LitAlert ~~ GeneLit.com

    • Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883).
    • Hauke J, Harter P, Ernst C, Burges A, Schmidt S, Reuss A, Borde J, De Gregorio N, Dietrich D, El-Balat A, Kayali M, Gevensleben H, Hilpert F, Altmüller J, Heimbach A, Meier W, Schoemig-Markiefka B, Thiele H, Kimmig R, Nürnberg P, Kast K, Richters L, Sehouli J, Schmutzler RK, Hahnen E.
    • J Med Genet. 2020 Dec 3:jmedgenet-2020-107353. doi: 10.1136/jmedgenet-2020-107353. Epub ahead of print.

    • BRCAness as a prognostic indicator in patients with early breast cancer.
    • Liu L, Matsunaga Y, Tsurutani J, Akashi-Tanaka S, Masuda H, Ide Y, Hashimoto R, Inuzuka M, Watanabe C, Taruno K, Sawada T, Okuyama H, Ata A, Kuwayama T, Nakayama S, Tonouchi Y, Nakamura S.
    • Sci Rep. 2020 Dec 3;10(1):21173. doi: 10.1038/s41598-020-78016-8.

    • Combinatorial efficacy of olaparib with radiation and ATR inhibitor requires PARP1 protein in homologous recombination proficient pancreatic cancer.
    • Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA.
    • Mol Cancer Ther. 2020 Dec 2:molcanther.0365.2020. doi: 10.1158/1535-7163.MCT-20-0365. Epub ahead of print.

    • Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells.
    • Wu X, Li Q, Zhang F, Wang L, Wang J, Fan J, Di G, Guo C.
    • Food Chem Toxicol. 2020 Nov 30:111892. doi: 10.1016/j.fct.2020.111892. Epub ahead of print.

    • Locoregional treatments and ipsilateral breast cancer recurrence rates in BRCA1/2 mutation carriers.
    • Bernstein-Molho R, Laitman Y, Galper S, Jacobson G, Boursi B, Gal-Yam EN, Kaufman B, Friedman E, Kaidar-Person O.
    • Int J Radiat Oncol Biol Phys. 2020 Nov 28:S0360-3016(20)34598-3. doi: 10.1016/j.ijrobp.2020.11.058. Epub ahead of print.