LitAlert ~~ GeneLit.com

    • Re-treatment with PARPi in patients with recurrent epithelial ovarian cancer: A single institutional experience.
    • Moubarak M, Harter P, Ataseven B, Traut A, Welz J, Baert T, Heitz F.
    • Gynecol Oncol Rep. 2022 Feb 2 [eCollection 2022 Apr];40:100939. doi: 10.1016/j.gore.2022.100939.
    • Hereditary Breast and Ovarian Cancer: An Updated Primer for OB/GYNs.
    • Bellcross CA.
    • Obstet Gynecol Clin North Am. 2022 Mar;49(1):117-147. doi: 10.1016/j.ogc.2021.11.005.
    • Review
    • Evaluation of Hereditary/Familial Breast Cancer Patients with Multigene Targeted Next Generation Sequencing Panel and MLPA Analysis in Turkey.
    • Bora E, Caglayan AO, Koc A, Cankaya T, Ozkalayci H, Kocabey M, Kemer D, Aksoy S, Alicikus ZA, Akin IB, Durak MG, Gurel D, Yavuzsen T, Sevinc A, Somali I, Gorken I, Balci P, Karaoglu A, Saydam S, Ulgenalp A.
    • Cancer Genet. 2022 Feb 16. doi: 10.1016/j.cancergen.2022.02.006. Epub ahead of print.
    • Preclinical in vivo validation of the RAD51 test for identification of homologous recombination-deficient tumors and patient stratification.
    • Pellegrino B, Herencia-Ropero A, Llop-Guevara A, Pedretti F, Moles-Fernández A, Viaplana C, Villacampa G, Guzman M, Rodriguez O, Grueso J, Jimenez J, Arenas EJ, Degasperi A, Lopes. Dias JM, Forment JV, O'Connor MJ, Déas O, Cairo S, Zhou Y, Musolino A, Caldas C, Nik-Zainal S, Clarke RB, Nuciforo PG, Díez O, Serres-Créixams X, Peg V, Espinosa-Bravo M, Macarulla T, Oaknin A, Mateo J, Arribas J, Dienstmann R, Bellet M, Oliveira M, Saura C, Gutiérrez-Enríquez S, Balmaña J, Serra V.
    • Cancer Res. 2022 Feb 16:canres.2409.2021. doi: 10.1158/0008-5472.CAN-21-2409. Epub ahead of print.
    • Clinical Management of Prostate Cancer in High-Risk Genetic Mutation Carriers.
    • Clark R, Herrera-Caceres J, Kenk M, Fleshner N.
    • Cancers (Basel). 2022 Feb 16;14(4):1004. doi: 10.3390/cancers14041004.
    • Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer.
    • Tattersall A, Ryan N, Wiggans AJ, Rogozinska E, Morrison J.
    • Cochrane Database Syst Rev. 2022 Feb 16;2:CD007929. doi: 10.1002/14651858.CD007929.pub4.
    • Review
    • Prevalence of Germline Sequence Variations Among Patients With Pancreatic Cancer in China.
    • Yin L, Wei J, Lu Z, Huang S, Gao H, Chen J, Guo F, Tu M, Xiao B, Xi C, Zhang K, Li Q, Wu J, Gao W, Jiang K, Yu J, Miao Y.
    • JAMA Netw Open. 2022 Feb 16;5(2):e2148721. doi: 10.1001/jamanetworkopen.2021.48721.
    • Earlier decisions on breast and ovarian surgery reduce cancer in women at high risk.
    • Saul H, Gursul D, Cassidy S, Evans G.
    • BMJ. 2022 Feb 15;376:o258. doi: 10.1136/bmj.o258.
    • Research news

    Original research:

    Uptake and efficacy of bilateral risk reducing surgery in unaffected female BRCA1 and BRCA2 carriers.

    • Recurring pathogenic variants in the BRCA2 gene in the Ethiopian Jewish population. Founder mutations?
    • Ludman MD, Philipsborn SL, Hartmajer S, Shwartzman NS, Reinstein E.
    • Fam Cancer. 2022 Feb 15. doi: 10.1007/s10689-021-00255-z. Epub ahead of print.
    • Psychosocial outcome and health behaviour intent of breast cancer patients with BRCA1/2 and PALB2 pathogenic variants unselected by a priori risk.
    • Padmanabhan H, Hassan NT, Wong SW, Lee YQ, Lim J, Hasan SN, Yip CH, Teo SH, Thong MK, Mohd Taib NA, Yoon SY.
    • PLoS One. 2022 Feb 15;17(2):e0263675. doi: 10.1371/journal.pone.0263675.
    • Reclassification of Five BRCA1/2 Variants with Unknown Significance Using Complex Functional Study.
    • Bozsik A, Papp J, Grolmusz VK, Patócs A, Oláh E, Butz H.
    • Cancer Res Treat. 2022 Feb 8. doi: 10.4143/crt.2021.1078. Epub ahead of print.
    • Update Breast Cancer 2021 Part 5 - Advanced Breast Cancer.
    • Lüftner D, Schütz F, Stickeler E, Fasching PA, Janni W, Kolberg-Liedtke C, Kolberg HC, Thomssen C, Müller V, Fehm TN, Belleville E, Bader S, Untch M, Welslau M, Thill M, Tesch H, Ditsch N, Lux MP, Wöckel A, Aktas B, Schneeweiss A, Würstlein R, Hartkopf AD.
    • Geburtshilfe Frauenheilkd. 2022 Feb 11 [eCollection 2022 Feb];82(2):215-225. doi: 10.1055/a-1724-9569.