
- Breast Cancer Res Treat. 2017 Oct;165(3):687-697. doi: 10.1007/s10549-017-4356-8. Epub 2017 Jun 29.
- PMID: 28664506
- PubMed abstract
- Source abstract
-
- Multi-institutional Evaluation of Women at High Risk of Developing Breast Cancer.
- Hermel DJ, Wood ME, Chun J, Rounds T, Sands M, Schwartz S, Schnabel FR.
- Clin Breast Cancer. 2017 Oct;17(6):427-432. doi: 10.1016/j.clbc.2017.04.005. Epub 2017 Apr 14.
- PMID: 28539235
- PubMed abstract
- Source abstract
-
- Molecular characterization and clinical interpretation of BRCA1/BRCA2 variants in families from Murcia (south-eastern Spain) with hereditary breast and ovarian cancer: clinical-pathological features in BRCA carriers and non-carriers.
- Gabaldó Barrios X, Sarabia Meseguer MD, Marín Vera M, Sánchez Bermúdez AI, Macías Cerrolaza JA, Sánchez Henarejos P, Zafra Poves M, García Hernández MR, Cuevas Tortosa E, Aliaga Baño Á, Castillo Guardiola V, Martínez Hernández P, Tovar Zapata I, Martínez Barba E, Ayala de la Peña F, Alonso Romero JL, Noguera Velasco JA, Ruiz Espejo F.
- Fam Cancer. 2017 Oct;16(4):477-489. doi: 10.1007/s10689-017-9985-x.
- PMID: 28477318
- PubMed abstract
- Source abstract
-
- ATM, radiation, and the risk of second primary breast cancer.
- Bernstein JL; WECARE Study Collaborative Group, Concannon P.
- Int J Radiat Biol. 2017 Oct;93(10):1121-1127. doi: 10.1080/09553002.2017.1344363. Epub 2017 Jul 27.
- PMID: 28627265
- PubMed abstract
- Source abstract
- Review
- Free PMC article
-
- Analysis of BRCA1/2 mutation spectrum and prevalence in unselected Chinese breast cancer patients by next-generation sequencing.
- Li G, Guo X, Tang L, Chen M, Luo X, Peng L, Xu X, Wang S, Xiao Z, Yi W, Dai L, Wang J.
- J Cancer Res Clin Oncol. 2017 Oct;143(10):2011-2024. doi: 10.1007/s00432-017-2465-8. Epub 2017 Jun 29.
- PMID: 28664449
- PubMed abstract
- Source abstract
-
- A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.
- Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA, Laird PW, Shen H, Ellisen LW, D'Andrea AD, Chanock SJ, Foulkes WD, Getz G.
- Nat Genet. 2017 Oct;49(10):1476-1486. doi: 10.1038/ng.3934. Epub 2017 Aug 21.
- PMID: 28825726
- PubMed abstract
- Source abstract
-
- Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma.
- Thibodeau ML, Reisle C, Zhao E, Martin LA, Alwelaie Y, Mungall KL, Ch'ng C, Thomas R, Ng T, Yip S, Lim H, Sun S, Young SS, Karsan A, Zhao Y, Mungall AJ, Moore RA, Renouf D, Gelmon K, Ma YP, Hayes M, Laskin J, Marra MA, Schrader KA, Jones SJM.
- Cold Spring Harb Mol Case Stud. 2017 Sep 1;3(5). pii: a001628. doi: 10.1101/mcs.a001628. Print 2017 Sep.
- PMID: 28514723
- PubMed abstract
- Source abstract
- Case report
- Free Full Text
-
- Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer.
- Elimam AA, Aabdein MEMM, Eldeen MEM, Altayb HN, Taha MA, Nimir MN, Dafaalla MD, Alfaki MM, Abdelrahim MA, Abdalla AA, Mohammed MI, Ellaithi M, Hamid MMA, Hassan MAS.
- BMC Med Genet. 2017 Aug 16;18(1):85. doi: 10.1186/s12881-017-0448-x.
- PMID: 28814288
- PubMed abstract
-
- Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53.
- Lolas Hamameh S, Renbaum P, Kamal L, Dweik D, Salahat M, Jaraysa T, Abu Rayyan A, Casadei S, Mandell JB, Gulsuner S, Lee MK, Walsh T, King MC, Levy-Lahad E, Kanaan M.
- Int J Cancer. 2017 Aug 15;141(4):750-756. doi: 10.1002/ijc.30771. Epub 2017 May 19.
- PMID: 28486781
- PubMed abstract
- Source abstract
-
- Breast Cancer Survival of BRCA1/BRCA2 Mutation Carriers in a Hospital-Based Cohort of Young Women.
- Schmidt MK, van den Broek AJ, Tollenaar RA, Smit VT, Westenend PJ, Brinkhuis M, Oosterhuis WJ, Wesseling J, Janssen-Heijnen ML, Jobsen JJ, Jager A, Voogd AC, van Leeuwen FE, van 't Veer LJ.
- J Natl Cancer Inst. 2017 Aug 1;109(8). doi: 10.1093/jnci/djw329.
- PMID: 28376189
- PubMed abstract
- Source abstract
-
- Hormone receptor status of a first primary breast cancer predicts contralateral breast cancer risk in the WECARE study population.
- Reiner AS, Lynch CF, Sisti JS, John EM, Brooks JD, Bernstein L, Knight JA, Hsu L, Concannon P, Mellemkjær L, Tischkowitz M, Haile RW, Shen R, Malone KE, Woods M, Liang X, Morrow M, Bernstein JL; WECARE Study Collaborative Group.
- Breast Cancer Res. 2017 Jul 19;19(1):83. doi: 10.1186/s13058-017-0874-x.
- PMID: 28724391
- PubMed abstract
-
- Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients.
- Sun J, Meng H, Yao L, Lv M, Bai J, Zhang J, Wang L, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y.
- Clin Cancer Res. 2017 Jul 19. pii: clincanres.3227.2016. doi: 10.1158/1078-0432.CCR-16-3227. [Epub ahead of print]
- PMID: 28724667
- PubMed abstract
- Source abstract
-
- Ductal Carcinoma in situ Detected during Prospective MR Imaging Screening of a Woman with a BRCA2 Mutation: The First Case Report in Japan.
- Tozaki M, Nakamura S, Kitagawa D, Iwase T, Horii R, Akiyama F, Arai M.
- Magn Reson Med Sci. 2017 Jul 10;16(3):265-269. doi: 10.2463/mrms.cr.2016-0090. Epub 2017 Jan 13.
- PMID: 28090007
- PubMed abstract
- Source abstract
- Case Report
- Free Full Text (PDF)
-
- Assessment of Breast Cancer Risk Factors Reveals Subtype Heterogeneity.
- Holm J, Eriksson L, Ploner A, Eriksson M, Rantalainen M, Li J, Hall P, Czene K.
- Cancer Res. 2017 Jul 1;77(13):3708-3717. doi: 10.1158/0008-5472.CAN-16-2574. Epub 2017 May 16.
- PMID: 28512241
- PubMed abstract
- Source abstract
-
- The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing.
- Lang GT, Shi JX, Hu X, Zhang CH, Shan L, Song CG, Zhuang ZG, Cao AY, Ling H, Yu KD, Shan L, Sun MH, Zhou XY, Huang W, Shao ZM.
- Int J Cancer. 2017 Jul 1;141(1):129-142. doi: 10.1002/ijc.30692. Epub 2017 Apr 25.
- PMID: 28294317
- PubMed abstract
- Source abstract
-
- Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers.
- Grindedal EM, Heramb C, Karsrud I, Ariansen SL, Mæhle L, Undlien DE, Norum J, Schlichting E.
- BMC Cancer. 2017 Jun 21;17(1):438. doi: 10.1186/s12885-017-3422-2.
- PMID: 28637432
- PubMed abstract
-
- Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers.
- Krammer J, Pinker-Domenig K, Robson ME, Gönen M, Bernard-Davila B, Morris EA, Mangino DA, Jochelson MS.
- Breast Cancer Res Treat. 2017 Jun;163(3):565-571. doi: 10.1007/s10549-017-4198-4. Epub 2017 Mar 25.
- PMID: 28343309
- PubMed abstract
- Source abstract
-
- Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer.
- Krüger K, Wik E, Knutsvik G, Nalwoga H, Klingen TA, Arnes JB, Chen Y, Mannelqvist M, Dimitrakopoulou K, Stefansson IM, Birkeland E, Aas T, Tobin NP, Jonassen I, Bergh J, Foulkes WD, Akslen LA.
- Sci Rep. 2017 Apr 24;7(1):1089. doi: 10.1038/s41598-017-00862-w.
- PMID: 28439082
- PubMed abstract
-
- Examining the common aetiology of serous ovarian cancers and basal-like breast cancers using double primaries.
- Begg CB, Rice MS, Zabor EC, Tworoger SS.
- Br J Cancer. 2017 Apr 11;116(8):1088-1091. doi: 10.1038/bjc.2017.73. Epub 2017 Mar 23.
- PMID: 28334730
- PubMed abstract
- Source abstract
-
- Risk algorithms that include pathology adjustment for HER2 amplification need to make further downward adjustments in likelihood scores.
- Evans DG, Woodward ER, Howell SJ, Verhoef S, Howell A, Lalloo F.
- Fam Cancer. 2017 Apr;16(2):173-179. doi: 10.1007/s10689-016-9942-0.
- PMID: 27796713
- PubMed abstract
-
- Identification of recurrent BRCA1 mutation and its clinical relevance in Chinese Triple-negative breast cancer cohort.
- Liu X, Li H, Shao B, Wu J, Kong W, Song G, Jiang H, Wang J, Wan F.
- Cancer Med. 2017 Mar;6(3):547-554. doi: 10.1002/cam4.1004. Epub 2017 Jan 30.
- PMID: 28135048
- PubMed abstract
- Source abstract
-
- The impact of reproductive life on breast cancer risk in women with family history or BRCA mutation.
- Toss A, Grandi G, Cagnacci A, Marcheselli L, Pavesi S, De Matteis E, Razzaboni E, Tomasello C, Cascinu S, Cortesi L.
- Oncotarget. 2017 Feb 7;8(6):9144-9154. doi: 10.18632/oncotarget.13423.
- PMID: 27880720
- PubMed abstract
- Source abstract
-
- Carcinosarcoma of the Breast: An Aggressive Subtype of Metaplastic Cancer. Report of a Rare Case in a Young BRCA-1 Mutated Woman.
- Ghilli M, Mariniello DM, Fanelli G, Cascione F, Fontana A, Cristaudo A, Cilotti A, Caligo AM, Manca G, Colizzi L, Naccarato AG, Roncella M.
- Clin Breast Cancer. 2017 Feb;17(1):e31-e35. doi: 10.1016/j.clbc.2016.08.002. Epub 2016 Aug 30.
- PMID: 27697421
- PubMed abstract
- Source abstract
-
- Genetic and epigenetic characterization of the BRCA1 gene in Brazilian women at-risk for hereditary breast cancer.
- Felicio PS, Melendez ME, Arantes LM, Kerr LM, Carraro DM, Grasel RS, Campacci N, Scapulatempo-Neto C, Fernandes GC, de Carvalho AC, Palmero EI.
- Oncotarget. 2017 Jan 10;8(2):2850-2862. doi: 10.18632/oncotarget.13750.
- PMID: 27926510
- PubMed abstract
- Source abstract
-
- Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family.
- Geyer FC, Berman SH, Marchiò C, Burke KA, Guerini-Rocco E, Piscuoglio S, Ng CK, Pareja F, Wen HY, Hodi Z, Schnitt SJ, Rakha EA, Ellis IO, Norton L, Weigelt B, Reis-Filho JS.
- Mod Pathol. 2017 Jan;30(1):69-84. doi: 10.1038/modpathol.2016.161. Epub 2016 Oct 7.
- PMID: 27713419
- PubMed abstract
- Source abstract
-
- Clinical Characteristics in Patients with Triple Negative Breast Cancer.
- Yeh J, Chun J, Schwartz S, Wang A, Kern E, Guth AA, Axelrod D, Shapiro R, Schnabel F.
- Int J Breast Cancer. 2017;2017:1796145. doi: 10.1155/2017/1796145. Epub 2017 Aug 17.
- PMID: 28912973
- PubMed abstract
-
- BRCAness as a Biomarker for Predicting Prognosis and Response to Anthracycline-Based Adjuvant Chemotherapy for Patients with Triple-Negative Breast Cancer.
- Mori H, Kubo M, Nishimura R, Osako T, Arima N, Okumura Y, Okido M, Yamada M, Kai M, Kishimoto J, Miyazaki T, Oda Y, Otsuka T, Nakamura M.
- PLoS One. 2016 Dec 15;11(12):e0167016. doi: 10.1371/journal.pone.0167016. eCollection 2016.
- PMID: 27977696
- PubMed abstract
-
- Tumor characteristics and prognosis in familial breast cancer.
- Arpino G, Pensabene M, Condello C, Ruocco R, Cerillo I, Lauria R, Forestieri V, Giuliano M, De Angelis C, Montella M, Crispo A, De Placido S.
- BMC Cancer. 2016 Nov 29;16(1):924.
- PMID: 27899083
- PubMed abstract
-
- FOXC1 identifies basal-like breast cancer in a hereditary breast cancer cohort.
- Johnson J, Choi M, Dadmanesh F, Han B, Qu Y, Yu-Rice Y, Zhang X, Bagaria S, Taylor C, Giuliano AE, Amersi F, Cui X.
- Oncotarget. 2016 Nov 15;7(46):75729-75738. doi: 10.18632/oncotarget.12370.
- PMID: 27708239
- PubMed abstract
- Source abstract
-
- Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.
- Muranen TA, Blomqvist C, Dörk T, Jakubowska A, Heikkilä P, Fagerholm R, Greco D, Aittomäki K, Bojesen SE, Shah M, Dunning AM, Rhenius V, Hall P, Czene K, Brand JS, Darabi H, Chang-Claude J, Rudolph A, Nordestgaard BG, Couch FJ, Hart SN, Figueroa J, García-Closas M, Fasching PA, Beckmann MW, Li J, Liu J, Andrulis IL, Winqvist R, Pylkäs K, Mannermaa A, Kataja V, Lindblom A, Margolin S, Lubinski J, Dubrowinskaja N, Bolla MK, Dennis J, Michailidou K, Wang Q, Easton DF, Pharoah PD, Schmidt MK, Nevanlinna H.
- Breast Cancer Res. 2016 Oct 3;18(1):98. doi: 10.1186/s13058-016-0758-5.
- PMID: 27716369
- PubMed abstract
-
- Association between basal-like phenotype and BRCA1/2 germline mutations in Korean breast cancer patients.
- Jung J, Kang E, Gwak JM, Seo AN, Park SY, Lee AS, Baek H, Chae S, Kim EK, Kim SW.
- Curr Oncol. 2016 Oct;23(5):298-303. Epub 2016 Oct 25.
- PMID: 27803593
- PubMed abstract
- Source abstract
-
- Genetic predisposition to gastric cancer.
- Petrovchich I, Ford JM.
- Semin Oncol. 2016 Oct;43(5):554-559. doi: 10.1053/j.seminoncol.2016.08.006. Epub 2016 Sep 22.
- PMID: 27899187
- PubMed abstract
- Source abstract
-
- [Breast cancer in BRCA1/2 mutation carriers].
- Fabian P, Nenutil R.
- Cesk Patol. 2016 Fall;52(4):206-209.
- PMID: 27869445
- PubMed abstract
- Source abstract (PDF)
- Review, [Article in Czech]
- Table of Contents
-
- High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients.
- Rashid MU, Muhammad N, Bajwa S, Faisal S, Tahseen M, Bermejo JL, Amin A, Loya A, Hamann U.
- BMC Cancer. 2016 Aug 23;16(1):673. doi: 10.1186/s12885-016-2698-y.
- PMID: 27553291
- PubMed abstract
-
- Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.
- Schmidt MK, Hogervorst F, van Hien R, Cornelissen S, Broeks A, Adank MA, Meijers H, Waisfisz Q, Hollestelle A, Schutte M, van den Ouweland A, Hooning M, Andrulis IL, Anton-Culver H, Antonenkova NN, Antoniou AC, Arndt V, Bermisheva M, Bogdanova NV, Bolla MK, Brauch H, Brenner H, Brüning T, Burwinkel B, Chang-Claude J, Chenevix-Trench G, Couch FJ, Cox A, Cross SS, Czene K, Dunning AM, Fasching PA, Figueroa J, Fletcher O, Flyger H, Galle E, García-Closas M, Giles GG, Haeberle L, Hall P, Hillemanns P, Hopper JL, Jakubowska A, John EM, Jones M, Khusnutdinova E, Knight JA, Kosma VM, Kristensen V, Lee A, Lindblom A, Lubinski J, Mannermaa A, Margolin S, Meindl A, Milne RL, Muranen TA, Newcomb PA, Offit K, Park-Simon TW, Peto J, Pharoah PD, Robson M, Rudolph A, Sawyer EJ, Schmutzler RK, Seynaeve C, Soens J, Southey MC, Spurdle AB, Surowy H, Swerdlow A, Tollenaar RA, Tomlinson I, Trentham-Dietz A, Vachon C, Wang Q, Whittemore AS, Ziogas A, van der Kolk L, Nevanlinna H, Dörk T, Bojesen S, Easton DF.
- J Clin Oncol. 2016 Aug 10;34(23):2750-60. doi: 10.1200/JCO.2016.66.5844. Epub 2016 Jun 6.
- PMID: 27269948
- PubMed abstract
- Source abstract
-
- Long-term survival and BRCA status in male breast cancer: a retrospective single-center analysis.
- Gargiulo P, Pensabene M, Milano M, Arpino G, Giuliano M, Forestieri V, Condello C, Lauria R, De Placido S.
- BMC Cancer. 2016 Jul 4;16(1):375.
- PMID: 27377827
- PubMed abstract
-
- Common genetic susceptibility to DCIS and invasive ductal carcinoma.
- Sopik V, Narod SA.
- Breast Cancer Res. 2016 Jun 10;18(1):60. doi: 10.1186/s13058-016-0719-z.
- PMID: 27286830
- PubMed abstract
- Letter
- Free PMC article
- Free Full Text
Genetic predisposition to ductal carcinoma in situ of the breast.
- PMID: 26884359
- PubMed abstract
-
- [BRCA1/2 gene mutation and clinicopathologic features of triple negative breast cancer].
- Ma ZP, Wang W, Zhang W.
- Zhonghua Bing Li Xue Za Zhi. 2016 Jun 8;45(6):397-400. doi: 10.3760/cma.j.issn.0529-5807.2016.06.009.
- PMID: 27256048
- PubMed abstract
- Source abstract
-
- Importance of hereditary and selected environmental risk factors in the etiology of inflammatory breast cancer: a case-comparison study.
- Moslehi R, Freedman E, Zeinomar N, Veneroso C, Levine PH.
- BMC Cancer. 2016 May 26;16(1):334. doi: 10.1186/s12885-016-2369-z.
- PMID: 27229687
- PubMed abstract
-
- Triple negative status and BRCA mutations in contralateral breast cancer: a population-based study.
- Pellegrino B, Bella M, Michiara M, Zanelli P, Naldi N, Porzio R, Bortesi B, Boggiani D, Zanoni D, Camisa R, Neri TM, Pinto C, Musolino A.
- Acta Biomed. 2016 May 6;87(1):54-63.
- PMID: 27163896
- PubMed abstract
- Source abstract
-
- Evaluation of BRCAPRO Risk Assessment Model in Patients with Ductal Carcinoma In situ Who Underwent Clinical BRCA Genetic Testing.
- Elsayegh N, Barrera AM, Muse KI, Lin H, Kuerer HM, Helm M, Litton JK, Arun BK.
- Front Genet. 2016 Apr 27;7:71. doi: 10.3389/fgene.2016.00071. eCollection 2016.
- PMID: 27200080
- PubMed abstract
-
- Twenty-one-gene recurrence score assay in BRCA-associated versus sporadic breast cancers: Differences based on germline mutation status.
- Shah PD, Patil S, Dickler MN, Offit K, Hudis CA, Robson ME.
- Cancer. 2016 Apr 15;122(8):1178-1184. doi: 10.1002/cncr.29903. Epub 2016 Feb 9.
- PMID: 26859126
- PubMed abstract
- Source abstract
-
- Frequency of germline DNA genetic findings in an unselected prospective cohort of triple-negative breast cancer patients participating in a platinum-based neoadjuvant chemotherapy trial.
- González-Rivera M, Lobo M, López-Tarruella S, Jerez Y, Del Monte-Millán M, Massarrah T, Ramos-Medina R, Ocaña I, Picornell A, Garzón SS, Pérez-Carbornero L, García-Saenz JA, Gómez H, Moreno F, Márquez-Rodas I, Fuentes H, Martin M.
- Breast Cancer Res Treat. 2016 Apr;156(3):507-15. doi: 10.1007/s10549-016-3792-1. Epub 2016 Apr 15.
- PMID: 27083178
- PubMed abstract
- Source abstract
-
- Development of a novel PTT assay for mutation detection in PALB2 large exons and PALB2 screening in medullary breast cancer.
- Poumpouridou N, Goutas N, Tsionou C, Dimas K, Lianidou E, Kroupis C.
- Fam Cancer. 2016 Apr;15(2):183-91. doi: 10.1007/s10689-015-9851-7.
- PMID: 26573693
- PubMed abstract
- Source abstract
-
- Increased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival.
- Thike AA, Tan PH, Ikeda M, Iqbal J.
- Histopathology. 2016 Apr;68(5):702-12. doi: 10.1111/his.12801. Epub 2015 Nov 2.
- PMID: 26259780
- PubMed abstract
- Source abstract
-
- BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer.
- Sedic M, Kuperwasser C.
- Cell Cycle. 2016 Mar 3;15(5):621-7. doi: 10.1080/15384101.2016.1141841.
- PMID: 26822887
- PubMed abstract
- Source abstract
-
- Occult Histopathology and Its Predictors in Contralateral and Bilateral Prophylactic Mastectomies.
- Mattos D, Gfrerer L, Ling IT, Reish RG, Hughes KS, Halpern EF, Cetrulo C, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG Jr, Liao EC.
- Ann Surg Oncol. 2016 Mar;23(3):767-75. doi: 10.1245/s10434-015-4896-2. Epub 2015 Nov 17.
- PMID: 26577123
- PubMed abstract
- Source abstract
-
- Genetic predisposition to ductal carcinoma in situ of the breast.
- Petridis C, Brook MN, Shah V, Kohut K, Gorman P, Caneppele M, Levi D, Papouli E, Orr N, Cox A, Cross SS, Dos-Santos-Silva I, Peto J, Swerdlow A, Schoemaker MJ, Bolla MK, Wang Q, Dennis J, Michailidou K, Benitez J, González-Neira A, Tessier DC, Vincent D, Li J, Figueroa J, Kristensen V, Borresen-Dale AL, Soucy P, Simard J, Milne RL, Giles GG, Margolin S, Lindblom A, Brüning T, Brauch H, Southey MC, Hopper JL, Dörk T, Bogdanova NV, Kabisch M, Hamann U, Schmutzler RK, Meindl A, Brenner H, Arndt V, Winqvist R, Pylkäs K, Fasching PA, Beckmann MW, Lubinski J, Jakubowska A, Mulligan AM, Andrulis IL, Tollenaar RA, Devilee P, Le Marchand L, Haiman CA, Mannermaa A, Kosma VM, Radice P, Peterlongo P, Marme F, Burwinkel B, van Deurzen CH, Hollestelle A, Miller N, Kerin MJ, Lambrechts D, Floris G, Wesseling J, Flyger H, Bojesen SE, Yao S, Ambrosone CB, Chenevix-Trench G, Truong T, Guénel P, Rudolph A, Chang-Claude J, Nevanlinna H, Blomqvist C, Czene K, Brand JS, Olson JE, Couch FJ, Dunning AM, Hall P, Easton DF, Pharoah PD, Pinder SE, Schmidt MK, Tomlinson I, Roylance R, García-Closas M, Sawyer EJ.
- Breast Cancer Res. 2016 Feb 17;18(1):22. doi: 10.1186/s13058-016-0675-7.
- PMID: 26884359
- PubMed abstract
Letter
Common genetic susceptibility to DCIS and invasive ductal carcinoma.
- PMID: 27286830
- PubMed abstract
-
- Triple-Negative versus Non-Triple-Negative Breast Cancers in High-Risk Women: Phenotype Features and Survival from the HIBCRIT-1 MRI-Including Screening Study.
- Podo F, Santoro F, Di Leo G, Manoukian S, de Giacomi C, Corcione S, Cortesi L, Carbonaro LA, Trimboli RM, Cilotti A, Preda L, Bonanni B, Pensabene M, Martincich L, Savarese A, Contegiacomo A, Sardanelli F.
- Clin Cancer Res. 2016 Feb 15;22(4):895-904. doi: 10.1158/1078-0432.CCR-15-0459. Epub 2015 Oct 26.
- PMID: 26503945
- PubMed abstract
- Source abstract
-
- Associations of Breast Cancer Risk Prediction Tools With Tumor Characteristics and Metastasis.
- Holm J, Li J, Darabi H, Eklund M, Eriksson M, Humphreys K, Hall P, Czene K.
- J Clin Oncol. 2016 Jan 20;34(3):251-8. doi: 10.1200/JCO.2015.63.0624. Epub 2015 Nov 30.
- PMID: 26628467
- PubMed abstract
- Source abstract
-
- Association of polymorphisms with a family history of cancer and the presence of germline mutations in the BRCA1/BRCA2 genes.
- Fernandes GC, Michelli RA, Scapulatempo-Neto C, Palmero EI.
- Hered Cancer Clin Pract. 2016 Jan 13;14:2. doi: 10.1186/s13053-015-0042-1. eCollection 2016.
- PMID: 26770289
- PubMed abstract
-
- A Case of Metaplastic Breast Cancer with Prolonged Response to Single Agent Liposomal Doxorubicin.
- Hamad L, Khoury T, Vona K, Nestico J, Opyrchal M, Salerno KE.
- Cureus. 2016 Jan 11;8(1):e454. doi: 10.7759/cureus.454.
- PMID: 26918222
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- First description of a sporadic breast cancer in a woman with BRCA1 germline mutation.
- Curtit E, Benhamo V, Gruel N, Popova T, Manie E, Cottu P, Mariani O, Stoppa-Lyonnet D, Pivot X, Stern MH, Vincent-Salomon A.
- Oncotarget. 2015 Nov 3;6(34):35616-24. doi: 10.18632/oncotarget.5348.
- PMID: 26426992
- PubMed abstract
- Source abstract
-
- DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3.
- Yang RL, Mick R, Lee K, Graves HL, Nathanson KL, Domchek SM, Kelz RR, Zhang PJ, Czerniecki BJ.
- J Transl Med. 2015 Oct 24;13(1):335. doi: 10.1186/s12967-015-0698-3.
- PMID: 26496879
- PubMed abstract
-
- High incidence of germline BRCA mutation in patients with ER low-positive/PR low-positive/HER-2 neu negative tumors.
- Sanford RA, Song J, Gutierrez-Barrera AM, Profato J, Woodson A, Litton JK, Bedrosian I, Albarracin CT, Valero V, Arun B.
- Cancer. 2015 Oct 1;121(19):3422-3427. doi: 10.1002/cncr.29572. Epub 2015 Aug 17.
- PMID: 26280679
- PubMed abstract
- Source abstract
Comments on NSGC Discussion Forum Cancer SIG
-
- BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.
- Severson TM, Peeters J, Majewski I, Michaut M, Bosma A, Schouten PC, Chin SF, Pereira B, Goldgraben MA, Bismeijer T, Kluin RJ, Muris JJ, Jirström K, Kerkhoven RM, Wessels L, Caldas C, Bernards R, Simon IM, Linn S.
- Mol Oncol. 2015 Oct;9(8):1528-38. doi: 10.1016/j.molonc.2015.04.011. Epub 2015 May 7.
- PMID: 26004083
- PubMed abstract
- Source abstract
-
- Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-κB Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers.
- Widschwendter M, Burnell M, Fraser L, Rosenthal AN, Philpott S, Reisel D, Dubeau L, Cline M, Pan Y, Yi PC, Gareth Evans D, Jacobs IJ, Menon U, Wood CE, Dougall WC.
- EBioMedicine. 2015 Sep 9;2(10):1331-9. doi: 10.1016/j.ebiom.2015.08.037. eCollection 2015.
- PMID: 26629528
- PubMed abstract
- Source abstract
Commentary
RANKL/OPG in Breast Cancer - Extending Its Territory to BRCA Mutation Carriers.
- PMID: 26629502
- PubMed abstract
- Source abstract
-
- BRCA1 mislocalization associated with breast carcinogenesis and poor prognosis in Taiwanese women.
- Ho JY, Hsu RJ, Wu CL, Chen SH, Wu MY, Yu JC, Gao HW, Yen AM, Chen HH, Yu CP.
- Eur J Cancer Prev. 2015 Sep;24(5):407-15. doi: 10.1097/CEJ.0000000000000114.
- PMID: 25622084
- PubMed abstract
- Source abstract
-
- Fibroadenoma with an unexpected lobular carcinoma in situ: A case report and review of the literature.
- Hua B, Xu JY, Jiang L, Wang Z.
- Oncol Lett. 2015 Sep;10(3):1397-1401. Epub 2015 Jul 14.
- PMID: 26622680
- PubMed abstract
- Source abstract
- Case report, Review
- Free PMC article
- Free Full Text
-
- Mammographic density and breast cancer in women from high risk families.
- Ramón Y Cajal T, Chirivella I, Miranda J, Teule A, Izquierdo Á, Balmaña J, Sánchez-Heras AB, Llort G, Fisas D, Lope V, Hernández-Agudo E, Juan-Fita MJ, Tena I, Robles L, Guillén-Ponce C, Pérez-Segura P, Luque-Molina MS, Hernando-Polo S, Salinas M, Brunet J, Salas-Trejo MD, Barnadas A, Pollán M.
- Breast Cancer Res. 2015 Jul 11;17:93. doi: 10.1186/s13058-015-0604-1.
- PMID: 26163143
- PubMed abstract
-
- Epidemiological and clinicopathological characteristics of BRCA-positive and BRCA-negative breast cancer patients in Greece.
- Triantafyllidou O, Vlachos IS, Apostolou P, Konstantopoulou I, Grivas A, Panopoulos C, Dimitrakakis C, Kassanos D, Loghis C, Bramis I, Vlahos N, Yannoukakos D, Fostira F.
- J BUON. 2015 Jul-Aug;20(4):978-84.
- PMID: 26416046
- PubMed abstract
- Table of Contents
-
- Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography.
- Møller P, Tharmaratnam K, Howell A, Stavrinos P, Sampson S, Wallace A, Maxwell AJ, Hagen AI, Evans DG.
- Breast Cancer Res Treat. 2015 Jul;152(1):87-94. doi: 10.1007/s10549-015-3448-6. Epub 2015 Jun 3.
- PMID: 26037256
- PubMed abstract
-
- Family history and outcome of young patients with breast cancer in the UK (POSH study).
- Eccles BK, Copson ER, Cutress RI, Maishman T, Altman DG, Simmonds P, Gerty SM, Durcan L, Stanton L, Eccles DM; POSH Study Steering Group.
- Br J Surg. 2015 Jul;102(8):924-35. doi: 10.1002/bjs.9816. Epub 2015 May 20.
- PMID: 25989914
- PubMed abstract
- Source abstract
-
- Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers.
- Wu S, Weinstein SP, DeLeo MJ 3rd, Conant EF, Chen J, Domchek SM, Kontos D.
- Breast Cancer Res. 2015 May 19;17(1):67. doi: 10.1186/s13058-015-0577-0.
- PMID: 25986460
- PubMed abstract
-
- Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population.
- van den Broek AJ, de Ruiter K, van 't Veer LJ, Tollenaar RA, van Leeuwen FE, Verhoef S, Schmidt MK.
- Eur J Hum Genet. 2015 May;23(5):588-595. doi: 10.1038/ejhg.2014.161. Epub 2014 Aug 20.
- PMID: 25138101
- PubMed abstract
- Source abstract
-
- Clinical and molecular characteristics of triple-negative breast cancer patients in Northern Israel: single center experience.
- Asleh-Aburaya K, Fried G.
- Springerplus. 2015 Mar 15;4:132. doi: 10.1186/s40064-015-0900-3. eCollection 2015.
- PMID: 25825688
- PubMed abstract
-
- Lobular breast cancer: incidence and genetic and non-genetic risk factors.
- Dossus L, Benusiglio PR.
- Breast Cancer Res. 2015 Mar 13;17:37. doi: 10.1186/s13058-015-0546-7.
- PMID: 25848941
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Familial Risks and Estrogen Receptor-Positive Breast Cancer in Hong Kong Chinese Women.
- Tse LA, Li M, Chan WC, Kwok CH, Leung SL, Wu C, Yu IT, Yu WC, Lao X, Wang X, Wong CK, Lee PM, Wang F, Yang XR.
- PLoS One. 2015 Mar 10;10(3):e0120741. doi: 10.1371/journal.pone.0120741.
- PMID: 25756203
- PubMed abstract
-
- Lobular breast cancer: molecular basis, mouse and cellular models.
- Christgen M, Derksen P.
- Breast Cancer Res. 2015 Feb 8;17:16. doi: 10.1186/s13058-015-0517-z.
- PMID: 25757734
- PubMed abstract
- Review
- Free PMC article
- Free Full Text
-
- Metastatic lobular breast carcinoma mimicking primary signet ring adenocarcinoma in a patient with a suspected CDH1 mutation.
- Mahmud N, Ford JM, Longacre TA, Parent R, Norton JA.
- J Clin Oncol. 2015 Feb 1;33(4):e19-21. doi: 10.1200/JCO.2013.49.1159. Epub 2014 Mar 3.
- PMID: 24590638
- PubMed abstract
- Case report
- Free Full Text
-
- Genotype/Phenotype correlations in patients with hereditary breast cancer.
- Wittersheim M, Büttner R, Markiefka B.
- Breast Care (Basel). 2015 Feb;10(1):22-6. doi: 10.1159/000380900.
- PMID: 25960721
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Tumor-associated inflammation as a potential prognostic tool in BRCA1/2-associated breast cancer.
- van Verschuer VM, Hooning MJ, van Baare-Georgieva RD, Hollestelle A, Timmermans AM, Koppert LB, Verhoog LC, Martens JW, Seynaeve C, van Deurzen CH.
- Hum Pathol. 2015 Feb;46(2):182-90. doi: 10.1016/j.humpath.2014.10.020. Epub 2014 Nov 15.
- PMID: 25522926
- PubMed abstract
- Source abstract
-
- Androgen receptor, EGFR, and BRCA1 as biomarkers in triple-negative breast cancer: a meta-analysis.
- Zhang L, Fang C, Xu X, Li A, Cai Q, Long X.
- Biomed Res Int. 2015;2015:357485. doi: 10.1155/2015/357485. Epub 2015 Jan 28.
- PMID: 25695063
- PubMed abstract
- Source abstract
- Meta-Analysis, Review
- Free PMC article
- Free Full Text
-
- Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers.
- Kuchenbaecker KB, Neuhausen SL, Robson M, Barrowdale D, McGuffog L, Mulligan AM, Andrulis IL, Spurdle AB, Schmidt MK, Schmutzler RK, Engel C, Wappenschmidt B, Nevanlinna H, Thomassen M, Southey M, Radice P, Ramus SJ, Domchek SM, Nathanson KL, Lee A, Healey S, Nussbaum RL, Rebbeck TR, Arun BK, James P, Karlan BY, Lester J, Cass I; Breast Cancer Family Registry, Terry MB, Daly MB, Goldgar DE, Buys SS, Janavicius R, Tihomirova L, Tung N, Dorfling CM, van Rensburg EJ, Steele L, v O Hansen T, Ejlertsen B, Gerdes AM, Nielsen FC, Dennis J, Cunningham J, Hart S, Slager S, Osorio A, Benitez J, Duran M, Weitzel JN, Tafur I, Hander M, Peterlongo P, Manoukian S, Peissel B, Roversi G, Scuvera G, Bonanni B, Mariani P, Volorio S, Dolcetti R, Varesco L, Papi L, Tibiletti MG, Giannini G, Fostira F, Konstantopoulou I, Garber J, Hamann U, Donaldson A, Brewer C, Foo C, Evans DG, Frost D, Eccles D; EMBRACE Study, Douglas F, Brady A, Cook J, Tischkowitz M, Adlard J, Barwell J, Ong KR, Walker L, Izatt L, Side LE, Kennedy MJ, Rogers MT, Porteous ME, Morrison PJ, Platte R, Eeles R, Davidson R, Hodgson S, Ellis S, Godwin AK, Rhiem K, Meindl A, Ditsch N, Arnold N, Plendl H, Niederacher D, Sutter C, Steinemann D, Bogdanova-Markov N, Kast K, Varon-Mateeva R, Wang-Gohrke S, Gehrig A, Markiefka B, Buecher B, Lefol C, Stoppa-Lyonnet D, Rouleau E, Prieur F, Damiola F; GEMO Study Collaborators, Barjhoux L, Faivre L, Longy M, Sevenet N, Sinilnikova OM, Mazoyer S, Bonadona V, Caux-Moncoutier V, Isaacs C, Van Maerken T, Claes K, Piedmonte M, Andrews L, Hays J, Rodriguez GC, Caldes T, de la Hoya M, Khan S, Hogervorst FB, Aalfs CM, de Lange JL, Meijers-Heijboer HE, van der Hout AH, Wijnen JT, van Roozendaal KE, Mensenkamp AR, van den Ouweland AM, van Deurzen CH, van der Luijt RB; HEBON, Olah E, Diez O, Lazaro C, Blanco I, Teulé A, Menendez M, Jakubowska A, Lubinski J, Cybulski C, Gronwald J, Jaworska-Bieniek K, Durda K, Arason A, Maugard C, Soucy P, Montagna M, Agata S, Teixeira MR; KConFab Investigators, Olswold C, Lindor N, Pankratz VS, Hallberg E, Wang X, Szabo CI, Vijai J, Jacobs L, Corines M, Lincoln A, Berger A, Fink-Retter A, Singer CF, Rappaport C, Kaulich DG, Pfeiler G, Tea MK, Phelan CM, Mai PL, Greene MH, Rennert G, Imyanitov EN, Glendon G, Toland AE, Bojesen A, Pedersen IS, Jensen UB, Caligo MA, Friedman E, Berger R, Laitman Y, Rantala J, Arver B, Loman N, Borg A, Ehrencrona H, Olopade OI, Simard J, Easton DF, Chenevix-Trench G, Offit K, Couch FJ, Antoniou AC; CIMBA.
- Breast Cancer Res. 2014 Dec 31;16(6):3416. doi: 10.1186/s13058-014-0492-9.
- PMID: 25919761
- PubMed abstract
-
- Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.
- Spurdle AB, Couch FJ, Parsons MT, McGuffog L, Barrowdale D, Bolla MK, Wang Q, Healey S, Schmutzler R, Wappenschmidt B, Rhiem K, Hahnen E, Engel C, Meindl A, Ditsch N, Arnold N, Plendl H, Niederacher D, Sutter C, Wang-Gohrke S, Steinemann D, Preisler-Adams S, Kast K, Varon-Mateeva R, Ellis S, Frost D, Platte R, Perkins J, Evans D, Izatt L, Eeles R, Adlard J, Davidson R, Cole T, Scuvera G, Manoukian S, Bonanni B, Mariette F, Fortuzzi S, Viel A, Pasini B, Papi L, Varesco L, Balleine R, Nathanson KL, Domchek SM, Offitt K, Jakubowska A, Lindor N, Thomassen M, Jensen U, Rantala J, Borg Å, Andrulis IL, Miron A, Hansen T, Caldes T, Neuhausen SL, Toland AE, Nevanlinna H, Montagna M, Garber J, Godwin AK, Osorio A, Factor RE, Terry MB, Rebbeck TR, Karlan BY, Southey M, Rashid M, Tung N, Pharoah P, Blows FM, Dunning AM, Provenzano E, Hall P, Czene K, Schmidt MK, Broeks A, Cornelissen S, Verhoef S, Fasching PA, Beckmann MW, Ekici AB, Slamon DJ, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Chang-Claude J, Flesch-Janys D, Rudolph A, Seibold P, Aittomäki K, Muranen TA, Heikkilä P, Blomqvist C, Figueroa J, Chanock SJ, Brinton L, Lissowska J, Olson JE, Pankratz VS, John EM, Whittemore AS, West DW, Hamann U, Torres D, Ulmer H, Rüdiger T, Devilee P, Tollenaar R, Seynaeve C, Van Asperen CJ, Eccles DM, Tapper WJ, Durcan L, Jones L, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N, Dwek M, Swann R, Bane AL, Glendon G, Mulligan AM, Giles GG, Milne RL, Baglietto L, McLean C, Carpenter J, Clarke C, Scott R, Brauch H, Brüning T, Ko YD, Cox A, Cross SS, Reed M, Lubinski J, Jaworska-Bieniek K, Durda K, Gronwald J, Dörk T, Bogdanova N, Park-Simon TW, Hillemanns P, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Burwinkel B, Marme F, Surovy H, Yang R, Anton-Culver H, Ziogas A, Hooning MJ, Collée J, Martens J, Tilanus-Linthorst M, Brenner H, Dieffenbach A, Arndt V, Stegmaier C, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Lindblom A, Margolin S, Joseph V, Robson M, Rau-Murthy R, González-Neira A, Arias J, Zamora P, Benítez J, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Peterlongo P, Zaffaroni D, Barile M, Capra F, Radice P, Teo SH, Easton DF, Antoniou AC, Chenevix-Trench G, Goldgar DE; ABCTB Investigators; EMBRACE Group; GENICA Network; HEBON Group; kConFab Investigators.
- Breast Cancer Res. 2014 Dec 23;16(6):3419. doi: 10.1186/s13058-014-0474-y.
- PMID: 25857409
- PubMed abstract
-
- Clinicopathological features of young patients (<35 years of age) with breast cancer in a Japanese Breast Cancer Society supported study.
- Kataoka A, Tokunaga E, Masuda N, Shien T, Kawabata K, Miyashita M.
- Breast Cancer. 2014 Nov;21(6):643-50. doi: 10.1007/s12282-013-0466-2. Epub 2013 Apr 16.
- PMID: 23588791
- PubMed abstract
- Source abstract
-
- Retraction: Relation between HPV genotypes and BRCA mutation in familial breast cancer.
- Rassi H, Mohammadian T, Salmanpor S, Gholami Roudmajani E.
- J Microbiol Biotechnol. 2014 Oct 8. doi: 10.4014/jmb.1407.07011. [Epub ahead of print]
- PMID: 25293631
- PubMed abstract
-
- Prognostic information of a previously diagnosed sister is an independent prognosticator for a newly diagnosed sister with breast cancer.
- Lindström LS, Li J, Lee M, Einbeigi Z, Hartman M, Hall P, Czene K.
- Ann Oncol. 2014 Oct;25(10):1966-72. doi: 10.1093/annonc/mdu270. Epub 2014 Jul 23.
- PMID: 25057175
- PubMed abstract
- Source abstract
-
- Comparison of nodal metastasis between BRCA mutation carriers and non-BRCA mutation carriers with breast cancer.
- Noori SF, Gangi A, Nelson ME, Choi M, Mirzadehgan P, Bonk AK, Mirocha J, Amersi F, Giuliano AE.
- Ann Surg Oncol. 2014 Oct;21(10):3324-9. doi: 10.1245/s10434-014-3904-2. Epub 2014 Jul 22.
- PMID: 25047471
- PubMed abstract
- Source abstract
-
- Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers.
- Gevensleben H, Bossung V, Meindl A, Wappenschmidt B, de Gregorio N, Osorio A, Romero A, Buettner R, Markiefka B, Schmutzler RK.
- Virchows Arch. 2014 Sep;465(3):365-9. doi: 10.1007/s00428-014-1619-1. Epub 2014 Jul 4.
- PMID: 24993905
- PubMed abstract
- Source abstract
-
- Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast.
- Valente AL, Rummel S, Shriver CD, Ellsworth RE.
- Hered Cancer Clin Pract. 2014 Jul 19;12(1):17. doi: 10.1186/1897-4287-12-17. eCollection 2014.
- PMID: 25067988
- PubMed abstract
-
- A multi-institutional study on the association between BRCA1/BRCA2 mutational status and triple-negative breast cancer in familial breast cancer patients.
- Seong MW, Kim KH, Chung IY, Kang E, Lee JW, Park SK, Lee MH, Lee JE, Noh DY, Son BH, Park HL, Cho SI, Park SS; Korean Hereditary Breast Cancer Study Group, Kim SW.
- Breast Cancer Res Treat. 2014 Jul;146(1):63-9. doi: 10.1007/s10549-014-3006-7. Epub 2014 Jun 4.
- PMID: 24894343
- PubMed abstract
- Source abstract
-
- Outcome of triple negative breast cancer: comparison of sporadic and BRCA1-associated cancers.
- Tung N, Gaughan E, Hacker MR, Lee LJ, Alexander B, Poles E, Schnitt SJ, Garber JE.
- Breast Cancer Res Treat. 2014 Jul;146(1):175-82. doi: 10.1007/s10549-014-2995-6. Epub 2014 May 18.
- PMID: 24839033
- PubMed abstract
- Source abstract
-
- A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.
- Anjum S, Fourkala EO, Zikan M, Wong A, Gentry-Maharaj A, Jones A, Hardy R, Cibula D, Kuh D, Jacobs IJ, Teschendorff AE, Menon U, Widschwendter M.
- Genome Med. 2014 Jun 27;6(6):47. doi: 10.1186/gm567. eCollection 2014.
- PMID: 25067956
- PubMed abstract
Press: Prospects for blood test to predict breast cancer risk. (PHG Foundation)
-
- Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.
- Jackson SA, Davis AA, Li J, Yi N, McCormick SR, Grant C, Fallen T, Crawford B, Loranger K, Litton J, Arun B, Vande Wydeven K, Sidani A, Farmer K, Sanders M, Hoskins K, Nussbaum R, Esserman L, Garber JE, Kaklamani VG; Northwestern Cancer Genetics Group.
- Cancer. 2014 May 15;120(10):1557-64. doi: 10.1002/cncr.28577. Epub 2014 Feb 12.
- PMID: 24522996
- PubMed abstract
- Source abstract
-
- Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.
- Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA, Skarlos D, Pectasides D, Fountzilas G, Beckmann MW, Hein A, Ruebner M, Ekici AB, Hartmann A, Schulz-Wendtland R, Renner SP, Janni W, Rack B, Scholz C, Neugebauer J, Andergassen U, Lux MP, Haeberle L, Clarke C, Pathmanathan N, Rudolph A, Flesch-Janys D, Nickels S, Olson JE, Ingle JN, Olswold C, Slettedahl S, Eckel-Passow JE, Anderson SK, Visscher DW, Cafourek VL, Sicotte H, Prodduturi N, Weiderpass E, Bernstein L, Ziogas A, Ivanovich J, Giles GG, Baglietto L, Southey M, Kosma VM, Fischer HP; GENICA Network, Reed MW, Cross SS, Deming-Halverson S, Shrubsole M, Cai Q, Shu XO, Daly M, Weaver J, Ross E, Klemp J, Sharma P, Torres D, Rüdiger T, Wölfing H, Ulmer HU, Försti A, Khoury T, Kumar S, Pilarski R, Shapiro CL, Greco D, Heikkilä P, Aittomäki K, Blomqvist C, Irwanto A, Liu J, Pankratz VS, Wang X, Severi G, Mannermaa A, Easton D, Hall P, Brauch H, Cox A, Zheng W, Godwin AK, Hamann U, Ambrosone C, Toland AE, Nevanlinna H, Vachon CM, Couch FJ.
- Carcinogenesis. 2014 May;35(5):1012-9. doi: 10.1093/carcin/bgt404. Epub 2013 Dec 9.
- PMID: 24325915
- PubMed abstract
- Source abstract
-
- Medullary breast carcinoma in an 18-year-old female: report on one case diagnosed on fine-needle cytology sample.
- Galzerano A, Rocco N, Accurso A, Ciancia G, Campanile AC, Caccavello F, Fulciniti F.
- Diagn Cytopathol. 2014 May;42(5):445-8. doi: 10.1002/dc.22947. Epub 2013 Jan 22.
- PMID: 23341107
- PubMed abstract
- Source abstract
-
- Genetic Susceptibility to Triple‐Negative Breast Cancers.
- Michelle W Wong‐Brown, Rodney J Scott.
- eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net ; 2014 May; doi: 10.1002/9780470015902.a0025352.
-
- Lobular breast cancer in a CDH1 splice site mutation carrier: case report and review of the literature.
- McVeigh TP, Choi JK, Miller NM, Green AJ, Kerin MJ.
- Clin Breast Cancer. 2014 Apr;14(2):e47-51. doi: 10.1016/j.clbc.2013.10.007. Epub 2013 Oct 25.
- PMID: 24333020
- PubMed abstract
- Source abstract
-
- Triple-negative breast cancer frequency and type of BRCA mutation: Clues from Sardinia.
- Palomba G, Budroni M, Olmeo N, Atzori F, Ionta MT, Pisano M, Tanda F, Cossu A, Palmieri G.
- Oncol Lett. 2014 Apr;7(4):948-952. Epub 2014 Jan 28.
- PMID: 24944648
- PubMed abstract
- Source abstract
-
- Male Breast Cancer and Hyperestrogenemia: A Thirteen-Year Review.
- Tariq KB, Al-Saffar F, Ibrahim S, Pham D, Farhangi A, Rana F, Zaiden R.
- World J Oncol. 2014 Apr;5(2):55-61. doi: 10.14740/wjon803w. Epub 2014 May 6.
- PMID: 29147378
- PubMed abstract
- Source abstract
-
- Association of BRCA1 germline mutations in young onset triple-negative breast cancer (TNBC).
- Andrés R, Pajares I, Balmaña J, Llort G, Ramón Y Cajal T, Chirivella I, Aguirre E, Robles L, Lastra E, Pérez-Segura P, Bosch N, Yagüe C, Lerma E, Godino J, Miramar MD, Moros M, Astier P, Saez B, Vidal MJ, Arcusa A, Ramón Y Cajal S, Calvo MT, Tres A.
- Clin Transl Oncol. 2014 Mar;16(3):280-4. doi: 10.1007/s12094-013-1070-9. Epub 2013 Aug 27.
- PMID: 23982851
- PubMed abstract
- Source abstract
-
- Germline CDH1 mutations in bilateral lobular carcinoma in situ.
- Petridis C, Shinomiya I, Kohut K, Gorman P, Caneppele M, Shah V, Troy M, Pinder SE, Hanby A, Tomlinson I, Trembath RC, Roylance R, Simpson MA, Sawyer EJ.
- Br J Cancer. 2014 Feb 18;110(4):1053-7. doi: 10.1038/bjc.2013.792. Epub 2013 Dec 24.
- PMID: 24366306
- PubMed abstract
- Source abstract
-
- Risk of having BRCA1 mutation in high-risk women with triple-negative breast cancer: a meta-analysis.
- Tun N, Villani G, Ong K, Yoe L, Bo Z.
- Clin Genet. 2014 Jan;85(1):43-8. doi: 10.1111/cge.12270. Epub 2013 Oct 3.
- PMID: 24000781
- PubMed abstract
- Source abstract
-
- Lobulitis in nonneoplastic breast tissue from breast cancer patients: association with phenotypes that are common in hereditary breast cancer.
- Gulbahce HE, Vanderwerf S, Blair C, Sweeney C.
- Hum Pathol. 2014 Jan;45(1):78-84. doi: 10.1016/j.humpath.2013.08.008. Epub 2013 Oct 21.
- PMID: 24157064
- PubMed abstract
- Source abstract
-
- Prognostic role of BRCA1 mutation in patients with triple-negative breast cancer.
- Maksimenko J, Irmejs A, Nakazawa-Miklasevica M, Melbarde-Gorkusa I, Trofimovics G, Gardovskis J, Miklasevics E.
- Oncol Lett. 2014 Jan;7(1):278-284. Epub 2013 Nov 14.
- PMID: 24348864
- PubMed abstract
- Source abstract
-
- A germline mosaic BRCA1 exon deletion in a woman with bilateral basal-like breast cancer.
- Delon I, Taylor A, Molenda A, Drummond J, Oakhill K, Girling A, Liu H, Whittaker J, Treacy R, Tischkowitz M.
- Clin Genet. 2013 Sep;84(3):297-9. doi: 10.1111/cge.12057. Epub 2012 Dec 6.
- PMID: 23216102
- PubMed abstract
- Source abstract
-
- Frequency of 5382insC mutation of BRCA1 gene among breast cancer patients: an experience from Eastern India.
- Chakraborty A, Mukhopadhyay A, Bhattacharyya D, Bose CK, Choudhuri K, Mukhopadhyay S, Basak J.
- Fam Cancer. 2013 Sep;12(3):489-95. doi: 10.1007/s10689-012-9590-y.
- PMID: 23232912
- PubMed abstract
- Source abstract
-
- [Characteristics of selected clinical features in BRCA1 mutation carriers affected with breast cancer undergoing preventive female genital tract surgeries].
- Menkiszak J, Chudecka-Głaz A, Gronwald J, Bedner R, Cymbaluk-Płoska A, Wezowska M, Zielińska D, Rzepka-Górska I.
- Ginekol Pol. 2013 Sep;84(9):758-64.
- PMID: 24191513
- PubMed abstract
- Source abstract
- [Article in Polish]
- Free Full Text
-
- Association between BRCA Mutation Status, Pathological Findings, and Magnetic Resonance Imaging Features in Patients with Breast Cancer at Risk for the Mutation.
- Noh JM, Han BK, Choi DH, Rhee SJ, Cho EY, Huh SJ, Park W, Park H, Nam SJ, Lee JE, Kil WH.
- J Breast Cancer. 2013 Sep;16(3):308-14. doi: 10.4048/jbc.2013.16.3.308. Epub 2013 Sep 30.
- PMID: 24155760
- PubMed abstract
- Source abstract
-
- Are bilateral breast cancers different from breast cancers coexisting with ovarian cancer? An immunohistochemical analysis aimed at intrinsic tumor phenotype.
- Senkus E, Szade J, Pieczyńska B, Żaczek A, Brożek I, Radecka B, Kowalczyk A, Wełnicka-Jaśkiewicz M, Jassem J.
- Breast. 2013 Aug;22(4):425-30. doi: 10.1016/j.breast.2013.04.005. Epub 2013 May 1.
- PMID: 23642527
- PubMed abstract
- Source abstract
-
- Angiogenetic axis angiopoietins/Tie2 and VEGF in familial breast cancer.
- Danza K, Pilato B, Lacalamita R, Addati T, Giotta F, Bruno A, Paradiso A, Tommasi S.
- Eur J Hum Genet. 2013 Aug;21(8):824-30. doi: 10.1038/ejhg.2012.273. Epub 2012 Dec 12.
- PMID: 23232696
- PubMed abstract
- Source abstract
-
- The complex genetic landscape of familial breast cancer.
- Melchor L, Benítez J.
- Hum Genet. 2013 Aug;132(8):845-63. doi: 10.1007/s00439-013-1299-y. Epub 2013 Apr 5.
- PMID: 23552954
- PubMed abstract
- Source abstract
-
- Tuberin and p27 expression in breast cancer patients with or without BRCA germline mutations.
- Dressler AC, Hudelist G, Fink-Retter A, Gschwantler-Kaulich D, Pfeiler G, Rosner M, Hengstschläger M, Singer CF.
- J Cancer Res Clin Oncol. 2013 Aug;139(8):1349-55. doi: 10.1007/s00432-013-1443-z. Epub 2013 May 21.
- PMID: 23689538
- PubMed abstract
- Source abstract
-
- Tumour morphology predicts PALB2 germline mutation status.
- Teo ZL, Provenzano E, Dite GS, Park DJ, Apicella C, Sawyer SD, James PA, Mitchell G, Trainer AH, Lindeman GJ, Shackleton K, Cicciarelli L; kConFab, Buys SS, Andrulis IL, Mulligan AM, Glendon G, John EM, Terry MB, Daly M, Odefrey FA, Nguyen-Dumont T, Giles GG, Dowty JG, Winship I, Goldgar DE, Hopper JL, Southey MC.
- Br J Cancer. 2013 Jul 9;109(1):154-63. doi: 10.1038/bjc.2013.295. Epub 2013 Jun 20.
- PMID: 23787919
- PubMed abstract
- Source abstract
-
- Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations.
- George J, Alsop K, Etemadmoghadam D, Hondow H, Mikeska T, Dobrovic A, deFazio A; Australian Ovarian Cancer Study Group, Smyth GK, Levine DA, Mitchell G, Bowtell DD.
- Clin Cancer Res. 2013 Jul 1;19(13):3474-84. doi: 10.1158/1078-0432.CCR-13-0066. Epub 2013 Apr 30.
- PMID: 23633455
- PubMed abstract
- Source abstract
Research news:
Genomic signatures of BRCA1 but not BRCA2 associated high-grade serous carcinoma resemble basal-like breast cancer.
- PMID: 24127632
- PubMed abstract
- Source abstract
-
- Clinical-pathologic significance of cancer stem cell marker expression in familial breast cancers.
- Bane A, Viloria-Petit A, Pinnaduwage D, Mulligan AM, O'Malley FP, Andrulis IL.
- Breast Cancer Res Treat. 2013 Jul;140(1):195-205. doi: 10.1007/s10549-013-2591-1. Epub 2013 Jun 28.
- PMID: 23813303
- PubMed abstract
-
- Breast Cancer Gene Mutations More Common in Black Women.
- Johnson K.
- Medscape Medical News. Conference News. 2013 Jun 6.
- Conference report
- Free Full Text
-
- Breast cancer in women aged 25 years and younger.
- Dimitrakakis C, Tsigginou A, Zagouri F, Marinopoulos S, Sergentanis TN, Keramopoulos A, Liakou P, Zografos GC, Papadimitriou CA, Dimopoulos MA, Antsaklis A.
- Obstet Gynecol. 2013 Jun;121(6):1235-40. doi: 10.1097/AOG.0b013e318291ef9a.
- PMID: 23812457
- PubMed abstract
-
- BRCA1 mutations and luminal-basal transformation.
- Ng T, Irshad S, Stebbing J.
- Oncogene. 2013 May 30;32(22):2712-4. doi: 10.1038/onc.2012.379. Epub 2012 Aug 27.
- PMID: 22926516
- PubMed abstract
- Source abstract
Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation.
- PMID: 22777348
- PubMed abstract
- Source abstract
-
- Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation.
- Bai F, Smith MD, Chan HL, Pei XH.
- Oncogene. 2013 May 30;32(22):2715-25. doi: 10.1038/onc.2012.293. Epub 2012 Jul 9.
- PMID: 22777348
- PubMed abstract
- Source abstract
Comment:
BRCA1 mutations and luminal-basal transformation.
- PMID: 22926516
- PubMed abstract
- Source abstract
-
- Prevalence of germline TP53 mutations in HER2+ breast cancer patients.
- Rath MG, Masciari S, Gelman R, Miron A, Miron P, Foley K, Richardson AL, Krop IE, Verselis SJ, Dillon DA, Garber JE.
- Breast Cancer Res Treat. 2013 May;139(1):193-8. doi: 10.1007/s10549-012-2375-z. Epub 2013 Apr 12.
- PMID: 23580068
- PubMed abstract
- Source abstract
-
- Genetic susceptibility to triple-negative breast cancer.
- Stevens KN, Vachon CM, Couch FJ.
- Cancer Res. 2013 Apr 1;73(7):2025-30. doi: 10.1158/0008-5472.CAN-12-1699. Epub 2013 Mar 27.
- PMID: 23536562
- PubMed abstract
- Source abstract
- Review
- Free PMC article
- Free Full Text
-
- Lipid metabolism genes in contralateral unaffected breast and estrogen receptor status of breast cancer.
- Wang J, Scholtens D, Holko M, Ivancic D, Lee O, Hu H, Chatterton RT Jr, Sullivan ME, Hansen N, Bethke K, Zalles CM, Khan SA.
- Cancer Prev Res (Phila). 2013 Apr;6(4):321-30. doi: 10.1158/1940-6207.CAPR-12-0304. Epub 2013 Mar 19.
- PMID: 23512947
- PubMed abstract
- Source abstract
Press: Breast cancer gene test could allow preventive treatment. (The Telegraph)
-
- Prevalence of BRCA1 and BRCA2 Germline Mutations in Breast Cancer Women of Multiple Ethnic Region in Northwest China.
- Ou J, Wu T, Sijmons R, Ni D, Xu W, Upur H.
- J Breast Cancer. 2013 Mar;16(1):50-4. doi: 10.4048/jbc.2013.16.1.50. Epub 2013 Mar 31.
- PMID: 23593081
- PubMed abstract
- Source abstract
-
- [Expression of BRCA1 and WWOX and their clinicopathologic implication in breast carcinomas occurring in young women].
- Zhang QL, Zhang QH, Cong H, Zhang XL.
- Zhonghua Bing Li Xue Za Zhi. 2013 Feb;42(2):90-4. doi: 10.3760/cma.j.issn.0529-5807.2013.02.005.
- PMID: 23710914
- PubMed abstract
- Source abstract
-
- Methylation of BRCA1 promoter region is associated with unfavorable prognosis in women with early-stage breast cancer.
- Hsu NC, Huang YF, Yokoyama KK, Chu PY, Chen FM, Hou MF.
- PLoS One. 2013;8(2):e56256. doi: 10.1371/journal.pone.0056256. Epub 2013 Feb 6.
- PMID: 23405268
- PubMed abstract
-
- First description of an acinic cell carcinoma of the breast in a BRCA1 mutation carrier: a case report.
- Ripamonti CB, Colombo M, Mondini P, Siranoush M, Peissel B, Bernard L, Radice P, Carcangiu ML.
- BMC Cancer. 2013 Feb 1;13:46. doi: 10.1186/1471-2407-13-46.
- PMID: 23374397
- PubMed abstract
- Case report
- Free PMC article
- Free Full Text
-
- VEGF, HIF-1α expression and MVD as an angiogenic network in familial breast cancer.
- http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053070Saponaro C, Malfettone A, Ranieri G, Danza K, Simone G, Paradiso A, Mangia A.
- PLoS One. 2013;8(1):e53070. doi: 10.1371/journal.pone.0053070. Epub 2013 Jan 11.
- PMID: 23326384
- PubMed abstract
-
- Paget disease of the breast with invasion from nipple skin into the dermis: an unusual type of skin invasion not associated with an adverse outcome.
- Sanders MA, Dominici L, Denison C, Golshan M, Wiecorek T, Lester SC.
- Arch Pathol Lab Med. 2013 Jan;137(1):72-6. doi: 10.5858/arpa.2011-0611-OA.
- PMID: 23276177
- PubMed abstract
- Source abstract
-
- Evaluation of BRCA1 mutations in an unselected patient population with triple-negative breast cancer.
- Rummel S, Varner E, Shriver CD, Ellsworth RE.
- Breast Cancer Res Treat. 2013 Jan;137(1):119-25. doi: 10.1007/s10549-012-2348-2. Epub 2012 Nov 29.
- PMID: 23192404
- PubMed abstract
- Source abstract
-
- The penetrance of ductal carcinoma in situ among BRCA1 and BRCA2 mutation carriers.
- Mazzola E, Cheng SC, Parmigiani G.
- Breast Cancer Res Treat. 2013 Jan;137(1):315-8. doi: 10.1007/s10549-012-2345-5. Epub 2012 Nov 27.
- PMID: 23184082
- PubMed abstract
- Source abstract
-
- Genotype in BRCA-associated Breast Cancers.
- Meric-Bernstam F, Gutierrez-Barrera AM, Litton J, Mellor-Crummey L, Ready K, Gonzalez-Angulo AM, Lu KH, Hortobagyi GN, Arun BK.
- Breast J. 2013 Jan;19(1):87-91. doi: 10.1111/tbj.12056. Epub 2012 Dec 10.
- PMID: 23231005
- PubMed abstract
- Source abstract
-
- Genetic susceptibility Loci for subtypes of breast cancer in an african american population.
- Palmer JR, Ruiz-Narvaez EA, Rotimi CN, Cupples LA, Cozier YC, Adams-Campbell LL, Rosenberg L.
- Cancer Epidemiol Biomarkers Prev. 2013 Jan;22(1):127-34. doi: 10.1158/1055-9965.EPI-12-0769. Epub 2012 Nov 7.
- PMID: 23136140
- PubMed abstract
- Source abstract
-
- HOX gene methylation status analysis in patients with hereditary breast cancer.
- Pilato B, Pinto R, De Summa S, Lambo R, Paradiso A, Tommasi S.
- J Hum Genet. 2013 Jan;58(1):51-3. doi: 10.1038/jhg.2012.118. Epub 2012 Oct 11.
- PMID: 23051705
- PubMed abstract
- Source abstract
-
- Frequency of Triple-Negative Breast Cancer in BRCA1 Mutation Carriers: Comparison Between Common Ashkenazi Jewish and Other Mutations.
- Tung N, Garber JE, Lincoln A, Domchek SM.
- J Clin Oncol. 2012 Dec 10;30(35):4447-8. doi: 10.1200/JCO.2012.44.5635. Epub 2012 Oct 22.
- PMID: 23091104
- PubMed abstract
- Comment, Letter
- Free Full Text
Characteristics of triple-negative breast cancer in patients with a BRCA1 mutation: results from a population-based study of young women.
- PMID: 22010008
- PubMed abstract
- Free Full Text
-
- Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer.
- Phuah SY, Looi LM, Hassan N, Rhodes A, Dean S, Taib NA, Yip CH, Teo SH.
- Breast Cancer Res. 2012 Nov 2;14(6):R142. doi: 10.1186/bcr3347.
- PMID: 23116406
- PubMed abstract
-
- Tissue-based predictors of germ-line BRCA1 mutations: implications for triaging of genetic testing.
- de la Cruz J, Andre F, Harrell RK, Bassett RL Jr, Arun B, Mathieu MC, Delaloge S, Gilcrease MZ.
- Hum Pathol. 2012 Nov;43(11):1932-9. doi: 10.1016/j.humpath.2012.02.002. Epub 2012 May 14.
- PMID: 22591913
- PubMed abstract
- Source abstract
-
- Pathologic features and immunophenotype of estrogen receptor-positive breast cancers in BRCA1 mutation carriers.
- Kaplan JS, Schnitt SJ, Collins LC, Wang Y, Garber JE, Montgomery K, West RB, Krag K, Fetten K, Lincoln A, Tung NM.
- Am J Surg Pathol. 2012 Oct;36(10):1483-8. doi: 10.1097/PAS.0b013e31825789ed.
- PMID: 22613997
- PubMed abstract
- Source abstract
-
- Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry.
- Dite GS, Makalic E, Schmidt DF, Giles GG, Hopper JL, Southey MC.
- Breast Cancer Res. 2012 Aug 28;14(4):R122. doi: 10.1186/bcr3248.
- PMID: 22929433
- PubMed abstract
-
- The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.
- Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Gruvberger-Saal SK, Saal LH, Holm K, Hegardt C, Arason A, Fagerholm R, Persson C, Grabau D, Johnsson E, Lövgren K, Magnusson L, Heikkilä P, Agnarsson BA, Johannsson OT, Malmström P, Fernö M, Olsson H, Loman N, Nevanlinna H, Barkardottir RB, Borg Å.
- Cancer Res. 2012 Aug 15;72(16):4028-36. Epub 2012 Jun 15.
- PMID: 22706203
- PubMed abstract
- Source abstract
-
- Comparison of the effects of genetic and environmental risk factors on in situ and invasive ductal breast cancer.
- Reeves GK, Pirie K, Green J, Bull D, Beral V; For the Million Women Study Collaborators.
- Int J Cancer. 2012 Aug 15;131(4):930-937. doi: 10.1002/ijc.26460. Epub 2011 Nov 28.
- PMID: 21952983
- PubMed abstract
- Source abstract
-
- Molecular insights on basal-like breast cancer.
- Valentin MD, da Silva SD, Privat M, Alaoui-Jamali M, Bignon YJ.
- Breast Cancer Res Treat. 2012 Jul;134(1):21-30. doi: 10.1007/s10549-011-1934-z. Epub 2012 Jan 11.
- PMID: 22234518
- PubMed abstract
- Source abstract
-
- Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: implications for genetic screening selection criteria: a Hellenic Cooperative Oncology Group Study.
- Fostira F, Tsitlaidou M, Papadimitriou C, Pertesi M, Timotheadou E, Stavropoulou AV, Glentis S, Bournakis E, Bobos M, Pectasides D, Papakostas P, Pentheroudakis G, Gogas H, Skarlos P, Samantas E, Bafaloukos D, Kosmidis PA, Koutras A, Yannoukakos D, Konstantopoulou I, Fountzilas G.
- Breast Cancer Res Treat. 2012 Jul;134(1):353-62. doi: 10.1007/s10549-012-2021-9. Epub 2012 Mar 21.
- PMID: 22434525
- PubMed abstract
- Source abstract
-
- Prevalence of BRCA mutations in an unselected population of triple-negative breast cancer.
- Hartman AR, Kaldate RR, Sailer LM, Painter L, Grier CE, Endsley RR, Griffin M, Hamilton SA, Frye CA, Silberman MA, Wenstrup RJ, Sandbach JF.
- Cancer. 2012 Jun 1;118(11):2787-95. doi: 10.1002/cncr.26576. Epub 2011 Oct 5.
- PMID: 22614657
- PubMed abstract
- Source abstract
-
- BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype.
- Santarosa M, Maestro R.
- Cancer Metastasis Rev. 2012 Jun;31(1-2):131-42. doi: 10.1007/s10555-011-9336-6.
- PMID: 22101651
- PubMed abstract
- Source abstract
-
- BRCA2 mutations and triple-negative breast cancer.
- Meyer P, Landgraf K, Högel B, Eiermann W, Ataseven B.
- PLoS One. 2012;7(5):e38361. doi: 10.1371/journal.pone.0038361. Epub 2012 May 30.
- PMID: 22666503
- PubMed abstract
-
- BRCA1 and BRCA2: a common pathway of genome protection but different breast cancer subtypes.
- Joosse SA.
- Nat Rev Cancer. 2012 May 24;12(5):372. doi: 10.1038/nrc3181-c2.
- PMID: 22525577
- PubMed abstract
- Source abstract
-
- Different CHEK2 germline mutations are associated with distinct immunophenotypic molecular subtypes of breast cancer.
- Domagala P, Wokolorczyk D, Cybulski C, Huzarski T, Lubinski J, Domagala W.
- Breast Cancer Res Treat. 2012 Apr;132(3):937-45. Epub 2011 Jun 24.
- PMID: 21701879
- PubMed abstract
- Source abstract
-
- Prevalence and characterization of BRCA1 and BRCA2 germline mutations in Chinese women with familial breast cancer.
- Zhang J, Pei R, Pang Z, Ouyang T, Li J, Wang T, Fan Z, Fan T, Lin B, Xie Y.
- Breast Cancer Res Treat. 2012 Apr;132(2):421-8. doi: 10.1007/s10549-011-1596-x. Epub 2011 May 26.
- PMID: 21614564
- PubMed abstract
- Source abstract
-
- Gene expression profiling assigns CHEK2 1100delC breast cancers to the luminal intrinsic subtypes.
- Nagel JH, Peeters JK, Smid M, Sieuwerts AM, Wasielewski M, de Weerd V, Trapman-Jansen AM, van den Ouweland A, Brüggenwirth H, van Ijcken WF, Klijn JG, van der Spek PJ, Foekens JA, Martens JW, Schutte M, Meijers-Heijboer H.
- Breast Cancer Res Treat. 2012 Apr;132(2):439-48. doi: 10.1007/s10549-011-1588-x. Epub 2011 May 26.
- PMID: 21614566
- PubMed abstract
- Source abstract
-
- Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
- Couch FJ, Gaudet MM, Antoniou AC, Ramus SJ, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, Wang X, Kirchhoff T, McGuffog L, Barrowdale D, Lee A, Healey S, Sinilnikova OM, Andrulis IL; OCGN, Ozcelik H, Mulligan AM, Thomassen M, Gerdes AM, Jensen UB, Skytte AB, Kruse TA, Caligo MA, von Wachenfeldt A, Barbany-Bustinza G, Loman N, Soller M, Ehrencrona H, Karlsson P; SWE-BRCA, Nathanson KL, Rebbeck TR, Domchek SM, Jakubowska A, Lubinski J, Jaworska K, Durda K, Zlowocka E, Huzarski T, Byrski T, Gronwald J, Cybulski C, Górski B, Osorio A, Durán M, Tejada MI, Benitez J, Hamann U, Hogervorst FB; HEBON, van Os TA, van Leeuwen FE, Meijers-Heijboer HE, Wijnen J, Blok MJ, Kets M, Hooning MJ, Oldenburg RA, Ausems MG, Peock S, Frost D, Ellis SD, Platte R, Fineberg E, Evans DG, Jacobs C, Eeles RA, Adlard J, Davidson R, Eccles DM, Cole T, Cook J, Paterson J, Brewer C, Douglas F, Hodgson SV, Morrison PJ, Walker L, Porteous ME, Kennedy MJ, Side LE; EMBRACE, Bove B, Godwin AK, Stoppa-Lyonnet D; GEMO Study Collaborators, Fassy-Colcombet M, Castera L, Cornelis F, Mazoyer S, Léoné M, Boutry-Kryza N, Bressac-de Paillerets B, Caron O, Pujol P, Coupier I, Delnatte C, Akloul L, Lynch HT, Snyder CL, Buys SS, Daly MB, Terry M, Chung WK, John EM, Miron A, Southey MC, Hopper JL, Goldgar DE, Singer CF, Rappaport C, Tea MK, Fink-Retter A, Hansen TV, Nielsen FC, Arason A, Vijai J, Shah S, Sarrel K, Robson ME, Piedmonte M, Phillips K, Basil J, Rubinstein WS, Boggess J, Wakeley K, Ewart-Toland A, Montagna M, Agata S, Imyanitov EN, Isaacs C, Janavicius R, Lazaro C, Blanco I, Feliubadalo L, Brunet J, Gayther SA, Pharoah PP, Odunsi KO, Karlan BY, Walsh CS, Olah E, Teo SH, Ganz PA, Beattie MS, van Rensburg EJ, Dorfling CM, Diez O, Kwong A, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ditsch N, Arnold N, Heidemann S, Niederacher D, Preisler-Adams S, Gadzicki D, Varon-Mateeva R, Deissler H, Gehrig A, Sutter C, Kast K, Fiebig B, Heinritz W, Caldes T, de la Hoya M, Muranen TA, Nevanlinna H, Tischkowitz MD, Spurdle AB, Neuhausen SL, Ding YC, Lindor NM, Fredericksen Z, Pankratz VS, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Barile M, Bernard L, Viel A, Giannini G, Varesco L, Radice P, Greene MH, Mai PL, Easton DF, Chenevix-Trench G; kConFab investigators, Offit K, Simard J; Consortium of Investigators of Modifiers of BRCA1/2.
- Cancer Epidemiol Biomarkers Prev. 2012 Apr;21(4):645-57. doi: 10.1158/1055-9965.EPI-11-0888. Epub 2012 Feb 20.
- PMID: 2235161
- PubMed abstract
- Source abstract
-
- Occurrence of breast cancer subtypes in adolescent and young adult women.
- Keegan TH, Derouen MC, Press DJ, Kurian AW, Clarke CA.
- Breast Cancer Res. 2012 Mar 27;14(2):R55.
- PMID: 22452927
- PubMed abstract
-
- Predictive factors for BRCA1/BRCA2 mutations in women with ductal carcinoma in situ.
- Bayraktar S, Elsayegh N, Gutierrez Barrera AM, Lin H, Kuerer H, Tasbas T, Muse KI, Ready K, Litton J, Meric-Bernstam F, Hortobagyi GN, Albarracin CT, Arun B.
- Cancer. 2012 Mar 15;118(6):1515-22. doi: 10.1002/cncr.26428. Epub 2011 Aug 25.
- PMID: 22009639
- PubMed abstract
- Source abstract
Comments from NSGC Discussion Forum Cancer SIG
Subject: Does anyone have a good reference for the occurence of DCIS in hereditary cancer syndromes?
-
- Clinical implications for BRCA gene mutation in breast cancer.
- Xu J, Wang B, Zhang Y, Li R, Wang Y, Zhang S.
- Mol Biol Rep. 2012 Mar;39(3):3097-102. doi: 10.1007/s11033-011-1073-y. Epub 2011 Jun 21.
- PMID: 21691706
- PubMed abstract
- Source abstract
-
- Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.
- Antoniou AC, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, McGuffog L, Lee A, Barrowdale D, Healey S, Sinilnikova OM, Caligo MA, Loman N, Harbst K, Lindblom A, Arver B, Rosenquist R, Karlsson P, Nathanson K, Domchek S, Rebbeck T, Jakubowska A, Lubinski J, Jaworska K, Durda K, Złowowcka-Perłowska E, Osorio A, Durán M, Andrés R, Benítez J, Hamann U, Hogervorst FB, van Os TA, Verhoef S, Meijers-Heijboer HE, Wijnen J, Gómez Garcia EB, Ligtenberg MJ, Kriege M, Collée JM, Ausems MG, Oosterwijk JC, Peock S, Frost D, Ellis SD, Platte R, Fineberg E, Evans DG, Lalloo F, Jacobs C, Eeles R, Adlard J, Davidson R, Cole T, Cook J, Paterson J, Douglas F, Brewer C, Hodgson S, Morrison PJ, Walker L, Rogers MT, Donaldson A, Dorkins H, Godwin AK, Bove B, Stoppa-Lyonnet D, Houdayer C, Buecher B, de Pauw A, Mazoyer S, Calender A, Léoné M, Bressac-de Paillerets B, Caron O, Sobol H, Frenay M, Prieur F, Ferrer SU, Mortemousque I, Buys S, Daly M, Miron A, Terry MU, Hopper JL, John EM, Southey M, Goldgar D, Singer CF, Fink-Retter A, Tea MK, Kaulich DU, Hansen TV, Nielsen FC, Barkardottir RB, Gaudet M, Kirchhoff T, Joseph V, Dutra-Clarke A, Offit K, Piedmonte M, Kirk J, Cohn D, Hurteau J, Byron J, Fiorica J, Toland AE, Montagna M, Oliani C, Imyanitov E, Isaacs C, Tihomirova L, Blanco I, Lazaro C, Teulé A, Valle JD, Gayther SA, Odunsi K, Gross J, Karlan BY, Olah E, Teo SH, Ganz PA, Beattie MS, Dorfling CM, van Rensburg EU, Diez O, Kwong A, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ditsch N, Arnold N, Heidemann S, Niederacher D, Preisler-Adams S, Gadzicki D, Varon-Mateeva R, Deissler H, Gehrig A, Sutter C, Kast K, Fiebig B, Schäfer D, Caldes T, de la Hoya M, Nevanlinna H, Muranen TA, Lespérance B, Spurdle AB, Neuhausen SL, Ding YC, Wang X, Fredericksen Z, Pankratz VS, Lindor NM, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Bonanni B, Bernard L, Dolcetti R, Papi L, Ottini L, Radice P, Greene MH, Loud JT, Andrulis IL, Ozcelik H, Mulligan AU, Glendon G, Thomassen M, Gerdes AM, Jensen UB, Skytte AB, Kruse TA, Chenevix-Trench G, Couch FJ, Simard J, Easton DF; CIMBA, SWE-BRCA; HEBON; EMBRACE; GEMO Collaborators Study; kConFab Investigators.
- Breast Cancer Res. 2012 Feb 20;14(1):R33.
- PMID: 22348646
- PubMed abstract
-
- Pathologic features and molecular phenotype by patient age in a large cohort of young women with breast cancer.
- Collins LC, Marotti JD, Gelber S, Cole K, Ruddy K, Kereakoglow S, Brachtel EF, Schapira L, Come SE, Winer EP, Partridge AH.
- Breast Cancer Res Treat. 2012 Feb;131(3):1061-6. doi: 10.1007/s10549-011-1872-9. Epub 2011 Nov 13.
- PMID: 22080245
- PubMed abstract
- Source abstract
-
- Tetraploidy in BRCA2 breast tumours.
- Jonsdottir AB, Stefansson OA, Bjornsson J, Jonasson JG, Ogmundsdottir HM, Eyfjord JE.
- Eur J Cancer. 2012 Feb;48(3):305-10. doi: 10.1016/j.ejca.2011.11.008. Epub 2011 Nov 29.
- PMID: 22133571
- PubMed abstract
- Source abstract
-
- Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).
- Mavaddat N, Barrowdale D, Andrulis IL, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Spurdle A, Robson M, Sherman M, Mulligan AM, Couch FJ, Engel C, McGuffog L, Healey S, Sinilnikova OM, Southey MC, Terry MB, Goldgar D, O'Malley F, John EM, Janavicius R, Tihomirova L, Hansen TV, Nielsen FC, Osorio A, Stavropoulou A, Benítez J, Manoukian S, Peissel B, Barile M, Volorio S, Pasini B, Dolcetti R, Putignano AL, Ottini L, Radice P, Hamann U, Rashid MU, Hogervorst FB, Kriege M, van der Luijt RB; HEBON, Peock S, Frost D, Evans DG, Brewer C, Walker L, Rogers MT, Side LE, Houghton C; EMBRACE, Weaver J, Godwin AK, Schmutzler RK, Wappenschmidt B, Meindl A, Kast K, Arnold N, Niederacher D, Sutter C, Deissler H, Gadzicki D, Preisler-Adams S, Varon-Mateeva R, Schönbuchner I, Gevensleben H, Stoppa-Lyonnet D, Belotti M, Barjhoux L; GEMO Study Collaborators, Isaacs C, Peshkin BN, Caldes T, de la Hoya M, Cañadas C, Heikkinen T, Heikkilä P, Aittomäki K, Blanco I, Lazaro C, Brunet J, Agnarsson BA, Arason A, Barkardottir RB, Dumont M, Simard J, Montagna M, Agata S, D'Andrea E, Yan M, Fox S; kConFab Investigators, Rebbeck TR, Rubinstein W, Tung N, Garber JE, Wang X, Fredericksen Z, Pankratz VS, Lindor NM, Szabo C, Offit K, Sakr R, Gaudet MM, Singer CF, Tea MK, Rappaport C, Mai PL, Greene MH, Sokolenko A, Imyanitov E, Toland AE, Senter L, Sweet K, Thomassen M, Gerdes AM, Kruse T, Caligo M, Aretini P, Rantala J, von Wachenfeld A, Henriksson K; SWE-BRCA Collaborators, Steele L, Neuhausen SL, Nussbaum R, Beattie M, Odunsi K, Sucheston L, Gayther SA, Nathanson K, Gross J, Walsh C, Karlan B, Chenevix-Trench G, Easton DF, Antoniou AC; Consortium of Investigators of Modifiers of BRCA1/2.
- Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):134-47. doi: 10.1158/1055-9965.EPI-11-0775. Epub 2011 Dec 5.
- PMID: 22144499
- PubMed abstract
- Source abstract
Comments from NSGC Discussion Forum Cancer SIG
Subject: Article Request
-
- Basal breast cancer: a complex and deadly molecular subtype.
- Bertucci F, Finetti P, Birnbaum D.
- Curr Mol Med. 2012 Jan;12(1):96-110.
- PMID: 22082486
- PubMed abstract
- Source abstract
- Review
- Free PMC article
-
- The CHEK2 I157T variant and breast cancer susceptibility: a systematic review and meta-analysis.
- Liu C, Wang Y, Wang QS, Wang YJ.
- Asian Pac J Cancer Prev. 2012;13(4):1355-60.
- PMID: 22799331
- PubMed abstract
- Source abstract
- Meta-Analysis, Review
- Free Full Text (PDF)
-
- CHEK2 gene alterations independently increase the risk of death from breast cancer in Bulgarian patients.
- Angelova SG, Krasteva ME, Gospodinova ZI, Georgieva EI.
- Neoplasma. 2012;59(6):622-30. doi: 10.4149/neo_2012_079.
- PMID: 22862163
- PubMed abstract
- Source abstract