LitAlert ~~ GeneLit.com

    • An Overview on Radiation Sensitivity in Hereditary Breast and Ovarian Cancer Syndrome.
    • Gonçalves D, Pires AS, Marques IA, Gomes I, Sousa G, Botelho MF, Abrantes AM.
    • Cancers (Basel). 2022 Jul 2;14(13):3254. doi: 10.3390/cancers14133254.
    • Surgical Management of Inherited Breast Cancer: Role of Breast-Conserving Surgery.
    • Magnoni F, Sacchini V, Veronesi P, Bianchi B, Bottazzoli E, Tagliaferri V, Mazzotta E, Castelnovo G, Deguidi G, Rossi EMC, Corso G.
    • Cancers (Basel). 2022 Jul 1;14(13):3245. doi: 10.3390/cancers14133245.
    • Rucaparib for recurrent ovarian cancer with BRCA1 and BRCA2 mutations.
    • Ganguly S, Gogia A.
    • Lancet Oncol. 2022 Jul;23(7):e314. doi: 10.1016/S1470-2045(22)00325-4.

    Letter, Reply:

    Rucaparib for recurrent ovarian cancer with BRCA1 and BRCA2 mutations - Authors' reply.

    Original research:

    Rucaparib versus standard-of-care chemotherapy in patients with relapsed ovarian cancer and a deleterious BRCA1 or BRCA2 mutation (ARIEL4): an international, open-label, randomised, phase 3 trial.

    • The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point.
    • Kalinowski L, Viale G, Domchek S, Tutt A, Lucas PC, Lakhani SR.
    • Pathology. 2022 Jun 28:S0031-3025(22)00174-X. doi: 10.1016/j.pathol.2022.05.003. Epub ahead of print.
    • Commentary
    • Efficacy of subsequent chemotherapy for patients with BRCA1/2-mutated recurrent epithelial ovarian cancer progressing on olaparib versus placebo maintenance: post-hoc analyses of the SOLO2/ENGOT Ov-21 trial.
    • Frenel JS, Kim JW, Aryal N, Asher R, Berton D, Vidal L, Pautier P, Ledermann JA, Penson RT, Oza AM, Korach J, Huzarski T, Pignata S, Colombo N, Park-Simon TW, Tamura K, Sonke GS, Freimund AE, Lee CK, Pujade-Lauraine E.
    • Ann Oncol. 2022 Jun 27:S0923-7534(22)01740-9. doi: 10.1016/j.annonc.2022.06.011. Epub ahead of print.
    • PARP Inhibitor Insensitivity to BRCA1/2 Monoallelic Mutations in Microsatellite Instability-High Cancers.
    • Sokol ES, Jin DX, Fine A, Trabucco SE, Maund S, Frampton G, Molinero L, Antonarakis ES.
    • JCO Precis Oncol. 2022 Jun;6:e2100531. doi: 10.1200/PO.21.00531.
    • Homologous Recombination Deficiency in Pancreatic Cancer: Poly (ADP-ribose) Polymerase Inhibition, Checkpoint Inhibition, or a Combination of Both?
    • Keane F, Park W, O'Reilly EM.
    • JCO Precis Oncol. 2022 Jun;6:e2200141. doi: 10.1200/PO.22.00141.

    Letter, Reply:

    Reply to F. Keane et al.

    Original research:

    Exceptional Response to Olaparib and Pembrolizumab for Pancreatic Adenocarcinoma With Germline BRCA1 Mutation and High Tumor Mutation Burden: Case Report and Literature Review.